Thale Kristin Olsen

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: JOURNAL OF CLINICAL INVESTIGATION. 2024;134(21):e175310
Epigenetic regulation of cell state by H2AFY governs immunogenicity in high-risk neuroblastoma
Nagarajan D; Parracho RT; Corujo D; Xie M; Kutkaite G; Olsen TK; Bedos MR; Salehi M; Baryawno N; Menden MP; Chen X; Buschbeck M; Mao Y
Article: MOLECULAR CANCER. 2024;23(1):180
Joint single-cell genetic and transcriptomic analysis reveal pre-malignant SCP-like subclones in human neuroblastoma
Olsen TK; Otte J; Mei S; Embaie BT; Kameneva P; Cheng H; Gao T; Zachariadis V; Tsea I; Bjorklund A; Kryukov E; Hou Z; Johansson A; Sundstrom E; Martinsson T; Fransson S; Stenman J; Fard SS; Johnsen JI; Kogner P; Adameyko I; Enge M; Kharchenko PV; Baryawno N
Article: JCI INSIGHT. 2024;9(6):e173337
Single-cell analyses of metastatic bone marrow in human neuroblastoma reveals microenvironmental remodeling and metastatic
Mei S; Alchahin AM; Embaie BT; Gavriliuc IM; Verhoeven BM; Zhao T; Li X; Jeffries NE; Pepich A; Sarkar H; Olsen TK; Wickstrom M; Stenman J; Reina-Bedoya O; Kharchenko PV; Saylor PJ; Johnsen JI; Sykes DB; Kogner P; Baryawno N
Article: CANCER RESEARCH. 2022;82(24):4586-4603
Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
Borgenvik A; Holmberg KO; Bolin S; Zhao M; Savov V; Rosen G; Hutter S; Garancher A; Rahmanto AS; Bergstrom T; Olsen TK; Mainwaring OJ; Sattanino D; Verbaan AD; Rusert JM; Sundstrom A; Bravo MB; Dang Y; Wenz AS; Richardson S; Fotaki G; Hill RM; Dubuc AM; Kalushkova A; Remke M; Cancer M; Jernberg-Wiklund H; Giraud G; Chen X; Taylor MD; Sangfelt O; Clifford SC; Schueller U; Wechsler-Reya RJ; Weishaupt H; Swartling FJ
Article: JCI INSIGHT. 2022;7(17):e153836
DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma
Olsen TK; Dyberg C; Embaie BT; Alchahin A; Milosevic J; Ding J; Otte J; Tummler C; Myrberg IH; Westerhout EM; Koster J; Versteeg R; Ding H-F; Kogner P; Johnsen JI; Sykes DB; Baryawno N
Article: CELL REPORTS MEDICINE. 2022;3(6):100657
The immune cell atlas of human neuroblastoma
Verhoeven BM; Mei S; Olsen TK; Gustafsson K; Valind A; Lindstrom A; Gisselsson D; Fard SS; Hagerling C; Kharchenko PV; Kogner P; Johnsen JI; Baryawno N
Article: LIFE SCIENCES. 2022;295:120394
Omega-3 fatty acids decrease CRYAB, production of oncogenic prostaglandin E₂ and suppress tumor growth in medulloblastoma
Ljungblad L; Bergqvist F; Tummler C; Madawala S; Olsen TK; Andonova T; Jakobsson P-J; Johnsen JI; Pickova J; Strandvik B; Kogner P; Gleissman H; Wickstrom M
Article: CANCER RESEARCH COMMUNICATIONS. 2022;2(3):182-201
MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner
Castell A; Yan Q; Fawkner K; Bazzar W; Zhang F; Wickstrom M; Alzrigat M; Franco M; Krona C; Cameron DP; Dyberg C; Olsen TK; Verschut V; Schmidt L; Lim SY; Mahmoud L; Hydbring P; Lehmann S; Baranello L; Nelander S; Johnsen JI; Larsson L-G
Article: CANCERS. 2021;13(21):5493
