Mikael Lundqvist

Mikael Lundqvist

Senior Forskare
Telefon: +46852483399
Besöksadress: Nobels väg 9, 17177 Stockholm
Postadress: K8 Klinisk neurovetenskap, K8 Psykologi Lundström Lundqvist, 171 77 Stockholm

Om mig

  • Research is focused on working memory and attentions, using experimental and
    theoretical approaches. Human, non-human data is compared to network
    simulations to understand principles of cognition.

Artiklar

Alla övriga publikationer

Forskningsbidrag

  • Swedish Research Council
    1 January 2023 - 31 December 2026
    The flexible control over the contents of our working memory (WM) frees us from reflexive behavior and supports central cognitive behaviors such as planning and language comprehension. WM capacity is strongly correlated with individual intelligence and it is one of the most studied aspects of human cognition. A major limitation of previous research on visually related WM is that it has typically required experimental subjects to not move their heads or gaze to create a tightly controlled environment. In everyday life, however, gaze position constantly changes as we walk around, turn our heads, and make eye-movements. The focus of this project is to start mapping the mechanisms that underlie WM processes in real-life, dynamic environments. We will conduct a series of behavioral and EEG experiments that utilize instructed eye-movements while subjects use their WM. This will allow us to determine the impact of gaze shifts while maintaining the experimental control of classical WM experiments. We will simultaneously record behavior, EEG, and gaze shifts to allow direct inference. The goal is to understand how WM representations are transformed following gaze shifts to account for the new frame of reference, and how this impacts behavior. This will ultimately provide us with fundamental insights on how we update contents of WM to serve future behavior. The project will therefore provide important insights into the workings of working memory in real life scenarios.
  • European Research Council
    1 June 2021 - 31 May 2026
    Working memory (WM) is a fundamental cognitive capability. It refers to our ability to hold, select and manipulate several objects in mind simultaneously. It allows us to engage in flexible behavior and is tightly linked to fluid intelligence. This project will answer an essential, yet unsolved aspect of WM: How can primates use their WM in a generalized way and control what they think about? If you hear apple, stone and pear in sequence, and then you are asked to imagine the first fruit, how is it that you do not confuse apples with pears? There are many competing models of WM, but no biologically detailed models are capable of generalization. Neural networks can be trained to perform similar WM tasks as primates do, a major difference is that primates generalize their training. They can learn the task on a set of objects, then perform it on a novel set. Computational models typically rely on changing the connections between units to achieve the desired activity patterns to solve the task. Since these activity patterns depend on the objects held in WM, the training does not translate to novel objects. I propose a new solution to this problem, the Hot-Coal model of WM. It relies on a novel computational principle in which spatial location of information, rather than connectivity, is controlled by excitatory bursts to support cognition. I will explore this principle and test it in data. Preliminary tests suggest that the Hot-Coal theory is supported by electrophysiological data from primates. By implementing the theory in computational networks I aim to demonstrate the generalization mechanism and provide more detailed predictions. Finally, I will use the theory to resolve seemingly conflicting findings regarding the mechanisms underlying WM, by reproducing them in a single model. The new theory could constitute a significant advance in the mechanistic understanding of one of the most central and puzzling components of cognition.
  • Swedish Research Council
    1 January 2019 - 31 December 2022
  • Single-trial analysis in Cognition
    Brain and Behavior Research Foundation
    1 January 2018 - 1 January 2019

Anställningar

  • Senior Forskare, Klinisk neurovetenskap, Karolinska Institutet, 2022-

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