About Research Division of Genome Biology
The research conducted at the Research Division of Genome Biology explores various aspects of genome metabolism, and how their perturbation can lead to disease. Besides our basic research activities, and with the help of the national platforms available at Karolinska campus, we also investigate in translational aspects that can derive in new treatments for various diseases.
Research interests
At the Division of Genome Biology at Karolinska Institutet and SciLifeLab, we explore how the genome shapes life — from DNA repair and chromatin regulation to cell division and drug discovery. Our scientists combine molecular biology, advanced imaging, synthetic biology and chemistry, and data science to uncover how genome maintenance and organization influence health and disease.
RESEARCH GROUPS
Andreas Luttens Group
Combines AI, chemistry, and structural biology to accelerate drug discovery.
Bennie Lemmens Group
Investigates how human cells maintain, copy and propagate DNA.
Jan Ellenberg Group
Explore molecular mechanisms that drive early embryonic division and nuclear organization.
Jiri Bartek Group
Studies how cells detect and repair DNA damage to preserve genome stability and identify new therapeutic targets in cancer.
Oscar Fernández-Capetillo Group
Exploiting cell-based phenotypic screens to discover molecules that modulate stress responses and disease pathways.
Simon Elsässer Group
Develops chemical and synthetic biology tools to reveal how chromatin structure controls gene expression.