KCTT Publication list - Rederivation

BHLHE40/41 regulate microglia and peripheral macrophage responses associated with Alzheimer's disease and other disorders of lipid-rich tissues.
Podleśny-Drabiniok A, Novikova G, Liu Y, Dunst J, Temizer R, Giannarelli C, Marro S, Kreslavsky T, Marcora E, Goate AM
Nat Commun 2024 Mar;15(1):2058

BCG infection dose guides dendritic cell migration and T cell priming in the draining lymph node.
Krmeská V, Shen L, Nylén S, Wowk PF, Rothfuchs AG
Scand J Immunol 2024 Mar;99(3):e13342

Molecularly stratified hypothalamic astrocytes are cellular foci for obesity.
Harkany T, Tretiakov E, Varela L, Jarc J, Rebernik P, Newbold S, Keimpema E, Verkhratsky A, Horvath T, Romanov R
Res Sq 2024 Feb;():

Corpora cavernosa fibroblasts mediate penile erection.
Guimaraes EL, Dias DO, Hau WF, Julien A, Holl D, Garcia-Collado M, Savant S, Vågesjö E, Phillipson M, Jakobsson L, Göritz C
Science 2024 Feb;383(6683):eade8064

Co-expression of PADI isoforms during progenitor differentiation enables functional diversity.
Vikhe Patil K, Meijer M, Mak KH, Yang W, Falcão AM, Castelo-Branco G, Genander M
Philos Trans R Soc Lond B Biol Sci 2023 Nov;378(1890):20220451

Transcriptomic survey of key reproductive and metabolic tissues in mouse models of polycystic ovary syndrome.
Pei Y, Risal S, Jiang H, Lu H, Lindgren E, Stener-Victorin E, Deng Q
Commun Biol 2023 Jan;6(1):69

Glutarate regulates T cell metabolism and anti-tumour immunity.
Minogue E, Cunha PP, Wadsworth BJ, Grice GL, Sah-Teli SK, Hughes R, Bargiela D, Quaranta A, Zurita J, Antrobus R, Velica P, Barbieri L, Wheelock CE, Koivunen P, Nathan JA, Foskolou IP, Johnson RS
Nat Metab 2023 Oct;5(10):1747-1764

Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes.
Milenkovic D, Misic J, Hevler JF, Molinié T, Chung I, Atanassov I, Li X, Filograna R, Mesaros A, Mourier A, Heck AJR, Hirst J, Larsson NG
Cell Metab 2023 Oct;35(10):1799-1813.e7

Infiltration of Tumors Is Regulated by T cell-Intrinsic Nitric Oxide Synthesis.
Cunha PP, Bargiela D, Minogue E, Krause LCM, Barbieri L, Brombach C, Gojkovic M, Marklund E, Pietsch S, Foskolou I, Branco CM, Veliça P, Johnson RS
Cancer Immunol Res 2023 Mar;11(3):351-363

Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and regeneration.
Correia JC, Jannig PR, Gosztyla ML, Cervenka I, Ducommun S, Præstholm SM, Dumont K, Liu Z, Liang Q, Edsgärd D, Emanuelsson O, Gregorevic P, Westerblad H, Venckunas T, Brazaitis M, Kamandulis S, Lanner JT, Yeo GW, Ruas JL
bioRxiv 2023 Jun;():

Enhanced B Cell Receptor Signaling Partially Compensates for Impaired Toll-like Receptor 4 Responses in LPS-Stimulated IκBNS-Deficient B Cells.
Adori M, Khoenkhoen S, Zhang J, Dopico XC, Karlsson Hedestam GB
Cells 2023 Apr;12(9):

MHC Class I-Dependent Shaping of the NK Cell Ly49 Receptor Repertoire Takes Place Early during Maturation in the Bone Marrow.
Wickström SL, Wagner AK, Fuchs S, Elemans M, Kritikou J, Mehr R, Kärre K, Johansson MH, Brauner H
J Immunol 2022 Aug;209(4):751-759

Impaired Aversive Memory Formation in GPR37L1KO Mice.
Veenit V, Zhang X, Paslawski W, Mantas I, Svenningsson P
Int J Mol Sci 2022 Nov;23(22):

