Patricia Muñoz

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: STEM CELL RESEARCH. 2025;82:103628
Generation of a genetically encoded voltage indicator MARINA reporter human iPS cell line using Cas9 (VULSCi002-A-2)
Petruskeviciute A; Simuliunaite U; Polanco CM; Rojas B; Kuras S; Valatkaite-Rakstiene B; Norvilas R; Vijaya AK; Munoz P; Neniskyte U; Jakubauskas A; Burokas A; Nalvarte I; Inzunza J; Naumovas D; Stoskus M; Griskevicius L; Baltriukiene D; Arias J
Journal article: STEM CELL RESEARCH. 2025;82:103628
Generation of a genetically encoded voltage indicator MARINA reporter human iPS cell line using Cas9 (VULSCi002-A-2).
Petruškevičiūtė A; Šimuliūnaitė U; Polanco CM; Rojas B; Kuras S; Valatkaitė-Rakštienė B; Norvilas R; Vijaya AK; Muñoz P; Neniškytė U; Jakubauskas A; Burokas A; Nalvarte I; Inzunza J; Naumovas D; Stoškus M; Griškevičius L; Baltriukienė D; Arias J
Article: CELLS. 2024;13(21):1811
Proof-of-Concept for Long-Term Human Endometrial Epithelial Organoids in Modeling Menstrual Cycle Responses
Jiang Y; Palomares AR; Munoz P; Nalvarte I; Acharya G; Inzunza J; Varshney M; Rodriguez-Wallberg KA
Article: NEUROTOXICITY RESEARCH. 2022;40(6):2135-2147
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species
Santos CC; Cardim-Pires TR; Shvachiy L; Fonseca-Fonseca LA; Munoz P; Almeida AMAN; Costa ACS; Teles-Souza J; Ochoa-Rodriguez E; Dias Costa MDF; Palhano FL; Segura-Aguilar J; Barbosa DB; do Bomfim MR; dos Santos Junior MC; Leite FHA; da Rocha Pita SS; Costa SL; Nunez-Figueredo Y; Outeiro TF; Foguel D; Amaral Silva VD
Article: NEUROTOXICITY RESEARCH. 2021;39(2):182-190
Cellular Trafficking of Glutathione Transferase M2-2 Between U373MG and SHSY-S7 Cells is Mediated by Exosomes
Valdes R; Armijo A; Munoz P; Hultenby K; Hagg A; Inzunza J; Nalvarte I; Varshney M; Mannervik B; Segura-Aguilar J
Article: NEUROTOXICITY RESEARCH. 2020;38(3):579-584
The Flavonoid Agathisflavone from Poincianella pyramidalis Prevents Aminochrome Neurotoxicity
Santos CC; Munoz P; Almeida AMAN; de Lima David JP; David JM; Costa SL; Segura-Aguilar J; Amaral Silva VD
Article: CLIN PHARMACOL TRANSL MED. 2019;3(1):125-133
Protective Effects of Crude Plant Extracts against Aminochrome-induced toxicity in Human Astrocytoma Cells: Implications for Parkinson's Disease.
Ngoungoure VLN; Muñoz P; Tizabi Y; Valdes R; Moundipa PF; Segura-Aguilar J
Article: NEUROTOXICITY RESEARCH. 2019;35(1):255-259
DT-Diaphorase Prevents Aminochrome-Induced Lysosome Dysfunction in SH-SY5Y Cells
Melendez C; Munoz P; Segura-Aguilar J
Article: ACS CHEMICAL NEUROSCIENCE. 2017;8(10):2247-2253
The Importance of Mitophagy in Maintaining Mitochondrial Function in U373MG Cells. Bafilomycin A1 Restores Aminochrome-lnduced Mitochondrial Damage
Huenchuguala S; Munoz P; Segura-Aguilar J
Article: NEUROTOXICITY RESEARCH. 2017;32(3):362-367
DT-diaphorase Protects Against Autophagy Induced by Aminochrome-Dependent Alpha-Synuclein Oligomers
Munoz PS; Segura-Aguilar J
Article: NEUROTOXICITY RESEARCH. 2017;32(2):172-174
On the Role of Mining Exposure in Epigenetic Effects in Parkinson's Disease
Castillo S; Munoz P; Isabel Behrens M; Diaz-Grez F; Segura-Aguilar J
Article: NEUROTOXICITY RESEARCH. 2017;32(1):134-140
On the Role of DT-Diaphorase Inhibition in Aminochrome-Induced Neurotoxicity In Vivo
Herrera-Soto A; Diaz-Veliz G; Mora S; Munoz P; Henny P; Steinbusch HWM; Segura-Aguilar J
Article: ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS. 2017;89(1):247-261
Autophagy protects against neural cell death induced by piperidine alkaloids present in Prosopis juliflora (Mesquite)
Silva VDA; Cuevas C; Munoz P; Villa M; Ahumada-Castro U; Huenchuguala S; Dos Santos CC; De Araujo FM; Ferreira RS; Da Silva VB; Silva JHCE; Soares EN; Velozo ES; Segura-Aguilar J; Costa SL
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2016;73(18):3583-3597
Aminochrome induces dopaminergic neuronal dysfunction: a new animal model for Parkinson's disease
