Pia Dosenovic

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: CELL REPORTS MEDICINE. 2024;5(6):101577
Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies
Sheward DJ; Pushparaj P; Das H; Greaney AJ; Kim C; Kim S; Hanke L; Hyllner E; Dyrdak R; Lee J; Dopico XC; Dosenovic P; Peacock TP; McInerney GM; Albert J; Corcoran M; Bloom JD; Murrell B; Hedestam GBK; Hallberg BM
Article: JOURNAL OF VIROLOGY. 2020;94(6):e01883-e01819
Neutralizing Antibody Induction by HIV-1 Envelope Glycoprotein SOSIP Trimers on Iron Oxide Nanoparticles May Be Impaired by Mannose Binding Lectin.
Ringe RP; Cruz Portillo VM; Dosenovic P; Ketas TJ; Ozorowski G; Nogal B; Perez L; LaBranche CC; Lim J; Francomano E; Wilson IA; Sanders RW; Ward AB; Montefiori DC; Nussenzweig MC; Klasse PJ; Cupo A; Moore JP
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2019;216(10):2316-2330
Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses.
Dosenovic P; Pettersson A-K; Wall A; Thientosapol ES; Feng J; Weidle C; Bhullar K; Kara EE; Hartweger H; Pai JA; Gray MD; Parks KR; Taylor JJ; Pancera M; Stamatatos L; Nussenzweig MC; McGuire AT
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2019;216(6):1301-1310
HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells.
Hartweger H; McGuire AT; Horning M; Taylor JJ; Dosenovic P; Yost D; Gazumyan A; Seaman MS; Stamatatos L; Jankovic M; Nussenzweig MC
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(18):4743-4748
Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen-binding affinity.
Dosenovic P; Kara EE; Pettersson A-K; McGuire AT; Gray M; Hartweger H; Thientosapol ES; Stamatatos L; Nussenzweig MC
Article: JOURNAL OF IMMUNOLOGY. 2018;200(2):775-787
Altered Marginal Zone B Cell Selection in the Absence of IκBNS
Adori M; Pedersen GK; Adori C; Erikson E; Khoenkhoen S; Stark JM; Choi JH; Dosenovic P; Karlsson MCI; Beutler B; Hedestam GBK
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2017;214(9):2573-2590
Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.
Medina-Ramírez M; Garces F; Escolano A; Skog P; de Taeye SW; Del Moral-Sanchez I; McGuire AT; Yasmeen A; Behrens A-J; Ozorowski G; van den Kerkhof TLGM; Freund NT; Dosenovic P; Hua Y; Gitlin AD; Cupo A; van der Woude P; Golabek M; Sliepen K; Blane T; Kootstra N; van Breemen MJ; Pritchard LK; Stanfield RL; Crispin M; Ward AB; Stamatatos L; Klasse PJ; Moore JP; Nemazee D; Nussenzweig MC; Wilson IA; Sanders RW
Article: IMMUNITY. 2016;45(3):483-496
HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.
Steichen JM; Kulp DW; Tokatlian T; Escolano A; Dosenovic P; Stanfield RL; McCoy LE; Ozorowski G; Hu X; Kalyuzhniy O; Briney B; Schiffner T; Garces F; Freund NT; Gitlin AD; Menis S; Georgeson E; Kubitz M; Adachi Y; Jones M; Mutafyan AA; Yun DS; Mayer CT; Ward AB; Burton DR; Wilson IA; Irvine DJ; Nussenzweig MC; Schief WR
Article: CELL. 2016;166(6):1445-1458.e12
Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice.
Escolano A; Steichen JM; Dosenovic P; Kulp DW; Golijanin J; Sok D; Freund NT; Gitlin AD; Oliveira T; Araki T; Lowe S; Chen ST; Heinemann J; Yao K-H; Georgeson E; Saye-Francisco KL; Gazumyan A; Adachi Y; Kubitz M; Burton DR; Schief WR; Nussenzweig MC
Article: NATURE COMMUNICATIONS. 2016;7:10618
Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice.
McGuire AT; Gray MD; Dosenovic P; Gitlin AD; Freund NT; Petersen J; Correnti C; Johnsen W; Kegel R; Stuart AB; Glenn J; Seaman MS; Schief WR; Strong RK; Nussenzweig MC; Stamatatos L
Article: CELL. 2015;161(7):1505-1515
Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice.
Dosenovic P; von Boehmer L; Escolano A; Jardine J; Freund NT; Gitlin AD; McGuire AT; Kulp DW; Oliveira T; Scharf L; Pietzsch J; Gray MD; Cupo A; van Gils MJ; Yao K-H; Liu C; Gazumyan A; Seaman MS; Björkman PJ; Sanders RW; Moore JP; Stamatatos L; Schief WR; Nussenzweig MC
Article: IMMUNOLOGY AND CELL BIOLOGY. 2015;93(2):136-146
