Michael Vanlandewijck

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: CIRCULATION RESEARCH. 2024;134(11):1405-1423

Single-Cell Gene-Regulatory Networks of Advanced Symptomatic Atherosclerosis

Mocci G; Sukhavasi K; Ord T; Bankier S; Singha P; Arasu UT; Agbabiaje OO; Makinen P; Ma L; Hodonsky CJ; Aherrahrou R; Muhl L; Liu J; Gustafsson S; Byandelger B; Wang Y; Koplev S; Lendahl U; Owens GK; Leeper NJ; Pasterkamp G; Vanlandewijck M; Michoel T; Ruusalepp A; Hao K; Yla-Herttuala S; Vali M; Jarve H; Mokry M; Civelek M; Miller CJ; Kovacic JC; Kaikkonen MU; Betsholtz C; Bjorkegren JLM
Article: NATURE. 2024;628(8009):863-871

A brain-specific angiogenic mechanism enabled by tip cell specialization

Schevenels G; Cabochette P; America M; Vandenborne A; De Grande L; Guenther S; He L; Dieu M; Christou B; Vermeersch M; Germano RFV; Perez-Morga D; Renard P; Martin M; Vanlandewijck M; Betsholtz C; Vanhollebeke B
Article: CELL REPORTS. 2024;43(3):113911

Mosaic deletion of claudin-5 reveals rapid non-cell-autonomous consequences of blood-brain barrier leakage

Vazquez-Liebanas E; Mocci G; Li W; Lavina B; Reddy A; O'Connor C; Hudson N; Elbeck Z; Nikoloudis I; Gaengel K; Vanlandewijck M; Campbell M; Betsholtz C; Mae MA
Article: NEURON. 2023;111(23):3745-3764.e7

Molecular anatomy of adult mouse leptomeninges

Pietila R; Del Gaudio F; He L; Vazquez-Liebanas E; Vanlandewijck M; Muhl L; Mocci G; Bjornholm KD; Lindblad C; Fletcher-Sandersjoo A; Svensson M; Thelin EP; Liu J; van Voorden AJ; Torres M; Antila S; Xin L; Karlstrom H; Storm-Mathisen J; Bergersen LH; Moggio A; Hansson EM; Ulvmar MH; Nilsson P; Makinen T; Mae MA; Alitalo K; Proulx ST; Engelhardt B; McDonald DM; Lendahl U; Andrae J; Betsholtz C
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2023;220(4):e20220741

Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation

Petkova M; Kraft M; Stritt S; Martinez-Corral I; Ortsaeter H; Vanlandewijck M; Jakic B; Baselga E; Castillo SD; Graupera M; Betsholtz C; Maekinen T
Article: CELL REPORTS: METHODS. 2023;3(3):100431

A robust and efficient microvascular isolation method for multimodal characterization of the mouse brain vasculature

Bjornholm KD; Del Gaudio F; Li H; Li W; Vazquez-Liebanas E; Mae MA; Lendahl U; Betsholtz C; Nilsson P; Karlstrom H; Vanlandewijck M
Article: DEVELOPMENTAL CELL. 2022;57(20):2426-2443.e6

A single-cell transcriptomic inventory of murine smooth muscle cells

Muhl L; Mocci G; Pietila R; Liu J; He L; Genove G; Leptidis S; Gustafsson S; Buyandelger B; Raschperger E; Hansson EM; Bjorkegren JLM; Vanlandewijck M; Lendahl U; Betsholtz C
Article: STEM CELL REPORTS. 2022;17(7):1546-1560

CD49b identifies functionally and epigenetically distinct subsets of lineage-biased hematopoietic stem cells

Somuncular E; Hauenstein J; Khalkar P; Johansson A-S; Dumral O; Frengen NS; Gustafsson C; Mocci G; Su T-Y; Brouwer H; Trautmann CL; Vanlandewijck M; Orkin SH; Mansson R; Luc S
Article: NATURE COMMUNICATIONS. 2022;13(1):3983

ADAMTS18⁺ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels

Bernier-Latmani J; Mauri C; Marcone R; Renevey F; Durot S; He L; Vanlandewijck M; Maclachlan C; Davanture S; Zamboni N; Knott GW; Luther SA; Betsholtz C; Delorenzi M; Brisken C; Petrova TV
Article: STEM CELL REPORTS. 2022;17(5):1089-1104

