Kristina Hellman

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Articles

Article: CLINICAL CANCER RESEARCH. 2024;30(13):2764-2771

Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer

Sivars L; Jylha C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjold M; Tham E; Hellman K
Article: GYNECOLOGIC ONCOLOGY. 2024;186:69-76

Has time to chemotherapy from primary debulking surgery in advanced ovarian cancer an impact on survival?- A population-based nationwide SweGCG study

Dahm-Kahler P; Radestad AF; Holmberg E; Borgfeldt C; Bjurberg M; Skold C; Hellman K; Kjolhede P; Stalberg K; Avall-Lundqvist E
Article: ACTA ONCOLOGICA. 2023;62(12):1599-1606

Prevalence and predictors for fertility-related distress among 1010 young adults 1.5 years following cancer diagnosis - results from the population-based Fex-Can Cohort study

Rodriguez-Wallberg KA; Ahlgren J; Smedby KE; Gorman JR; Hellman K; Henriksson R; Stahl O; Wettergren L; Lampic C
Article: ACTA ONCOLOGICA. 2023;62(12):1649-1652

Prevalence of human papillomavirus (HPV) types 16 and 18 in cervical cancer in Stockholm, Sweden during 2019-2023 compared to 2003-2008

Sivars L; Holzhauser S; Ramqvist T; Tham E; Hellman K; Dalianis T
Journal article: ANNALS OF ONCOLOGY. 2023;34:s537

Cell-free human papillomavirus (HPV) DNA is a sensitive biomarker for monitoring treatment response and for detecting relapse in locally advanced cervical cancer

Sivars L; Tham E; Hellman K
Article: CANCER MEDICINE. 2023;12(8):9893-9901

Do young adults with cancer receive information about treatment- related impact on sex life? Results from a population-based study

Bergstrom C; Lampic C; Roy R; Hedman C; Ahlgren J; Stahl O; Smedby KE; Hellman K; Henriksson R; Eriksson LE; Wettergren L
Article: ACTA ONCOLOGICA. 2022;61(10):1165-1172

Prevalence and risk factors for sexual dysfunction in young women following a cancer diagnosis - a population-based study

Wettergren L; Eriksson LE; Bergstrom C; Hedman C; Ahlgren J; Smedby KE; Hellman K; Henriksson R; Lampic C
Article: GYNECOLOGIC ONCOLOGY. 2022;167(1):107-114

Circulating cell-free tumor human papillomavirus DNA is a promising biomarker in cervical cancer

Sivars L; Hellman K; Guterstam YC; Holzhauser S; Nordenskjold M; Falconer H; Palsdottir K; Tham E
Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2022;101(8):923-930

Long-term incidence of endometrial cancer after endometrial resection and ablation: A population based Swedish gynecologic cancer group (SweGCG) study

Radestad AF; Dahm-Kahler P; Holmberg E; Bjurberg M; Hellman K; Hogberg T; Kjolhede P; Marcickiewicz J; Rosenberg P; Stalberg K; Avall-Lundqvist E; Borgfeldt C
Article: ACTA ONCOLOGICA. 2022;61(1):30-37

The wait time to primary surgery in endometrial cancer - impact on survival and predictive factors: a population-based SweGCG study

Marcickiewicz J; Avall-Lundqvist E; Holmberg ECV; Borgfeldt C; Bjurberg M; Dahm-Kahler P; Floter-Radestad A; Hellman K; Hogberg T; Rosenberg P; Stalberg K; Kjolhede P
Journal article: CANCER CARE RESEARCH ONLINE. 2022;2(1):e019

Adaption of the Quality From the Patient’s Perspective Instrument for Use in Assessing Gynecological Cancer Care and Patients’ Perceptions of Quality Care Received

Olsson C; Wilde Larsson B; Larsson M; Holmberg E; Marcickiewicz J; Tholander B; Flöter-Rådestad A; Bjurberg M; Dahm-Kähler P; Hellman K; Kjølhede P; Stålberg K; Högberg T; Åvall Lundqvist E; Borgfeldt C
Article: ONCOLOGY LETTERS. 2022;23(1):30

