Milena Zeitelhofer

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Docent i neurovetenskap
Specialistläkare i neurologi och psykiatri
Ledare för forskarteamet med följande medlemmar:
- Pär Pettersson, leg. psykolog
- Dennis Dam, leg. psykolog
- Georgios Gavriilidis, MD, PhD (post doc)

Forskningsbeskrivning

Klinisk utvärdering och epidemiologisk kartläggning av psykisk hälsa vid autoimmuna neurologiska sjukdomar, med särskilt fokus på multipel skleros.
Patologiska mekanismer vid autoimmun neuroinflammation med fokus på multipel skleros och perifera neuropatier.

Artiklar

Journal article: FRONTIERS IN GLOBAL WOMEN'S HEALTH. 2025;6:1580691
Profiling abuse and neglect of women with disabilities: a step towards prevention of mistreatment of vulnerable populations
Savard J; Gavriilidis G; Lindblad A; Huang J; Adzemovic MZ
Article: JOURNAL OF CLINICAL INVESTIGATION. 2025;135(5):e171077
PDGFRα inhibition reduces myofibroblast expansion in the fibrotic rim and enhances recovery after ischemic stroke
Protzmann J; Zeitelhofer M; Stefanitsch C; Torrente D; Adzemovic MZ; Matjunins K; Randel SJI; Lewandowski SA; Muhl L; Eriksson U; Nilsson I; Su EJ; Lawrence DA; Fredriksson L
Article: NATURE COMMUNICATIONS. 2024;15(1):383
The aging mouse CNS is protected by an autophagy-dependent microglia population promoted by IL-34
Berglund R; Cheng Y; Piket E; Adzemovic MZ; Zeitelhofer M; Olsson T; Guerreiro-Cacais AO; Jagodic M
Article: SCIENCE ADVANCES. 2022;8(17):eabn1823
Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis
Bronge M; Hogelin KA; Thomas OG; Ruhrmann S; Carvalho-Queiroz C; Nilsson OB; Kaiser A; Zeitelhofer M; Holmgren E; Linnerbauer M; Adzemovic MZ; Hellstrom C; Jelcic I; Liu H; Nilsson P; Hillert J; Brundin L; Fink K; Kockum I; Tengvall K; Martin R; Tegel H; Graslund T; Al Nimer F; Guerreiro-Cacais AO; Khademi M; Gafvelin G; Olsson T; Gronlund H
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2021;(175)
Rat Model of Widespread Cerebral Cortical Demyelination Induced by an Intracerebral Injection of Pro-Inflammatory Cytokines
Ucal M; Haindl MT; Adzemovic MZ; Zeitelhofer M; Schaefer U; Fazekas F; Hochmeister S
Article: JOURNAL OF NEUROINFLAMMATION. 2021;18(1):138
Anti-CD20 treatment effectively attenuates cortical pathology in a rat model of widespread cortical demyelination.
Haindl MT; Üçal M; Klaus B; Tögl L; Dohrmann J; Adzemovic MZ; Enzinger C; Hochmeister S
Article: SCIENTIFIC REPORTS. 2020;10(1):22383
Blocking PDGF-CC signaling ameliorates multiple sclerosis-like neuroinflammation by inhibiting disruption of the blood-brain barrier
Zeitelhofer M; Adzemovic MZ; Moessinger C; Stefanitsch C; Strell C; Muhl L; Brundin L; Fredriksson L; Olsson T; Eriksson U; Nilsson I
Article: FRONTIERS IN NEUROLOGY. 2020;11:600401
Effect of Vitamin D on Experimental Autoimmune Neuroinflammation Is Dependent on Haplotypes Comprising Naturally Occurring Allelic Variants of CIITA (Mhc2ta)
Hochmeister S; Aeinehband S; Dorris C; Berglund R; Haindl MT; Velikic V; Gustafsson SA; Olsson T; Piehl F; Jagodic M; Zeitelhofer M; Adzemovic MZ
Article: SCIENCE IMMUNOLOGY. 2020;5(52):eabb5077
Microglial autophagy-associated phagocytosis is essential for recovery from neuroinflammation.
Berglund R; Guerreiro-Cacais AO; Adzemovic MZ; Zeitelhofer M; Lund H; Ewing E; Ruhrmann S; Nutma E; Parsa R; Thessen-Hedreul M; Amor S; Harris RA; Olsson T; Jagodic M
Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(2):838-852
C-type lectin receptors Mcl and Mincle contro development of multiple sclerosis like neuroinflammation
N'diaye M; Brauner S; Flytzani S; Kular L; Warnecke A; Adzemovic MZ; Piket E; Min J-H; Edwards W; Mela F; Choi HY; Magg V; James T; Linden M; Reichardt HM; Daws MR; van Horssen J; Kockum I; Harris RA; Olsson T; Guerreiro-Cacais AO; Jagodic M
Article: CLINICAL EPIGENETICS. 2019;11(1):86
Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis
Kular L; Needhamsen M; Adzemovic MZ; Kramarova T; Gomez-Cabrero D; Ewing E; Piket E; Tegner J; Beck S; Piehl F; Brundin L; Jagodic M
Article: GLIA. 2019;67(3):467-481
The formation of a glial scar does not prohibit remyelination in an animal model of multiple sclerosis
Haindl MT; Koeck U; Zeitelhofer-Adzemovic M; Fazekas F; Hochmeister S
Article: PLOS ONE. 2018;13(7):e0200649
Preclinical toxicological assessment of a novel monoclonal antibody targeting human platelet-derived growth factor CC (PDGF-CC) in PDGF-CC^hum mice
Zeitelhofer M; Li H; Adzemovic MZ; Nilsson I; Muhl L; Scott AM; Eriksson U
Article: EXPERIMENTAL NEUROLOGY. 2017;294:32-44
Widespread cortical demyelination of both hemispheres can be induced by injection of pro-inflammatory cytokines via an implanted catheter in the cortex of MOG-immunized rats
Uecal M; Haindl MT; Adzemovic MZ; Strasser J; Theisl L; Zeitelhofer M; Kraitsy K; Ropele S; Schaefer U; Fazekas F; Hochmeister S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(9):E1678-E1687
Functional genomics analysis of vitamin D effects on CD4+T cells in vivo in experimental autoimmune encephalomyelitis
Zeitelhofer M; Adzemovic MZ; Gomez-Cabrero D; Bergman P; Hochmeister S; N'diaye M; Paulson A; Ruhrmann S; Almgren M; Tegner JN; Ekstrom TJ; Guerreiro-Cacais AO; Jagodic M
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2016;(117)
Immunohistochemical Analysis in the Rat Central Nervous System and Peripheral Lymph Node Tissue Sections
Adzemovic MZ; Zeitelhofer M; Leisser M; Koeck U; Kury A; Olsson T
Article: CELL AND TISSUE RESEARCH. 2016;365(1):51-63
Expression of vascular endothelial growth factor (VEGF)-B and its receptor (VEGFR1) in murine heart, lung and kidney
Muhl L; Moessinger C; Adzemovic MZ; Dijkstra MH; Nilsson I; Zeitelhofer M; Hagberg CE; Huusko J; Falkevall A; Yla-Herttuala S; Eriksson U
Article: PLOS ONE. 2016;11(5):e0154797
Lipocalin-2 as an Infection-Related Biomarker to Predict Clinical Outcome in Ischemic Stroke
Hochmeister S; Engel O; Adzemovic MZ; Pekar T; Kendlbacher P; Zeitelhofer M; Haindl M; Meisel A; Fazekas F; Seifert-Held T
Article: ACTA NEUROPATHOLOGICA. 2016;131(3):453-464
Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration
Lewandowski SA; Nilsson I; Fredriksson L; Lonnerberg P; Muhl L; Zeitelhofer M; Adzemovic MZ; Nichterwitz S; Lawrence DA; Hedlund E; Eriksson U
Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2015;107(10):djv209
Role of Tumor Pericytes in the Recruitment of Myeloid-Derived Suppressor Cells
Hong J; Tobin NP; Rundqvist H; Li T; Lavergne M; Garcia-Ibanez Y; Qin H; Paulsson J; Zeitelhofer M; Adzemovic MZ; Nilsson I; Roswall P; Hartman J; Johnson RS; Ostman A; Bergh J; Poljakovic M; Genove G
Article: NEUROBIOLOGY OF DISEASE. 2014;71:220-233
Acute treatment with valproic acid and L-thyroxine ameliorates clinical signs of experimental autoimmune encephalomyelitis and prevents brain pathology in DA rats
Castelo-Branco G; Stridh P; Guerreiro-Cacais AO; Adzemovic MZ; Falcao AM; Marta M; Berglund R; Gillett A; Hamza KH; Lassmann H; Hermanson O; Jagodic M
Article: GENES AND IMMUNITY. 2014;15(7):457-465
The multiple sclerosis risk gene IL22RA2 contributes to a more severe murine autoimmune neuroinflammation
Laaksonen H; Guerreiro-Cacais AO; Adzemovic MZ; Parsa R; Zeitelhofer M; Jagodic M; Olsson T
Article: GLIA. 2014;62(7):1066-1074
Thymic stromal lymphopoietin is expressed in the intact central nervous system and upregulated in the myelin-degenerative central nervous system.
Kitic M; Wimmer I; Adzemovic M; Kögl N; Rudel A; Lassmann H; Bradl M
Article: EXPERIMENTAL NEUROLOGY. 2013;249:39-48
Efficacy of vitamin D in treating multiple sclerosis-like neuroinflammation depends on developmental stage
Adzemovic MZ; Zeitelhofer M; Hochmeister S; Gustafsson SA; Jagodic M
Journal article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2013;333:e397-e398
A new model of focal inflammatory demyelination in the neocortex of the rat
Hochmeister S; Birngruber T; Zeitelhofer-Adzemovic M; Haindl M; Pieber TR; Sinner F
Article: PLOS ONE. 2013;8(2):e56586
Imatinib Ameliorates Neuroinflammation in a Rat Model of Multiple Sclerosis by Enhancing Blood-Brain Barrier Integrity and by Modulating the Peripheral Immune Response
Adzemovic MZ; Zeitelhofer M; Eriksson U; Olsson T; Nilsson I
Article: PLOS ONE. 2012;7(7):e39794
Expression of Ccl11 Associates with Immune Response Modulation and Protection against Neuroinflammation in Rats
Adzemovic MZ; Ockinger J; Zeitelhofer M; Hochmeister S; Beyeen AD; Paulson A; Gillett A; Hedreul MT; Covacu R; Lassmann H; Olsson T; Jagodic M
Article: JOURNAL OF IMMUNOLOGY. 2010;185(11):6883-6890
IL-22RA2 Associates with Multiple Sclerosis and Macrophage Effector Mechanisms in Experimental Neuroinflammation
Beyeen AD; Adzemovic MZ; Ockinger J; Stridh P; Becanovic K; Laaksonen H; Lassmann H; Harris RA; Hillert J; Alfredsson L; Celius EG; Harbo HF; Kockum I; Jagodic M; Olsson T
Article: PLOS ONE. 2010;5(9):e12716
Fine-Mapping Resolves Eae23 into Two QTLs and Implicates ZEB1 as a Candidate Gene Regulating Experimental Neuroinflammation in Rat
Stridh P; Hedreul MT; Beyeen AD; Adzemovic MZ; Laaksonen H; Gillett A; Ockinger J; Marta M; Lassmann H; Becanovic K; Jagodic M; Olsson T
Article: ANNALS OF NEUROLOGY. 2009;66(5):630-643
Neuromyelitis optica: pathogenicity of patient immunoglobulin in vivo.
Bradl M; Misu T; Takahashi T; Watanabe M; Mader S; Reindl M; Adzemovic M; Bauer J; Berger T; Fujihara K; Itoyama Y; Lassmann H
Article: NEUROBIOLOGY OF DISEASE. 2009;35(3):368-375
The "window of susceptibility" for inflammation in the immature central nervous system is characterized by a leaky blood-brain barrier and the local expression of inflammatory chemokines.
Schoderboeck L; Adzemovic M; Nicolussi E-M; Crupinschi C; Hochmeister S; Fischer M-T; Lassmann H; Bradl M
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Alla övriga publikationer