PRC2-mediated repression is essential to maintain identity and function of differentiated dopaminergic and serotonergic neurons.
Toskas K, Yaghmaeian-Salmani B, Skiteva O, Paslawski W, Gillberg L, Skara V, Antoniou I, Södersten E, Svenningsson P, Chergui K, Ringnér M, Perlmann T, Holmberg J
Sci Adv 2022 Aug;8(34):eabo1543

Recombinant multimeric dog allergen prevents airway hyperresponsiveness in a model of asthma marked by vigorous TH 2 and TH 17 cell responses.
Stark JM, Liu J, Tibbitt CA, Christian M, Ma J, Wintersand A, Dunst J, Kreslavsky T, Murrell B, Adner M, Grönlund H, Gafvelin G, Coquet JM
Allergy 2022 Oct;77(10):2987-3001

Brown-fat-mediated tumour suppression by cold-altered global metabolism.
Seki T, Yang Y, Sun X, Lim S, Xie S, Guo Z, Xiong W, Kuroda M, Sakaue H, Hosaka K, Jing X, Yoshihara M, Qu L, Li X, Chen Y, Cao Y
Nature 2022 Aug;608(7922):421-428

Bhlhe40 function in activated B and TFH cells restrains the GC reaction and prevents lymphomagenesis.
Rauschmeier R, Reinhardt A, Gustafsson C, Glaros V, Artemov AV, Dunst J, Taneja R, Adameyko I, Månsson R, Busslinger M, Kreslavsky T
J Exp Med 2022 Feb;219(2):

The WASp L272P gain-of-function mutation alters dendritic cell coordination of actin dynamics for migration and adhesion.
Oliveira MMS, Kung SY, Moreau HD, Maurin M, Record J, Sanséau D, Nylén S, Lennon-Duménil AM, Westerberg LS
J Leukoc Biol 2022 Apr;111(4):793-803

Mammalian RNase H1 directs RNA primer formation for mtDNA replication initiation and is also necessary for mtDNA replication completion.
Misic J, Milenkovic D, Al-Behadili A, Xie X, Jiang M, Jiang S, Filograna R, Koolmeister C, Siira SJ, Jenninger L, Filipovska A, Clausen AR, Caporali L, Valentino ML, La Morgia C, Carelli V, Nicholls TJ, Wredenberg A, Falkenberg M, Larsson NG
Nucleic Acids Res 2022 Aug;50(15):8749-8766

Targeted activation of midbrain neurons restores locomotor function in mouse models of parkinsonism.
Masini D, Kiehn O
Nat Commun 2022 Jan;13(1):504

HIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection.
Liu R, Muliadi V, Mou W, Li H, Yuan J, Holmberg J, Chambers BJ, Ullah N, Wurth J, Alzrigat M, Schlisio S, Carow B, Larsson LG, Rottenberg ME
Nat Commun 2022 Sep;13(1):5093

Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel-Lindau syndrome.
Li S, Li W, Yuan J, Bullova P, Wu J, Zhang X, Liu Y, Plescher M, Rodriguez J, Bedoya-Reina OC, Jannig PR, Valente-Silva P, Yu M, Henriksson MA, Zubarev RA, Smed-Sörensen A, Suzuki CK, Ruas JL, Holmberg J, Larsson C, Christofer Juhlin C, von Kriegsheim A, Cao Y, Schlisio S
Nat Metab 2022 Jun;4(6):739-758

Cyclooxygenase-Derived Prostaglandin E2 Drives IL-1-Independent Mycobacterium bovis Bacille Calmette-Guérin-Triggered Skin Dendritic Cell Migration to Draining Lymph Node.
Krmeská V, Aggio JB, Nylén S, Wowk PF, Rothfuchs AG
J Immunol 2022 Jun;208(11):2549-2557

IκBNS expression in B cells is dispensable for IgG responses to T cell-dependent antigens.
Khoenkhoen S, Ádori M, Solís-Sayago D, Soulier J, Russell J, Beutler B, Pedersen GK, Karlsson Hedestam GB
Front Immunol 2022 ;13():1000755