Evaluation of dyskerin expression and the Cajal body protein WRAP53β as potential prognostic markers for patients with primary vaginal carcinoma

Ranhem C; Larsson G; Lindqvist D; Sorbe B; Karlsson M; Farnebo M; Hellman K; Kovaleska L; Kashuba E; Andersson S
Article: ACTA ONCOLOGICA. 2021;60(8):976-983

Fertility-related information received by young women and men with cancer - a population-based survey

Wide A; Wettergren L; Ahlgren J; Smedby KE; Hellman K; Henriksson R; Rodriguez-Wallberg K; Stahl O; Lampic C
Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2021;100(8):1526-1533

Preoperative and intraoperative assessment of myometrial invasion in endometrial cancer-A Swedish Gynecologic Cancer Group (SweGCG) study

Jonsdottir B; Marcickiewicz J; Borgfeldt C; Bjurberg M; Dahm-Kahler P; Floter-Radestad A; Hellman K; Holmberg E; Kjolhede P; Rosenberg P; Tholander B; Avall-Lundqvist E; Stalberg K; Hogberg T
Article: BMC CANCER. 2021;21(1):658

Survival in endometrial cancer in relation to minimally invasive surgery or open surgery - a Swedish Gynecologic Cancer Group (SweGCG) study

Borgfeldt C; Holmberg E; Marcickiewicz J; Stalberg K; Tholander B; Lundqvist EA; Floter-Radestad A; Bjurberg M; Dahm-Kahler P; Hellman K; Hjerpe E; Kjolhede P; Rosenberg P; Hogberg T
Article: GYNECOLOGIC ONCOLOGY. 2021;161(3):748-754

Patterns of recurrence and survival in vulvar cancer: A nationwide population-based study

Zach D; Avall-Lundqvist E; Falconer H; Hellman K; Johansson H; Radestad AF
Article: GYNECOLOGIC ONCOLOGY. 2021;161(1):244-250

Implementation of National Guidelines increased survival in advanced ovarian cancer-A population-based nationwide SweGCG study

Dahm-Kahler P; Holmberg E; Holtenman M; Radestad AF; Borgfeldt C; Hjerpe E; Marcickiewicz J; Bjurberg M; Tholander B; Hellman K; Kjolhede P; Hogberg T; Rosenberg P; Avall-Lundqvist E; Stalberg K
Journal article: JOURNAL OF CANCER METASTASIS AND TREATMENT. 2021;7:null

Uterine cervical carcinoma treated with chemoradiotherapy: impact of three-month MRI follow-up on clinical management and outcome

Sundstrom H; Blomqvist L; Hellman K
Article: GYNECOLOGIC ONCOLOGY. 2020;159(3):663-671

Primary treatment and relative survival by stage and age in vulvar squamous cell carcinoma: A population-based SweGCG study

Hellman K; Holmberg E; Bjurberg M; Borgfeldt C; Dahm-Kahler P; Radestad AF; Hjerpe E; Hogberg T; Marcickiewicz J; Rosenberg P; Stalberg K; Tholander B; Kjolhede P; Avall-Lundqvist E
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2019;381(25):2391-2402

Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer.

González-Martín A; Pothuri B; Vergote I; DePont Christensen R; Graybill W; Mirza MR; McCormick C; Lorusso D; Hoskins P; Freyer G; Baumann K; Jardon K; Redondo A; Moore RG; Vulsteke C; O'Cearbhaill RE; Lund B; Backes F; Barretina-Ginesta P; Haggerty AF; Rubio-Pérez MJ; Shahin MS; Mangili G; Bradley WH; Bruchim I; Sun K; Malinowska IA; Li Y; Gupta D; Monk BJ; PRIMA/ENGOT-OV26/GOG-3012 Investigators
Article: ACTA ONCOLOGICA. 2019;58(11):1628-1633

