Stefanie Prast-Nielsen

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Docent i medicinsk mikrobiologi
Senior forskningsspecialist i multiomics, maskininlärning och dataintegration vid Centre for Translational Microbiome Research
Doktor i Medicinsk biokemi
För mer information, vänligen besök den engelska versionen av webbplatsen.

Artiklar

Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2024;59(6):674-682
Plasma bile acids in association with Crohn's disease
Kiasat A; Prast-Nielsen S; Rautiainen S; Engstrand L; Andersson F; Lindberg J; Schuppe-Koistinen I; Granstrom AL; Gustafsson UO
Article: BRAIN BEHAVIOR AND IMMUNITY. 2024;117:298-309
Differences in the gut microbiome of young adults with schizophrenia spectrum disorder: using machine learning to distinguish cases from controls
Stiernborg M; Prast-Nielsen S; Melas PA; Skott M; Millischer V; Boulund F; Forsell Y; Lavebratt C
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2023;58(11):1246-1252
Evaluation of plasma Short chain fatty acid levels as markers for Inflammatory bowel disease
Kiasat A; Rautiainen S; Prast-Nielsen S; Engstrand L; Schuppe-Koistinen I; Gustafsson UOO; Granstrom AL
Article: JOURNAL OF CROHNS & COLITIS. 2023;17(3):418-432
Mucosal and Plasma Metabolomes in New-onset Paediatric Inflammatory Bowel Disease: Correlations with Disease Characteristics and Plasma Inflammation Protein Markers
Nystrom N; Prast-Nielsen S; Correia M; Globisch D; Engstrand L; Schuppe-Koistinen I; Halfvarsond J
Article: EBIOMEDICINE. 2022;80:104061
Higher levels of Bifidobacteria and tumor necrosis factor in children with drug-resistant epilepsy are associated with anti-seizure response to the ketogenic diet
Dahlin M; Singleton SS; David JA; Basuchoudhary A; Wickstrom R; Mazumder R; Prast-Nielsen S
Article: JOURNAL OF DERMATOLOGICAL SCIENCE. 2022;106(3):132-140
Influence of FLG loss-of-function mutations in host-microbe interactions during atopic skin inflammation
Olah P; Szlavicz E; Kuchner M; Nemmer J; Zeeuwen P; Lefevre-Utile A; Fyhrquist N; Prast-Nielsen S; Skoog T; Serra A; Rodriguez E; Raap U; Meller S; Gyulai R; Hupe P; Kere J; Levi-Schaffer F; Tsoka S; Alexander H; Nestle FO; Schroeder JM; Weidinger S; van den Bogaard E; Soumelis V; Greco D; Barker J; Lauerma A; Ranki A; Andersson B; Alenius H; Homey B
Article: ALLERGY. 2022;77(5):1486-1498
Transcriptome-based identification of novel endotypes in adult atopic dermatitis
Lefevre-Utile A; Saichi M; Olah P; Delord M; Homey B; Soumelis V
Article: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2021;111:313-321
Alterations of gut microbiota in patients with active pulmonary tuberculosis in China: a pilot study
Shi W; Hu Y; Ning Z; Xia F; Wu M; Hu YOO; Chen C; Prast-Nielsen S; Xu B
Article: BMC PULMONARY MEDICINE. 2019;19(1):211
Longitudinal profiling of gut microbiome among tuberculosis patients under anti-tuberculosis treatment in China: protocol of a prospective cohort study
Shi W; Hu Y; Zheng X; Ning Z; Wu M; Xia F; Prast-Nielsen S; Hu YOO; Xu B
Article: NATURE COMMUNICATIONS. 2019;10(1):4703
Microbe-host interplay in atopic dermatitis and psoriasis
Fyhrquist N; Muirhead G; Prast-Nielsen S; Jeanmougin M; Olah P; Skoog T; Jules-Clement G; Feld M; Barrientos-Somarribas M; Sinkko H; van den Bogaard EH; Zeeuwen PLJM; Rikken G; Schalkwijk J; Niehues H; Daeubener W; Eller SK; Alexander H; Pennino D; Suomela S; Tessas I; Lybeck E; Baran AM; Darban H; Gangwar RS; Gerstel U; Jahn K; Karisola P; Yan L; Hansmann B; Katayama S; Meller S; Bylesjo M; Hupe P; Levi-Schaffer F; Greco D; Ranki A; Schroeder JM; Barker J; Kere J; Tsoka S; Lauerma A; Soumelis V; Nestle FO; Homeyl B; Andersson B; Alenius H
Journal article: BRITISH JOURNAL OF DERMATOLOGY. 2019;181(3):e72
Investigation of the skin microbiome
Prast‐Nielsen S; Tobin A; Adamzik K; Powles A; Hugerth LW; Sweeney C; Kirby B; Engstrand L; Fry L
Journal article: BRITISH JOURNAL OF DERMATOLOGY. 2019;181(3):e84
皮肤微生物组检查
Prast‐Nielsen S; Tobin A; Adamzik K; Powles A; Hugerth LW; Sweeney C; Kirby B; Engstrand L; Fry L
Article: BRITISH JOURNAL OF DERMATOLOGY. 2019;181(3):572-579
Investigation of the skin microbiome: swabs vs. biopsies
Prast-Nielsen S; Tobin A-M; Adamzik K; Powles A; Hugerth LW; Sweeney C; Kirby B; Engstrand L; Fry L
Article: NPJ BIOFILMS AND MICROBIOMES. 2019;5(1):5
The ketogenic diet influences taxonomic and functional composition of the gut microbiota in children with severe epilepsy
Lindefeldt M; Eng A; Darban H; Bjerkner A; Zetterstrom CK; Allander T; Andersson B; Borenstein E; Dahlin M; Prast-Nielsen S
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2011;50(9):1114-1123
Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay
Prast-Nielsen S; Dexheimer TS; Schultz L; Stafford WC; Cheng Q; Xu J; Jadhav A; Arner ESJ; Simeonov A
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2010;49(11):1765-1778
Noble metal targeting of thioredoxin reductase - covalent complexes with thioredoxin and thioredoxin-related protein of 14 kDa triggered by cisplatin
Prast-Nielsen S; Cebula M; Pader I; Arner ESJ
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2009;47(11):1661-1671
High levels of thioredoxin reductase 1 modulate drug-specific cytotoxic efficacy
Eriksson SE; Prast-Nielsen S; Flaberg E; Szekely L; Arner ESJ
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2009;52(20):6474-6483
Structure Mechanism Insights and the Role of Nitric Oxide Donation Guide the Development of Oxadiazole-2-Oxides as Therapeutic Agents against Schistosomiasis
Rai G; Sayed AA; Lea WA; Luecke HF; Chakrapani H; Prast-Nielsen S; Jadhav A; Leister W; Shen M; Inglese J; Austin CP; Keefer L; Arner ESJ; Simeonov A; Maloney DJ; Williams DL; Thomas CJ
Article: PLOS ONE. 2008;3(4):e1846
Cell Death by SecTRAPs: Thioredoxin Reductase as a Prooxidant Killer of Cells
Anestal K; Prast-Nielsen S; Cenas N; Arner ESJ
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(9):5593-5603
Interactions of nitroaromatic compounds with the mammalian selenoprotein thioredoxin reductase and the relation to induction of apoptosis in human cancer cells
Cenas N; Prast S; Nivinskas H; Sarlauskas J; Arnér ESJ
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005;327(3):774-779
Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release
Enoksson M; Fernandes AP; Prast S; Lillig CH; Hohngren A; Orrenius S
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Alla övriga publikationer

Preprint: BIORXIV. 2024
Profiling the intestinal microbiota, plasma bile acids and inflammation markers reveals novel associations in Crohn’s disease and Ulcerative colitis
Prast-Nielsen S; Granström AL; Kiasat A; Ahlström G; Edfeldt G; Rautiainen S; Boulund F; Andersson FO; Lindberg J; Schuppe-Koistinen I; Gustafsson UO; Engstrand L
Editorial comment: CELL REPORTS. 2023;42(12):113570
Preview Fecal transfers from children on the ketogenic diet mimic the anti-seizure effect in mice
Prast-Nielsen S
Letter: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022;206(12):1564-1567
Metatranscriptomics of Nasopharyngeal Microbiota and Host Distinguish between Pneumonia and Health
Nannapaneni P; Sundh J; Prast-Nielsen S; Rhedin S; Ortqvist A; Naucler P; Henriques-Normark B
Review: PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY. 2020;176:141-178
Bioinformatics and machine learning in gastrointestinal microbiome research and clinical application
Hopson LM; Singleton SS; David JA; Basuchoudhary A; Prast-Nielsen S; Klein P; Sen S; Mazumder R
Review: EBIOMEDICINE. 2019;44:741-746
The gut microbiome and epilepsy
Dahlin M; Prast-Nielsen S
Conference publication: HELICOBACTER. 2019;24
Study of the impact of Helicobacter pylori eradication treatments on the intestinal microbiota
McNicholl AG; Prast-Nielsen S; Andersen LP; Machado JC; Leja M; Alarcon T; Gasbarrini A; Megraud F; O'Morain C; Engstrand L; Gisbert JP
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2016;83(5):380-381
Microbe-host interplay in atopic dermatitis and psoriasis
Fyhrquist N; Andersson B; Kere J; Muirhead G; Prast-Nielsen S; Jeanmougin M; Barker J; Lauerma A; Homey B; Schroeder J; Soumelis V; Nestle F; Alenius H
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2011;1810(12):1262-1271
Thioredoxin glutathione reductase: Its role in redox biology and potential as a target for drugs against neglected diseases
Prast-Nielsen S; Huang H-H; Williams DL
Thesis / dissertation: 2009
Exploring thioredoxin reductase as an anticancer drug target
Prast-Nielsen, Stefanie
Conference publication: CANCER RESEARCH. 2009;69
Evaluation of plain platinum, palladium and gold salts as inhibitors of mammalian thioredoxin reductase: Implications for clinically used drugs and the development of new anticancer agents
Prast-Nielsen S; Arner E
Conference publication: FREE RADICAL RESEARCH. 2009;43:63
Drug-specific responses to cytotoxic agents mediated by high levels of thioredoxin reductase 1 in human A549 cancer cells
Eriksson S; Prast-Nielsen S; Flaberg E; Szekely L; Arner E

Anställningar

Senior Forskningsspecialist, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2023-2024

Examina och utbildning

Docent, Mikrobiologi inom det medicinska området, Karolinska Institutet, 2023
Medicine Doktorsexamen, Institutionen för medicinsk biokemi och biofysik, Karolinska Institutet, 2009

Om mig

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Anställningar

Examina och utbildning

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