Herrera A; Munoz P; Paris I; Diaz-Veliz G; Mora S; Inzunza J; Hultenby K; Cardenas C; Jana F; Raisman-Vozari R; Gysling K; Abarca J; Steinbusch HWM; Segura-Aguilar J
Journal article: NEUROTOXICOLOGY. 2016;55:10-12
DT-diaphorase protects astrocytes from aminochrome-induced toxicity
Huenchuguala S; Munoz P; Graumann R; Paris I; Segura-Aguilar J
Article: NEUROTOXICITY RESEARCH. 2016;30(1):41-52
Impact of Plant-Derived Flavonoids on Neurodegenerative Diseases
Costa SL; Amaral Silva VD; Souza CDS; Santos CC; Paris I; Munoz P; Segura-Aguilar J
Article: NEUROTOXICITY RESEARCH. 2016;29(3):381-393
Aminochrome Toxicity is Mediated by Inhibition of Microtubules Polymerization Through the Formation of Adducts with Tubulin
Briceno A; Munoz P; Brito P; Huenchuguala S; Segura-Aguilar J; Paris IB
Article: CURRENT MEDICINAL CHEMISTRY. 2016;23(4):346-359
Aminochrome as New Preclinical Model to Find New Pharmacological Treatment that Stop the Development of Parkinson's Disease
Segura-Aguilar J; Munoz P; Paris I
Journal article: FRONTIERS IN NEUROSCIENCE. 2016;10:320
Commentary: Evaluation of Models of Parkinson's Disease (vol 10, 161, 2016)
Munoz P; Paris I; Segura-Aguilar J
Article: TOXICOLOGICAL SCIENCES. 2015;145(1):37-47
DT-Diaphorase Prevents Aminochrome-Induced Alpha-Synuclein Oligomer Formation and Neurotoxicity
Munoz P; Cardenas S; Huenchuguala S; Briceno A; Couve E; Paris I; Segura-Aguilar J
Article: NEUROTOXICITY RESEARCH. 2015;27(3):217-228
Glutathione Transferase-M2-2 Secreted from Glioblastoma Cell Protects SH-SY5Y Cells from Aminochrome Neurotoxicity
Cuevas C; Huenchuguala S; Munoz P; Villa M; Paris I; Mannervik B; Segura-Aguilar J
Article: AUTOPHAGY. 2014;10(4):618-630
Glutathione transferase mu 2 protects glioblastoma cells against aminochrome toxicity by preventing autophagy and lysosome dysfunction
Huenchuguala S; Munoz P; Zavala P; Villa M; Cuevas C; Ahumada U; Graumann R; Nore BF; Couve E; Mannervik B; Paris I; Segura-Aguilar J
Article: NEUROTOXICITY RESEARCH. 2013;24(1):94-101
One-Electron Reduction of 6-Hydroxydopamine Quinone is Essential in 6-Hydroxydopamine Neurotoxicity
Villa M; Munoz P; Ahumada-Castro U; Paris I; Jimenez A; Martinez I; Sevilla F; Segura-Aguilar J
Journal article: NEUROTOXICITY RESEARCH. 2012;22(3):249
Protective Effects of Nicotine Against Aminochrome-Induced Toxicity in Substantia Nigra Derived Cells: Implications for Parkinson's Disease (vol 22, pg 177, 2012)
Munoz P; Huenchuguala S; Paris I; Cuevas C; Villa M; Caviedes P; Segura-Aguilar J; Tizabi Y
Article: NEUROTOXICITY RESEARCH. 2012;22(2):177-180
Protective Effects of Nicotine Against Aminochrome-Induced Toxicity in Substantia Nigra Derived Cells: Implications for Parkinson's Disease
Munoz P; Huenchuguala S; Paris I; Cuevas C; Villa M; Caviedes P; Segura-Aguilar J; Tizabi Y
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2012;1822(7):1125-1136
Overexpression of VMAT-2 and DT-diaphorase protects substantia nigra-derived cells against aminochrome neurotoxicity
Munoz P; Paris I; Sanders LH; Greenamyre JT; Segura-Aguilar J
Article: TOXICOLOGICAL SCIENCES. 2011;121(2):376-388
Autophagy Protects Against Aminochrome-Induced Cell Death in Substantia Nigra-Derived Cell Line
Paris I; Munoz P; Huenchuguala S; Couve E; Sanders LH; Greenamyre JT; Caviedes P; Segura-Aguilar J
Article: CHEMICAL RESEARCH IN TOXICOLOGY. 2010;23(9):1492-1496
Stable Expression of Short Interfering RNA for DT-Diaphorase Induces Neurotoxicity
Lozano J; Munoz P; Nore BF; LeDoux S; Segura-Aguilar J
Article: NEUROTOXICITY RESEARCH. 2010;18(1):82-92
Aminochrome Induces Disruption of Actin, Alpha-, and Beta-Tubulin Cytoskeleton Networks in Substantia-Nigra-Derived Cell Line
Paris I; Perez-Pastene C; Cardenas S; Iturra P; Munoz P; Couve E; Caviedes P; Segura-Aguilar J
Article: NEUROTOXICITY RESEARCH. 2009;16(3):271-279
Molecular and Neurochemical Mechanisms in PD Pathogenesis
Paris I; Lozano J; Perez-Pastene C; Munoz P; Segura-Aguilar J
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Alla övriga publikationer