High Expression of PPM1D Induces Tumors Phenotypically Similar to TP53 Loss-of-Function Mutations in Mice
Milosevic J; Fransson S; Gulyas M; Olsen TK; Gallo-Oller G; Treis D; Elfman LHM; Wilhelm M; Martinsson T; Baryawno N; Kogner P; Johnsen JI
Article: NATURE GENETICS. 2021;53(5):694-706
Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin
Kameneva P; Artemov AV; Kastriti ME; Faure L; Olsen TK; Otte J; Erickson A; Semsch B; Andersson ER; Ratz M; Frisen J; Tischler AS; de Krijger RR; Bouderlique T; Akkuratova N; Vorontsova M; Gusev O; Fried K; Sundstrom E; Mei S; Kogner P; Baryawno N; Kharchenko PV; Adameyko I
Article: CANCER DISCOVERY. 2020;10(7):942-963
Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes
Clarke M; Mackay A; Ismer B; Pickles JC; Tatevossian RG; Newman S; Bale TA; Stoler I; Izquierdo E; Temelso S; Carvalho DM; Molinari V; Burford A; Howell L; Virasami A; Fairchild AR; Avery A; Chalker J; Kristiansen M; Haupfear K; Dalton JD; Orisme W; Wen J; Hubank M; Kurian KM; Rowe C; Maybury M; Crosier S; Knipstein J; Schueller U; Kordes U; Kram DE; Snuderl M; Bridges L; Martin AJ; Doey LJ; Al-Sarraj S; Chandler C; Zebian B; Cairns C; Natrajan R; Boult JKR; Robinson SP; Sill M; Dunkel IJ; Gilheeney SW; Rosenblum MK; Hughes D; Proszek PZ; Macdonald TJ; Preusser M; Haberler C; Slavc I; Packer R; Ng H-K; Caspi S; Popovi M; Kotnik BF; Wood MD; Baird L; Davare MA; Solomon DA; Olsen TK; Brandal P; Farrell M; Cryan JB; Capra M; Karremann M; Schittenhelm J; Schuhmann MU; Ebinger M; Dinjens WNM; Kerl K; Hettmer S; Pietsch T; Andreiuolo F; Driever PH; Korshunov A; Hiddingh L; Worst BC; Sturm D; Zuckermann M; Witt O; Bloom T; Mitchell C; Miele E; Colafati GS; Diomedi-Camassei F; Bailey S; Moore AS; Hassall TEG; Lowis SP; Tsoli M; Cowley MJ; Ziegler DS; Karajannis MA; Aquilina K; Hargrave DR; Carceller F; Marshall LV; von Deimling A; Kramm CM; Pfister SM; Sahm F; Baker SJ; Mastronuzzi A; Carai A; Vinci M; Capper D; Popov S; Ellison DW; Jacques TS; Jones DTW; Jones C
Article: NATURE COMMUNICATIONS. 2020;11(1):71
Integrative discovery of treatments for high-risk neuroblastoma
Almstedt E; Elgendy R; Hekmati N; Rosen E; Warn C; Olsen TK; Dyberg C; Doroszko M; Larsson I; Sundstrom A; Henriksson MA; Pahlman S; Bexell D; Vanlandewijck M; Kogner P; Jornsten R; Krona C; Nelander S
Article: FRONTIERS IN ONCOLOGY. 2020;10:598872
Hodgkin Lymphoma Monozygotic Triplets Reveal Divergences in DNA Methylation Signatures
Xia C; Olsen TK; Zirakzadeh AA; Almamoun R; Sjoholm LK; Dahlstrom J; Sjoberg J; Claesson H-E; Johnsen JI; Winqvist O; Xu D; Ekstrom TJ; Bjorkholm M; Straat K
Article: CANCERS. 2019;12(1):E73-73
Inhibition of Rho-Associated Kinase Suppresses Medulloblastoma Growth
Dyberg C; Andonova T; Olsen TK; Brodin B; Kool M; Kogner P; Johnsen JI; Wickstrom M
Article: CURRENT PROTOCOLS IN MOLECULAR BIOLOGY. 2018;122(1):e57
Introduction to Single-Cell RNA Sequencing.