Lymphovascular space invasion as a predictive factor for lymph node metastases and survival in endometrioid endometrial cancer - a Swedish Gynecologic Cancer Group (SweGCG) study

Stalberg K; Bjurberg M; Borgfeldt C; Carlson J; Dahm-Kahler P; Floter-Radestad A; Hellman K; Hjerpe E; Holmberg E; Kjolhede P; Marcickiewicz J; Rosenberg P; Tholander B; Avall-Lundqvist E; Hogberg T
Article: GYNECOLOGIC ONCOLOGY. 2019;155(2):229-236

Primary treatment patterns and survival of cervical cancer in Sweden: A population-based Swedish Gynecologic Cancer Group Study

Bjurberg M; Holmberg E; Borgfeldt C; Floter-Radestad A; Dahm-Kahler P; Hjerpe E; Hogberg T; Kjolhede P; Marcickiewicz J; Rosenberg P; Stalberg K; Tholander B; Hellman K; Avall-Lundqvist E
Article: GYNECOLOGIC ONCOLOGY. 2019;152(3):560-567

Efficacy and safety of niraparib as maintenance treatment in older patients (≥ 70 years) with recurrent ovarian cancer: Results from the ENGOT-OV16/NOVA trial

Fabbro M; Moore KN; Dorum A; Tinker AV; Mahner S; Bover I; Banerjee S; Tognon G; Goffin F; Shapira-Frommer R; Wenham RM; Hellman K; Provencher D; Harter P; Palacio Vazquez I; Follana P; Pineda MJ; Mirza MR; Hazard SJ; Matulonis UA
Article: ACTA ONCOLOGICA. 2018;57(3):346-353

Data quality in the Swedish Quality Register of Gynecologic Cancer - a Swedish Gynecologic Cancer Group (SweGCG) study

Rosenberg P; Kjolhede P; Staf C; Bjurberg M; Borgfeldt C; Dahm-Kahler P; Hellman K; Hjerpe E; Holmberg E; Stalberg K; Tholander B; Lundqvist EA; Hogberg T
Article: ACTA ONCOLOGICA. 2018;57(3):331-337

Lymph node metastases as only qualifier for stage IV serous ovarian cancer confers longer survival than other sites of distant disease - a Swedish Gynecologic Cancer Group (SweGCG) study

Hjerpe E; Staf C; Dahm-Kahler P; Stalberg K; Bjurberg M; Holmberg E; Borgfeldt C; Tholander B; Hellman K; Kjolhede P; Hogberg T; Rosenberg P; Avall-Lundqvist E
Journal article: ANNALS OF ONCOLOGY. 2017;28:v332

934PD Safety and Efficacy of Niraparib in Elderly Patients (Pts) with Recurrent Ovarian Cancer (OC)

Fabbro M; Moore KN; Dørum A; Tinker AV; Mahner S; Bover I; Banerjee S; Tognon G; Goffin F; Shapira-Frommer R; Wenham RM; Hellman K; Provencher DM; Harter P; Vázquez IP; Follana P; Pineda MJ; Mirza MR; Hazard SJ; Matulonis UA
Article: PLOS ONE. 2017;12(8):e0183816

Expression of LRIG proteins as possible prognostic factors in primary vaginal carcinoma

Ranhem C; larsson GL; Hedman H; Lindquist D; Karlsson MG; Hellstrom A-C; Ostensson E; Sorbe B; Hellman K; Andersson S
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2016;375(22):2154-2164

Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer.

Mirza MR; Monk BJ; Herrstedt J; Oza AM; Mahner S; Redondo A; Fabbro M; Ledermann JA; Lorusso D; Vergote I; Ben-Baruch NE; Marth C; Mądry R; Christensen RD; Berek JS; Dørum A; Tinker AV; du Bois A; González-Martín A; Follana P; Benigno B; Rosenberg P; Gilbert L; Rimel BJ; Buscema J; Balser JP; Agarwal S; Matulonis UA; ENGOT-OV16/NOVA Investigators
Article: ACTA RADIOLOGICA OPEN. 2016;5(11):2058460116679460-205846011667946

Preoperative MR staging of cervical carcinoma: are oblique and contrast-enhanced sequences necessary?

