Stephan Meinke

Om mig
Publikationer
Populärvetenskap och samverkan

Om mig

Jag är forskningspecialist inom immunologi och arbetar i både Petter Höglunds och Evren Alicis grupp på HERM.

Artiklar

Article: BLOOD ADVANCES. 2024;8(3):571-580
Clinical and immunological features in ACKR1/DARC-associated neutropenia
Palmblad J; Sohlberg E; Nilsson CC; Lindqvist H; Deneberg S; Ratcliffe P; Meinke S; Mortberg A; Klimkowska M; Hoglund P
Article: SCIENCE SIGNALING. 2023;16(780):eabq0752
SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency
Schmied L; Luu TT; Sondergaard JN; Hald SH; Meinke S; Mohammad DK; Singh SB; Mayer C; Casoni GP; Chrobok M; Schlums H; Rota G; Truong HM; Westerberg LS; Guarda G; Alici E; Wagner AK; Kadri N; Bryceson YT; Saeed MB; Hoglund P
Journal article: HEMASPHERE. 2022;6(Suppl):1318-1319
P1435: PRECLINICAL EVALUATION OF ZILOVERTAMAB‐BASED ANTI‐ROR1 CHIMERIC ANTIGEN RECEPTORS IN NK AND T CELLS
Meinke S; Kadri N; Bi S; Bostancioglu B; Markey C; Breitmeyer JB; Hussain A; Krishnan R; Kaufmann GF; Alici E
Journal article: HEMASPHERE. 2022;6(Suppl ):1326-1327
P1443: AUTOLOGOUS NK CELLS AS CONSOLIDATION AFTER FRONT-LINE STEM CELL TRANSPLANTATION IN MULTIPLE MYELOMA: A LONG-TERM FOLLOW-UP
Lund J; Nahi H; Meinke S; Holmqvist P-H; Ljunggren H-G; Aschan J; Alici E
Article: CELL REPORTS MEDICINE. 2022;3(2):100508
Autologous NK cells as consolidation therapy following stem cell transplantation in multiple myeloma
Nahi H; Chrobok M; Meinke S; Gran C; Marquardt N; Afram G; Sutlu T; Gilljam M; Stellan B; Wagner AK; Blomberg P; Holmqvist P-H; Walther-Jallow L; Mellstrom K; Liwing J; Gustafsson C; Mansson R; Klimkowska M; Gahrton G; Lund J; Ljungman P; Ljunggren H-G; Alici E
Article: BLOOD. 2022;139(5):704-716
Perturbed NK-cell homeostasis associated with disease severity in chronic neutropenia
Sohlberg E; Pfefferle A; Ask EH; Tschan-Plessl A; Jacobs B; Netskar H; Lorenz S; Kanaya M; Kosugi-Kanaya M; Meinke S; Mortberg A; Hoglund P; Sundin M; Carlsson G; Palmblad J; Malmberg K-J
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:854312
FOXO1 and FOXO3 Cooperatively Regulate Innate Lymphoid Cell Development
Luu TT; Sondergaard JN; Pena-Perez L; Kharazi S; Krstic A; Meinke S; Schmied L; Frengen N; Heshmati Y; Kierczak M; Bouderlique T; Wagner AK; Gustafsson C; Chambers BJ; Achour A; Kutter C; Hoglund P; Mansson R; Kadri N
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2022;196(1):224-233
Platelet transfusion improves clot formation and platelet function in severely thrombocytopenic haematology patients
Karlstrom C; Gryfelt G; Schmied L; Meinke S; Hoglund P
Article: HEMASPHERE. 2021;5(5):e564
Ibrutinib Has Time-dependent On- and Off-target Effects on Plasma Biomarkers and Immune Cells in Chronic Lymphocytic Leukemia
Mulder TA; Pena-Perez L; Berglof A; Meinke S; Estupinan HY; Heimersson K; Zain R; Mansson R; Smith CIE; Palma M
Article: LIFE SCIENCE ALLIANCE. 2021;4(4):e202000723
Short-term IL-15 priming leaves a long-lasting signalling imprint in mouse NK cells independently of a metabolic switch
Luu TT; Schmied L; Nguyen N-A; Wiel C; Meinke S; Mohammad DK; Bergo M; Alici E; Kadri N; Ganesan S; Hoglund P
Article: TRANSFUSION. 2021;61(4):1222-1234
HLA class I depletion by citric acid, and irradiation of apheresis platelets for transfusion of refractory patients