Review: NEURAL REGENERATION RESEARCH. 2022;17(9):1861-1866
Astrocytes protect dopaminergic neurons against aminochrome neurotoxicity
Segura-Aguilar J; Mannervik B; Inzunza J; Varshney M; Nalvarte I; Munoz P
Review: ANTIOXIDANTS. 2022;11(2):296
Neuroprotection against Aminochrome Neurotoxicity: Glutathione Transferase M2-2 and DT-Diaphorase
Segura-Aguilar J; Munoz P; Inzunza J; Varshney M; Nalvarte I; Mannervik B
Review: PROGRESS IN NEUROBIOLOGY. 2017;155:96-119
Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease
Zucca FA; Segura-Aguilar J; Ferrari E; Munoz P; Paris I; Sulzer D; Sarna T; Casella L; Zecca L
Review: ACS CHEMICAL NEUROSCIENCE. 2017;8(4):702-711
Are Dopamine Oxidation Metabolites Involved in the Loss of Dopaminergic Neurons in the Nigrostriatal System in Parkinson's Disease?
Herrera A; Munoz P; Steinbusch HWM; Segura-Aguilar J
Editorial comment: FRONTIERS IN PHARMACOLOGY. 2016;7:179
Commentary: A Humanized Clinically Calibrated Quantitative Systems Pharmacology Model for Hypokinetic Motor Symptomsin Parkinson's Disease
Munoz P; Segura-Aguilar J
Review: JOURNAL OF NEUROCHEMISTRY. 2014;129(6):898-915
Protective and toxic roles of dopamine in Parkinson's disease
Segura-Aguilar J; Paris I; Munoz P; Ferrari E; Zecca L; Zucca FA
Review: PARKINSONS DISEASE. 2012;2012:1-13
Dopamine Oxidation and Autophagy
Munoz P; Huenchuguala S; Paris I; Segura-Aguilar J

Anställningar

Forskningsassistent, Neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2025-2025
Anknuten till Forskning, Laboratoriemedicin, Karolinska Institutet, 2024-2025
Forskningsassistent, Neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2024-2024

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