Michael Landreh

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Artiklar

Article: ADVANCED FUNCTIONAL MATERIALS. 2024;34(23)

Spiders Use Structural Conversion of Globular Amyloidogenic Domains to Make Strong Silk Fibers

Qi X; Wang H; Wang K; Wang Y; Leppert A; Iashchishyn I; Zhong X; Zhou Y; Liu R; Rising A; Landreh M; Johansson J; Chen G
Article: CELL. 2024;187(6):1440-1459.e24

ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat

Nishio S; Emori C; Wiseman B; Fahrenkamp D; Dioguardi E; Zamora-Caballero S; Bokhove M; Han L; Stsiapanava A; Algarra B; Lu Y; Kodani M; Bainbridge RE; Komondor KM; Carlson AE; Landreh M; Sanctis DD; Yasumasu S; Ikawa M; Jovine L
Article: NATURE COMMUNICATIONS. 2024;15(1):1865

A druggable conformational switch in the c-MYC transactivation domain

Lama D; Vosselman T; Sahin C; Liano-Pons J; Cerrato CP; Nilsson L; Teilum K; Lane DP; Landreh M; Arsenian Henriksson M
Article: NATURE PROTOCOLS. 2023;18(12):3653-3661

Advances in mass spectrometry to unravel the structure and function of protein condensates

Sahin C; Leppert A; Landreh M
Article: TRANSLATIONAL RESEARCH. 2023;262:60-74

Synthetic surfactant with a combined SP-B and SP-C analogue is efficient in rabbit models of adult and neonatal respiratory distress syndrome

Mikolka P; Kronqvist N; Haegerstrand-Bjorkman M; Jaudzems K; Kosutova P; Kolomaznik M; Saluri M; Landreh M; Calkovska A; Curstedt T; Johansson J
Article: NATURE COMMUNICATIONS. 2023;14(1):7636

The heat shock protein LarA activates the Lon protease in response to proteotoxic stress

Omnus DJ; Fink MJ; Kallazhi A; Xandri Zaragoza M; Leppert A; Landreh M; Jonas K
Article: CELL REPORTS: METHODS. 2023;3(11):100626

Dual stop codon suppression in mammalian cells with genomically integrated genetic code expansion machinery

Meineke B; Heimgartner J; Caridha R; