Sangram Nag

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Artiklar

Article: JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE. 2025;12(8):100302
Results of the first-in-human, randomized, double-blind, placebo-controlled, single- and multiple-ascending dose study of BIIB113 in healthy volunteers
Nery FC; Kaliszczak M; Suttle B; Jones L; Wu S; Xie J; Curiale G; Yesilalan E; Hirschhorn B; Wilkes D; Singh D; Bolin M; Nag S; Varrone A; Stenkrona P; Halldin C; Yachnin J; Arnold HM; Bullain S; Landen J; Gallagher D; Hering H
Article: JOURNAL OF NUCLEAR MEDICINE. 2025;:jnumed.125.269671
Imaging Proinflammatory Microglia in Parkinson Disease Using [11C]SMW139 PET: A Multicenter Study.
Rikken RM; van de Giessen E; Brumberg J; Aarnio R; Joling M; Forsberg Morén A; Kerstens V; Moein MM; Nag S; Halldin C; Fazio P; Roos DS; Berendse HW; Kassiou M; Wahlroos S; Haaparanta-Solin M; Oikonen V; Schuit RC; Boellaard R; Windhorst AD; Jacobs AH; Lammertsma AA; Rinne JO; Varrone A; Golla SSV
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2025;45(8):1606-1616
In vivo quantification of [¹¹C]BIO-1819578 in non-human primates, a novel radioligand for O-GlcNAcase
Bolin M; Nag S; Arakawa R; Varrone A; Farde L; Martarello L; Kaliszczak MA; Halldin C; Moren AF
Article: EJNMMI RESEARCH. 2025;15(1):71
Test-retest properties of [¹¹C]PXT012253 as a positron emission tomography (PET) radiotracer in healthy human brain: PET imaging of mGlu4
Stenkrona P; Arakawa R; Guo J; Bang-Andersen B; Nag S; Moein MM; Jia Z; Cselenyi Z; Halldin C; Varrone A
Article: SCIENCE TRANSLATIONAL MEDICINE. 2025;17(797):eadl1732
PET imaging of antisense oligonucleotide distribution in rat and nonhuman primate brains using click chemistry
Cook BE; Pickel TC; Nag S; Bolduc PN; Beshr R; Moren AF; Muste C; Boscutti G; Jiang D; Yuan L; Datta P; Ochniewicz P; Meynaq YK; Tang S-P; Plisson C; Amatruda M; Zhang Q; DuBois JM; Delavari A; Klein SK; Polyak I; Shoroye A; Girmay S; Halldin C; Martarello L; Peterson EA; Kaliszczak M
Article: MOLECULES. 2025;30(6):1356
Good Manufacturing Practice Validation and Radiation Dosimetry for the Clinical Application of a Novel α7-nAChR Radioligand: [¹¹C]KIn83
Jia Z; Bolin M; Moren AF; Datta P; Asem H; Agren H; Langstrom B; Nordberg A; Halldin C; Nag S
Journal article: ALZHEIMERS & DEMENTIA. 2024;20(Suppl 2):e086566
Pretargeted Imaging for In Vivo Assessment of ASO Therapy Delivery in Alzheimer’s Disease
Cook BE; Pickel TC; Amatruda M; Zhang Q; Nag S; Bolduc P; Beshr R; Morén AF; Muste C; Datta P; Ochniewicz P; Meynaq YK; DuBois JM; Klein SK; Halldin C; Passamonti L; Kaliszczak M
Journal article: ALZHEIMERS & DEMENTIA. 2024;20(Suppl 9):e093694
Pretargeted Imaging for In Vivo Assessment of ASO Therapy Delivery in Alzheimer’s Disease
Cook BE; Pickel TC; Amatruda M; Zhang Q; Nag S; Bolduc P; Beshr R; Morén AF; Muste C; Datta P; Ochniewicz P; Meynaq YK; DuBois JM; Klein SK; Halldin C; Passamonti L; Kaliszczak M
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2024;25(14):7870
Labeling of Bruton's Tyrosine Kinase (BTK) Inhibitor [¹¹C]BIO-2008846 in Three Different Positions and Measurement in NHP Using PET
Nag S; Datta P; Moren AF; Khani Y; Martarello L; Kaliszczak M; Halldin C
Article: ACS CHEMICAL NEUROSCIENCE. 2024;15(10):2018-2027
Exploring the Interactions between two Ligands, UCB-J and UCB-F, and Synaptic Vesicle Glycoprotein 2 Isoforms
Li J; Zou R; Varrone A; Nag S; Halldin C; Agren H
Article: JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2024;67(4):155-164
Automated radiosynthesis of mGluR5 PET tracer [¹⁸F]FPEB from aryl-chloro precursor and validation for clinical application
Jahan M; Amir A; Das A; Kihlstroem J; Nag S
Article: PHARMACEUTICALS. 2024;17(2):250
Advancements in Microfluidic Cassette-Based iMiDEV™ Technology for Production of L-[¹¹C]Methionine and [¹¹C]Choline
Mallapura H; Tanguy L; Mahfuz S; Bylund L; Langstrom B; Halldin C; Nag S
Article: MOLECULES. 2024;29(2):427
Synthesis of [¹¹C]BIIB104, an α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic-Acid-Positive Allosteric Modulator, and Evaluation of the Bio-Distribution in Non-Human Primate Brains Using Positron Emission Tomography
Nag S; Jia K; Arakawa R; Datta P; Scott D; Shaffer C; Moein MM; Hutchison M; Kaliszczak M; Halldin C
Article: EJNMMI RADIOPHARMACY AND CHEMISTRY. 2023;8(1):42
Microfluidic-based production of [⁶⁸Ga]Ga-FAPI-46 and [⁶⁸Ga]Ga-DOTA-TOC using the cassette-based iMiDEV™ microfluidic radiosynthesizer
Mallapura H; Ovdiichuk O; Jussing E; Thuy TA; Piatkowski C; Tanguy L; Collet-Defossez C; Langstrom B; Halldin C; Nag S
Journal article: NUCLEAR MEDICINE AND BIOLOGY. 2023;126:108545
P-073 Discovery of [18F]F-687-TCO: An Optimized Tracer for Pretargeted PET Imaging in the CNS
Cook B; Pickel T; Jiang D; Bolduc P; Nag S; Tang S-P; Nasr K; Boscutti G; Plisson C; Morén A; Ochniewicz P; Halldin C; Peterson E; Martarello L; Kaliszczak M
Journal article: JOURNAL OF NUCLEAR MEDICINE. 2023;64(10):1588-1593
Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain.
Cook BE; Nag S; Arakawa R; Lin EY-S; Stratman N; Guckian K; Hering H; Lulla M; Choi J; Salinas C; Genung NE; Morén AF; Bolin M; Boscutti G; Plisson C; Martarello L; Halldin C; Kaliszczak MA
Article: JOURNAL OF NUCLEAR MEDICINE. 2023;64(10):1588-1593
Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain
Cook BE; Nag S; Arakawa R; Lin EY-S; Stratman N; Guckian K; Hering H; Lulla M; Choi J; Salinas C; Genung NE; Moren AF; Bolin M; Boscutti G; Plisson C; Martarello L; Halldin C; Kaliszczak MA
Article: ACS CHEMICAL NEUROSCIENCE. 2023;14(17):3206-3211
PET Evaluation of the Novel F-18 Labeled Reversible Radioligand [¹⁸F]GEH200449 for Detection of Monoamine Oxidase-B in the Non-Human Primate Brain
Varnas K; Nag S; Halldin C; Farde L
Article: ACS CHEMICAL NEUROSCIENCE. 2023;14(14):2560-2568
Development of a Novel [¹¹C]CO-Labeled Positron Emission Tomography Radioligand [¹¹C]BIO-1819578 for the Detection of O-GlcNAcase Enzyme Activity
Nag S; Bolin M; Datta P; Arakawa R; Moren AF; Maynaq YK; Lin E; Genung N; Hering H; Guckian K; Martarello L; Kaliszczak M; Halldin C
Article: MOLECULES. 2023;28(12):4612
Characterization of a Novel M4 PAM PET Radioligand [11C]PF06885190 in Nonhuman Primates (NHP)
Nag S; Arakawa R; Jia Z; Lachapelle E; Zhang L; Maresca K; Chen L; Jahan M; Mccarthy T; Halldin C
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2023;43(2):258-268
Quantification of the purinergic P2X₇ receptor with [¹¹C]SMW139 improves through correction for brain-penetrating radiometabolites
Brumberg J; Aarnio R; Forsberg A; Marjamaki P; Kerstens V; Moein MM; Nag S; Wahlroos S; Kassiou M; Windhorst AD; Halldin C; Haaparanta-Solin M; Fazio P; Oikonen V; Rinne JO; Varrone A
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2023;66(1):641-656
Design and Evaluation of [18F]CHDI-650 as a Positron Emission Tomography Ligand to Image Mutant Huntingtin Aggregates
Liu L; Johnson PD; Prime ME; Khetarpal V; Brown CJ; Anzillotti L; Bertoglio D; Chen X; Coe S; Davis R; Dickie AP; Esposito S; Gadouleau E; Giles PR; Greenaway C; Haber J; Halldin C; Haller S; Hayes S; Herbst T; Herrmann F; Hessmann M; Hsai MM; Khani Y; Kotey A; Lembo A; Mangette JE; Marriner GA; Marston RW; Mills MR; Monteagudo E; Forsberg-Moren A; Nag S; Orsatti L; Sandiego C; Schaertl S; Sproston J; Staelens S; Tookey J; Turner PA; Vecchi A; Veneziano M; Munoz-Sanjuan I; Bard J; Dominguez C
Article: MOLECULES. 2022;27(24):8843
Production of [¹¹C]Carbon Labelled Flumazenil and L-Deprenyl Using the iMiDEV™ Automated Microfluidic Radiosynthesizer
Mallapura H; Tanguy L; Langstrom B; Le Meunier L; Halldin C; Nag S
Article: JOURNAL OF NUCLEAR MEDICINE. 2022;63(12):1919-1924
First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B
Wakabayashi Y; Stenkrona P; Arakawa R; Yan X; Van Buskirk MG; Jenkins MD; Santamaria JAM; Maresca KP; Takano A; Liow J-S; Chappie TA; Varrone A; Nag S; Zhang L; Hughes ZA; Schmidt CJ; Doran SD; Mannes A; Zanotti-Fregonara P; Ooms M; Morse CL; Zoghbi SS; Halldin C; Pike VW; Innis RB
Journal article: ACS CHEMICAL NEUROSCIENCE. 2022;13(19):2932-2933
Development of ¹¹C-Labeled ASEM Analogues for Detection of Neuronal Nicotinic Acetylcholine Receptors (α7-nAChR) (vol 13, pg 352, 2022)
Nag S; Miranda-Azpiazu P; Jia Z; Datta P; Arakawa R; Moein M; Yang Z; Tu Y; Lemoine L; Agren H; Nordberg A; Langstrom B; Halldin C
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2022;76(7-8):e22235
Decreased 5-HT_1A binding in mild Alzheimer's disease-A positron emission tomography study
Mattsson P; Cselenyi Z; Andree B; Borg J; Nag S; Halldin C; Farde L
Journal article: NUCLEAR MEDICINE AND BIOLOGY. 2022;108:s26
O-37 Synthesis and biological evaluation of a novel radioligand [11C] BIO-1790735 for detection of O-GlcNAcase (OGA) enzyme activity
Nag S; Arakawa R; Datta P; Morén A; Varrone A; Moein MM; Bolin M; Lin E; Genung N; Martarello L; Kaliszczak M; Halldin C
Journal article: NUCLEAR MEDICINE AND BIOLOGY. 2022;108:s122-s123
P-133 Automated radiolabeling of [68Ga]Ga-DOTATOC using the iMiDEV™ automated microfluidic radiosynthesizer
Chandrashekara HK; Tran T; Jussing E; Tanguy L; Långström B; Le Meunier L; Halldin C; Nag S
Article: EJNMMI RESEARCH. 2022;12(1):13
Target occupancy study and whole-body dosimetry with a MAGL PET ligand [¹¹C]PF-06809247 in non-human primates
Arakawa R; Takano A; Nag S; Jia Z; Amini N; Maresca KP; Zhang L; Keliher EJ; Butler CR; Piro JR; Samad TA; Smith D; Nason D; O'Neil S; Trapa P; Fonseca KR; Litchfield J; McCarthy T; Carson RE; Halldin C
Article: ACS CHEMICAL NEUROSCIENCE. 2022;13(3):352-362
Development of C-11-Labeled ASEM Analogues for the Detection of Neuronal Nicotinic Acetylcholine Receptors (alpha 7-nAChR)
Nag S; Miranda-Azpiazu P; Jia Z; Datta P; Arakawa R; Moein MM; Yang Z; Tu Y; Lemoine L; Agren H; Nordberg A; Langstrom B; Halldin C
Article: ACS CHEMICAL NEUROSCIENCE. 2021;12(24):4580-4586
PET Imaging of VMAT2 with the Novel Radioligand [¹⁸F]FE-DTBZ-d4 in Nonhuman Primates: Comparison with [¹¹C]DTBZ and [¹⁸F]FE-DTBZ
Nag S; Jahan M; Toth M; Nakao R; Varrone A; Halldin C
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2021;64(16):12003-12021
