Virginia Stone

Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(1):141.13

Characterization of immune response towards modified Coxsackie B virus-like particle vaccine in a murine model

Soppela SM; Gonzalez-Rodriguez M; Stone V; Kummola L; Lampinen V; Jouppila N; Laitinen O; Flodstrom-Tullberg M; Junttila I; Hankaniemi M

Article: ISCIENCE. 2022;25(10):105070

Coxsackievirus B infections are common in Cystic Fibrosis and experimental evidence supports protection by vaccination

Stone VM; Utorova R; Butrym M; Sioofy-Khojine A-B; Hankaniemi MM; Ringqvist EE; Blanter M; Parajuli A; Pincikova T; Fischler B; Karpati F; Hytonen VP; Hyoty H; Hjelte L; Flodstrom-Tullberg M

Article: FRONTIERS IN ENDOCRINOLOGY. 2022;13:971313

Proteome profiling of whole plasma and plasma-derived extracellular vesicles facilitates the detection of tissue biomarkers in the non-obese diabetic mouse

Lozano IMD; Sork H; Stone VM; Eldh M; Cao X; Pernemalm M; Gabrielsson S; Flodstrom-Tullberg M

Article: DIABETES. 2021;70(12):2871-2878

Coxsackievirus B Vaccines Prevent Infection-Accelerated Diabetes in NOD Mice and Have No Disease-Inducing Effect

Stone VM; Butrym M; Hankaniemi MM; Sioofy-Khojine A-B; Hytonen VP; Hyoty H; Flodstrom-Tullberg M

Article: MICROORGANISMS. 2021;9(1):E105-105

Inhibition of Type III Interferon Expression in Intestinal Epithelial Cells-A Strategy Used by Coxsackie B Virus to Evade the Host's Innate Immune Response at the Primary Site of Infection?

Stone VM; Ringqvist EE; Larsson PG; Domsgen E; Holmlund U; Sverremark-Ekstrom E; Flodstrom-Tullberg M

Article: MICROORGANISMS. 2020;8(9):E1287-1287

Structural Insight into CVB3-VLP Non-Adjuvanted Vaccine

Hankaniemi MM; Baikoghli MA; Stone VM; Xing L; Vaatainen O; Soppela S; Sioofy-Khojine A; Saarinen NVV; Ou T; Anson B; Hyoty H; Marjomaki V; Flodstrom-Tullberg M; Cheng RH; Hytonen VP; Laitinen OH

Article: SCIENCE ADVANCES. 2020;6(19):eaaz2433

A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates

Stone VM; Hankaniemi MM; Laitinen OH; Sioofy-Khojine AB; Lin A; Lozano IMD; Mazur MA; Marjomaki V; Lore K; Hyoty H; Hytonen VP; Flodstrom-Tullberg M

Article: VIRUSES-BASEL. 2020;12(1):E78-78

Antibody Responses against Enterovirus Proteases are Potential Markers for an Acute Infection

Saarinen NVV; Stone VM; Hankaniemi MM; Mazur MA; Vuorinen T; Flodstrom-Tullberg M; Hyoty H; Hytonen VP; Laitinen OH

Article: ANTIVIRAL RESEARCH. 2019;171:104595

Formalin treatment increases the stability and immunogenicity of coxsackievirus B1 VLP vaccine

Hankaniemi MM; Stone VM; Andrejeff T; Heinimaki S; Sioofy-Khojine A-B; Marjomaki V; Hyoty H; Blazevic V; Flodstrom-Tullberg M; Hytonen VP; Laitinen OH

Article: VACCINE. 2019;37(40):5962-5971

A comparative study of the effect of UV and formalin inactivation on the stability and immunogenicity of a Coxsackievirus B1 vaccine

Hankaniemi MM; Stone VM; Sioofy-Khojine A-B; Heinimaki S; Marjomaki V; Hyoty H; Blazevic V; Laitinen IH; Flodstrom-Tullberg M; Hytonen VP

