Structure of TrxR1.

Laboratory for protein misfolding and assembly

We work on the behavior of proteins under physiological and pathological conditions. One focus is to understand what makes certain proteins misfold and aggregate into amyloids in association with severe human diseases and to find ways to counteract these phenomena as an approach to treat neurodegenerative diseases, in particular Alzheimer´s, lung disease and cancer. We also want to understand the underlying molecular mechanisms to create biotechnological tools and novel biomaterials.

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