[¹¹C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins
Liu L; Johnson PD; Prime ME; Khetarpal V; Lee MR; Brown CJ; Chen X; Clark-Frew D; Coe S; Conlon M; Davis R; Ensor S; Esposito S; Moren AF; Gai X; Green S; Greenaway C; Haber J; Halldin C; Hayes S; Herbst T; Herrmann F; He-mann M; Hsai MM; Kotey A; Mangette JE; Mills MR; Monteagudo E; Nag S; Nibbio M; Orsatti L; Schaertl S; Scheich C; Sproston J; Stepanov V; Varnas K; Varrone A; Wityak J; Mrzljak L; Munoz-Sanjuan I; Bard JA; Dominguez C
Article: LAB ON A CHIP. 2021;21(11):2272-2282
Implementation of iMiDEV™, a new fully automated microfluidic platform for radiopharmaceutical production
Ovdiichuk O; Mallapura H; Pineda F; Hourtane V; Langstrom B; Halldin C; Nag S; Maskali F; Karcher G; Collet C
Article: ACS CHEMICAL NEUROSCIENCE. 2020;11(24):4398-4404
Synthesis and Autoradiography of Novel F-18 Labeled Reversible Radioligands for Detection of Monoamine Oxidase B
Nag S; Jia Z; Svedberg M; Jackson A; Ahmad R; Luthra S; Varnas K; Farde L; Halldin C
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2020;47(10):2429-2439
PET imaging of beta-secretase 1 in the human brain: radiation dosimetry, quantification, and test-retest examination of [¹⁸F]PF-06684511
Arakawa R; Takano A; Stenkrona P; Stepanov V; Nag S; Jahan M; Gryback P; Bolin M; Chen L; Zhang L; He P; Villalobos A; McCarthy TJ; Halldin C; Varrone A
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2020;63(15):8608-8633
Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand
Liu L; Prime ME; Lee MR; Khetarpal V; Brown CJ; Johnson PD; Miranda-Azpiazu P; Chen X; Clark-Frew D; Coe S; Davis R; Dickie A; Ebneth A; Esposito S; Gadouleau E; Gai X; Galan S; Green S; Greenaway C; Giles P; Halldin C; Hayes S; Herbst T; Herrmann F; Hessmann M; Jia Z; Kiselyov A; Kotey A; Krulle T; Mangette JE; Marston RW; Menta S; Mills MR; Monteagudo E; Nag S; Nibbio M; Orsatti L; Schaertl S; Scheich C; Sproston J; Stepanov V; Svedberg M; Takano A; Taylor M; Thomas W; Toth M; Vaidya D; Vanras K; Weddell D; Wigginton I; Wityak J; Mrzljak L; Munoz-Sanjuan I; Bard JA; Dominguez C
Article: ACS CHEMICAL NEUROSCIENCE. 2020;11(7):1048-1057
Synthesis, Biodistribution, and Radiation Dosimetry of a Novel mGluR5 Radioligand: ¹⁸F-AZD9272
Nag S; Varnas K; Arakawa R; Jahan M; Schou M; Farde L; Halldin C
Article: MOVEMENT DISORDERS. 2020;35(4):606-615
PET molecular imaging of phosphodiesterase 10A: An early biomarker of Huntington's disease progression
Fazio P; Fitzer-Attas CJ; Mrzljak L; Bronzova J; Nag S; Warner JH; Landwehrmeyer B; Al-Tawil N; Halldin C; Forsberg A; Ware J; Dilda V; Wood A; Sampaio C; Varrone A; Svenningsson P; Paucar M; Sundblom J; Nyholm D; Widner H; Heiberg A; Frich J; Nielsen J; Hjermind L; Roos R
Article: NEUROPHARMACOLOGY. 2020;162:107809
The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans
Varnas K; Cselenyi Z; Arakawa R; Nag S; Stepanov V; Moein MM; Johnstrom P; Kingston L; Elmore CS; Halldin C; Farde L
Article: EJNMMI RESEARCH. 2019;9(1):100
Potential for imaging the high-affinity state of the 5-HT_1B receptor: a comparison of three PET radioligands with differing intrinsic activity
Lindberg A; Arakawa R; Nogami T; Nag S; Schou M; Elmore CS; Farde L; Pike VW; Halldin C
Article: NUCLEAR MEDICINE AND BIOLOGY. 2019;78-79:11-16
Development of a ¹⁸F-labeled PET radioligand for imaging 5-HT_1B receptors: [¹⁸F]AZ10419096
Lindberg A; Nag S; Schou M; Arakawa R; Nogami T; Moein MM; Elmore CS; Pike VW; Halldin C
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2019;62(18):8532-8543
Identification and Development of an Irreversible Monoacylglycerol Lipase (MAGL) Positron Emission Tomography (PET) Radioligand with High Specificity
Zhang L; Butler CR; Maresca KP; Takano A; Nag S; Jia Z; Arakawa R; Piro JR; Samad T; Smith DL; Nason DM; O'Neil S; McAllister L; Schildknegt K; Trapa P; McCarthy TJ; Villalobos A; Halldin C
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2019;29(16):2270-2274
Synthesis and biological evaluation of [¹⁸F]fluorovinpocetine, a potential PET radioligand for TSPO imaging
Nag S; Krasikova R; Airaksinen AJ; Arakawa R; Petukhovd M; Gulyas B
Article: MALARIA JOURNAL. 2019;18(1):252
Proof of concept: used malaria rapid diagnostic tests applied for parallel sequencing for surveillance of molecular markers of anti-malarial resistance in Bissau, Guinea-Bissau during 2014-2017
Nag S; Ursing J; Rodrigues A; Crespo M; Krogsgaard C; Lund O; Aarestrup FM; Alifrangis M; Kofoed P-E
Journal article: ALZHEIMERS & DEMENTIA. 2019;15(7S_Part_31):p1630
O5‐06‐06: LIGANDS OF THE CORE ACETYLCHOLINE BIOSYNTHESIZING ENZYME, CHOLINE ACETYLTRANSFERASE, AS NOVEL AND POTENTIAL THERAPEUTIC AGENTS AND IN VIVO PET TRACERS FOR EARLY DIAGNOSIS OF ALZHEIMER'S DISEASE
Darreh-Shori T; Kumar R; Kumar A; Murumkar P; Nag S; Jia Z; Arakawa R; Leuzy A; Lemoine L; Nordberg A; Yadav MR; Halldin C; Långström B
Article: JOURNAL OF NUCLEAR MEDICINE. 2019;60(7):992-997
Quantitative Analysis of ¹⁸F-PF-06684511, a Novel PET Radioligand for Selective β-Secretase 1 Imaging, in Nonhuman Primate Brain
