Tim Willinger

Publikationer
CV
Populärvetenskap och samverkan

Utvalda publikationer

Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2022;219(2):e20210987
CD116⁺ fetal precursors migrate to the perinatal lung and give rise to human alveolar macrophages
Evren E; Ringqvist E; Doisne J-M; Thaller A; Sleiers N; Flavell RA; Di Santo JP; Willinger T
Article: IMMUNITY. 2021;54(2):259-275.e7
Distinct developmental pathways from blood monocytes generate human lung macrophage diversity
Evren E; Ringqvist E; Tripathi KP; Sleiers N; Rives IC; Alisjahbana A; Gao Y; Sarhan D; Halle T; Sorini C; Lepzien R; Marquardt N; Michaelsson J; Smed-Sorensen A; Botling J; Karlsson MCI; Villablanca EJ; Willinger T
Review: IMMUNOLOGY. 2020;160(2):126-138
Origin and ontogeny of lung macrophages: from mice to humans
Evren E; Ringqvist E; Willinger T
Article: IMMUNITY. 2018;48(1):120-132.e8
Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation
Emgard J; Kammoun H; Garcia-Cassani B; Chesne J; Parigi SM; Jacob J-M; Cheng H-W; Evren E; Das S; Czarnewski P; Sleiers N; Melo-Gonzalez F; Kvedaraite E; Svensson M; Scandella E; Hepworth MR; Huber S; Ludewig B; Peduto L; Villablanca EJ; Veiga-Fernandes H; Pereira JOP; Flavell RA; Willinger T
Article: NATURE BIOTECHNOLOGY. 2014;32(4):364-372
Development and function of human innate immune cells in a humanized mouse model
Rongvaux A; Willinger T; Martinek J; Strowig T; Gearty SV; Teichmann LL; Saito Y; Marches F; Halene S; Palucka AK; Manz MG; Flavell RA

Artiklar

Article: DISCOV IMMUNOL. 2023;2(1):kyad007
Single-cell RNA sequencing of human lung innate lymphoid cells in the vascular and tissue niche reveals molecular features of tissue adaptation.
Alisjahbana A; Mohammad I; Gao Y; Evren E; Willinger T
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:902881
A single-cell map of vascular and tissue lymphocytes identifies proliferative TCF-1⁺ human innate lymphoid cells
Gao Y; Alisjahbana A; Boey DZH; Mohammad I; Sleiers N; Dahlin JS; Dahlin S; Willinger T
Article: SCIENCE IMMUNOLOGY. 2021;6(56):eabb7800
Continuous human uterine NK cell differentiation in response to endometrial regeneration and pregnancy
Strunz B; Bister J; Jonsson H; Filipovic I; Crona-Guterstam Y; Kvedaraite E; Sleiers N; Dumitrescu B; Brannstrom M; Lentini A; Reinius B; Cornillet M; Willinger T; Gidlof S; Hamilton RS; Ivarsson MA; Bjorkstrom NK
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:752104
CD5 Surface Expression Marks Intravascular Human Innate Lymphoid Cells That Have a Distinct Ontogeny and Migrate to the Lung
Alisjahbana A; Gao Y; Sleiers N; Evren E; Brownlie D; von Kries A; Jorns C; Marquardt N; Michaelsson J; Willinger T
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2019;216(4):728-742
Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria
Melo-Gonzalez F; Kammoun H; Evren E; Dutton EE; Papadopoulou M; Bradford BM; Tanes C; Fardus-Reid F; Swann JR; Bittinger K; Mabbott NA; Valance BA; Willinger T; Withers DR; Hepworth MR
Journal article: NATURE BIOTECHNOLOGY. 2017;35(12):1211
Development and function of human innate immune cells in a humanized mouse model (vol 32, pg 364, 2014)
Rongvaux A; Willinger T; Martinek J; Strowig T; Gearty SV; Teichmann LL; Saito Y; Marches F; Halene S; Palucka AK; Manz MG; Flavell RA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(14):4423-4428
Dynamin 2-dependent endocytosis sustains T-cell receptor signaling and drives metabolic reprogramming in T lymphocytes
Willinger T; Staron M; Ferguson SM; De Camilli P; Flavell RA
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2014;211(4):685-700
Dynamin 2-dependent endocytosis is required for sustained S1PR1 signaling
Willinger T; Ferguson SM; Pereira JP; De Camilli P; Flavell RA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(22):8670-8675
Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis
Willinger T; Flavell RA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(6):2378-2383
Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo
Rongvaux A; Willinger T; Takizawa H; Rathinam C; Auerbach W; Murphy AJ; Valenzuela DM; Yancopoulos GD; Eynon EE; Stevens S; Manz MG; Flavell RA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(6):2390-2395
Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung
Willinger T; Rongvaux A; Takizawa H; Yancopoulos GD; Valenzuela DM; Murphy AJ; Auerbach W; Eynon EE; Stevens S; Manz MG; Flavell RA
Article: CELL HOST AND MICROBE. 2010;8(4):369-376
A Mouse Model for the Human Pathogen Salmonella Typhi
Song J; Willinger T; Rongvaux A; Eynon EE; Stevens S; Manz MG; Flavell RA; Galan JE
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(24):9785-9790
Requirement for AHNAK1-mediated calcium signaling during T lymphocyte cytolysis
Matza D; Badou A; Jha MK; Willinger T; Antov A; Sanjabi S; Kobayashi KS; Marchesi VT; Flavell RA
Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2009;20(1):86-94
Disruption of Myosin 1e Promotes Podocyte Injury
Krendel M; Kim SV; Willinger T; Wang T; Kashgarian M; Flavell RA; Mooseker MS
Article: JOURNAL OF IMMUNOLOGY. 2006;176(3):1439-1446
Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo
Willinger T; Freeman T; Herbert M; Hasegawa H; McMichael AJ; Callan MFC
Article: JOURNAL OF IMMUNOLOGY. 2005;175(9):5895-5903
Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets
Willinger T; Freeman T; Hasegawa H; McMichael AJ; Callan MFC
Article: BLOOD. 2001;97(10):3138-3145
Targeting of a B7-1 (CD80) immunoglobulin G fusion protein to acute myeloid leukemia blasts increases their costimulatory activity for autologous remission T cells
Notter M; Willinger T; Erben U; Thiel E