Mirlashari MR; Vetlesen A; Nissen-Meyer LSH; Naper C; Tjonnfjord GE; Njerve IU; Ezligini F; Landmark BF; Meinke S; Sandgren P; Hoglund P; Hetland G
Journal article: HEMASPHERE. 2021;5(5)
Ibrutinib Has Time-dependent On- and Off-target Effects on Plasma Biomarkers and Immune Cells in Chronic Lymphocytic Leukemia
Mulder TA; Pena-Perez L; Berglof A; Meinke S; Estupinan HY; Heimersson K; Zain R; Mansson R; Smith CIE; Palma M
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2020;50(4):494-504
IL-15 and CD155 expression regulate LAT expression in murine DNAM1⁺ NK cells, enhancing their effectors functions
Luu TT; Wagner AK; Schmied L; Meinke S; Freund JE; Kambayashi T; Ravens I; Achour A; Bernhardt G; Chambers BJ; Hoglund P; Kadri N
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2249
The Complement System Is Essential for the Phagocytosis of Mesenchymal Stromal Cells by Monocytes
Gavin C; Meinke S; Heldring N; Heck KA; Achour A; Iacobaeus E; Le Blanc K; Kadri N; Hoglund P
Article: TRANSFUSION. 2018;58(11):2657-2668
Cryopreservation of buffy coat-derived platelet concentrates photochemically treated with amotosalen and UVA light
Meinke S; Wikman A; Gryfelt G; Hultenby K; Uhlin M; Hoeglund P; Sandgren P
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2018;183(2):212-224
Ibrutinib induces rapid down-regulation of inflammatory markers and altered transcription of chronic lymphocytic leukaemia-related genes in blood and lymph nodes
Palma M; Krstic A; Perez LP; Bergloef A; Meinke S; Wang Q; Blomberg KEM; Kamali-Moghaddam M; Shen Q; Jaremko G; Lundin J; De Paepe A; Hoeglund P; Kimby E; OEsterborg A; Mansson R; Smith CIE
Article: THROMBOSIS RESEARCH. 2018;162:69-76
Adding to the complexity of fetal and neonatal alloimmune thrombocytopenia: Reduced fibrinogen binding in the presence of anti-HPA-1a antibody and hypo-responsive neonatal platelets
Refsum E; Meinke S; Gryfelt G; Wikman A; Hoglund P
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(3):135-142
The Abl-1 Kinase is Dispensable for NK Cell Inhibitory Signalling and is not Involved in Murine NK Cell Education
Ganesan S; Luu TT; Chambers BJ; Meinke S; Brodin P; Vivier E; Wetzel DM; Koleske AJ; Kadri N; Hoglund P
Journal article: ISBT SCIENCE SERIES. 2017;12(1):148-153
HLA‐stripped platelets: preclinical developments and clinical outlooks
Meinke S; Karlström C; Gryfelt G; Wikman A; Höglund P
Article: TRANSFUSION MEDICINE. 2017;27(1):43-51
Characterisation of maternal human leukocyte antigen class I antibodies in suspected foetal and neonatal alloimmune thrombocytopenia
Refsum E; Mortberg A; Dahl J; Meinke S; Auvinen M-K; Westgren M; Reilly M; Hoglund P; Wikman A
Article: VOX SANGUINIS. 2017;112(1):33-39
Storage of red blood cells in a novel polyolefin blood container: a pilot in vitro study
Gulliksson H; Meinke S; Ravizza A; Larsson L; Hoglund P
Article: SCIENTIFIC REPORTS. 2016;6:37996
Independent control of natural killer cell responsiveness and homeostasis at steady-state by CD11c+dendritic cells
Thuy TL; Ganesan S; Wagner AK; Sarhan D; Meinke S; Garbi N; Haemmerling G; Alici E; Karre K; Chambers BJ; Hoglund P; Kadri N
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2016;434:9-15
Sensitive detection of platelet-specific antibodies with a modified MAIPA using biotinylated antibodies and streptavidin-coated beads
Mortberg A; Meinke S; Berg P; Killie MK; Kjeldsen-Kragh J; Jaras K; Refsum E; Hoglund P; Wikman A
Article: TRANSFUSION. 2016;56(2):370-369
Platelets made HLA deficient by acid treatment aggregate normally and escape destruction by complement and phagocytes in the presence of HLA antibodies
Meinke S; Sandgren P; Mortberg A; Karlstrom C; Kadri N; Wikman A; Hoglund P
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2015;45(7):2134-2142
Inhibition of NKp30-and 2B4-mediated NK cell activation by evolutionary different human and bovine CEACAM1 receptors
Merkt W; Urlaub D; Meinke S; Kammerer R; Watzl C
Article: TRANSFUSION. 2014;54(3):602-612
Random aggregates in newly produced platelet units are associated with platelet activation and release of the immunomodulatory factors sCD40L and RANTES
Sandgren P; Meinke S; Eckert E; Douagi I; Wikman A; Hoglund P
Article: FRONTIERS IN IMMUNOLOGY. 2013;4:3
NK cell cytotoxicity mediated by 2B4 and NTB-A is dependent on SAP acting downstream of receptor phosphorylation
Meinke S; Watzl C
Article: FRONTIERS IN BIOSCIENCE - LANDMARK. 2008;13:956-965
Regulation of NK cell activity by 2B4, NTB-A and CRACC
Claus M; Meinke S; Bhat R; Watzl C
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2007;37(1):193-198
Modulation of 2B4 (CD244) activity and regulated SAP expression in human NK cells
Endt J; Eissmann P; Hoffmann SC; Meinke S; Giese T; Watzl C
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(5):2489-2496
Activation of T cell calcium influx by the second messenger ADP-ribose
Gasser A; Glassmeier G; Fliegert R; Langhorst MF; Meinke S; Hein D; Krüger S; Weber K; Heiner I; Oppenheimer N; Schwarz JR; Guse AH
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Conference publication: BLOOD. 2022;140:12440-12441
HSV1716 Infects Multiple Myeloma Cells and Leads to CD138 Downregulation
Susek KH; Flore VN; Karvouni M; Meinke S; Conner J; Powers C; Allen R; Wagner AK; Alici E
Preprint: BIORXIV. 2022
Control of NK cell tolerance in MHC class I-deficiency by regulated SHP-1 localization to the activating immune synapse
Schmied L; Luu T; Søndergaard J; Meinke S; Mohammad D; Singh S; Mayer C; Casoni G; Chrobok M; Schlums H; Rota G; Truong H; Westerberg L; Guarda G; Alici E; Wagner A; Kadri N; Bryceson Y; Saeed M; Höglund P
Meeting abstract: BLOOD. 2021;138:4796
CD38 Down-Regulation on Ex Vivo Activated and Expanded NK Cells for Cell Therapy Persists after Infusion
Nahi H; Chrobook M; Meinke S; Gran C; Marquardt N; Afram G; Sutlu T; Gilljam M; Stellan B; Wagner AK; Walther-Jallow L; Liwing J; Klimkowska M; Gahrton G; Ljungman P; Ljunggren H-G; Alici E
Preprint: BIORXIV. 2021
FOXO1 and FOXO3 cooperatively regulate innate lymphoid cell development
Luu T; Søndergaard JN; Peña-Pérez L; Kharazi S; Krstic A; Meinke S; Schmied L; Frengen N; Heshmati Y; Kierczak M; Bouderlique T; Wagner AK; Gustafsson C; Chambers B; Achour A; Kutter C; Höglund P; Månsson R; Kadri N
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2021;94(6)
Antibody-dependent natural killer cell cytotoxicity: A potential mechanism of platelet lysis in immune thrombocytopenia
Schmied L; Meinke S; Brandt L; Thanh TL; Karlstrom C; Sandgren P; Vidarsson G; Onfelt B; Hoglund P
Review: FRONTIERS IN IMMUNOLOGY. 2021;12:640578
Platelet-Mediated Protection of Cancer Cells From Immune Surveillance - Possible Implications for Cancer Immunotherapy
Schmied L; Hoglund P; Meinke S
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2021;94(6)
SHP-1 expression and localization are associated with functional education of murine natural killer cells
Luu T; Schmied L; Sondergaard JN; Saeed MB; Meinke S; Mohammad D; Casoni GP; Schlums H; Truong HM; Westerberg L; Bryceson Y; Alici E; Wagner AK; Kadri N; Hoglund P
Conference publication: BLOOD. 2020;136:24-25
Systems-Level Analysis of the Immune Repertoire in Neutropenia Reveal Arrested NK Cell Differentiation and Exhaustion
Sohlberg E; Pfefferle A; Ask EH; Tschan-Plessl A; Jacobs B; Lorenz S; Meinke S; Hoglund P; Sundin M; Karlsson G; Palmblad J; Malmberg K-J
Conference publication: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019;19(10):E169
Combination of herpes-simplex based oncolytic viruses (HSV-OV) with natural killer (NK) cells in Multiple Myeloma
Susek KH; Meinke S; Wagner AK; Ljunggren H-G; Alici E
Review: TRANSFUSION MEDICINE REVIEWS. 2019;33(4):231-235
Complement as an Immune Barrier in Platelet Transfusion Refractoriness
Meinke S; Karlstrom C; Hoglund P
Preprint: SSRN ELECTRONIC JOURNAL. 2019
A Brief IL-15 Pulse Results in JAK3-Dependent Phosphorylation of ITAM-Associated Signaling Molecules and a Long-Lasting Priming Imprint in Mouse NK Cells
Luu TT; Nguyen N-A; Ganesan S; Meinke S; Kadri N; Alici E; Höglund P
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):297
Quantitative measurements of inhibitory signaling in murine Natural Killer cells using a fluorometric assay of calcium flux
Ganesan S; Thuy LT; Kadri N; Meinke S; Hoglund P
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):257-258
Platelets become NK cell targets in the presence of anti-platelet antibodies
Meinke S; Brandt L; Sandgren P; Onfelt B; Hoglund P
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):295
Reactive oxygen species are linked with general phosphorylation status and functional education of natural killer cells
Thuy TL; Vignesh S; Wagner AK; Chrobok M; Schlums H; Tornmalm J; Kadri N; Meinke S; Widengren J; Bryceson Y; Alici E; Johannsson S; Hoglund P
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):295
Interleukin-15 primes natural killer cell functions through proximal crosstalk with activating receptors
Thuy TL; Ngoc AN; Ganesan S; Meinke S; Wagner AK; Chrobok M; Alici E; Hoglund P
Meeting abstract: BLOOD. 2016;128(22):3235
Very Early Effects of Ibrutinib on Tumor and Immune Cells in Blood and Lymph Nodes in Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) Patients
Palma M; Krstic A; Berglof A; Wang Q; Blomberg E; Meinke S; Kamali-Moghaddam M; Shen Q; Jaremko G; Lundin J; Kimby E; Hoglund P; Mansson R; Osterborg A; Smith E
Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2015;82(3):208-217
Targets for Ibrutinib Beyond B Cell Malignancies
Berglof A; Hamasy A; Meinke S; Palma M; Krstic A; Mansson R; Kimby E; Osterborg A; Smith CIE
Conference publication: VOX SANGUINIS. 2013;105:143
RANDOM OCCURRENCE OF AGGREGATES IN NEWLY PRODUCED PLATELET UNITS ARE RELATED TO HIGHER ACTIVATION AND ACCUMULATED RELEASE OF THE IMMUNOMODULATORY FACTORS SCD40 L AND RANTES
Sandgren PJK; Meinke S; Eckert E; Taune-Wikman A; Hoglund P
Preprint: NATURE PRECEDINGS.
The activating receptors 2B4 and NTB-A, but not CRACC are subject to ligand-induced down-regulation on human natural killer cells
Meinke S; Böhm C; Durlanik S; Watzl C

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