Takano A; Chen L; Nag S; Brodney MA; Arakawa R; Chang C; Amini N; Doran SD; Dutra JK; McCarthy TJ; Nolan CE; O'Neill BT; Villalobos A; Zhang L; Halldin C
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2019;29(13):1624-1627
Synthesis and preclinical evaluation of [¹⁸F]FSL25.1188, a reversible PET radioligand for monoamine oxidase-B
Dahl K; Bernard-Gauthier V; Nag S; Varnas K; Narayanaswami V; Moein MM; Arakawa R; Vasdev N; Halldin C
Article: MOLECULAR IMAGING AND BIOLOGY. 2019;21(3):500-508
Characterization of [¹¹C]PXT012253 as a PET Radioligand for mGlu₄ Allosteric Modulators in Nonhuman Primates
Takano A; Nag S; Jia Z; Jahan M; Forsberg A; Arakawa R; Gryback P; Duvey G; Halldin C; Charvin D
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2019;22(4):278-285
Venlafaxine ER Blocks the Norepinephrine Transporter in the Brain of Patients with Major Depressive Disorder: a PET Study Using [¹⁸F]FMeNER-D₂
Arakawa R; Stenkrona P; Takano A; Svensson J; Andersson M; Nag S; Asami Y; Hirano Y; Halldin C; Lundberg J
Article: NUCLEAR MEDICINE AND BIOLOGY. 2019;70:1-13
Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT_1β receptors
Lindberg A; Lu S; Nag S; Schou M; Liow J-S; Zoghbi SS; Frankland MP; Gladding RL; Morse CL; Takano A; Amini N; Elmore CS; Lee YS; Innis RB; Halldin C; Pike VW
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2018;61(8):3296-3308
Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain
Zhang L; Chen L; Dutra JK; Beck EM; Nag S; Takano A; Amini N; Arakawa R; Brodney MA; Buzon LM; Doran SD; Lanyon LF; McCarthy TJ; Bales KR; Nolan CE; O'Neill BT; Schildknegt K; Halldin C; Villalobos A
Article: MALARIA JOURNAL. 2018;17(1):91
Direct whole-genome sequencing of Plasmodium falciparum specimens from dried erythrocyte spots
Nag S; Kofoed P-E; Ursing J; Lemvigh CK; Allesoe RL; Rodrigues A; Svendsen CA; Jensen JD; Alifrangis M; Lund O; Aarestrup FM
Article: ALZHEIMERS RESEARCH & THERAPY. 2017;9(1):96
Comparative binding properties of the tau PET tracers THK5117, THK5351, PBB3, and T807 in postmortem Alzheimer brains
Lemoine L; Gillberg P-G; Svedberg M; Stepanov V; Jia Z; Huang J; Nag S; Tian H; Ghetti B; Okamura N; Higuchi M; Halldin C; Nordberg A
Article: NUCLEAR MEDICINE AND BIOLOGY. 2017;54:34-40
[¹¹C]AZ10419096-a full antagonist PET radioligand for imaging brain 5-HT_1B receptors
Lindberg A; Nag S; Schou M; Takano A; Matsumoto J; Amini N; Elmore CS; Farde L; Pike VW; Haildin C
Journal article: ALZHEIMERS & DEMENTIA. 2017;13(7S_Part_3):p139-p140
[IC‐P‐189]: COMPARISON OF BINDING PROPERTIES OF THK5117, THK5351, PBB3 AND T807 IN AUTOPSIES OF ALZHEIMER DISEASE CASES
Lemoine L; Gillberg P; Svedberg M; Stepanov V; Nag S; Tian H; Higuchi M; Halldin C; Nordberg A
Journal article: ALZHEIMERS & DEMENTIA. 2017;13(7S_Part_28):p1390
[P4–274]: COMPARISON OF BINDING PROPERTIES OF THK5117, THK5351, PBB3 AND T807 IN AUTOPSIES OF ALZHEIMER DISEASE CASES
Lemoine L; Gillberg P; Svedberg M; Stepanov V; Nag S; Tian H; Higuchi M; Halldin C; Nordberg A
Article: EJNMMI RESEARCH. 2017;7(1):54
Test-retest reproducibility of [¹¹C]-Ldeprenyl-D2 binding to MAO-B in the human brain
Arakawa R; Stenkrona P; Takano A; Nag S; Maior RS; Halldin C
Article: SCIENTIFIC REPORTS. 2017;7(1):2398
High throughput resistance profiling of Plasmodium falciparum infections based on custom dual indexing and Illumina next generation sequencing-technology
Nag S; Dalgaard MD; Kofoed P-E; Ursing J; Crespo M; Andersen LO; Aarestrup FM; Lund O; Alifrangis M
Article: NEUROIMAGE. 2017;152:330-339
Patterns of age related changes for phosphodiesterase type-10A in comparison with dopamine D_2/3 receptors and sub-cortical volumes in the human basal ganglia: A PET study with ¹⁸F-MNI-659 and ¹¹C-raelopride with correction for partial volume effect
Fazio P; Schain M; Mrzljak L; Amini N; Nag S; Al-Tawil N; Fitzer-Attas CJ; Bronzova J; Landwehrmeyer B; Sampaio C; Halldin C; Varrone A
Article: NEUROPHARMACOLOGY. 2017;117:171-181
In vivo measurement of PDE10A enzyme occupancy by positron emission tomography (PET) following single oral dose administration of PF-02545920 in healthy male subjects
Delnomdedieu M; Forsberg A; Ogden A; Fazio P; Yu C-R; Stenkrona P; Duvvuri S; David W; Al-Tawil N; Vitolo OV; Amini N; Nag S; Halldin C; Varrone A
Article: JOURNAL OF NUCLEAR MEDICINE. 2017;58(4):617-622
Longitudinal Small-Animal PET Imaging of the zQ175 Mouse Model of Huntington Disease Shows In Vivo Changes of Molecular Targets in the Striatum and Cerebral Cortex
Haggkvist J; Toth M; Tari L; Varnas K; Svedberg M; Forsberg A; Nag S; Dominguez C; Munoz-Sanjuan I; Bard J; Wityak J; Varrone A; Halldin C; Mrzljak L
Article: JOURNAL OF NUCLEAR MEDICINE. 2016;57(2):315-320
In Vivo and In Vitro Characterization of a Novel MAO-B Inhibitor Radioligand, ¹⁸F-Labeled Deuterated Fluorodeprenyl
Nag S; Fazio P; Lehmann L; Kettschau G; Heinrich T; Thiele A; Svedberg M; Amini N; Leesch S; Catafau AM; Hannestad J; Varrone A; Halldin C
Article: JOURNAL OF NUCLEAR MEDICINE. 2015;56(5):714-720
Quantitative Analysis of ¹⁸F-(E)-N-(3-Iodoprop-2-Enyl)-2β-Carbofluoroethoxy-3β-(4′-Methyl-Phenyl) Nortropane Binding to the Dopamine Transporter in Parkinson Disease