The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research

Muhl L; He L; Sun Y; Mae MA; Pietila R; Liu J; Genove G; Zhang L; Xie Y; Leptidis S; Mocci G; Stritt S; Osman A; Anisimov A; Hemanthakumar KA; Rasanen M; Hansson EM; Bjorkegren J; Vanlandewijck M; Blomgren K; Makinen T; Peng X-R; Hu Y; Ernfors P; Arnold TD; Alitalo K; Lendahl U; Betsholtz C
Article: EXPERIMENTAL CELL RESEARCH. 2021;402(2):112576

A human cell type similar to murine central nervous system perivascular fibroblasts

Liu J; He L; Muhl L; Mocci G; Gustavsson S; Buyandelger B; Vanlandewijck M; Betsholtz C; Westermark B; Andrae J
Article: CIRCULATION RESEARCH. 2021;128(4):e46-e62

Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss

Mae MA; He L; Nordling S; Vazquez-Liebanas E; Nahar K; Jung B; Li X; Tan BC; Foo JC; Cazenave-Gassiot A; Wenk MR; Zarb Y; Lavina B; Quaggin SE; Jeansson M; Gu C; Silver DL; Vanlandewijck M; Butcher EC; Keller A; Betsholtz C
Article: DISEASE MODELS & MECHANISMS. 2021;14(2):dmm046300

The infantile myofibromatosis NOTCH3 L1519P mutation leads to hyperactivated ligand-independent Notch signaling and increased PDGFRB expression

Wu D; Wang S; Oliveira DV; Del Gaudio F; Vanlandewijck M; Lebouvier T; Betsholtz C; Zhao J; Jin S; Lendahl U; Karlstrom H
Article: NATURE COMMUNICATIONS. 2020;11(1):3953

Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination

Muhl L; Genove G; Leptidis S; Liu J; He L; Mocci G; Sun Y; Gustafsson S; Buyandelger B; Chivukula IV; Segerstolpe A; Raschperger E; Hansson EM; Bjorkegren JLM; Peng X-R; Vanlandewijck M; Lendahl U; Betsholtz C
Article: BRAIN PATHOLOGY. 2020;30(3):446-464

Astrocyte-microglial association and matrix composition are common events in the natural history of primary familial brain calcification

Nahar K; Lebouvier T; Mae MA; Konzer A; Bergquist J; Zarb Y; Johansson B; Betsholtz C; Vanlandewijck M
Article: ELIFE. 2020;9:e52690

Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta

Engelbrecht E; Levesque MV; He L; Vanlandewijck M; Nitzsche A; Niazi H; Kuo A; Singh SA; Aikawa M; Holton K; Proia RL; Kono M; Pu WT; Camerer E; Betsholtz C; Hla T
Article: NATURE COMMUNICATIONS. 2020;11(1):71

Integrative discovery of treatments for high-risk neuroblastoma

Almstedt E; Elgendy R; Hekmati N; Rosen E; Warn C; Olsen TK; Dyberg C; Doroszko M; Larsson I; Sundstrom A; Henriksson MA; Pahlman S; Bexell D; Vanlandewijck M; Kogner P; Jornsten R; Krona C; Nelander S
Article: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2020;7:52

A Single-Cell Transcriptional Roadmap of the Mouse and Human Lymph Node Lymphatic Vasculature

Xiang M; Grosso RA; Takeda A; Pan J; Bekkhus T; Brulois K; Dermadi D; Nordling S; Vanlandewijck M; Jalkanen S; Ulvmar MH; Butcher EC
Article: SCIENTIFIC REPORTS. 2019;9(1):203

Claudin-3-deficient C57BL/6J mice display intact brain barriers

Dias MC; Coisne C; Lazarevic I; Baden P; Hata M; Iwamoto N; Francisco DMF; Vanlandewijck M; He L; Baier FA; Stroka D; Bruggmann R; Lyck R; Enzmann G; Deutsch U; Betsholtz C; Furuse M; Tsukita S; Engelhardt B
Article: SCIENTIFIC REPORTS. 2018;8(1):17462

Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier

Mae MA; Li T; Bertuzzi G; Raschperger E; Vanlandewijck M; He L; Nahar K; Dalheim A; Hofmann JJ; Lavina B; Keller A; Betsholtz C; Genove G
Article: SCIENTIFIC DATA. 2018;5:180160

Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

He L; Vanlandewijck M; Mae MA; Andrae J; Ando K; Del Gaudio F; Nahar K; Lebouvier T; Lavina B; Gouveia L; Sun Y; Raschperger E; Segerstolpe A; Liu J; Gustafsson S; Rasanen M; Zarb Y; Mochizuki N; Keller A; Lendahl U; Betsholtz C
Article: NATURE. 2018;554(7693):475-480

A molecular atlas of cell types and zonation in the brain vasculature

Vanlandewijck M; He L; Mae MAA; Andrae J; Ando K; Del Gaudio F; Nahar K; Lebouvier T; Lavina B; Gouveia L; Sun Y; Raschperger E; Rasanen M; Zarb Y; Mochizuki N; Keller A; Lendahl U; Betsholtz C
Article: ONCOTARGET. 2018;9(5):5716-5735

The protein kinase SIK downregulates the polarity protein Par3.

