Anita Göndör

About me
Publications
Grants
CV
Public outreach and news

About me

Associate Professor in Medical Genetics, Department of Oncology-Pathology, Karolinska Institutet, 2020

Professor at the University of Oslo, 2023

Research

Our group combines basic research on 4D genome biology with translational research on circadian medicine. We thus aim at understanding the regulation of circadian transcription within the compartmentalised, 3D architecture of the nucleus and its role in adaptive responses. We moreover aim at uncovering how deregulated circadian genome organization contributes to complex diseases, such as cancer and endocrine-metabolic diseases.

Articles

Article: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 2024;43(1):107
A phenotypic screening approach to target p60AmotL2-expressing invasive cancer cells
Fonseca P; Cui W; Struyf N; Tong L; Chaurasiya A; Casagrande F; Zhao H; Fernando D; Chen X; Tobin NP; Seashore-Ludlow B; Lundqvist A; Hartman J; Gondor A; Ostling P; Holmgren L
Article: NATURE PROTOCOLS. 2023;18(3):755-782
The Nodewalk assay to quantitate chromatin fiber interactomes in very small cell populations
Vestlund J; Sumida N; Mehmood R; Bhartiya D; Wu S; Gondor A
Article: NATURE COMMUNICATIONS. 2022;13(1):204
Canonical WNT signaling-dependent gating of MYC requires a noncanonical CTCF function at a distal binding site
Chachoua I; Tzelepis I; Dai H; Lim JP; Lewandowska-Ronnegren A; Casagrande FB; Wu S; Vestlund J; de Lima CDM; Bhartiya D; Scholz BA; Martino M; Mehmood R; Gondor A
Article: NUCLEIC ACIDS RESEARCH. 2020;48(19):10867-10876
MYC as a driver of stochastic chromatin networks: implications for the fitness of cancer cells
Sumida N; Sifakis EG; Kiani NA; Ronnegren AL; Scholz BA; Vestlund J; Gomez-Cabrero D; Tegner J; Gondor A; Ohlsson R
Article: MOLECULAR & CELLULAR ONCOLOGY. 2020;7(2):1710992
WNT-mediated gene gating: a novel principle connecting oncogenic super-enhancers with the nuclear pore to drive pathological expression of MYC
Gondor A
Article: NATURE GENETICS. 2019;51(12):1723-1731
WNT signaling and AHCTF1 promote oncogenic MYC expression through super-enhancer-mediated gene gating
Scholz BA; Sumida N; de Lima CDM; Chachoua I; Martino M; Tzelepis I; Nikoshkov A; Zhao H; Mehmood R; Sifakis EG; Bhartiya D; Gondor A; Ohlsson R
Article: FRONTIERS IN PHARMACOLOGY. 2017;8:726
Phenotypic Screen Identifies a Small Molecule Modulating ERK2 and Promoting Stem Cell Proliferation
Yin C; Fufa T; Chandrasekar G; Aeluri M; Zaky V; Abdelhady S; Rodriguez AB; Jakobsson J; Varnoosfaderani FS; Mahalingam J; Liu J; Larsson O; Hovatta O; Gaunitz F; Gondor A; Andang M; Kitambi SS
Article: MOLECULAR CELL. 2015;59(6):984-997
PARP1-and CTCF-Mediated Interactions between Active and Repressed Chromatin at the Lamina Promote Oscillating Transcription
Zhao H; Sifakis EG; Sumida N; Millan-Arino L; Scholz BA; Svensson JP; Chen X; Ronnegren AL; de Lima CDM; Varnoosfaderani FS; Shi C; Loseva O; Yammine S; Israelsson M; Rathje L-S; Nemeti B; Fredlund E; Helleday T; Imreh MP; Gondor A
Article: EPIGENETICS. 2014;9(11):1439-1445
The visualization of large organized chromatin domains enriched in the H3K9me2 mark within a single chromosome in a single cell
Chen X; Yammine S; Shi C; Tark-Dame M; Gondor A; Ohlsson R
Article: BIOTECHNIQUES. 2014;56(3):117-124
Chromatin in situ proximity (ChrISP): Single-cell analysis of chromatin proximities at a high resolution
Chen X; Shi C; Yammine S; Gondor A; Ronnlund D; Fernandez-Woodbridge A; Sumida N; Widengren J; Ohlsson R
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2012;41(6):1959-1966
Cell type and context-specific function of PLAG1 for IGF2 P3 promoter activity
Akhtar M; Holmgren C; Gondor A; Vesterlund M; Kanduri C; Larsson C; Ekstrom TJ
Article: EPIGENETICS. 2012;7(4):361-369
CTCF-binding sites within the H19 ICR differentially regulate local chromatin structures and cis-acting functions
Guibert S; Zhao Z; Sjolinder M; Gondor A; Fernandez A; Pant V; Ohlsson R
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(23):17310-17317
A Novel Intronic Peroxisome Proliferator-activated Receptor γ Enhancer in the Uncoupling Protein (UCP) 3 Gene as a Regulator of Both UCP2 and-3 Expression in Adipocytes
Bugge A; Siersbaek M; Madsen MS; Gondor A; Rougier C; Mandrup S
Article: COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY. 2010;75:493-500
Window into the Complexities of Chromosome Interactomes
Gondor A; Woodbridge AF; Shi C; Aurell E; Imreh M; Ohlsson R
Article: GENES & DEVELOPMENT. 2009;23(22):2598-2603
Nonallelic transvection of multiple imprinted loci is organized by the H19 imprinting control region during germline development
Sandhu KS; Shi C; Sjolinder M; Zhao Z; Gondor A; Liu L; Tiwari VK; Guibert S; Emilsson L; Imreh MP; Ohlsson R
Article: EMBO REPORTS. 2008;9(4):327-329
Chromatin insulators and cohesins
Goendoer A; Ohlsson R
Article: NATURE PROTOCOLS. 2008;3(2):303-313
High-resolution circular chromosome conformation capture assay
Gondor A; Rougier C; Ohlsson R
Article: CURRENT OPINION IN CELL BIOLOGY. 2007;19(3):321-325
The 4C technique:: the 'Rosetta stone' for genome biology in 3D?
Ohlsson R; Gondor A
Article: NATURE GENETICS. 2006;38(11):1341-1347
Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions
Zhao Z; Tavoosidana G; Sjolinder M; Gondor A; Mariano P; Wang S; Kanduri C; Lezcano M; Sandhu KS; Singh U; Pant V; Tiwari V; Kurukuti S; Ohlsson R
Article: INTERNATIONAL JOURNAL OF CANCER. 2006;119(3):571-578
Identification of limited regions of genetic aberrations in patients affected with Wilms' tumor using a tiling-path chromosome 22 array.
Benetkiewicz M; Díaz de Ståhl T; Gördör A; Pfeifer S; Wittmann S; Gessler M; Dumanski JP
Article: MOLECULAR AND CELLULAR BIOLOGY. 2004;24(18):7855-7862
An antisense RNA regulates the bidirectional silencing property of the Kcnq1 imprinting control region
Thakur N; Tiwari VK; Thomassin H; Pandey RR; Göndör A; Grange T; Ohlsson R; Kanduri C
Journal article: EUROPEAN JOURNAL OF CANCER. 2001;37:s123
The apoptotic effect of TGF-beta in human lymphoma cells
Sebestyen A; Barna G; Gondor A; Nagy K; Weishede S; Bauer P; Kopper L
Article: ANTICANCER RESEARCH. 2001;21(2A):1207-1212
TGFβ1 induces caspase-dependent but death-receptor independent apoptosis in lymphoid cells
Tótth A; Sebestyén A; Barna G; Nagy K; Göndör A; Bocsi J; Mihalik R; Peták I; Houghton J; Kopper L
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All other publications