Fazio P; Svenningsson P; Forsberg A; Jonsson EG; Amini N; Nakao R; Nag S; Halldin C; Farde L; Varrone A
Article: NUCLEAR MEDICINE AND BIOLOGY. 2015;42(4):387-394
Synthesis and biological evaluation of [¹¹C]AZ12504948; a novel tracer for imaging of glucokinase in pancreas and liver
Jahan M; Johnstrom P; Nag S; Takano A; Korsgren O; Johansson L; Halldin C; Eriksson O
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2015;42(3):438-446
Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [¹⁸F]FEMPA in Alzheimer's disease patients and control subjects
Varrone A; Oikonen V; Forsberg A; Joutsa J; Takano A; Solin O; Haaparanta-Solin M; Nag S; Nakao R; Al-Tawil N; Wells LA; Rabiner EA; Valencia R; Schultze-Mosgau M; Thiele A; Vollmer S; Dyrks T; Lehmann L; Heinrich T; Hoffmann A; Nordberg A; Halldin C; Rinne JO
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2013;21(21):6634-6641
Development of a novel fluorine-18 labeled deuterated fluororasagiline ([¹⁸F]fluororasagiline-D₂) radioligand for PET studies of monoamino oxidase B (MAO-B)
Nag S; Lehmann L; Kettschau G; Toth M; Heinrich T; Thiele A; Varrone A; Halldin C
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2013;40(6):921-931
In vivo imaging of the ¹⁸-kDa translocator protein (TSPO) with [¹⁸F]FEDAA1106 and PET does not show increased binding in Alzheimer's disease patients
Varrone A; Mattsson P; Forsberg A; Takano A; Nag S; Gulyas B; Borg J; Boellaard R; Al-Tawil N; Eriksdotter M; Zimmermann T; Schultze-Mosgau M; Thiele A; Hoffmann A; Lammertsma AA; Halldin C
Article: EJNMMI RESEARCH. 2013;3(1):30
In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [¹⁸F]FEDAA1106
Takano A; Piehl F; Hillert J; Varrone A; Nag S; Gulyas B; Stenkrona P; Villemagne VL; Rowe CC; Macdonell R; Al Tawil N; Kucinski T; Zimmermann T; Schultze-Mosgau M; Thiele A; Hoffmann A; Halldin C
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2013;21(1):186-195
Synthesis and biological evaluation of novel propargyl amines as potential fluorine-18 labeled radioligands for detection of MAO-B activity
Nag S; Kettschau G; Heinrich T; Varrone A; Lehmann L; Gulyas B; Thiele A; Keller E; Halldin C
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2012;20(9):3065-3071
Synthesis and evaluation of [¹⁸F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B)
Nag S; Lehmann L; Kettschau G; Heinrich T; Thiele A; Varrone A; Gulyas B; Halldin C
Article: NUCLEAR MEDICINE AND BIOLOGY. 2012;39(3):315-323
Fluorine-18 labeling of three novel D-peptides by conjugation with N-succinimidyl-4-[¹⁸F]fluorobenzoate and preliminary examination by postmortem whole-hemisphere human brain autoradiography
Jahan M; Nag S; Krasikova R; Weber U; Muhs A; Pfeifer A; Spenger C; Willbold D; Gulyas B; Halldin C
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2012;66(4):323-330
In vivo evaluation in cynomolgus monkey brain and metabolism of [18F]fluorodeprenyl: A new MAO-B pet radioligand
Nag S; Varrone A; Toth M; Thiele A; Kettschau G; Heinrich T; Lehmann L; Halldin C
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2011;54(20):7023-7029
Synthesis of Three Novel Fluorine-18 Labeled Analogues of L-Deprenyl for Positron Emission Tomography (PET) studies of Monoamine Oxidase B (MAO-B)
Nag S; Lehmann L; Heinrich T; Thiele A; Kettschau G; Nakao R; Gulyas B; Halldin C
Article: PSYCHOPHARMACOLOGY. 2011;216(2):279-286
NET occupancy by clomipramine and its active metabolite, desmethylclomipramine, in non-human primates in vivo
Takano A; Nag S; Gulyas B; Halldin C; Farde L
Article: NEUROCHEMISTRY INTERNATIONAL. 2011;58(1):60-68
Activated MAO-B in the brain of Alzheimer patients, demonstrated by [¹¹C]-L-deprenyl using whole hemisphere autoradiography
Gulyas B; Pavlova E; Kasa P; Gulya K; Bakota L; Varszegi S; Keller E; Horvath MC; Nag S; Hermecz I; Magyar K; Halldin C
Article: NEUROCHEMISTRY INTERNATIONAL. 2010;56(6-7):789-798
The norepinephrine transporter (NET) radioligand (S,S)-[¹⁸F]FMeNER-D₂ shows significant decreases in NET density in the human brain in Alzheimer's disease: A post-mortem autoradiographic study
Gulyas B; Brockschnieder D; Nag S; Pavlova E; Kasa P; Beliczai Z; Legradi A; Gulya K; Thiele A; Dyrks T; Halldin C
Article: APPLIED RADIATION AND ISOTOPES. 2009;67(1):73-78
A fully automated one-pot synthesis of [carbonyl-¹¹C]WAY-100635 for clinical PET applications
Krasikova RN; Andersson J; Truong P; Nag S; Shchukin EV; Halldin C
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2008;16(13):6467-6473
[¹¹C]cyclopropyl-FLB 457:: A PET radioligand for low densities of dopamine D₂ receptors
Airaksinen AJ; Nag S; Finnema SJ; Mukherjee J; Chattopadhyay S; Gulyas B; Farde L; Halldin C
Article: DIABETOLOGIA. 2004;47(Suppl 1):a1-a464
Special pre-manufactured footwear with insoles can prevent ulceration in diabetic patients with diabetic foot syndrome by pressure reduction. A prospective randomised study
Veitenhansl M; Stegner K; Hierl FX; Dieterle C; Feldmeier H; Gutt B; Landgraf R
Article: DIABETOLOGIA. 1999;42(Suppl 1):a1-a330
35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999.
