Proteomics Biomedicum Core Facility - related publications

Recent projects

Genetic variants and down-regulation of CACNA1H in pheochromocytoma.
Svahn F, Solhusløkk Höse K, Stenman A, Liu Y, Calissendorff J, Tham E, Végvári Á, Zubarev RA, Wang N, Korah R, Carling T, Zedenius J, Bränström R, Juhlin CC, Larsson C
Endocr Relat Cancer 2024 Sep;31(9):

A cell autonomous regulator of neuronal excitability modulates tau in Alzheimer's disease vulnerable neurons.
Rodriguez-Rodriguez P, Arroyo-Garcia LE, Tsagkogianni C, Li L, Wang W, Végvári Á, Salas-Allende I, Plautz Z, Cedazo-Minguez A, Sinha SC, Troyanskaya O, Flajolet M, Yao V, Roussarie JP
Brain 2024 Jul;147(7):2384-2399

Proteomic analysis of the urothelial cancer landscape.
Dressler FF, Diedrichs F, Sabtan D, Hinrichs S, Krisp C, Gemoll T, Hennig M, Mackedanz P, Schlotfeldt M, Voß H, Offermann A, Kirfel J, Roesch MC, Struck JP, Kramer MW, Merseburger AS, Gratzke C, Schoeb DS, Miernik A, Schlüter H, Wetterauer U, Zubarev R, Perner S, Wolf P, Végvári Á
Nat Commun 2024 May;15(1):4513

Botryococcus braunii autolysate for the production of deuterium-labeled recombinant protein
Korusa K, Krupinska E, Sele C, Végvári A, Knecht W, Fisher SZ
Algal Research, 79:103459, 2024

Toward Single Bacterium Proteomics
Végvári A, Zhang X, Zubarev RA
J. Am. Soc. Mass Spectrom. 2023, 34, 10, 2098–2106

Systems-level temporal immune-metabolic profile in Crimean-Congo hemorrhagic fever virus infection.
Ambikan AT, Elaldi N, Svensson-Akusjärvi S, Bagci B, Pektas AN, Hewson R, Bagci G, Arasli M, Appelberg S, Mardinoglu A, Sood V, Végvári Á, Benfeitas R, Gupta S, Cetin I, Mirazimi A, Neogi U
Proc Natl Acad Sci U S A 2023 Sep;120(37):e2304722120

Analysis of local extracellular matrix identifies different aetiologies behind bicuspid and tricuspid aortic valve degeneration and suggests therapies.
Beusch CM, Simonson OE, Wedin JO, Sabatier P, Felldin U, Kadekar S, Österholm C, Végvári Á, Zubarev RA, Fromell K, Nilson B, James S, Ståhle E, Grinnemo KH, Rodin S
Cell Mol Life Sci 2023 Aug;80(9):268

Non-typeable Haemophilus influenzae major outer membrane protein P5 contributes to bacterial membrane stability, and affects the membrane protein composition crucial for interactions with the human host.
Su YC, Kadari M, Straw ML, Janoušková M, Jonsson S, Thofte O, Jalalvand F, Matuschek E, Sandblad L, Végvári Á, Zubarev RA, Riesbeck K
Front Cell Infect Microbiol 2023 ;13():1085908

eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration.
Chen J, Wang J, Wu X, Simon N, Svensson CI, Yuan J, Hart DA, Ahmed AS, Ackermann PW
Cell Mol Life Sci 2023 Apr;80(5):128

Brain endothelial cells exposure to malaria parasites links type I interferon signalling to antigen presentation, immunoproteasome activation, endothelium disruption, and cellular metabolism.
Shafi AM, Végvári Á, Zubarev RA, Penha-Gonçalves C
Front Immunol 2023 ;14():1149107

Single-Cell Chemical Proteomics (SCCP) Interrogates the Timing and Heterogeneity of Cancer Cell Commitment to Death.
Végvári Á, Rodriguez JE, Zubarev RA
Anal Chem 2022 Jul;94(26):9261-9269

Mass Spectrometry-Based Analytical Strategy for Single-Cell Proteomics.
Végvári Á
Methods Mol Biol 2022 ;2420():63-72