Lars Holmgren
Professor | Head of department | Docent
E-mail: lars.holmgren@ki.se
Visiting address: J6:20 BioClinicum, Akademiska stråket 1, 17164 Solna
Postal address: K7 Onkologi-Patologi, K7 Övriga Holmgren, 171 77 Stockholm
About me
- Professor, tumor biology, Karolinska Institutet 2008-
Chairperson, Cancer theme U2/Bioclinicum 2012-
Chairperson, Karolinska consultative assembly, an 82-person body representing KI’s faculty, students and staff, 2012
Chairperson, Karolinska consultative faculty assembly, 2011-2013
Coordinator EU-consortium EUCAAD, 2008-2012
Member of advisory board Paoli Calmette Cancer Center, Marseille
External reviewer Vetenskapsrådet, Cancerfonden, Fernströms stiftelse, Internationella grants etc
Director of PhD studies, OnkPat, 2004-2014
Research
- My research is focused on studies how individual cells aggregate and form functional organs and how these processes are reversed during malignancy. To study these questions, my lab use a number in vitro and in vivo model systems. We also have access to patient materials to verify our pre-clinical findings.
Selected publications
- Article: NATURE COMMUNICATIONS. 2014;5:4557
- Article: NATURE COMMUNICATIONS. 2014;5:3743
- Article: SCIENCE SIGNALING. 2013;6(291):ra77
- Article: NATURE COMMUNICATIONS. 2013;4:1672
- Article: CANCER CELL. 2011;19(4):527-540
Articles
- Article: JOURNAL OF EXPERIMENTAL AND CLINICAL CANCER RESEARCH. 2024;43(1):107
- Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2024;44(3):666-689
- Article: CELLS. 2023;12(17):2158
- Article: NATURE CARDIOVASCULAR RESEARCH. 2023;2(7):629-644
- Article: CELLS. 2023;12(13):1682
- Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2022;79(10):535
- Article: CELL REPORTS. 2021;36(8):109616
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(10):5508-5522
- Article: PLOS BIOLOGY. 2019;17(5):e3000253
- Article: SCIENTIFIC REPORTS. 2017;7(1):9540
- Article: SCIENTIFIC REPORTS. 2017;7(1):7548
- Article: ACS NANO. 2017;11(7):7110-7117
- Article: SCIENTIFIC REPORTS. 2016;6:30622
- Article: ONCOIMMUNOLOGY. 2015;4(5):e1005500
- Article: EJNMMI RESEARCH. 2014;4(1):17
- Article: CIRCULATION. 2014;129(12):1295-1302
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2013;288(13):8991-9000
- Article: ANGIOGENESIS. 2012;15(2):305-316
- Article: FREE RADICAL BIOLOGY AND MEDICINE. 2011;50(7):811-820
- Article: MOLECULAR CANCER RESEARCH. 2010;8(9):1198-1206
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):147-151
- Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2009;36(8):1283-1295
- Article: CIRCULATION RESEARCH. 2009;105(3):260-270
- Article: CELL DEATH AND DIFFERENTIATION. 2009;16(5):749-757
- Article: BLOOD. 2009;113(1):244-253
- Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2008;1783(3):429-437
- Article: THE FASEB JOURNAL. 2008;22(3):880-889
- Article: GENES & DEVELOPMENT. 2007;21(16):2055-2068
- Article: FEBS LETTERS. 2007;581(16):2943-2946
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(24):9208-9213
- Article: THE FEBS JOURNAL. 2006;273(9):2000-2011
- Article: MOLECULAR CANCER RESEARCH. 2006;4(3):187-195
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(41):34859-34869
- Article: ONCOGENE. 2004;23(7):1469-1473
- Article: JOURNAL OF CELL SCIENCE. 2003;116(18):3803-3810
- Article: ANNALS OF SURGERY. 2003;237(4):530-535
- Article: MOLECULAR AND CELLULAR BIOLOGY. 2003;23(4):1260-1268
- Article: JOURNAL OF IMMUNOLOGY. 2002;169(10):5771-5779
- Article: GENE. 2002;298(1):69-77
- Article: CANCER RESEARCH. 2002;62(2):575-579
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(11):6407-6411
- Article: JOURNAL OF CELL BIOLOGY. 2001;152(6):1247-1254
- Article: JOURNAL OF IMMUNOLOGY. 1999;163(2):736-742
- Article: BLOOD. 1999;93(11):3956-3963
- Article: ANGIOGENESIS. 1999;3(4):291-293
- Article: BLOOD. 1998;92(12):4730-4741
- Article: ONCOGENE. 1998;17(7):819-824
- Article: NATURE MEDICINE. 1996;2(6):689-692
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1996;93(5):2002-2007
- Article: NATURE MEDICINE. 1995;1(2):149-153
- Show more
All other publications
- Review: DISEASE MODELS & MECHANISMS. 2023;16(10):dmm050361
- Corrigendum: GENE. 2003;310:221
- Published conference paper: VOX SANGUINIS. 2002;83:305-306
- Review: CANCER AND METASTASIS REVIEWS. 1996;15(2):241-245
Employments
- Professor, Department of Oncology-Pathology, Karolinska Institutet, 2008-
Degrees and Education
- Docent, Karolinska Institutet, 1998
Leadership and responsibility assignments
- Head of department, Department of Oncology-Pathology, Karolinska Institutet, 2021-