Kristian Dreij

Kristian Dreij

Principal Researcher | Docent
Visiting address: Nobels väg 13, 17177 Stockholm
Postal address: C6 Institutet för miljömedicin, C6 Biokemisk toxikologi Dreij, 171 77 Stockholm

About me

  • Head of Unit and Research Group Leader at the Institute of Environmental Medicine, Karolinska Institutet.

    I received my Ph.D. in Toxicology in 2005 from the laboratory of Prof. Jernström at KI. My research focused on the protective role of cellular metabolism and DNA repair against carcinogenic environmental contaminants. Following my Ph.D., I worked as a postdoctoral fellow in the laboratory of Prof. Scicchitano at the Department of Biology, New York University, where our project focused on the effects of chemical interactions with DNA and how cells deal with the resulting damage.

    My current research aims to shift the focus from studying the genotoxic effects of single chemicals to understanding the effects of complex mixtures found in our environment. We investigate genotoxicity in exposed populations and on human cells using environmental samples. This allows us to identify mechanisms of mixture toxicity and improve health risk assessment of environmental pollution. Current projects focus on urban and rural air pollution, and past projects have investigated genotoxic mixture effects in the context of soil contamination, indoor air quality in pre-schools, and occupational exposure to pesticides in Bolivia. We also study the effects of genotoxic chemicals and mixtures on transcription and replication fidelity by analyzing RNA and DNA mutagenesis.

    In 2016, I was appointed Associate Professor/Docent in Toxicology, and I am also Deputy Program Director of the global Master's Programme in Toxicology at Karolinska Institutet.

Selected publications


All other publications



  • Principal Researcher, Institute of Environmental Medicine, Karolinska Institutet, 2022-

Degrees and Education

  • Docent, Karolinska Institutet, 2016
  • Doctor Of Philosophy, Institute of Environmental Medicine, Karolinska Institutet, 2005

Leadership and responsibility assignments

  • Deputy Programme Director, Master's Programme in Toxicology, Institute of Environmental Medicine, Karolinska Institute, 2012-


  • Jessika Barrón Cuenca, Genotoxic effects among Bolivian farmers exposed to mixtures of pesticides : population and in vitro based studies,
  • Monika Ezerskyte, The impact of transcriptional mutagenesis on cellular homeostasis,
  • Sandeep Kadekar, Gender differences in chemical carcinogenesis,
  • Carla Martins, Carcinogenic toxicants and emerging pollutants. A comprehensive case-study on toxicant interactions in vivo and in vitro: from Molecular Toxicology to Environmental Risk Assessment,

News from KI

Events from KI