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Alla övriga publikationer

Preprint: BIORXIV. 2025
PET imaging of an antisense oligonucleotide in the living non-human primate brain using click chemistry
Cook BE; Pickel TC; Nag S; Bolduc PN; Beshr R; Morén AF; Muste C; Boscutti G; Jiang D; Yuan L; Datta P; Ochniewicz P; Meynaq YK; Tang S-P; Plisson C; Amatruda M; Zhang Q; DuBois JM; Delavari A; Klein SK; Polyak I; Shoroye A; Girmay S; Halldin C; Martarello L; Peterson EA; Kaliszczak M
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2024;51:S115
Labelling of a Bruton's Tyrosine Kinase (BTK) Inhibitor [¹¹C]BIO-2008846 in three different positions and evaluated through PET scans in NHP
Nag S; Moren A; Datta P; Meynaq YK; Kaliszczak M; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2024;51:S818-S819
Imaging Synaptic Vesicle Protein SV2C with 18F-UCB-F: An In Vitro Autoradiography and In Vivo NHP PET Study
Nag S; Moren AF; Sousa V; Datta P; Meynaq YK; Valade A; Vermeiren C; Motte P; Mercier J; Agren H; Halldin C; Varrone A
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2024;51:S820
Development of two pyrrolo-pyridine and -pyrimidine LRRK2 selective PET radioligands
Stepanov V; Nag S; Takano A; Arakawa R; Swedberg M; Amini N; Smith GP; Mikkelsen G; Jensen T; Hentzer M; Christensen KV; Bang-Andersen B; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2024;51:S816-S817
GMP validation (CMC) and Radiation dosimetry for clinical application of a novel α7-nAChR radioligand: [¹¹C]Kln83
Jia K; Nag S; Datta P; Moren A; Bolin M; Asem H; Agren H; Langstrom B; Halldin C; Nordberg A
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2023;50(SUPPL 1):S257
In vivo quantification of [¹¹C]BIO-1819578, a novel radioligand for O-GlcNAcase, in non-human primates using Positron Emission Tomography
Bolin M; Nag S; Datta P; Arakawa R; Meynaq YK; Lin E; Genung N; Hering H; Guckian K; Martarello L; Kaliszczak M; Farde L; Stenkrona P; Halldin C; Moren AF
Conference publication: NUCLEAR MEDICINE AND BIOLOGY. 2023;126:S111-S112
Discovery of [¹⁸F]F-687-TCO: An Optimized Tracer for Pretargeted PET Imaging in the CNS
Cook B; Pickel T; Jiang D; Bolduc P; Nag S; Tang S-P; Nasr K; Boscutti G; Plisson C; Moren A; Ochniewicz P; Halldin C; Peterson E; Martarello L; Kaliszczak M
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2022;49(SUPPL 1):S238
Development of a novel ¹¹CO labelled PET radioligand ¹¹C-BIO-1819578 for the detection of O-GlcNAcase (OGA) enzyme in the living brain
Nag S; Arakawa R; Datta P; Forsberg A; Moein M; Bolin M; Lin T; Genung N; Heiring H; Guckian K; Martarello L; Kaliszczak M; Halldin C
Review: EJNMMI RADIOPHARMACY AND CHEMISTRY. 2022;7(1):18
Practical considerations for navigating the regulatory landscape of non-clinical studies for clinical translation of radiopharmaceuticals
Korde A; Mikolajczak R; Kolenc P; Bouziotis P; Westin H; Lauritzen M; Koole M; Herth MM; Bardies M; Martins AF; Paulo A; Lyashchenko SK; Todde S; Nag S; Lamprou E; Abrunhosa A; Giammarile F; Decristoforo C
Conference publication: NUCLEAR MEDICINE AND BIOLOGY. 2022;108:S26
Synthesis and biological evaluation of a novel radioligand [¹¹C]BIO-1790735 for detection of O-GlcNAcase (OGA) enzyme activity
Nag S; Arakawa R; Datta P; Moren A; Varrone A; Moein MM; Bolin M; Lin E; Genung N; Martarello L; Kaliszczak M; Halldin C
Conference publication: NUCLEAR MEDICINE AND BIOLOGY. 2022;108:S122-S123
Automated radiolabeling of [⁶⁸Ga]Ga-DOTATOC using the iMiDEV™ automated microfluidic radiosynthesizer
Chandrashekara HK; Thuy T; Jussing E; Tanguy L; Langstrom B; Le Meunier L; Halldin C; Nag S
Preprint: RESEARCH SQUARE. 2021
Target Occupancy Study and Whole-Body Dosimetry with a MAGL PET Ligand 11C-PF-06809247 in non-human Primates
Arakawa R; Takano A; Nag S; Jia Z; Amini N; Maresca K; Zhang L; Keliher E; Butler C; Piro J; Samad T; Smith D; Nason D; O’Neil S; Trapa P; Fonseca K; Litchfield J; McCarthy T; Carson R; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2021;48(SUPPL 1):S223-S224
Radiosynthesis of [¹¹C]Flumazenil and [¹¹C]Deprenyl using a fully automated iMiDEV microfluidic radiosynthesizer
Chandrashekara HM; Tanguy L; Langstrom B; Le Meunier L; Halldin C; Nag S
Preprint: RESEARCH SQUARE. 2021
Target Occupancy Study and Whole-Body Dosimetry With a MAGL PET Ligand 11C-PF-06809247 in Non-Human Primates
Arakawa R; Takano A; Nag S; Jia Z; Amini N; Maresca KP; Zhang L; Keliher EJ; Butler CR; Piro JR; Samad TA; Smith D; Nason D; O’Neil S; Trapa P; Fonseca KR; Litchfield J; McCarthy T; Carson RE; Halldin C
Corrigendum: MOVEMENT DISORDERS. 2020;35(12):2363-2364
PET Molecular Imaging of Phosphodiesterase 10A: An Early Biomarker of Huntington's Disease Progression (vol 35, pg 606, 2020)
Fazio P; Fitzer-Attas CJ; Mrzljak L; Bronzova J; Nag S; Warner JH; Landwehrmeyer B; Al-Tawil N; Halldin C; Forsberg A; Ware J; Dilda V; Wood A; Sampaio C; Varrone A
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2020;47(SUPPL 1):S493-S494
A Positron Emission Tomography (PET) Study to Examine the Brain Binding of[¹¹C]-PXT012253 in Healthy Subjects
Stenkrona P; Arakawa R; Holst H; Nag S; Moein MM; Jia Z; Halldin C; Varrone A
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2019;46(SUPPL 1):S228
Development of novel ¹¹C- labeled ASEM analogs for detection of neuronal nicotinic acetylcholine receptors (α7-nAChR)
Nag S; Jia Z; Datta P; Azpiazu PM; Arakawa R; Varnas K; Lemoine L; Kuang G; Agren H; Langstram B; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2019;46(SUPPL 1):S852
Development of a M4 PAM PET radioligand - [¹¹C]PF-06885190-for a study in nonhuman primates
Nag S; Arakawa R; Maresca K; Butler C; Chen L; Jia Z; Lachapelle E; Jahan M; McCarthy T; Zhang L; Halldin C
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2019;39:84
PET imaging of [¹¹C]BIIB104, an AMPA positive modulator, in the living NHP brain
Kaliszczak M; Nag S; Dandapani S; Arakawa R; Forsberg A; Varnas K; Beaver J; Shaffer C; Halldin C; Martarello L
Conference publication: JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2019;62:S391
Evaluation of the brain bio-distribution of [¹¹C]BIIB104, an AMPA positive allosteric modulator in the living NHP brain using positron emission tomography
Nag S; Jia Z; Arakawa R; Varnas K; Mohammad M; Datta P; Scott D; Shaffer C; Hutchison M; Kaliszczak M; Martarello L; Halldin C
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S322-S323
Norepinephrine transporter occupancy of venlafaxine in patients with major depressive disorder using positron emission tomography and [18F]FMeNERD2
Arakawa R; Stenkrona P; Takano A; Svensson J; Andersson M; Nag S; Asami Y; Halldin C; Lundberg J
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2018;43:S133-S134
Quantification of Norepinephrine Transporter Occupancy of Venlafaxine Extended-Release in Patients With Major Depressive Disorder Using Positron Emission Tomography and Radioligand [18 F]FMeNER-D2
Arakawa R; Stenkrona P; Takano A; Svensson J; Andersson M; Nag S; Asamin Y; Hirano Y; Halldin C; Lundberg J
Preprint: BIORXIV. 2018
Proof of concept: Malaria rapid diagnostic tests and massively parallel sequencing for surveillance of molecular markers of antimalarial resistance in Bissau, Guinea-Bissau during 2014-2017
Nag S; Ursing J; Rodrigues A; Crespo M; Krogsgaard C; Lund O; Aarestrup F; Alifrangis M; Kofoed P-E
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45:S213
PET Imaging of Beta-secretase 1 in The Human Brain: Quantification and Test-Retest Examination with [¹⁸F]PF-06684511
Varrone A; Arakawa R; Takano A; Stenkrona P; Nag S; Stepanov V; Jahan M; Chen L; He P; Villalobos A; McCarthy T; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45:S643-S644
New candidate high-affinity full agonist PET radioligands for imaging 5-HT_1Breceptors have very low brain uptake and no signal
Lindberg A; Lu S; Liow J; Zoghbi S; Frankland MP; Gladding RL; Innis RB; Nag S; Schou M; Elmore CS; Halldin C; Pike VW
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45:S144
Recent advances in translational study of ¹⁸F-DABTA-11, a PET tracer for alpha-synuclein aggregates
Yousefi BH; Shi K; Nag S; Arakawa R; Herz M; Braeuer M; Reder S; Halldin C; Wester H; Schwaiger M; Weber W; Arzberger T; Yakushev I
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45:S660-S661
Evaluation of [¹¹C]PXT012253 and [¹⁸F]PXT012251 as PET radioligands for mGlu4 allosteric modulators in non-human primates
Nag S; Arakawa R; Takano A; Jia Z; Jahan M; Forsberg A; Duvey G; Halldin C; Charvin D
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45:S222-S223
Development of the first ¹⁸F-labeled PET radioligand for imaging 5-HT _1Breceptors: [¹⁸F]AZ10419096
Lindberg A; Nag S; Moein M; Schou M; Arakawa R; Elmore CS; Pike VW; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45:S143-S144
Synthesis and biological evaluation of a novel mGluR5 radioligand: [¹⁸F]AZD9272
Nag S; Varnas K; Arakawa R; Takano A; Jahan M; Schou M; Halldin C; Farde L
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45:S142-S143
Development of a novel reversible F-18 labelled SL25.1188 analog for the detection of MAO-B activity
Nag S; Dahl K; Bernard-Gauthier V; Varnas K; Narayanaswami V; Moein M; Arakawa R; Vasdev N; Halldin C
Conference publication: JOURNAL OF NUCLEAR MEDICINE. 2018;59
Synthesis of a novel ¹⁸F-labeled radioligand for monoamine oxidase-B and preliminary PET imaging in non-human primate
Dahl K; Bernard-Gauthier V; Nag S; Varnaosi K; Narayanaswami V; Moein M; Arakawa R; Vasdev N; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2017;44:S367-S368
Radiosynthesis, initial evaluation and whole-body dosimetry of a beta-secretase (BACE) PET radioligand [¹¹C] PF-06684511 in non-human
Arakawa R; Chen L; Takano A; Brodney MA; Dutra J; Stepanov V; Nag S; Doran S; McCarthy T; Nolan C; Villalobos A; Zhang L; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2017;44:S172
Human Whole-body Biodistribution and Radiation Dosimetry of [¹⁸F]PF-06684511, a Novel Radioligand for Brain Imaging of Beta-secretase
Varrone A; Arakawa R; Takano A; Nag S; Stepanov V; Stenkrona P; Gryback P; Bolin M; Chen L; Zhang L; He P; Villalobos A; McCarthy T; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2017;44:S364-S365
Injected Mass is a Limiting Factor for Small Animal PET Studies Using High-Affinity Radioligands: Evidence from a Study Using [11C]- and [18F]Fallypride
Toth M; Nag S; Jia Z; Haggkvist J; Mukherjee J; Varrone A; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2017;44:S366-S367
Identification and development of a highly specific monoacylglycerol lipase (MAGL) PET tracer ¹¹C-PF-06809247
Butler CR; Takano A; Nag S; Arakawa R; Maresca KP; Piro JR; Samad T; Smith D; Nason D; O'Neil S; McAllister L; Grimwood S; Trapa P; McCarthy T; Villalobos A; Halldin C; Zhang L
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2017;44:S265
Synthesis and biological evaluation of novel five F-18 labelled radioligands for detection of MAO-B activity
Nag S; Jackson A; Takano A; Jia K; Arakawa R; Jahan M; Ahmad R; Luthra S; Maior R; Halldin C
Conference publication: MOVEMENT DISORDERS. 2017;32
Imaging of phosphodiesterase 10 A (PDE10A) enzyme levels in the living human brain of Huntington's disease gene expansion carriers and healthy controls with positron emission tomography.
Fazio P; Fittzer-Attas C; Bronzova J; Nag S; Warner J; Landwehrmeyer B; Al-Tawil N; Halldin C; Mrzljak L; Sampaio C; Varrone A
Conference publication: JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2017;60:S77
Development of BACE-selective PET LIGANDS - [¹⁸F]/[¹¹C]PF-06684511
Nag S; Stepanov V; Takano A; Chen L; Brodney MA; Arakawa A; Doran J; Dutra C; Neill BO; Buzon L; Nolan CE; Mccarthy T; Mccarthy T; Villalobos A; Bales K; Zhang L; Halldin C
Conference publication: JOURNAL OF NUCLEAR MEDICINE. 2017;58
Radiosynthesis of [¹¹C] SL25.1188 via "in-Loop" [¹¹C] CO₂ Fixation: Pre-clinical Evaluation for MAO-B Activity in Alzheimer's Disease
Dahl K; Collier T; Cheng R; Svedberg M; Toth M; Das A; Nag S; Liang S; Halldin C; Vasdev N
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2016;43:S99-S100
Target occupancy of PF-06663195 measured with a beta-secretase (BACE) PET radioligand [¹⁸F] PF-06684511 in non-human primates
Arakawa R; Chen L; Takano A; Brodney MA; Nag S; Chang C; Amini N; Doran S; McCarthy T; Nolan C; Zhang L; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2016;43:S94-S95
Radio-labeling and initial evaluation of a novel beta-secretase (BACE)-selective PET radioligand, [¹⁸F] PF-06684511, in nonhuman primates
Takano A; Chen L; Nag S; Brodney MA; Amini N; Chang C; Arakawa R; Doran S; Dutra J; McCarthy T; Nolan C; O'Neil B; Villalobos A; Zhang L; Halldin C
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2016;36:614-615
MAPPING MAO-B WITH FLUORINE-18 LABELED DEUTERATED FLUORODEPRENYL (18F-FLUORODEPRENYL-D2). DEVELOPMENT, IN VITRO AUTORADIOGRAPHY AND IN VIVO EVALUATION IN NON-HUMAN PRIMATES.
