Publications- Yihai Cao group

Selected publications

Selected 10 original research articles

Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance.
Iwamoto H, Abe M, Yang Y, Cui D, Seki T, Nakamura M, et al
Cell Metab. 2018 Jul;28(1):104-117.e5

Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.
Martinez Molina D, Jafari R, Ignatushchenko M, Seki T, Larsson EA, Dan C, et al
Science 2013 Jul;341(6141):84-7

Cold exposure promotes atherosclerotic plaque growth and instability via UCP1-dependent lipolysis.
Dong M, Yang X, Lim S, Cao Z, Honek J, Lu H, et al
Cell Metab. 2013 Jul;18(1):118-29

PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells.
Xue Y, Lim S, Yang Y, Wang Z, Jensen LD, Hedlund EM, et al
Nat. Med. 2011 Dec;18(1):100-10

Hypoxia-independent angiogenesis in adipose tissues during cold acclimation.
Xue Y, Petrovic N, Cao R, Larsson O, Lim S, Chen S, et al
Cell Metab. 2009 Jan;9(1):99-109

PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis.
Cao R, Björndahl MA, Religa P, Clasper S, Garvin S, Galter D, et al
Cancer Cell 2004 Oct;6(4):333-45

Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2.
Cao R, Bråkenhielm E, Pawliuk R, Wariaro D, Post MJ, Wahlberg E, et al
Nat. Med. 2003 May;9(5):604-13

Placenta growth factor-1 antagonizes VEGF-induced angiogenesis and tumor growth by the formation of functionally inactive PlGF-1/VEGF heterodimers.
Eriksson A, Cao R, Pawliuk R, Berg SM, Tsang M, Zhou D, et al
Cancer Cell 2002 Feb;1(1):99-108

Angiogenesis inhibited by drinking tea.
Cao Y, Cao R
Nature 1999 Apr;398(6726):381

Spinal cord repair in adult paraplegic rats: partial restoration of hind limb function.
Cheng H, Cao Y, Olson L
Science 1996 Jul;273(5274):510-3

Selected 10 review articles

Adipocyte and lipid metabolism in cancer drug resistance.
Cao Y
J. Clin. Invest. 2019 07;129(8):3006-3017

Obesity Protects Cancer from Drugs Targeting Blood Vessels.
Cao Y
Cell Metab. 2018 06;27(6):1163-1165

VEGF-targeted cancer therapeutics-paradoxical effects in endocrine organs.
Cao Y
Nat Rev Endocrinol 2014 Sep;10(9):530-9

Angiogenesis and vascular functions in modulation of obesity, adipose metabolism, and insulin sensitivity.
Cao Y
Cell Metab. 2013 Oct;18(4):478-89

Forty-year journey of angiogenesis translational research.
Cao Y, Arbiser J, D'Amato RJ, D'Amore PA, Ingber DE, Kerbel R, et al
Sci Transl Med 2011 Dec;3(114):114rv3

Optimizing the delivery of cancer drugs that block angiogenesis.
Cao Y, Langer R
Sci Transl Med 2010 Jan;2(15):15ps3

Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases.
Cao Y
Nat Rev Drug Discov 2010 Feb;9(2):107-15

Off-tumor target--beneficial site for antiangiogenic cancer therapy?
Cao Y
Nat Rev Clin Oncol 2010 10;7(10):604-8

Positive and negative modulation of angiogenesis by VEGFR1 ligands.
Cao Y
Sci Signal 2009 Feb;2(59):re1

Opinion: emerging mechanisms of tumour lymphangiogenesis and lymphatic metastasis.
Cao Y
Nat. Rev. Cancer 2005 09;5(9):735-43