Valentyna Yasinska

Valentyna Yasinska

Postdoktorala Studier
Besöksadress: Alfred Nobels allé 8, plan 7, 14152 Huddinge
Postadress: H7 Medicin, Huddinge, H7 CIM Mjösberg, 171 77 Stockholm
Del av:

Artiklar

  • Journal article: EUROPEAN RESPIRATORY JOURNAL. 2025;:2501289
    Hansen S; von Bülow A; Cooper A; Sandin P; Ernstsson O; Kankaanranta H; Janson C; Lehtimäki L; Aarli BB; Geale K; Hjoberg J; Packham S; Sekulic D; Altraja A; Backman H; Karjalainen J; Sverrild A; Backer V; Kauppi P; Yasinska V; Porsbjerg C; Ulrik CS; Bossios A
  • Article: ALLERGY. 2025;80(9):2541-2556
    Wirth L; Weigel W; Stamper CT; Kolmert J; de Souza Ferreira S; Hammer Q; Sparreman Mikus M; Theorell J; Andersson L; Lantz A-S; Wallen-Nielsen E; Petren A; Wheelock CE; Bossios A; Lazarinis N; Malinovschi A; Janson C; Dahlen B; Hochdorfer T; Tibbitt CA; Dahlen S-E; Yasinska V; Mjosberg J
  • Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2025;13(7):1609-1619.e5
    von Bulow A; Hansen S; Sandin P; Cooper A; Ernstsson O; Geale K; Lehtimaki L; Ulrik C; Aarli BB; Ilmarinen P; Packham S; Hassan G; Sverrild A; Backman H; Karjalainen J; Backer V; Altraja A; Kauppi P; Yasinska V; Kilpelainen M; Viinanen A; Martin-Schmid J; Bossios A; Porsbjerg C; Kankaanranta H; Janson C
  • Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2025;155(4):1310-1320
    Alvarado-Vazquez PA; Mendez-Enriquez E; Salomonsson M; Kopac P; Koren A; Bidovec-Stojkovic U; Koren A; Bidovec-Stojkovic U; Skrgat S; Simonson OE; Yasinska V; Dahlen S-E; Pejler G; Janson C; Korosec P; Malinovschi A; Hallgren J
  • Journal article: EUROPEAN RESPIRATORY JOURNAL. 2025;65(3):2400691
    Khaleva E; Brightling C; Eiwegger T; Altraja A; Bégin P; Blumchen K; Bossios A; Bourdin A; Ten Brinke A; Brusselle G; Bumbacea RS; Bush A; Casale TB; Clarke GW; Chaudhuri R; Chung KF; Coleman C; Corren J; Dahlén S-E; Deschildre A; Djukanovic R; Eger K; Exley A; Fleming L; Fowler SJ; Gaillard EA; Gappa M; Gupta A; Haitchi HM; Hashimoto S; Heaney LG; Hedlin G; Henderson M; Hua W; Jackson DJ; Karadag B; Katelaris CH; Koh MS; Kopp MV; Koppelman GH; Kull I; Kurukulaaratchy RJ; Lee J-H; Mahler V; Mäkelä M; Masoli M; Mathioudakis AG; Mazon A; Melén E; Milger K; Moeller A; Murray CS; Nagakumar P; Nair P; Negus J; Nieto A; Papadopoulos NG; Paton J; Pijnenburg MW; Pike KC; Porsbjerg C; Rattu A; Rupani H; Rusconi F; Rutjes NW; Saglani S; Seddon P; Siddiqui S; Singer F; Tajiri T; Turner S; Upham JW; Vijverberg SJH; Wark PAB; Wechsler ME; Yasinska V; Roberts G
  • Article: EUROPEAN RESPIRATORY JOURNAL. 2025;65(3):2400691
    Khaleva E; Brightling C; Eiwegger T; Altraja A; Begin P; Blumchen K; Bossios A; Bourdin A; Ten Brinke A; Brusselle G; Bumbacea RS; Bush A; Casale TB; Clarke GW; Chaudhuri R; Chung KF; Coleman C; Corren J; Dahlen S-E; Deschildre A; Djukanovic R; Eger K; Exley A; Fleming L; Fowler SJ; Gaillard EA; Gappa M; Gupta A; Haitchi HM; Hashimoto S; Heaney LG; Hedlin G; Henderson M; Hua W; Jackson DJ; Karadag B; Katelaris CH; Koh MS; Kopp MV; Koppelman GH; Kull I; Kurukulaaratchy RJ; Lee J-H; Mahler V; Makela M; Masoli M; Mathioudakis AG; Mazon A; Melen E; Milger K; Moeller A; Murray CS; Nagakumar P; Nair P; Negus J; Nieto A; Papadopoulos NG; Paton J; Pijnenburg MW; Pike KC; Porsbjerg C; Rattu A; Rupani H; Rusconi F; Rutjes NW; Saglani S; Seddon P; Siddiqui S; Singer F; Tajiri T; Turner S; Upham JW; Vijverberg SJH; Wark PAB; Wechsler ME; Yasinska V; Roberts G
