Shao-Nian Yang

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: CELL REPORTS. 2018;24(4):922-934

Blocking Ca²⁺ Channel β₃ Subunit Reverses Diabetes

Lee K; Kim J; Kohler M; Yu J; Shi Y; Yang S-N; Ryu SH; Berggren P-O
Article: SCIENTIFIC REPORTS. 2016;6:23103

TLR3-/4-Priming Differentially Promotes Ca²⁺ Signaling and Cytokine Expression and Ca²⁺ -Dependently Augments Cytokine Release in hMSCs

Park KS; Kim SH; Das A; Yang S-N; Jung KH; Kim MK; Berggren P-O; Lee Y; Chai JC; Kim HJ; Chai YG
Article: BIOSCIENCE REPORTS. 2015;35(3):e00195

Photoactivation of hypericin decreases the viability of RINm5F insulinoma cells through reduction in JNK/ERK phosphorylation and elevation of caspase-9/caspase-3 cleavage and Bax-to-Bcl-2 ratio

Yi J; Yang X; Zheng L; Yang G; Sun L; Bao Y; Wu Y; Huang Y; Yu C; Yang S-N; Li Y
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2015;72(6):1197-1207

Ca_V1.2 and Ca_V1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum

Yang G; Shi Y; Yu J; Li Y; Yu L; Welling A; Hofmann F; Striessnig J; Juntti-Berggren L; Berggren P-O; Yang S-N
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2014;71(7):1289-1303

Apolipoprotein CIII hyperactivates β cell Ca_V1 channels through SR-BI/β1 integrin-dependent coactivation of PKA and Src

Shi Y; Yang G; Yu J; Yu L; Westenbroek R; Catterall WA; Juntti-Berggren L; Berggren P-O; Yang S-N
Article: DIABETOLOGIA. 2014;57(1):148-156

Differential regulation of mouse pancreatic islet insulin secretion and Smad proteins by activin ligands

Wu H; Mezghenna K; Marmol P; Guo T; Moliner A; Yang S-N; Berggren P-O; Ibanez CF
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(30):12183-12188

Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron

Yang S-N; Shi Y; Yang G; Li Y; Yu L; Shin O-H; Bacaj T; Suedhof TC; Yu J; Berggren P-O
Article: PANCREAS. 2012;41(1):15-21

Akt signals upstream of L-type calcium channels to optimize insulin secretion.

Cui X; Yang G; Pan M; Zhang X-N; Yang S-N
Article: EXPERIMENTAL DIABETES RESEARCH. 2011;2011:604989-7

Subthreshold α₂-adrenergic activation counteracts glucagon-like peptide-1 potentiation of glucose-stimulated insulin secretion.

Pan M; Yang G; Cui X; Yang S-N
Article: CELL METABOLISM. 2008;7(6):545-554

Glutamate is a positive autocrine signal for glucagon release

Cabrera O; Jacques-Silva MC; Speier S; Yang S-N; Kohler M; Fachado A; Vieira E; Zierath JR; Kibbey R; Berman DM; Kenyon NS; Ricordi C; Caicedo A; Berggren P-O
Article: SCIENCE. 2007;318(5854):1299-1302

Requirement of inositol pyrophosphates for full exocytotic capacity in pancreatic β cells

Illies C; Gromada J; Fiume R; Leibiger B; Yu J; Juhl K; Yang S-N; Barma DK; Falck JR; Saiardi A; Barker CJ; Berggren P-O
Article: CELL METABOLISM. 2007;6(3):217-228

Glucose recruits K_ATP channels via non-insulin-containing dense-core granules

Yang S-N; Wenna ND; Yu J; Yang G; Qiu H; Yu L; Juntti-Berggren L; Koher M; Berggren P-O
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(47):17020-17025

Transthyretin constitutes a functional component in pancreatic β-cell stimulus-secretion coupling

Refai E; Dekki N; Yang SN; Imreh G; Cabrera O; Yu LN; Yang G; Norgren S; Rössner SM; Inverardi L; Ricordi C; Olivecrona G; Andersson M; Jörnvall H; Berggren PO; Juntti-Berggren L
Article: CELL. 2004;119(2):273-284

Removal of Ca²⁺ channel β₃ Subunit enhances Ca²⁺ oscillation frequency and insulin exocytosis

Berggren PO; Yang SN; Murakami M; Efanov AM; Uhles S; Köhler M; Moede T; Fernström A; Appelskog LB; Aspinwall CA; Zaitsev SV; Larsson O; de Vargas LM; Fecher-Trost C; Weissgerber P; Ludwig A; Leibiger B; Juntti-Berggren L; Barker CJ; Gromada J; Freichel M; Leibiger IB; Flockerzi V
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(27):10090-10094