Olsen TK; Baryawno N
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(32):E6603-E6612
Rho-associated kinase is a therapeutic target in neuroblastoma
Dyberg C; Fransson S; Andonova T; Sveinbjornsson B; Lannerholm-Palm J; Olsen TK; Forsberg D; Herlenius E; Martinsson T; Brodin B; Kogner P; Johnsen JI; Wickstrom M
Article: EXPERIMENTAL HEMATOLOGY. 2017;52:32-39
With me or against me: Tumor suppressor and drug resistance activities of SAMHD 1
Herold N; Rudd SG; Sanjiv K; Kutzner J; Myrberg IH; Paulin CBJ; Olsen TK; Helleday T; Henter J-I; Schaller T
Article: SCIENTIFIC REPORTS. 2017;7:46366
Establishment and characterization of an orthotopic patient-derived Group 3 medulloblastoma model for preclinical drug evaluation
Sanden E; Dyberg C; Krona C; Gallo-Oller G; Olsen TK; Perez JE; Wickstrom M; Estekizadeh A; Kool M; Visse E; Ekstrom TJ; Siesjo P; Johnsen JI; Darabi A
Article: ONCOGENE. 2017;36(4):570-584
Differential propagation of stroma and cancer stem cells dictates tumorigenesis and multipotency
Behnan J; Stangeland B; Hosainey SAM; Joel M; Olsen TK; Micci F; Glover JC; Isakson P; Brinchmann JE
Article: GENES CHROMOSOMES AND CANCER. 2016;55(12):944-953
Novel fusion genes and chimeric transcripts in ependymal tumors.
Olsen TK; Panagopoulos I; Gorunova L; Micci F; Andersen K; Kilen Andersen H; Meling TR; Due-Tønnessen B; Scheie D; Heim S; Brandal P
Article: NEURO-ONCOLOGY. 2015;17(10):1365-1373
Fusion genes with ALK as recurrent partner in ependymoma-like gliomas: a new brain tumor entity?
Olsen TK; Panagopoulos I; Meling TR; Micci F; Gorunova L; Thorsen J; Due-Tønnessen B; Scheie D; Lund-Iversen M; Krossnes B; Saxhaug C; Heim S; Brandal P
Article: ONCOLOGY REPORTS. 2014;32(2):483-490
Genomic characterization of ependymomas reveals 6q loss as the most common aberration.
Olsen TK; Gorunova L; Meling TR; Micci F; Scheie D; Due-Tønnessen B; Heim S; Brandal P
Article: CANCER MEDICINE. 2014;3(4):812-824
U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells.
Torsvik A; Stieber D; Enger PØ; Golebiewska A; Molven A; Svendsen A; Westermark B; Niclou SP; Olsen TK; Chekenya Enger M; Bjerkvig R
Article: CYTOJOURNAL. 2012;9:8
Establishing a protocol for immunocytochemical staining and chromogenic in situ hybridization of Giemsa and Diff-Quick prestained cytological smears.