Alla övriga publikationer

Editorial comment: CELLS. 2023;12(2):241
Implication of Oxysterols in Infectious and Non-Communicable Inflammatory Diseases
Lizard G; Mackrill JJJ; Willinger T
Book chapter: ENCYCLOPEDIA OF RESPIRATORY MEDICINE. 2022;p. 190-199
Pulmonary Macrophages☆
Willinger T
Editorial comment: FRONTIERS IN IMMUNOLOGY. 2021;12:829644
Advances in Human Immune System Mouse Models for Studying Human Hematopoiesis and Cancer Immunotherapy
Saito Y; Willinger T; Theocharides APA
Review: BIOCHEMICAL PHARMACOLOGY. 2020;174:113672
Human macrophages and innate lymphoid cells: Tissue-resident innate immunity in humanized mice
Alisjahbana A; Mohammad I; Gao Y; Evren E; Ringqvist E; Willinger T
Editorial comment: IMMUNITY. 2019;51(5):786-788
Metabolite Sensing by Colonic ILC3s: How Far Is Too Ffar2 Go?
Alisjahbana A; Willinger T
Review: JOURNAL OF INTERNAL MEDICINE. 2019;285(4):367-380
Oxysterols in intestinal immunity and inflammation
Willinger T
Review: FRONTIERS IN IMMUNOLOGY. 2019;10:2010
Metabolic Control of Innate Lymphoid Cell Migration
Willinger T
Editorial comment: CELL STEM CELL. 2014;14(1):3-4
ESCaping Rejection: A Step Forward for Embryonic-Stem-Cell-Based Regenerative Medicine
Willinger T; Flavell RA
Review: ANNUAL REVIEW OF IMMUNOLOGY. 2013;31:635-674
Human Hemato-Lymphoid System Mice: Current Use and Future Potential for Medicine
Rongvaux A; Takizawa H; Strowig T; Willinger T; Eynon EE; Flavell RA; Manz MG
Review: TRENDS IN IMMUNOLOGY. 2011;32(7):321-327
Improving human hemato-lymphoid-system mice by cytokine knock-in gene replacement
Willinger T; Rongvaux A; Strowig T; Manz MG; Flavell RA
Editorial comment: CELL HOST AND MICROBE. 2009;6(1):5-9
Humanized Mice for Modeling Human Infectious Disease: Challenges, Progress, and Outlook
Legrand N; Ploss A; Balling R; Becker PD; Borsotti C; Brezillon N; Debarry J; de Jong Y; Deng H; Di Santo JP; Eisenbarth S; Eynon E; Flavell RA; Guzman CA; Huntington ND; Kremsdorf D; Manns MP; Manz MG; Mention J-J; Ott M; Rathinam C; Rice CM; Rongvaux A; Stevens S; Spits H; Strick-Marchand H; Takizawa H; van Lent AU; Wang C; Weijer K; Willinger T; Ziegler P

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Examina och utbildning

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