  • Article: EUROPEAN RESPIRATORY JOURNAL. 2024;64(5):2400207
    Kermani NZ; Chung KF; Macis G; Santini G; Clemeno FAA; Versi A; Sun K; Abdel-Aziz MI; Andersson LI; Auffray C; Badi Y; Bakke P; Brightling C; Brinkman P; Caruso M; Chanez P; De Meulder B; Djukanovic R; Fabbri L; Fowler SJ; Horvath I; Howarth P; James AJ; Kolmert J; Kraft M; Li C-X; Zee AHM-VD; Malerba M; Papi A; Rabe K; Sanak M; Shaw DE; Singh D; Mikus MS; van den Berge M; Wheelock AM; Wheelock CE; Yasinska V; Guo Y-K; Wagers S; Barnes PJ; Bush A; Sterk PJ; Dahlen S-E; Adcock IM; Siddiqui S; Montuschi P
  • Article: ERJ OPEN RESEARCH. 2023;9(5):00269-02023
    Yasinska V; Gomez C; Kolmert J; Ericsson M; Pohanka A; James A; Andersson LI; Sparreman-Mikus M; Sousa AR; Riley JH; Bates S; Bakke PS; Kermani NZ; Caruso M; Chanez P; Fowler SJ; Geiser T; Howarth PH; Horvath I; Krug N; Montuschi P; Sanak M; Behndig A; Shaw DE; Knowles RG; Dahlen B; Maitland-van der Zee A-H; Sterk PJ; Djukanovic R; Adcock IM; Chung KF; Wheelock CE; Dahlen S-E; Jonsson EW
  • Article: EUROPEAN RESPIRATORY JOURNAL. 2023;62(3):2202474
    von Bullow A; Hansen S; Sandin P; Ernstsson O; Janson C; Lehtimaeki L; Kankaanranta H; Ulrik C; Aarli BB; Geale K; Tang ST; Wolf M; Backer V; Hilberg O; Altraja A; Backman H; Ludviksdottir D; Bjornsdottir US; Kauppi P; Sandstrom T; Sverrild A; Yasinska V; Kilpelainen M; Dahlen B; Viinanen A; Bjermer L; Bossios A; Porsbjerg C
  • Article: ERJ OPEN RESEARCH. 2023;9(2):687-2022
    Hansen S; von Bulow A; Sandin P; Ernstsson O; Janson C; Lehtimaki L; Kankaanranta H; Ulrik C; Aarli BB; Wahl HF; Geale K; Tang ST; Wolf M; Larsen T; Altraja A; Backman H; Kilpelainen M; Viinanen A; Ludviksdottir D; Kauppi P; Sverrild A; Lehmann S; Backer V; Yasinska V; Skjold T; Karjalainen J; Bossios A; Porsbjerg C
  • Article: ERJ OPEN RESEARCH. 2022;8(2):65-2022
    Eger K; Paroczai D; Bacon A; Schleich F; Sergejeva S; Bourdin A; Vachier I; Zervas E; Katsoulis K; Papapetrou D; Kostikas K; Csoma Z; Heffler E; Canonica GW; Grisle I; Bieksiene K; Palacionyte J; Ten Brinke A; Hashimoto S; Smeenk FWJM; Braunstahl G-J; van der Sar S; Mihaltan F; Nenasheva N; Peredelskaya M; Zvezdin B; Cekerevac I; Hromis S; Cupurdija V; Lazic Z; Milenkovic B; Dimic-Janjic S; Yasinska V; Dahlen B; Bossios A; Lazarinis N; Aronsson D; Egesten A; Munir AKM; Ahlbeck L; Janson C; Skrgat S; Edelbaher N; Leuppi J; Jaun F; Rudiger J; Pavlov N; Gianella P; Fischer R; Charbonnier F; Chaudhuri R; Smith SJ; Doe S; Fawdon M; Masoli M; Heaney L; Haitchi HM; Kurukulaaratchy R; Fulton O; Frankemolle B; Gibson T; Needham K; Howarth P; Djukanovic R; Bel E; Hyland M
  • Article: EUROPEAN RESPIRATORY JOURNAL. 2020;55(1):1901163