Editorial comment: FRONTIERS IN NEUROLOGY. 2022;13:925216
Editorial: Neuropathology of Autoimmune Inflammatory Demyelination Disorders
Zeitelhofer M; Hochmeister S; Adzemovic MZ
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:212-213
DNA methylation changes in brains from multiple sclerosis patients
Kular L; Needhamsen M; Zeitelhofer-Adzemovic M; Kramarova T; Gomez-Cabrero D; Ewing E; Piket E; Tegner J; Beck S; Piehl F; Brundin L; Jagodic M
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2018;24:848-849
Investigation of astrocytic functions and involvement in remyelination in an animal model of multiple sclerosis
Haindl MT; Koeck U; Zeitelhofer-Adzemovic M; Fazekas F; Hochmeister S
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2016;22:167
Widespread cortical demyelination of both hemispheres can be induced by injection of pro-inflammatory cytokines via an implanted catheter in the cortex of MOG-immunized rats
Hochmeister S; Uecal M; Haindl M; Zeitelhofer-Adzemovic M; Theisl L; Strasser J; Ropele S; Schaefer U; Fazekas F
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2016;22:165
Investigation of remyelination facilitating factors produced by astrocytes in an animal model of multiple sclerosis
Haindl M; Koeck U; Zeitelhofer-Adzemovic M; Storch MK; Fazekas F; Hochmeister S
Corrigendum: PLOS ONE. 2015;10(4):e0123142
Imatinib Ameliorates Neuroinflammation in a Rat Model of Multiple Sclerosis by Enhancing Blood-Brain Barrier Integrity and by Modulating the Peripheral Immune Response (vol 8, e56586, 2013)
Adzemovic ZM; Zeitelhofer M; Eriksson U; Olsson T; Nilsson I
Meeting abstract: JOURNAL OF NEUROIMMUNOLOGY. 2014;275(1-2):32
Imatinib ameliorates neuroinflammation in a rat model of multiple sclerosis by enhancing blood-brain barrier integrity and by modulating the peripheral immune response
Adzemovic MZ; Zeitelhofer M; Eriksson U; Olsson T; Nilsson I
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2013;19(11):137-138
A new model of focal inflammatory demyelination in the neocortex of the rat
Hochmeister S; Birngruber T; Zeitelhofer-Adzemovic M; Haindl M; Sinner F

Anställningar

Anknuten till Forskning, Klinisk neurovetenskap, Karolinska Institutet, 2022-2025

Examina och utbildning

Docent, neurovetenskap, Karolinska Institutet, 2021

Om mig

Forskningsbeskrivning

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

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