Apolipoprotein CIII promotes Ca²⁺-dependent β cell death in type 1 diabetes

Juntti-Berggren L; Refai E; Appelskog I; Andersson M; Imreh G; Dekki N; Uhles S; Yu L; Griffiths WJ; Zaitsev S; Leibiger I; Yang SN; Olivecrona G; Jörnvall H; Berggren PO
Article: MOLECULAR ENDOCRINOLOGY. 2004;18(7):1658-1669

Growth hormone promotes Ca²⁺-induced Ca²⁺ release in insulin-secreting cells by ryanodine receptor tyrosine phosphorylation

Zhang QM; Köhler M; Yang SN; Zhang F; Larsson O; Berggren PO
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(47):46210-46218

Cytosolic multiple inositol polyphosphate phosphatase in the regulation of cytoplasmic free Ca²⁺ concentration

Yu J; Leibiger B; Yang SN; Caffery JJ; Shears SB; Leibiger IB; Barker CJ; Berggren PO
Article: DEVELOPMENTAL CELL. 2003;5(1):73-83

Suppression of β cell energy metabolism and insulin release by PGC-1α

Yoon JC; Xu G; Deeney JT; Yang SN; Rhee J; Puigserver P; Levens AR; Yang RJ; Zhang CY; Lowell BB; Berggren PO; Newgard CB; Bonner-Weir S; Weir G; Spiegelman BM
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2003;100(9):5187-5192

Phosphatidylinositol 4-kinase serves as a metabolic sensor and regulates priming of secretory granules in pancreatic β cells

Olsen HL; Hoy M; Zhang W; Bertorello AM; Bokvist K; Capito K; Efanov AM; Meister B; Thams P; Yang SN; Rorsman P; Berggren PO; Gromada J
Article: DIABETES. 2002;51(5):1425-1436

Modulation of L-type Ca²⁺ channels by distinct domains within SNAP-25

Ji JZ; Yang SN; Huang XH; Li XD; Shen L; Diamant N; Berggren PO; Gaisano HY
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(36):34199-34205

Cyclin-dependent kinase 5 promotes insulin exocytosis

Lilja L; Yang SN; Webb DL; Juntti-Berggren L; Berggren PO; Bark C
Article: FASEB JOURNAL. 2001;15(10):1753-1763

Inositol hexakisphosphate increases L-type Ca²⁺ channel activity by stimulation of adenylyl cyclase

Yang SN; Yu J; Mayr GW; Hofmann F; Larsson O; Berggren PO
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(52):41521-41527

Munc-18 associates with syntaxin and serves as a negative regulator of exocytosis in the pancreatic β-cell

Zhang W; Efanov A; Yang SN; Fried G; Kölare S; Brown H; Zaitsev S; Berggren PO; Meister B
Article: DIABETES. 2000;49(3):383-391

Synaptotagmin III isoform is compartmentalized in pancreatic β-cells and has a functional role in exocytosis

Brown H; Meister B; Deeney J; Corkey BE; Yang SN; Larsson O; Rhodes CJ; Seino S; Berggren PO; Fried G
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1999;96(18):10164-10169

Syntaxin 1 interacts with the L_D subtype of voltage-gated Ca²⁺ channels in pancreatic β cells

Yang SN; Larsson O; Bränström R; Bertorello AM; Leibiger B; Leibiger IB; Moede T; Köhler M; Meister B; Berggren PO
Article: JOURNAL OF NEUROPHYSIOLOGY. 1999;81(2):781-787

Selective induction of LTP and LTD by postsynaptic [Ca2+]i elevation.

Yang SN; Tang YG; Zucker RS
Article: EMBO JOURNAL. 1998;17(17):5048-5058

Cysteine string protein (CSP) is an insulin secretory granule-associated protein regulating β-cell exocytosis

Brown H; Larsson O; Bränström R; Yang SN; Leibiger B; Leibiger I; Fried G; Moede T; Deeney JT; Brown GR; Jacobsson G; Rhodes CJ; Braun JEA; Scheller RH; Corkey BE; Berggren PO; Meister B
Article: NEUROSCIENCE. 1997;81(2):503-515

Localization of angiotensin II AT(1) receptor-like immunoreactivity in catecholaminergic neurons of the rat medulla oblongata

Yang SN; Lippoldt A; Jansson A; Phillips MI; Ganten D; Fuxe K
Article: NEUROSCIENCE. 1997;78(3):803-813