    van Bragt JJMH; Adcock IM; Bel EHD; Braunstahl G-J; ten Brinke A; Busby J; Canonica GW; Cao H; Chung KF; Csoma Z; Dahlen B; Davin E; Hansen S; Heffler E; Horvath I; Korn S; Kots M; Kuna P; Kwon N; Louis R; Plaza V; Porsbjerg C; Ramos-Barbon D; Richards LB; Skrgat S; Sont JK; Vijverberg SJH; Weersink EJM; Yasinska V; Wagers SS; Djukanovic R; Maitland-van der Zee AH; Abenhardt B; Adcock IM; Adler J; Alfonso R; Ali R; Alkameh S; Almonacid Sanchez C; Alvares L; Anderson G; Assing K; Ayre S; Becker J; Bel EHD; Bergmann K; Bieksiene K; Bjerring N; Blasi F; Bloemen P; Blum H; Boeing S; Bonavia M; Bossios A; Bourdin A; Braunstahl G-J; Brons A; Brusselle G; Buis J; Busby J; Caiaffa M; Calabrese C; Camiciottoli G; Canonica GW; Cao H; Caruso C; Castilla Martinez M; Centanni S; Chung KF; Cisneros Serrano C; Corsico A; Cosmi L; Costantino M; Costello R; Crimi N; Csoma Z; Dahlen S; Dahlen B; D'Amato M; Davies D; Davin E; Garcia-Cosio Piqueras FDB; Decarlo G; Deimling A; Del Giacco S; Diaz Campos R; Djandji M; Djukanovic R; Doberer D; Dupont L; Dyett K; Edelbaher N; Edelmann M; Ehmann R; Ekberg-Jansson A; Farsi A; Favero E; Feimer J; Fletcher M; Foschino B; Frankemolle B; Gaga M; Gappa M; Garcia de Pedro J; Garcia Rivero J; Gasplmayr M; Gebhardt R; Geldmacher H; Geltner C; Gerstlauer M; Gibson T; Giuseppe G; Gogoll C; Grimm-Sachs V; Grisle I; Gruen B; Gruenewaldt A; Guarnieri G; Gullon Blanco J; Hamelmann E; Hamerlijnck D; Hammers-Reinhard A; Hanon S; Hansen S; Harzheim D; Heaney L; Heffler E; Hellmich S; Herden M; Hering T; Herth F; Hilberg O; Horvath I; Howarth P; Hubatsch M; Humbert M; Husemann K; Idzko M; Jackson D; Jandl M; Jaumont X; Joos G; Joest M; Juech M; Kabesch M; Kaiser-Labusch P; Kardos P; Kaessner F; Keeley T; Kerr W; Kirschner J; Klimek L; Koca M; Koczulla R; Koerner-Rettberg C; Kopac P; Korn S; Kots M; Kronsbein J; Kuna P; Lipinska IK; Kwon N; Langer M; Langeveld B; Lantz A; Lazarinis N; Lazic Z; Lehtimaki L; Leuppi J; Lombardi C; Lommatzsch M; Lopez-Vina A; Louis R; Luca R; Ludviksdottir D; Luettecke-Hecht C; Macchia L; Magni T; Maitland-van der Zee AH; Martinez Rivera C; Mastoridis P; Mazza F; Menzella F; Menzies-Gow A; Michils A; Mihaltan F; Milanese M; Milger-Kneidinger K; Molinska J; Montagna I; Montuschi P; Muelleneisen N; Munoz Esquerre M; Nanzer-Kelly A; Nenasheva N; Neurohr C; Nucera E; Otker J; Oud K; Paggiaro P; Parente R; Parkinson J; Passalacqua G; Patberg N; Patella V; Patino O; Paulsson T; Peche R; Pelaia G; Peress E; Perez de Llano L; Pfeffer P; Pfister P; Pilette C; Pinedo Sierra C; Pini L; Plaza V; Porsbjerg C; Powitz F; Ramos-Barbon D; Ranger T; Rasmussen L; Rasmussen K; Rezelj M; Ricciardi L; Ricciardolo F; Richards LB; Ridolo E; Rijssenbeek-Nouwens L; Rolla G; Romero Ribate D; Ruediger S; Safioti G; Sandstrom T; Santus P; Sauer R; Schauerte G; Schipmann R; Schleich F; Schmid J; Schmidt F; Schmidt O; Schmitz M; Schrag T; Schroeer S; Schultz K; Schulz C; Scichilone N; Sedlak V; Selb J; Senna G; Sergejeva S; Serrano Pariente J; Sichau M; Simona D; Singer A; Skowasch D; Skrgat S; Smeenk F; Smith S; Solidoro P; Sont JK; Spadaro G; Spanevello A; Stefansdottir M; Steinmetz K; Steiss J; Stephan M; Stieglitz S; Suhling H; Taube C; ten Brinke A; Yavuz ST; Tudoric N; Ulrik C; van Bragt JJMH; van de Ven M; van den Elshout F; Van Dyke M; Van Nederveen-Bendien S; van Veen I; Vandenplas O; Velthove K; Vianello A; Vijverberg SJH; Vogelberg C; Wagers SS; Wallen-Nielsen E; Weersink EJ; Wisskirchen T; Yacoub M; Yancey S; Yasinska V; Zappa M; Zielen S; Zimmermann C; Zimmermann R