Fridsten S; Hellström A-C; Hellman K; Sundin A; Söderén B; Blomqvist L
Article: CANCER MEDICINE. 2014;3(2):284-292

Uterine cervix cancer treatment at Radiumhemmet: 90 years' experience. Time trends of age, stage, and histopathology distribution

Hellman K; Hellstrom A-C; Pettersson BF
Article: BRITISH JOURNAL OF CANCER. 2014;110(6):1561-1570

Human papillomavirus, p16^INK4A, and Ki-67 in relation to clinicopathological variables and survival in primary carcinoma of the vagina

Hellman K; Lindquist D; Ranhem C; Wilander E; Andersson S
Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2013;92(7):830-840

Projected cost-effectiveness of repeat high-risk human papillomavirus testing using self-collected vaginal samples in the Swedish cervical cancer screening program

Ostensson E; Hellstrom A-C; Hellman K; Gustavsson I; Gyllensten U; Wilander E; Zethraeus N; Andersson S
Article: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2013;23(1):41-51

Prognostic Significance of Cell Cycle- and Invasion-Related Molecular Markers and Genomic Instability in Primary Carcinoma of the Vagina

Hellman K; Johansson H; Andersson S; Pettersson F; Auer G
Article: BRITISH JOURNAL OF CANCER. 2012;106(7):1297-1305

Impact of genomic stability on protein expression in endometrioid endometrial cancer

Lomnytska MI; Becker S; Gemoll T; Lundgren C; Habermann J; Olsson A; Bodin I; Engstrom U; Hellman U; Hellman K; Hellstrom A-C; Andersson S; Mints M; Auer G
Article: JOURNAL OF GYNECOLOGIC ONCOLOGY. 2011;22(2):76-82

Cervical cancer in the screening era: who fell victim in spite of successful screening programs?

Pettersson BF; Hellman K; Vaziri R; Andersson S; Hellstrom A-C
Article: ONCOLOGY REPORTS. 2011;25(6):1651-1654

Carcinoma of the cervical stump: Fifty years of experience

Hellstrom A-C; Hellman K; Pettersson BF; Andersson S
Article: BRITISH JOURNAL OF CANCER. 2011;104(1):110-119

Differential expression of ANXA6, HSP27, PRDX2, NCF2, and TPM4 during uterine cervix carcinogenesis: diagnostic and prognostic value

Lomnytska MI; Becker S; Bodin I; Olsson A; Hellman K; Hellstrom A-C; Mints M; Hellman U; Auer G; Andersson S
Article: CANCER. 2010;116(10):2343-2349

Invasive Carcinoma of the Uterine Cervix Associated With Pregnancy 90 Years of Experience

Pettersson BF; Andersson S; Hellman K; Hellstrom A-C
Article: PROTEOMICS CLINICAL APPLICATIONS. 2010;4(1):17-31

Diagnostic protein marker patterns in squamous cervical cancer

Lomnytska MI; Becker S; Hellman K; Hellstrom A-C; Souchelnytskyi S; Mints M; Hellman U; Andersson S; Auer G
Article: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2006;16(3):1201-1211

Clinical and histopathologic factors related to prognosis in primary squamous cell carcinoma of the vagina

Hellman K; Lundell M; Silfverswärd C; Nilsson B; Hellström AC; Frankendal B
Journal article: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2006;16(3):1201-1211

Clinical and histopathologic factors related to prognosis in primary squamous cell carcinoma of the vagina

Hellman K; Lundell M; Silfverswärd C; Nilsson B; Hellström AC; Frankendal B
Article: BRITISH JOURNAL OF CANCER. 2004;91(2):319-326

Protein expression patterns in primary carcinoma of the vagina

Hellman K; Alaiya AA; Schedvins K; Steinberg W; Hellström AC; Auer G
Journal article: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2004;14(3):491-501

Primary carcinoma of the vagina: factors influencing the age at diagnosis. The Radiumhemmet series 1956–96

HELLMAN K; SILFVERSWÄRD C; NILSSON B; HELLSTRÖM AC; FRANKENDAL B; PETTERSSON F
Article: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2004;14(3):491-501

Primary carcinoma of the vagina:: factors influencing the age at diagnosis.: The Radiumhemmet series 1956-96

Hellman K; Silfverswärd C; Nilsson B; Hellström AC; Frankendal B; Pettersson F
Article: CANCER GENETICS. 2004;148(1):7-13

A recurrent gain of chromosome arm 3q in primary squamous carcinoma of the vagina

Habermann JK; Hellman K; Freitag S; Heselmeyer-Haddad K; Hellström AC; Shah K; Auer G; Ried T
Article: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2000;10(5):391-396

Cancer of the vagina:: Laminin-5γ2 chain expression and prognosis

Hellman K; Hellström AC; Silfverswärd C; Salo S; Aspenblad U; Nilsson B; Frankendal B; Tryggvasson K; Auer G
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Conference publication: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2023;33:a22.1-a2a22

HAS TIME TO CHEMOTHERAPY FROM PRIMARY DEBULKING SURGERY IN ADVANCED OVARIAN CANCER AN IMPACT ON SURVIVAL? - A POPULATION-BASED NATIONWIDE SWEGCG STUDY

Dahm-Kahler P; Radestad AF; Holmberg E; Borgfeldt C; Bjurberg M; Skold C; Hellman K; Kjolhede P; Stalberg K; Avall-Lundqvist E
Review: INTERNATIONAL JOURNAL OF CANCER. 2023;152(11):2232-2242

The current status of cell-free human papillomavirus DNA as a biomarker in cervical cancer and other HPV-associated tumors: A review

Sivars L; Palsdottir K; Guterstam YC; Falconer H; Hellman K; Tham E
Letter: ACTA ONCOLOGICA. 2022;61(7):809-813

Cancer in young adulthood - classifying the intensity of treatment

Hedman C; Ahlgren J; Smedby KE; Hellman K; Henriksson R; Stahl O; Wettergren L; Lampic C
Conference publication: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2020;30:A16-A17

PATTERNS OF RECURRENCE IN VULVAR CANCER: A NATIONWIDE POPULATION-BASED STUDY

Zach D; Lundqvist EA; Lundqvist HA; Hemming J; Hellman K; Radestad AF
Conference publication: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2020;30:A192

COMPARISON OF DIFFERENT METHODS TO DETERMINE MYOMETRIAL INVASION IN ENDOMETRIAL CANCER - A NATIONWIDE SWEGCG STUDY

Bjorg J; Bjurberg M; Borgfeldt C; Dahm-Kahler P; Floter-Radestad A; Hellman K; Hjerpe E; Holmberg E; Kjolhede P; Marcickiewicz J; Rosenberg P; Tholander B; Avall-Lundquist E; Stalberg K; Hogberg T
Conference publication: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2019;29:A166-A167

TREATMENT AND RELATIVE SURVIVAL OF VULVAR CARCINOMA IN SWEDEN 2012-16. A POPULATION-BASED COHORT (SWEGCG STUDY)

Hellman K; Borgfeldt C; Dahm-Kahler P; Radestad AF; Hjerpe E; Holmberg E; Hogberg T; Marcickiewicz J; Stalberg K; Rosenberg P; Tholander B; Kjolhede P; Avall-Lundqvist E
Conference publication: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2019;29:A131

CENTRALIZATION AND IMPLEMENTATION OF NATIONAL GUIDELINES OF OVARIAN CANCER IMPROVES SURVIVAL - A POPULATION-BASED NATIONWIDE SWEGCG STUDY