Slc15a4 function is required for intact class switch recombination to IgG2c in response to TLR9 stimulation
Dosenovic P; Adori M; Adams WC; Pedersen GK; Soldemo M; Beutler B; Hedestam GBK
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(39):E4119-E4126
B-1a transitional cells are phenotypically distinct and are lacking in mice deficient in IκBNS
Pedersen GK; Adori M; Khoenkhoen S; Dosenovic P; Beutler B; Hedestam GBK
Article: JOURNAL OF IMMUNOLOGY. 2013;191(1):44-51
Independent Expansion of Epitope-Specific Plasma Cell Responses upon HIV-1 Envelope Glycoprotein Immunization
Forsell MNE; Soldemo M; Dosenovic P; Wyatt RT; Karlsson MCI; Hedestam GBK
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(31):12286-12293
A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity
Arnold CN; Pirie E; Dosenovic P; McInerney GM; Xia Y; Wang N; Li X; Siggs OM; Hedestam GBK; Beutler B
Article: JOURNAL OF IMMUNOLOGY. 2012;188(12):6018-6026
BLyS-Mediated Modulation of Naive B Cell Subsets Impacts HIV Env-Induced Antibody Responses
Dosenovic P; Soldemo M; Scholz JL; O'Dell S; Grasset EK; Pelletier N; Karlsson MCI; Mascola JR; Wyatt RT; Cancro MP; Hedestam GBK
Article: PLOS ONE. 2011;6(1):e16074
Heterologous Epitope-Scaffold Prime:Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant
Guenaga J; Dosenovic P; Ofek G; Baker D; Schief WR; Kwong PD; Hedestam GBK; Wyatt RT
Article: JOURNAL OF VIROLOGY. 2010;84(4):1683-1695
Influence of Novel CD4 Binding-Defective HIV-1 Envelope Glycoprotein Immunogens on Neutralizing Antibody and T-Cell Responses in Nonhuman Primates
Douagi I; Forsell MNE; Sundling C; O'Dell S; Feng Y; Dosenovic P; Li Y; Seder R; Lore K; Mascola JR; Wyatt RT; Hedestam GBK
Article: JOURNAL OF IMMUNOLOGY. 2009;183(5):3373-3382
Selective Expansion of HIV-1 Envelope Glycoprotein-Specific B Cell Subsets Recognizing Distinct Structural Elements Following Immunization
Dosenovic P; Chakrabarti B; Soldemo M; Douagi I; Forsell MNE; Li Y; Phogat A; Paulie S; Hoxie J; Wyatt RT; Hedestam GBK
Article: JOURNAL OF VIROLOGY. 2009;83(2):540-551
Human Immunodeficiency Virus Type 1 Env Trimer Immunization of Macaques and Impact of Priming with Viral Vector or Stabilized Core Protein
Moerner A; Douagi I; Forsell MNE; Sundling C; Dosenovic P; O'Dell S; Dey B; Kwong PD; Voss G; Thorstensson R; Mascola JR; Wyatt RT; Hedestam GBK
Article: JOURNAL OF GENERAL VIROLOGY. 2007;88(Pt 10):2774-2779
Increased human immunodeficiency virus type 1 Env expression and antibody induction using an enhanced alphavirus vector
Forsell MNE; McInerney GM; Dosenovic P; Hidmark AS; Eriksson C; Liljestorm P; Grundner C; Hedestam GBK
Article: JOURNAL OF VIROLOGY. 2007;81(16):8677-8684
Semliki forest virus nonstructural protein 2 is involved in suppression of the type I interferon response
Breakwell L; Dosenovic P; Hedestam GBK; D'Amato M; Liljestrom P; Fazakerley J; McInerney GM
Article: JOURNAL OF VIROLOGY. 2006;80(14):7100-7110
Humoral responses against coimmunized protein antigen but not against alphavirus-encoded antigens require alpha/beta interferon signaling
Hidmark AS; Nordstrom EKL; Dosenovic P; Forsell MNE; Liljestrom P; Hedestam GBK
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Alla övriga publikationer

Review: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2017;214(1):3-16
Progress toward active or passive HIV-1 vaccination.
Escolano A; Dosenovic P; Nussenzweig MC
Review: SCIENCE. 2013;341(6151):1199-1204
Antibodies in HIV-1 vaccine development and therapy.
Klein F; Mouquet H; Dosenovic P; Scheid JF; Scharf L; Nussenzweig MC

Anställningar

Senior Forskare, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2023-

Examina och utbildning

Medicine Doktorsexamen, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2012

Artiklar

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Anställningar

Examina och utbildning

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