Increased potency of neuropeptide Y to antagonize alpha(2)-adrenoceptor function in the nucleus tractus solitarii of the spontaneously hypertensive rat

Yang SN; Fior DR; Hansson AC; Cintra A; Castellano M; Ganten U; Ganten D; Agnati LF; Fuxe K
Article: NEUROREPORT. 1996;7(15-17):2701-2705

The non-peptide neuropeptide Y Y-1 receptor antagonist BIBP3226 blocks the [Leu(31),Pro(34)]neuropeptide Y-induced modulation of alpha(2)-adrenoceptors in the nucleus tractus solitarii of the rat

Yang SN; Finnman UB; Fuxe K
Article: NEUROSCIENCE. 1996;73(2):519-530

Localization of neuropeptide Y Y-1 receptor-like immunoreactivity in catecholaminergic neurons of the rat medulla oblongata

Yang SN; Bunnemann B; Cintra A; Fuxe K
Article: NEUROSCIENCE. 1995;68(3):729-736

REDUCTION OF DOPAMINE D-2 RECEPTOR TRANSDUCTION BY ACTIVATION OF ADENOSINE A(2A) RECEPTORS IN STABLY A(2A)/D-2 (LONG-FORM) RECEPTOR CO-TRANSFECTED MOUSE FIBROBLAST CELL-LINES - STUDIES ON INTRACELLULAR CALCIUM LEVELS

YANG SN; DASGUPTA S; LLEDO PM; VINCENT JD; FUXE K
Article: BRAIN RESEARCH. 1995;679(1):168-177

EVIDENCE FOR A DIFFERENTIAL MODULATION OF THE ALPHA-2-ADRENOCEPTORS BY ANGIOTENSIN-II IN THE NUCLEUS-TRACTUS-SOLITARII OF THE SPONTANEOUSLY HYPERTENSIVE AND THE WISTAR-KYOTO NORMOTENSIVE RATS

FIOR DR; YANG SN; GANTEN U; GANTEN D; FUXE K
Article: NEUROREPORT. 1995;6(2):384-388

COUNTERACTION OF NPY-INDUCED C-FOS EXPRESSION IN THE NUCLEUS-TRACTUS-SOLITARII BY ALPHA(2) RECEPTOR AGONISTS

YANG SN; BJELKE B; NARVAEZ JA; CINTRA A; AGNATI LF; FUXE K
Visa fler

Alla övriga publikationer

Review: PHARMACOLOGY & THERAPEUTICS. 2019;197:103-121

The eye as a novel imaging site in diabetes research

Yang S-N; Berggren P-O
Review: CELLULAR AND MOLECULAR LIFE SCIENCES. 2014;71(21):4149-4177

Ionic mechanisms in pancreatic β cell signaling

Yang S-N; Shi Y; Yang G; Li Y; Yu J; Berggren P-O
Corrigendum: EXPERIMENTAL DIABETES RESEARCH. 2011;:319202-1

Subthreshold α₂-Adrenergic Activation Counteracts Glucagon-Like Peptide-1 Potentiation of Glucose-Stimulated Insulin Secretion (vol 2011, 604989, 2011)

Pan M; Yang G; Cui X; Yang S-N
Review: ENDOCRINE REVIEWS. 2006;27(6):621-676

The role of voltage-gated calcium channels in pancreatic β-cell physiology and pathophysiology

Yang S-N; Berggren P-O
Editorial comment: JOURNAL OF CLINICAL INVESTIGATION. 2005;115(1):16-20

Ca_v2.3 channel and PKCλ:: new players in insulin secretion

Yang SN; Berggren PO
Review: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2005;288(1):E16-E28

β-cell Ca_V channel regulation in physiology and pathophysiology

Yang SN; Berggren PO
Published conference paper: DIABETES. 2001;50:S77-S81

Effects of serum from patients with type 1 diabetes on primary cerebellar granule cells

Chandra J; Yang SN; Köhler M; Zaitsev S; Juntti-Berggren L; Berggren PO; Zhivotovsky B; Orrenius S
Published conference paper: DIABETES. 2001;50:S70-S76

Imidazoline compounds protect against interleukin 1β-induced β-cell apoptosis

Zaitsev SV; Appelskog IB; Kapelioukh IL; Yang SN; Köhler M; Efendic S; Berggren PO

Anställningar

Senior Forskningsspecialist, Molekylär medicin och kirurgi, Karolinska Institutet, 2022-

Examina och utbildning

Docent, Cellbiologi, Karolinska Institutet, 2006

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI