The interplay between circadian 3D genome organization and metabolism in complex diseases – Anita Göndör's Group

Our group combines basic research on 4D genome biology with translational research on circadian medicine. We thus aim at understanding the regulation of circadian transcription within the compartmentalised, 3D architecture of the nucleus and its role in adaptive responses. We moreover aim at uncovering how deregulated circadian genome organization contributes to complex diseases, such as cancer and endocrine-metabolic diseases.

Part of the:

Department of Oncology-Pathology

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Publications
Staff and contact

Publications

Selected publications

Article: NATURE GENETICS. 2019;51(12):1723-1731
WNT signaling and AHCTF1 promote oncogenic MYC expression through super-enhancer-mediated gene gating
Scholz BA; Sumida N; de Lima CDM; Chachoua I; Martino M; Tzelepis I; Nikoshkov A; Zhao H; Mehmood R; Sifakis EG; Bhartiya D; Gondor A; Ohlsson R
Journal article: SCIENCE. 2018;359(6381):1212-1213
Circadian organization of the genome
de Lima CDM; Gondor A
Review: NATURE REVIEWS GENETICS. 2016;17(5):284-299
Epigenetic modulators, modifiers and mediators in cancer aetiology and progression
Feinberg AP; Koldobskiy MA; Gondor A
Article: MOLECULAR CELL. 2015;59(6):984-997
PARP1-and CTCF-Mediated Interactions between Active and Repressed Chromatin at the Lamina Promote Oscillating Transcription
Zhao H; Sifakis EG; Sumida N; Millan-Arino L; Scholz BA; Svensson JP; Chen X; Ronnegren AL; de Lima CDM; Varnoosfaderani FS; Shi C; Loseva O; Yammine S; Israelsson M; Rathje L-S; Nemeti B; Fredlund E; Helleday T; Imreh MP; Gondor A
Review: NATURE. 2009;461(7261):212-217
Chromosome crosstalk in three dimensions
Gondor A; Ohlsson R
Review: NATURE REVIEWS GENETICS. 2009;10(4):269-276
OPINION Replication timing and epigenetic reprogramming of gene expression: a two-way relationship?
Gondor A; Ohlsson R
Article: NATURE PROTOCOLS. 2008;3(2):303-313
High-resolution circular chromosome conformation capture assay
Gondor A; Rougier C; Ohlsson R

Staff and contact

Group leader

Anita Göndör
Principal Researcher | Docent
Telephone +46852481201
E-mail anita.gondor@ki.se

All members of the group

Felipe Beccaria Casagrande
Postdoctoral Researcher
E-mail felipe.casagrande@ki.se
Mehdi Dehghan Manshadi
Postdoctoral Researcher
E-mail mehdi.dehghan.manshadi@ki.se
Wei Feng
Postdoctoral Studies
E-mail wei.feng@ki.se
Chen-ying Gao
Postdoctoral Studies
E-mail chenying.gao@ki.se
Anita Göndör
Principal Researcher | Docent
Telephone +46852481201
E-mail anita.gondor@ki.se
Sneha Karthikeyan
Affiliated to Research
E-mail sneha.karthikeyan@ki.se
Narsis Kiani
Senior Research Specialist
E-mail narsis.kiani@ki.se
Pragyan Mishra
Postdoctoral Studies
E-mail pragyan.mishra@ki.se
Rolf Ohlsson
Professor, Senior
Telephone +46852481219
E-mail rolf.ohlsson@ki.se
Mallikarjuna Thippana
Postdoctoral Studies
E-mail mallikarjuna.thippana@ki.se
Dennis Torkornoo
Postdoctoral Studies
E-mail dennis.torkornoo@ki.se