Beraki E; Olsen TK; Sauer T
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Conference publication: EUROPEAN JOURNAL OF HUMAN GENETICS. 2024;32:545-546
Occurrence of cancer in Marfan syndrome: report of two females with neuroblastoma and review of the literature
Gonzalez CM; Taylan F; Tesi B; Lagerstedt-Robinson K; Wessman S; Stenman J; Fagman H; Olsen TK; Georgantzi K; de Stahl TD; Ek T; Palmer R; Forsberg S; Martinsson T; Kogner P; Nordgren A
Conference publication: NEURO-ONCOLOGY. 2023;25:i62
SINGLE-CELL TRANSCRIPTOMIC ANALYSIS REVEALS DISTINCT GENOMIC LANDSCAPES, CELL TRAJECTORIES, AND TUMOUR-MICROENVIRONMENT INTERACTIONS IN FOUR SUBTYPES OF MEDULLOBLASTOMA
Ruchiy Y; Tsea I; Verhoeven BM; Sinha I; Preka E; Olsen TK; Mei S; Blomgren K; Johnsen JI; Carlson L-M; Dyberg C; Baryawno N
Conference publication: CANCER RESEARCH. 2022;82(12)
Single-cell landscape of the TH-MYCN neuroblastoma mouse model
Embaie BT; Alchahin A; Olsen TK; Sarkar H; Mei S; Baryawno N
Conference publication: CANCER RESEARCH. 2022;82(12)
The immune cell atlas of human neuroblastoma
Verhoeven BM; Mei S; Olsen TK; Gustafsson KK; Valind A; Lindstrom A; Nord DG; Fard SS; Hagerling C; Kharchenko PV; Kogner P; Johnsen JI; Baryawno N
Conference publication: CANCER RESEARCH. 2022;82(12)
The immune cell atlas of human neuroblastoma.
Verhoeven BM; Mei S; Olsen TK; Gustafsson KK; Valind A; Lindstrom A; Nord DG; Fard SS; Hagerling C; Kharchenko PV; Kogner P; Johnsen JI; Baryawno N
Preprint: BIORXIV. 2021
DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma
Olsen TK; Dyberg C; Embaie B; Alchahin A; Milosevic J; Otte J; Tümmler C; Myrberg IH; Westerhout E; Koster J; Versteeg R; Kogner P; Johnsen JI; Sykes D; Baryawno N
Preprint: BIORXIV. 2020
PPM1D is a neuroblastoma oncogene and therapeutic target in childhood neural tumors
Milosevic J; Fransson S; Gulyas M; Gallo-Oller G; Olsen T; Treis D; Wickström M; Elfman LHM; Sveinbjornsson B; Hertwig F; Bartenhagen C; Reinsbach S; Wilhelm M; Abel F; Javanmardi N; Thankaswamy-Kosalai S; Eissler N; Kock A; Shi Y; Tanino K; Hehir-Kwa J; Mensenkamp A; Tytgat GAM; Kanduri C; Holmberg J; Gisselsson D; Molenaar J; Jongmans M; Fischer M; Kool M; Sakaguchi K; Baryawno N; Martinsson T; Johnsen JI; Kogner P
Preprint: BIORXIV. 2020
Malignant Schwann cell precursors mediate intratumoral plasticity in human neuroblastoma
Olsen T; Otte J; Mei S; Kameneva P; Björklund Å; Kryukov E; Hou Z; Johansson A; Sundström E; Martinsson T; Fransson S; Johnsen JI; Kogner P; Adameyko I; Kharchenko P; Baryawno N
Conference publication: PEDIATRIC BLOOD AND CANCER. 2020;67:S3
Malignant Schwann Cell Precursors Mediate Intratumoral Plasticity in Human Neuroblastoma
Olsen TK; Otte J; Mei S; Kameneva P; Bjorklund A; Kryukov E; Hou Z; Johansson A; Sundstrom E; Martinsson T; Fransson S; Johnsen JI; Kogner P; Adameyko I; Kharchenko P; Baryawno N
Conference publication: BLOOD. 2017;130
MAPKAP1 (Sin1), a Key Component of the MTORC2 Complex, Confers Resistance to Sorafenib and Correlates with Adverse Clinical Outcomes in Acute Myeloid Leukemia
Khoury JD; Xagoraris I; Tsesmetzis N; Myrberg IHH; Olsen TK; Ng SB; Chng W-J; Yan B; Ng CH; Andreeff M; Medeiros LJ; Kantarjian HM; Herold N; Grander D; Rassidakis G

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