Division of Immunology

We focus on two main areas of research: Primary immunodeficiency and B cell malignancy. Pan Hammarström Lab aim to conduct four projects:

Regulation of immunoglobulin class switch recombination in human B cells

Induced pluripotent stems cells a platform for personalized diagnosis and therapy in patients with primary immunodeficiency

Discovery of therapeutic targets in B cell lymphoma by next generation sequencing

Antibody therapy against COVID-19

Our research group, led by Rikard Holmdahl, aims to understand the basic pathogenic mechanisms behind autoimmune diseases and cancer. We try to identify and functionally analyse the genes that control autoimmune diseases, primarily by using animal models in which it is possible to identify genetic causes of complex diseases.
With this knowledge we develop new diagnostics and vaccines for the treatment of autoimmune diseases like rheumatoid arthritis, and aim to improve immunotherapy in cancer.

The Department of Medical Biochemistry and Biophysics (MBB) performs basic research and higher education. The aim with our research is to understand fundamental cellular processes and their role in disease.