Article: SCIENTIFIC REPORTS. 2019;9(1):11244

Short-term CFTR inhibition reduces islet area in C57BL/6 mice

Khan D; Kelsey R; Maheshwari RR; Stone VM; Hasib A; Koivula FNM; Watson A; Harkin S; Irwin N; Shaw JA; McClenaghan NH; Venglovecz V; Ebert A; Flodstrom-Tullberg M; White MG; Kelly C

Article: JOURNAL OF VIROLOGICAL METHODS. 2018;255:29-37

New Coxsackievirus 2A^pro and 3C^pro protease antibodies for virus detection and discovery of pathogenic mechanisms

Laitinen OH; Svedin E; Kapell S; Hankaniemi MM; Larsson PG; Domsgen E; Stone VM; Maatta JAE; Hyoty H; Hytonen VP; Flodstrom-Tullberg M

Article: DIABETOLOGIA. 2018;61(2):476-481

A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes

Stone VM; Hankaniemi MM; Svedin E; Sioofy-Khojine A; Oikarinen S; Hyoty H; Laitinen OH; Hytonen VP; Flodstrom-Tullberg M

Article: SCIENTIFIC REPORTS. 2018;8(1):33

A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses

Saarinen NVV; Laiho JE; Richardson SJ; Zeissler M; Stone VM; Marjomaki V; Kantoluoto T; Horwitz MS; Sioofy-Khojine A; Honkimaa A; Hankaniemi MM; Flodstrom-Tullberg M; Hyoty H; Hytonen VP; Laitinen OH

Article: JOURNAL OF INFECTIOUS DISEASES. 2017;216(10):1308-1317

A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defense

Svedin E; Utorova R; Huhn MH; Larsson PG; Stone VM; Garimella M; Lind K; Hagglof T; Pincikova T; Laitinen OH; McInerney GM; Scholte B; Hjelte L; Karlsson MCI; Flodstrom-Tullberg M

Article: VACCINE. 2017;35(30):3718-3725

Optimized production and purification of Coxsackievirus B1 vaccine and its preclinical evaluation in a mouse model

Hankaniemi MM; Laitinen OH; Stone VM; Sioofy-Khojine A; Maatta JAE; Larsson PG; Marjomaki V; Hyoty H; Flodstrom-Tullberg M; Hytonen VP

Article: JOURNAL OF CLINICAL VIROLOGY. 2015;69:165-171

Application of bioinformatics in probe design enables detection of enteroviruses on different taxonomic levels by advanced in situ hybridization technology

Laiho JE; Oikarinen S; Oikarinen M; Larsson PG; Stone VM; Hober D; Oberste S; Flodstrom-Tullberg M; Isola J; Hyoty H

Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2014;177(3):687-695

Type III interferons are expressed by Coxsackievirus-infected human primary hepatocytes and regulate hepatocyte permissiveness to infection

Lind K; Svedin E; Utorova R; Stone VM; Flodstrom-Tullberg M

Article: DIABETOLOGIA. 2014;57(6):1182-1191

GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans

Stone VM; Dhayal S; Brocklehurst KJ; Lenaghan C; Winzell MS; Hammar M; Xu X; Smith DM; Morgan NG

Article: PLOS ONE. 2014;9(12):e114942

The Beneficial Effects of n-3 Polyunsaturated Fatty Acids on Diet Induced Obesity and Impaired Glucose Control Do Not Require Gpr120

Bjursell M; Xu X; Admyre T; Bottcher G; Lundin S; Nilsson R; Stone VM; Morgan NG; Lam YY; Storlien LH; Linden D; Smith DM; Bohlooly-Y M; Oscarsson J

Article: BRITISH JOURNAL OF PHARMACOLOGY. 2012;165(8):2758-2770

The cytoprotective effects of oleoylethanolamide in insulin-secreting cells do not require activation of GPR119

Stone VM; Dhayal S; Smith DM; Lenaghan C; Brocklehurst KJ; Morgan NG

Journal article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2010;81(11):e60

POMD11 Cannabinoids are neuroprotective in a human cell culture model of Parkinson's disease

Carroll C; Zajicek JP; Hanemann CO; Stone V; Zeissler M

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