Top Publications MTC

Top Publications by MTC Researchers.

Top Publications 2020

Visualization of human T lymphocyte-mediated eradication of cancer cells in vivo.
He X, Yin X, Wu J, Wickström SL, Duo Y, Du Q, et al
Proc Natl Acad Sci U S A 2020

Therapeutic paradigm of dual targeting VEGF and PDGF for effectively treating FGF-2 off-target tumors.
Hosaka K, Yang Y, Seki T, Du Q, Jing X, He X, et al
Nat Commun 2020 

An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction.
Hanke L, Vidakovics Perez L, Sheward DJ, Das H, Schulte T, Moliner-Morro A, et al
Nat Commun 2020

GPR43 regulates marginal zone B-cell responses to foreign and endogenous antigens.
Rohrbeck L, Adori M, Wang S, He C, Tibbitt CA, Chernyshev M, et al
Immunol Cell Biol 2020

Sensitivity of Alphaviruses to G3BP Deletion Correlates with Efficiency of Replicase Polyprotein Processing.
Götte B, Utt A, Fragkoudis R, Merits A, McInerney GM
J Virol 2020

Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2.
Mushtaq M, Kovalevska L, Darekar S, Abramsson A, Zetterberg H, Kashuba V, et al
Proc Natl Acad Sci U S A 2020 

p53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids.
Marin Navarro A, Pronk RJ, van der Geest AT, Oliynyk G, Nordgren A, Arsenian-Henriksson M, et al
Cell Death Dis 2020

Successful delivery of large-size CRISPR/Cas9 vectors in hard-to-transfect human cells using small plasmids.
Søndergaard JN, Geng K, Sommerauer C, Atanasoai I, Yin X, Kutter C
Commun Biol 2020

TIF-Seq2 disentangles overlapping isoforms in complex human transcriptomes.
Wang J, Li B, Marques S, Steinmetz LM, Wei W, Pelechano V
Nucleic Acids Res 2020

Mannose receptor-derived peptides neutralize pore-forming toxins and reduce inflammation and development of pneumococcal disease.
Subramanian K, Iovino F, Tsikourkitoudi V, Merkl P, Ahmed S, Berry SB, et al
EMBO Mol Med 2020

Silica-coated phosphorescent nanoprobes for selective cell targeting and dynamic bioimaging of pathogen-host cell interactions.
Iovino F, Merkl P, Spyrogianni A, Henriques-Normark B, Sotiriou GA
Chem Commun (Camb) 2020

Grad-seq in a Gram-positive bacterium reveals exonucleolytic sRNA activation in competence control.
Hör J, Garriss G, Di Giorgio S, Hack LM, Vanselow JT, Förstner KU, et al
EMBO J 2020

The impact of the ancillary pilus-1 protein RrgA of Streptococcus pneumoniae on colonization and disease.
Iovino F, Nannapaneni P, Henriques-Normark B, Normark S
Mol Microbiol 2020 

Integrative discovery of treatments for high-risk neuroblastoma.
Almstedt E, Elgendy R, Hekmati N, Rosén E, Wärn C, Olsen TK, et al
Nat Commun 2020 

Top Publications 2019

A mass spectrometry-based approach to distinguish annular and specific lipid binding to membrane proteins.
Bolla JR, Corey RA, Sahin C, Gault J, Hummer A, Hopper JTS, et al
Angew. Chem. Int. Ed. Engl. 2019 

Safety of proton pump inhibitors questioned based on a large randomized trial of patients receiving rivaroxaban or aspirin.
Simin J, Liu Q, Fornes R, Brusselaers N
Gastroenterology 2019 

An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Zhang L, Irimia A, He L, Landais E, Rantalainen K, Leaman DP, et al
Nat Commun 2019 

Pair Correlation Analysis Maps the Dynamic Two-Dimensional Organization of Natural Killer Cell Receptors at the Synapse.
Hedde PN, Staaf E, Singh SB, Johansson S, Gratton E
ACS Nano 2019 

Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.
Wei W, Hennig BP, Wang J, Zhang Y, Piazza I, Pareja Sanchez Y, et al
Genome Res. 2019

Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability.
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, et al
Immunity 2019

Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses.
Phad GE, Pushparaj P, Tran K, Dubrovskaya V, Àdori M, Martinez-Murillo P, et al
J. Exp. Med. 2019

Evolutionary analyses of base-pairing interactions in DNA and RNA secondary structures.
Golden M, Murrell B, Martin D, Pybus OG, Hein J
Mol. Biol. Evol. 2019

Microbe-host interplay in atopic dermatitis and psoriasis.
Fyhrquist N, Muirhead G, Prast-Nielsen S, Jeanmougin M, Olah P, Skoog T, et al
Nat Commun 2019