Kahler PD; Borgfeldt C; Radestad AF; Hjerpe E; Marcickiewicz J; Bjurberg M; Tholander B; Hellman K; Kjolhede P; Hogberg T; Rosenberg P; Avall-Lundqvist E; Stalberg K
Conference publication: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2019;29:A6

LYMPHO-VASCULAR SPACE INVASION IS STRONGLY ASSOCIATED WITH LYMPH NODE METASTASES AND DECREASED SURVIVAL IN ENDOMETRIOID ENDOMETRIAL CANCER: A SWEDISH GYNECOLOGIC CANCER GROUP (SWEGCG) STUDY

Stalberg K; Bjurberg M; Borgfeldt C; Carlson J; Kahler PD; Floter-Radestad A; Hellman K; Hjerpe E; Holmberg E; Kjolhede P; Marcickiewicz J; Rosenberg P; Tholander B; Avall-Lundqvist E; Hogberg T
Meeting abstract: JOURNAL OF CLINICAL ONCOLOGY. 2017;35:5517

Efficacy of niraparib on progression-free survival (PFS) in patients (pts) with recurrent ovarian cancer (OC) with partial response (PR) to the last platinum-based chemotherapy

Mirza MR; Monk BJ; Gil-Martin M; Gilbert L; Canzler U; Follana P; Waters JS; Kridelka F; Levy T; Benigno BB; Woie K; Provencher DM; Lueck H-J; Herraez AC; Lesoin A; Buscema J; Hellman K; Rimel BJ; Hazard S; Matulonis UA
Conference publication: ANNALS OF ONCOLOGY. 2017;28

Safety and Efficacy of Niraparib in Elderly Patients (Pts) with Recurrent Ovarian Cancer (OC)

Fabbro M; Moore KN; Dorum A; Tinker AV; Mahner S; Bover I; Banerjee S; Tognon G; Goffin F; Shapira-Frommer R; Wenham RM; Hellman K; Provencher DM; Harter P; Palacio Vazquez I; Follana P; Pineda MJ; Mirza MR; Hazard SJ; Matulonis UA
Conference publication: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2014;24(9):892

PREVALENCE OF HPV-POSITIVE VAGINAL AND VULVAR CANCER OVER TIME IN TWO SWEDISH COHORTS

Lindquist D; Ranhem C; Stefansson K; Hellman K; Andersson S
Conference publication: CANCER RESEARCH. 2011;71:5076

Multi-protein tissue and blood plasma protein marker patterns of endometrioid endometrial and squamous cervical cancers

Lomnytska M; Becker S; Hellman U; Engstrom U; Hellstrom A-C; Hellman K; Lundgren C; Andersson S; Mints M; Auer G
Review: BRITISH JOURNAL OF CANCER. 2009;100(8):1303-1314

Differential tissue-specific protein markers of vaginal carcinoma

Hellman K; Alaiya AA; Becker S; Lomnytska M; Schedvins K; Steinberg W; Hellstrom A-C; Andersson S; Hellman U; Auer G
Thesis / dissertation: 2005

Vaginal carcinoma : studies on etiology and prognostic factors

Hellman, Kristina

Grants

Web-based treatment of fertility-related distress and sexual problems after cancer – a randomized controlled pilot trial testing the Fex-Can 2.0 program

Swedish Research Council

1 January 2023 - 31 December 2025

Employments

Affiliated to Research, Department of Oncology-Pathology, Karolinska Institutet, 2022-2025

Degrees and Education

Docent, Cancer and Oncology, Karolinska Institutet, 2023
Associate Professor, Cancer and Oncology, Department of Oncology and Pathology, Karolinska Institutet, 2023
Doctor Of Philosophy, Department of Oncology-Pathology, Karolinska Institutet, 2005
University Medical Degree, Karolinska Institutet, 1990

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