Vanlandewijck M; Dadras MS; Lomnytska M; Mahzabin T; Lee Miller M; Busch C; Brunak S; Heldin C-H; Moustakas A
Article: METHODS IN MOLECULAR BIOLOGY. 2018;1846:309-324

Single-Cell mRNA Sequencing of the Mouse Brain Vasculature.

Vanlandewijck M; Betsholtz C
Article: PLOS ONE. 2018;13(1):e0189433

Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice

Loganathan K; Said ES; Winterrowd E; Orebrand M; He L; Vanlandewijck M; Betsholtz C; Quaggin SE; Jeansson M
Article: SCIENTIFIC REPORTS. 2017;7(1):15453

Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema

Egana I; Kaito H; Nitzsche A; Becker L; Ballester-Lopez C; Niaudet C; Petkova M; Liu W; Vanlandewijck M; Vernaleken A; Klopstock T; Fuchs H; Gailus-Durner V; de Angelis MH; Rask-Andersen H; Johansson HJ; Lehtio J; He L; Yildirim AO; Hellstrom M
Article: SCIENTIFIC REPORTS. 2016;6:35108

Analysis of the brain mural cell transcriptome

He L; Vanlandewijck M; Raschperger E; Mae MA; Jung B; Lebouvier T; Ando K; Hofmann J; Keller A; Betsholtz C
Article: SCIENTIFIC REPORTS. 2016;6:29868

Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation

Carthy JM; Stoeter M; Bellomo C; Vanlandewijck M; Heldin A; Moren A; Kardassis D; Gahman TC; Shiau AK; Bickle M; Zerial M; Heldin C-H; Moustakas A
Article: PLOS ONE. 2015;10(11):e0143407

Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification

Vanlandewijck M; Lebouvier T; Mae MA; Nahar K; Hornemann S; Kenkel D; Cunha SI; Lennartsson J; Boss A; Heldin C-H; Keller A; Betsholtz C
Article: PLOS ONE. 2015;10(9):e0137949

Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium

Niaudet C; Hofmann JJ; Mae MA; Jung B; Gaengel K; Vanlandewijck M; Ekvarn E; Salvado MD; Mehlem A; Al Sayegh S; He L; Lebouvier T; Castro-Freire M; Katayama K; Hultenby K; Moessinger C; Tannenberg P; Cunha S; Pietras K; Lavina B; Hong J; Berg T; Betsholtz C
Article: PLOS ONE. 2014;9(8):e103651

Fine-Tuning of Smad Protein Function by Poly(ADP-Ribose) Polymerases and Poly(ADP-Ribose) Glycohydrolase during Transforming Growth Factor β Signaling

Dahl M; Maturi V; Lonn P; Papoutsoglou P; Zieba A; Vanlandewijck M; van der Heide LP; Watanabe Y; Soderberg O; Hottiger MO; Heldin C-H; Moustakas A
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(16):12867-12878

Transcriptional Induction of Salt-inducible Kinase 1 by Transforming Growth Factor β Leads to Negative Regulation of Type I Receptor Signaling in Cooperation with the Smurf2 Ubiquitin Ligase

Lonn P; Vanlandewijck M; Raja E; Kowanetz M; Watanabe Y; Kowanetz K; Vasilaki E; Heldin C-H; Moustakas A
Article: JOURNAL OF CELL BIOLOGY. 2008;182(4):655-662

TGFβ induces SIK to negatively regulate type I receptor kinase signaling

Kowanetz M; Loenn P; Vanlandewijck M; Kowanetz K; Heldin C-H; Moustakas A
Article: JOURNAL OF CELL BIOLOGY. 2007;176(5):695-707

Notch signaling is necessary for epithelial growth arrest by TGF-β

Niimi H; Pardali K; Vanlandewijck M; Heldin C-H; Moustakas A
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Review: CARDIOVASCULAR RESEARCH. 2019;115(12):1705-1715

Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single-cell sequencing

van Kuijk K; Kuppe C; Betsholtz C; Vanlandewijck M; Kramann R; Sluimer JC
Review: FEBS LETTERS. 2012;586(14):1959-1970

Regulation of EMT by TGFβ in cancer

Heldin C-H; Vanlandewijck M; Moustakas A

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