Top Publications 2018
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Nat Commun 2018 03;9(1):1107
ΔNp73 enhances HIF-1α protein stability through repression of the ECV complex.
Oncogene 2018 Apr;():
CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis.
J. Clin. Invest. 2018 Mar;128(3):1106-1124
STAT3 expression by myeloid cells is detrimental for the T- cell-mediated control of infection with Mycobacterium tuberculosis.
PLoS Pathog. 2018 Jan;14(1):e1006809
Stand-alone ClpG disaggregase confers superior heat tolerance to bacteria.
Proc. Natl. Acad. Sci. U.S.A. 2018 Jan;115(2):E273-E282
Mechanisms regulating expansion of CD8+ T cells during HIV-1 infection.
J. Intern. Med. 2018 Mar;283(3):257-267
Lipids Shape the Electron Acceptor-Binding Site of the Peripheral Membrane Protein Dihydroorotate Dehydrogenase.
Cell Chem Biol 2018 Mar;25(3):309-317.e4
Ablation of endothelial VEGFR1 improves metabolic dysfunction by inducing adipose tissue browning.
J. Exp. Med. 2018 Feb;215(2):611-626
Flt3 ligand expands bona fide innate lymphoid cell precursors in vivo.
Sci Rep 2018 Jan;8(1):154
Alphavirus-induced hyperactivation of PI3K/AKT directs pro-viral metabolic changes.
PLoS Pathog. 2018 Jan;14(1):e1006835
-amplified neuroblastoma maintains an aggressive and undifferentiated phenotype by deregulation of estrogen and NGF signaling.
Proc. Natl. Acad. Sci. U.S.A. 2018 Feb;115(6):E1229-E1238
Novel concept of the smart NIR-light-controlled drug release of black phosphorus nanostructure for cancer therapy.
Proc. Natl. Acad. Sci. U.S.A. 2018 Jan;115(3):501-506
Monoclonal Antibodies against Specific p53 Hotspot Mutants as Potential Tools for Precision Medicine.
Cell Rep 2018 Jan;22(1):299-312