Altered developmental programs and oriented cell divisions lead to bulky bones during salamander limb regeneration.
Kaucka M, Joven Araus A, Tesarova M, Currie JD, Boström J, Kavkova M, Petersen J, Yao Z, Bouchnita A, Hellander A, Zikmund T, Elewa A, Newton PT, Fei JF, Chagin AS, Fried K, Tanaka EM, Kaiser J, Simon A, Adameyko I
Nat Commun 2022 Nov;13(1):6949

ID1 and CEBPA coordinate epidermal progenitor cell differentiation.
Kantzer CG, Yang W, Grommisch D, Vikhe Patil K, Mak KH, Shirokova V, Genander M
Development 2022 Nov;149(22):

Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation.
He M, Saeed MB, Record J, Keszei M, Gonçalves Pinho L, Vasconcelos-Fontes L, D'Aulerio R, Vieira R, Oliveira MMS, Geyer C, Bohaumilitzky L, Thiemann M, Deordieva E, Buedts L, Matias Lopes JP, Pershin D, Hammarström L, Xia Y, Zhao X, Cunningham-Rundles C, Thrasher AJ, Burns SO, Cotta-de-Almeida V, Liu C, Shcherbina A, Vandenberghe P, Westerberg LS
J Allergy Clin Immunol 2022 Mar;149(3):1069-1084

B cell expansion hinders the stroma-epithelium regenerative cross talk during mucosal healing.
Frede A, Czarnewski P, Monasterio G, Tripathi KP, Bejarano DA, Ramirez Flores RO, Sorini C, Larsson L, Luo X, Geerlings L, Novella-Rausell C, Zagami C, Kuiper R, Morales RA, Castillo F, Hunt M, Mariano LL, Hu YOO, Engblom C, Lennon-Duménil AM, Mittenzwei R, Westendorf AM, Hövelmeyer N, Lundeberg J, Saez-Rodriguez J, Schlitzer A, Das S, Villablanca EJ
Immunity 2022 Dec;55(12):2336-2351.e12

Impaired plasma cell differentiation associates with increased oxidative metabolism in IκBNS-deficient B cells.
Erikson E, Ádori M, Khoenkhoen S, Zhang J, Rorbach J, Castro Dopico X, Karlsson Hedestam G
Cell Immunol 2022 May;375():104516

Distinct subtypes of proprioceptive dorsal root ganglion neurons regulate adaptive proprioception in mice.
Wu H, Petitpré C, Fontanet P, Sharma A, Bellardita C, Quadros RM, Jannig PR, Wang Y, Heimel JA, Cheung KKY, Wanderoy S, Xuan Y, Meletis K, Ruas J, Gurumurthy CB, Kiehn O, Hadjab S, Lallemend F
Nat Commun 2021 Feb;12(1):1026

Modified Hypoxia-Inducible Factor Expression in CD8+ T Cells Increases Antitumor Efficacy.
Veliça P, Cunha PP, Vojnovic N, Foskolou IP, Bargiela D, Gojkovic M, Rundqvist H, Johnson RS
Cancer Immunol Res 2021 Apr;9(4):401-414

Prenatal androgen exposure causes a sexually dimorphic transgenerational increase in offspring susceptibility to anxiety disorders.
Risal S, Manti M, Lu H, Fornes R, Larsson H, Benrick A, Deng Q, Cesta CE, Rosenqvist MA, Stener-Victorin E
Transl Psychiatry 2021 Jan;11(1):45

Demise of nociceptive Schwann cells causes nerve retraction and pain hyperalgesia.
Rinwa P, Calvo-Enrique L, Zhang MD, Nyengaard JR, Karlsson P, Ernfors P
Pain 2021 Jun;162(6):1816-1827

Liver X receptor regulates Th17 and RORγt+ Treg cells by distinct mechanisms.
Parigi SM, Das S, Frede A, Cardoso RF, Tripathi KP, Doñas C, Hu YOO, Antonson P, Engstrand L, Gustafsson JÅ, Villablanca EJ
Mucosal Immunol 2021 Mar;14(2):411-419