Corrigendum: NATURE GENETICS. 2020;52(11):1265
WNT signaling and AHCTF1 promote oncogenic MYC expression through super-enhancer-mediated gene gating (vol 51, pg 1723, 2019)
Scholz BA; Sumida N; de Lima CDM; Chachoua I; Martino M; Tzelepis I; Nikoshkov A; Zhao H; Mehmood R; Sifakis EG; Bhartiya D; Gondor A; Ohlsson R
Preprint: BIORXIV. 2018
The ultra-sensitive Nodewalk technique identifies stochastic from virtual, population-based enhancer hubs regulatingMYCin 3D: Implications for the fitness of cancer cells
Sumida N; Sifakis E; Scholz B; Fernandez-Woodbridge A; Kiani N; Gomez-Cabrero D; Svensson P; Tegner J; Göndör A; Ohlsson R
Editorial comment: SCIENCE. 2018;359(6381):1212-1213
Circadian organization of the genome
de Lima CDM; Gondor A
Review: F1000RESEARCH. 2018;7:F1000 Faculty Rev-681-681
Enhancer functions in three dimensions: beyond the flat world perspective.
Göndör A; Ohlsson R
Book chapter: CHROMATIN REGULATION AND DYNAMICS. 2017;p. 1-34
Chapter 1 A Brief Introduction to Chromatin Regulation and Dynamics
Tzelepis I; Martino M; Göndör A
Book chapter: CHROMATIN REGULATION AND DYNAMICS. 2017;p. xxi-xxii
Preface
Göndör A
Book chapter: CHROMATIN REGULATION AND DYNAMICS. 2017;p. 417-460
Chapter 17 3D Nuclear Architecture and Epigenetic Memories: Regulators of Phenotypic Plasticity in Development, Aging and Cancer
Scholz BA; Millán-Ariño L; Göndör A
Review: NATURE REVIEWS GENETICS. 2016;17(5):284-299
Epigenetic modulators, modifiers and mediators in cancer aetiology and progression
Feinberg AP; Koldobskiy MA; Gondor A
Conference publication: CHROMOSOME RESEARCH. 2015;23(2):359-360
H3K9 methylation fine-tunes coordination of transcription by regulating chromatin conformation plasticity
Chen X; Yammine S; Sumida N; Fernandez-Woodbridge A; Shi C; Shahin F; Tark-Dame ML; Imreh MP; Gondor A; Ohlsson R
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2013;23(2):63-64
Nuclear architecture and chromatin structure on the path to cancer
Gondor A
Review: SEMINARS IN CANCER BIOLOGY. 2013;23(2):90-98
Dynamic chromatin loops bridge health and disease in the nuclear landscape
Gondor A
Review: NATURE. 2009;461(7261):212-217
Chromosome crosstalk in three dimensions
Gondor A; Ohlsson R
Review: NATURE REVIEWS GENETICS. 2009;10(4):269-276
OPINION Replication timing and epigenetic reprogramming of gene expression: a two-way relationship?
Gondor A; Ohlsson R
Editorial comment: BRITISH JOURNAL OF SURGERY. 2008;95(8):939-940
Epigenetic regulation
Gondor A
Editorial comment: NATURE GENETICS. 2006;38(11):1229-1230
Transcription in the loop
Gondor A; Ohlsson R
Review: LAKARTIDNINGEN. 2006;103(12):919-925
[Epigenetics--cellular memories--affect disease development].
Ohlsson R; Göndor A

