CTMR Bug Corner
Weekly, microbiome-focused seminars on Thursdays from 9:00 - 10:00!
Seminars are on Zoom or in-person (if you have access to Biomedicum). To get the Zoom link, information and reminders you need to be on the Bug Corner email distribution list (see below).
Spring 2024 Schedule
Affiliation: Nadja Patenge, Biologist, Researcher at the Institute for Medical Microbiology, Virology, and Hygiene, University Medicine Rostock.
My group is working on peptide nucleic acid (PNA) antisense technology. We are currently focusing on optimizing the antimicrobial effect of antisense PNAs on streptococci by improving bacterial PNA uptake and identifying suitable target sequences. Other important topics for us are off-target effects of PNA treatment on the bacterial transcriptome and the dynamics of resistance development in comparison to conventional antibiotics treatment.
Affiliation: Moritz Jansson, assistant physician, Researcher at the Institute for Medical Microbiology, Virology, and Hygiene, University Medicine Rostock.
My group investigates the potential of in vitro transcribed (IVT)-mRNA for the use of actively combating bacterial infections. With nature providing us with an exhaustless array of peptide and protein based antibacterial molecules mRNA platforms have the potential to deliver the “building instructions” of these molecules to human cells to fight bacterial pathogens. So far our work has been focused on a proof of concept study using mRNA-encoded bacteriophage endolysins with activity against Streptococcus pneumoniae in an in vitro model.
Dr. Emily Vogtmann is an Earl Stadtman Investigator in the Metabolic Epidemiology Branch of the Division of Cancer Epidemiology & Genetics in the National Cancer Institute. She received her B.S. in biochemistry and molecular biology and B.A. in Spanish from Michigan State University, M.P.H. in international health epidemiology from the University of Michigan, and Ph.D. in epidemiology in 2013 from the University of Alabama at Birmingham. Dr. Vogtmann’s research focuses on the association between the human microbiome and cancer risk and the evaluation of methods for collection, storage, and processing of samples and data for study of the human microbiome