Role of T cells during the cerebral infection with Trypanosoma brucei.
Olivera GC, Vetter L, Tesoriero C, Del Gallo F, Hedberg G, Basile J, Rottenberg ME
PLoS Negl Trop Dis 2021 Sep;15(9):e0009764

CD36 and LC3B initiated autophagy in B cells regulates the humoral immune response.
He C, Wang S, Zhou C, He M, Wang J, Ladds M, Lianoudaki D, Sedimbi SK, Lane DP, Westerberg LS, Li S, Karlsson MCI
Autophagy 2021 Nov;17(11):3577-3591

Oxygen-Mediated Suppression of CD8+ T Cell Proliferation by Macrophages: Role of Pharmacological Inhibitors of HIF Degradation.
Gojkovic M, Cunha PP, Darmasaputra GS, Barbieri L, Rundqvist H, Veliça P, Johnson RS
Front Immunol 2021 ;12():633586

Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response.
Glaros V, Rauschmeier R, Artemov AV, Reinhardt A, Ols S, Emmanouilidi A, Gustafsson C, You Y, Mirabello C, Björklund ÅK, Perez L, King NP, Månsson R, Angeletti D, Loré K, Adameyko I, Busslinger M, Kreslavsky T
Immunity 2021 Sep;54(9):2005-2023.e10

SOCS3 Expression by Thymic Stromal Cells Is Required for Normal T Cell Development.
Gao Y, Liu R, He C, Basile J, Vesterlund M, Wahren-Herlenius M, Espinoza A, Hokka-Zakrisson C, Zadjali F, Yoshimura A, Karlsson M, Carow B, Rottenberg ME
Front Immunol 2021 ;12():642173

Mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response.
Filograna R, Lee S, Tiklová K, Mennuni M, Jonsson V, Ringnér M, Gillberg L, Sopova E, Shupliakov O, Koolmeister C, Olson L, Perlmann T, Larsson NG
PLoS Genet 2021 Sep;17(9):e1009822

Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity.
Correia JC, Kelahmetoglu Y, Jannig PR, Schweingruber C, Shvaikovskaya D, Zhengye L, Cervenka I, Khan N, Stec M, Oliveira M, Nijssen J, Martínez-Redondo V, Ducommun S, Azzolini M, Lanner JT, Kleiner S, Hedlund E, Ruas JL
Cell Metab 2021 Nov;33(11):2215-2230.e8

High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo.
Bonekamp NA, Jiang M, Motori E, Garcia Villegas R, Koolmeister C, Atanassov I, Mesaros A, Park CB, Larsson NG
Life Sci Alliance 2021 Nov;4(11):

Identification and characterization of distinct cell cycle stages in cardiomyocytes using the FUCCI transgenic system.
Baniol M, Murganti F, Smialowska A, Panula J, Lázár E, Brockman V, Giatrellis S, Derks W, Bergmann O
Exp Cell Res 2021 Nov;408(2):112880

A Neuro-hormonal Circuit for Paternal Behavior Controlled by a Hypothalamic Network Oscillation.
Stagkourakis S, Smiley KO, Williams P, Kakadellis S, Ziegler K, Bakker J, Brown RSE, Harkany T, Grattan DR, Broberger C
Cell 2020 Aug;182(4):960-975.e15

PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination.
Falcão AM, Meijer M, Scaglione A, Rinwa P, Agirre E, Liang J, Larsen SC, Heskol A, Frawley R, Klingener M, Varas-Godoy M, Raposo AASF, Ernfors P, Castro DS, Nielsen ML, Casaccia P, Castelo-Branco G
Cell Rep 2019 Apr;27(4):1090-1102.e10

Blastocyst genotyping for quality control of mouse mutant archives: an ethical and economical approach.
Scavizzi F, Ryder E, Newman S, Raspa M, Gleeson D, Wardle-Jones H, Montoliu L, Fernandez A, Dessain ML, Larrigaldie V, Khorshidi Z, Vuolteenaho R, Soininen R, André P, Jacquot S, Hong Y, de Angelis MH, Ramirez-Solis R, Doe B
Transgenic Res 2015 Oct;24(5):921-7