The Prevotella copri Complex Comprises Four Distinct Clades Underrepresented in Westernized Populations.
Tett A, Huang KD, Asnicar F, Fehlner-Peach H, Pasolli E, Karcher N, et al
Cell Host Microbe 2019

No distinct microbiome signature of irritable bowel syndrome found in a Swedish random population.
Hugerth LW, Andreasson A, Talley NJ, Forsberg AM, Kjellström L, Schmidt PT, et al
Gut 2019

HyPhy 2.5 - a customizable platform for evolutionary hypothesis testing using phylogenies.
Kosakovsky Pond SL, Poon AFY, Velazquez R, Weaver S, Hepler NL, Murrell B, et al
Mol. Biol. Evol. 2019

Long-read amplicon denoising.
Kumar V, Vollbrecht T, Chernyshev M, Mohan S, Hanst B, Bavafa N, et al
Nucleic Acids Res. 2019

Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk.
Tengvall K, Huang J, Hellström C, Kammer P, Biström M, Ayoglu B, et al
Proc. Natl. Acad. Sci. U.S.A. 2019

EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance.
Li S, Rodriguez J, Li W, Bullova P, Fell SM, Surova O, et al
Proc. Natl. Acad. Sci. U.S.A. 2019

Ultrabright and Stable Luminescent Labels for Correlative Cathodoluminescence Electron Microscopy Bioimaging.
Keevend K, Puust L, Kurvits K, Gerken LRH, Starsich FHL, Li JH, et al
Nano Lett. 2019

Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, et al
Cell 2019

How to lose tumor suppression
David Philip Lane
Science 365 (6453), 539-540 2019

EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance.
Li S, Rodriguez J, Li W, Bullova P, Fell SM, Surova O, et al
Proc. Natl. Acad. Sci. U.S.A. 2019 

Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy.
Uribesalgo I, Hoffmann D, Zhang Y, Kavirayani A, Lazovic J, Berta J, et al
EMBO Mol Med 2019

The gut microbiota influences skeletal muscle mass and function in mice.
Lahiri S, Kim H, Garcia-Perez I, Reza MM, Martin KA, Kundu P, et al
Sci Transl Med 2019 

Adipocyte and lipid metabolism in cancer drug resistance.
Cao Y
J. Clin. Invest. 2019 

Single-Cell RNA Sequencing of the T Helper Cell Response to House Dust Mites Defines a Distinct Gene Expression Signature in Airway Th2 Cells.
Tibbitt CA, Stark JM, Martens L, Ma J, Mold JE, Deswarte K, et al
Immunity 2019

Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery.
Götte B, Panas MD, Hellström K, Liu L, Samreen B, Larsson O, et al
PLoS Pathog. 2019

Spatial and temporal localization of immune transcripts defines hallmarks and diversity in the tuberculosis granuloma. Berit Carow, Thomas Hauling, Xiaoyan Qian, Igor Kramnik, Mats Nilsson & Martin E. Rottenberg. Nature Communications volume 10, Article number: 1823 (2019)

Accumulation of Circulating CCR7+ Natural Killer Cells Marks Melanoma Evolution and Reveals a CCL19-Dependent Metastatic Pathway.
Cristiani CM, Turdo A, Ventura V, Apuzzo T, Capone M, Madonna G, et al
Cancer Immunol Res 2019 

Luminescent CeO2:Eu3+ nanocrystals for robust in situ H2O2 real-time detection in bacterial cell cultures.
Henning DF, Merkl P, Yun C, Iovino F, Xie L, Mouzourakis E, et al
Biosens Bioelectron 2019 

FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis.
Turunen SP, von Nandelstadh P, Öhman T, Gucciardo E, Seashore-Ludlow B, Martins B, et al
Cell Death Differ. 2019 

System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection.
Garcia-Moreno M, Noerenberg M, Ni S, Järvelin AI, González-Almela E, Lenz CE, et al
Mol. Cell 2019 

Multi-faceted inhibition of dendritic cell function by CD4+Foxp3+ regulatory T cells.
Seitz C, Liu S, Klocke K, Joly AL, Czarnewski PV, Tibbitt CA, et al
J. Autoimmun. 2019

Integrated Molecular Analysis of Undifferentiated Uterine Sarcomas Reveals Clinically Relevant Molecular Subtypes.
Binzer-Panchal A, Hardell E, Viklund B, Ghaderi M, Bosse T, Nucci MR, et al
Clin. Cancer Res. 2019 

Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival.
Subramanian K, Neill DR, Malak HA, Spelmink L, Khandaker S, Dalla Libera Marchiori G, et al
Nat Microbiol 2019
 

CXADR-Mediated Formation of an AKT Inhibitory Signalosome at Tight Junctions Controls Epithelial-Mesenchymal Plasticity in Breast Cancer.
Nilchian A, Johansson J, Ghalali A, Asanin ST, Santiago A, Rosencrantz O, et al
Cancer Res. 2019