Grants

Interaction between sex steroids, physical exercise and metabolism in female reproduction and health
Swedish Research Council
1 January 2025 - 31 December 2029
Göndör, Anita Katalin – Circadian gene trafficking: A novel mechanism of oncogene regulation in cancer
Swedish Cancer Society
1 January 2024
A new paradigm in cancer evolution: Circadian 3D regulation of oncogene gating
Norwegian Cancer Society
1 May 2023 - 30 April 2027
Circadian dysregulation of the 3D epigenome as a platform for adaptive plasticity in childhood cancer
Barncancerfonden
1 January 2023 - 31 December 2023
Circadian gene trafficking: A new paradigm in cancer evolution
Swedish Research Council
1 January 2022 - 31 December 2025
Interaction between sex steroids, physical exercise and metabolism in female reproduction and health
Swedish Research Council
1 January 2022 - 31 December 2024
Göndör, Anita Katalin – Cancer cell-specific circadian gene trafficking: A new angle on an old problem
Swedish Cancer Society
1 January 2022
Enhancer-mediated gating of pluripotency genes: A new principle of regulation of expression driving cancer progression
Swedish Research Council
1 January 2020 - 31 December 2023
Perturbed circadian epigenome organization: a novel therapeutic target to eliminate cancer stem-like cell states
Swedish Cancer Society
1 January 2020
Perturbed circadian epigenome organization: a novel therapeutic target to eliminate cancer stem-like cell states
Swedish Cancer Society
1 January 2019
The 3D organization of the hereditary mass collaborates with circadian gene regulation: New perspectives on the cancer process
Swedish Cancer Society
1 January 2018
Innovations of techniques for the single cell analysis of dynamic chromatin structures
Swedish Research Council
1 January 2018 - 31 December 2018
Interaction between sex steroids, physical activity and metabolism in female reproduction and health
Swedish Research Council
1 January 2018 - 31 December 2021
The Achilles’ heel of breast cancer
Knut and Alice Wallenberg Foundation
1 January 2017 - 1 January 2022
The 3D organization of the hereditary mass collaborates with circadian gene regulation: New perspectives on the cancer process
Swedish Cancer Society
1 January 2017
The 3D organization of the hereditary mass collaborates with circadian gene regulation: New perspectives on the cancer process
Swedish Cancer Society
1 January 2016
Interplay between 3D genome organization and the circadian oscillator: implications for human diseases
Swedish Research Council
1 January 2016 - 31 December 2019
The DNA damage response machinery establish/manifest chromosome interactomes to influence the expressivity of the human genome in development and disease
Swedish Research Council
1 January 2012 - 31 December 2014
Chromatin crosstalk: Regulation of expressivity of the genome in 3 dimensions
Swedish Research Council
1 January 2010 - 31 December 2012
Web of chromosomal interactions: New paradigm of disease mechanism
Swedish Research Council
1 January 2009 - 31 December 2011

Employments

Principal Researcher, Department of Oncology-Pathology, Karolinska Institutet, 2022-

Degrees and Education

Docent, Karolinska Institutet, 2020

About me

Research

Articles

All other publications

Grants

Employments

Degrees and Education

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