Alla övriga publikationer

Forskningsbidrag

  • Swedish Heart-Lung Foundation
    1 January 2024 - 31 December 2026
    Bakgrund: Asthma affects approximately 400 million people globally, of which approximately 4% suffer from severe asthma with significantly reduced lung function, quality of life and life expectancy. Novel biological treatments have revolutionized treatment of severe asthma but far from all patients respond to such drugs. Hence, there is an urgent need for improved usage of biologics and increased knowledge of disease mechanisms to identify novel treatment targets. Målsättning: We will perform a detailed transcriptional and functional characterization of innate lymphoid cells (ILCs) and T cells in blood, bronchial biopsies and sputum from patients with severe non-allergic eosinophilic asthma. The aim with these unprecedented explorations is to unveil dysregulated lymphocytes, which contribution to asthma will be determined functionally. Finally, we will explore dysregulated lymphocytes, particularly type 2 ILCs and T cells, before and during biologics therapy. Through these studies we aim to find predictive markers of biologics therapy response and to identify immunological signatures of response. This is possible through our existing fruitful clinical collaborations and our extensive immunological competence. Arbetsplan: Using single-cell gene expression analysis (scRNAseq), we will reveal previously unknown heterogeneity and dysregulation of ILCs and T cells in bronchial biopsies and sputum of patients with severe asthma as compared to healthy controls. High-resolution flow cytometry will be used to validate the results and to develop a clinical method for sputum eosinophil measurements. We will also perform functional lymphocyte analyses to determine how dysregulated lymphocytes develop in the airways and how they contribute to asthma. Finally, we will perform longitudinal assessments of ILCs and T cells in blood and bronchial biopsies of severe asthma patients that are starting biologics therapy (anti-IL-5: mepolizumab, anti-IL-5R: benralizumab
    anti-IL-4/13Ra: dupilumab). Betydelse: In summary, our ambitious, yet feasible studies are likely to advance the understanding of how ILCs and T cells are dysregulated in severe asthma, and how this information can be used to predict response to therapy. If successful, more personalized treatment would improve treatment responses and unnecessary therapies could be avoided. This is clearly important from both a socioeconomic as well as from an individual perspective.
  • Swedish Heart-Lung Foundation
    1 January 2023 - 31 December 2023

Anställningar

  • PostDoc, Medicin, Huddinge, Karolinska Institutet, 2024-
  • Postdoktorala Studier, Medicin, Huddinge, Karolinska Institutet, 2022-2025
  • Doktorand, Severe Asthma, clinical outcomes and biomarkers, Medicin, Huddinge, Karolinska Institutet, 2016-2023

Examina och utbildning

  • Medicine Doktorsexamen, Institutionen för medicin, Huddinge, Karolinska Institutet, 2024

Nyheter från KI

Kalenderhändelser från KI