Nag S; Fazio P; Svedberg M; Amini N; Lehmann L; Kettschau G; Heinrich T; Leesch S; Catafau A; Varrone A; Halldin C
Conference publication: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2015;93(4):458
NEXT-GENERATION SEQUENCING PLATFORM BASED ON MALARIA RAPID DIAGNOSTIC TESTS FOR SURVEILLANCE OF ANTIMALARIAL DRUG RESISTANCE
Nag S; Dalgaard M; Ndiaye M; Kofoed P-EL; Rodrigues A; Ursing J; Kavishe R; Alifrangis M; Lund O; Aarestrup FM
Conference publication: JOURNAL OF NUCLEAR MEDICINE. 2014;55
The automated receptor imaging system (ARIS) for quantitative image processing to estimate binding parameters for dopamine transporter [18F]FE-PE2I studies in non-human primate (NHP)
Odano I; Guenther I; Wang Z; Serrano R; Gsell W; Chang YQ; Nag S; Chimon G; Varrone A; Halldin C
Conference publication: JOURNAL OF NUCLEAR MEDICINE. 2014;55
The automated receptor imaging system (ARIS) for quantitative image processing to estimate binding parameters for dopamine transporter [18F]FE-PE2I studies in non-human primate (NHP)
Odano I; Guenther I; Wang Z; Serrano R; Gsell W; Chang YQ; Nag S; Chimon G; Varrone A; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2013;40:S199
Development of Novel F-18 Labeled Deuterated Analogues of Fluorodeprenyl and Fluororasagiline by PET to Study MAO-B Activity
Nag S; Lehmann L; Kettschau G; Heinrich T; Thiele A; Toth M; Halldin C
Doctoral thesis: 2013
Development of novel fluorine-18 labeled PET radioligands for monoamine oxidase B (MAO-B)
Nag S
Conference publication: JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2013;56:S310
Synthesis and evaluation of novel F-18 labeled deuterated fluororasagilineby PET to study MAO-B activity
Nag S; Lehmann L; Kettschau G; Thiele A; Varrone A; Toth M; Gulyas B; Dinkelborg L; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2012;39:S267
Synthesis and Biological Evaluation of Novel F-18 Labeled Radioligands for Detection of MAO-B Activity
Nag S; Lehmann L; Kettschau G; Thiele A; Heinrich T; Varrone A; Gulyas B; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2012;39:S182
Initial Evaluation of the Novel Dopamine Transporter Radioligand [18F]FE-PE2I in Healthy Controls and Parkinson's Disease Patients
Varrone A; Forsberg A; Nakao R; Amini N; Nag S; Svenningsson P; Halldin C; Farde L
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2012;32:S101-S102
Synthesis and PET evaluation of a novel F-18 labeled deuterated fluorodeprenyl ([¹⁸F]fluorodeprenyl-D2) radioligand to study MAO-B activity
Nag S; Lehmann L; Kettschau G; Heinrich T; Thiele A; Varrone A; Gulyas B; Halldin C
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2012;32:S70-S71
Preliminary evaluation of the quantification and metabolism in human subjects of the dopamine transporter redioligand [¹⁸F]FE-PE21
Vantone A; Nakao R; Amini N; Forberg A; Nag S; Farde L; Halldin C
Book chapter: RADIOCHEMICAL SYNTHESES. 2012;p. 265-273
Synthesis of [carbonyl‐11C]Way‐100635
Andersson JD; Nag S; Krasikova RN; Pike VW; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2011;38:S148
PET investigation of in vivo SERT and NET occupancy by venlafaxine and milnacipran in non-human primates
Takano A; Nag S; Halldin C; Farde L
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2011;38:S123
In Vivo Imaging of the 18-kDa Translocator Protein (TSPO) with [18F]FEDAA1106 and PET Does Not Show Increased Binding In Alzheimer's Disease Patients
Varrone A; Mattsson P; Forsberg A; Takano A; Nag S; Boellaard R; Al Tawil N; Joenhagen ME; Hoffmann A; Zimmermann T; Schultze-Mosgau M; Thiele A; Lammertsma AA; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2011;38:S107
In vivo TSPO imaging in patients with Multiple Sclerosis: A PET study with [18F]FEDAA1106
Takano A; Piehl F; Hillert J; Varrone A; Nag S; Villemagne V; Rowe CC; Macdonell R; Al Tawil N; Kucunski T; Hoffmann A; Zimmermann T; Schultze-Mosgau M; Thiele A; Halldin C
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2011;21:S320-S321
In vivo monoamine transporter occupancy by venlafaxine and milnacipran in non-human primates
Takano A; Nag S; Halldin C; Farde L
Conference publication: JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2011;54:S269
Synthesis and evaluation of [¹⁸F]fluororasagiline, a novel PET radioligand for MAO-B
Nag S; Lehmann L; Kettschau G; Thiele A; Varrone A; Gulyas B; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2010;37:S205
A Fluorine-18 Labeled Deprenyl PET Radioligand For in vivo Evaluation of MAO-B
Nag S; Lehmann L; Kettschau G; Heinrich T; Brumby T; Thiele A; Varrone A; Gulyas B; Halldin C
Meeting abstract: NEUROIMAGE. 2010;52:S121
Synthesis of three F-18 labeled analogues of 1-deprenyl for PET Studies of monoamine oxidase B
Nag S; Lehmann L; Kettschau G; Heinrich T; Brumby T; Thiele A; Varrone A; Gulyas B; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2006;33:S211
[¹¹C] Cyclopropyl-FLB 457:: PET examination of a more D2 selective high affinity radioligand for extrastriatal D2 dopamine receptors
Airaksinen AJ; Finnema S; Nag S; Mukherjee J; Farde L; Halldin C
Meeting abstract: NEUROIMAGE. 2006;31:T15
A new PET radioligand [11C]cyclopropyl-FLB 457 for imaging extrastriatal dopamine D2 receptors:: Evaluation in monkey and comparison to [11C]FLB 457 and [11C]Fallypride
Airaksinen AJ; Finnema SJ; Nag S; Mukherjee J; Gulyas B; Halldin C
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Forskningsbidrag

Development of PET tracer for imaging SV2C in Parkinson´s disease
Michael J. Fox Foundation for Parkinson's Research
1 January 2023 - 31 December 2025
Development of an imaging marker for synaptic vesicular glycoprotein SV2C: a specific target for synaptic density in Parkinson´s disease
Swedish Research Council
1 January 2021 - 31 December 2023

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Senior Forskningsspecialist, Klinisk neurovetenskap, Karolinska Institutet, 2024-
Forskningsspecialist, Klinisk neurovetenskap, Karolinska Institutet, 2022-2024

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Medicine Doktorsexamen, Institutionen för klinisk neurovetenskap, Karolinska Institutet, 2013

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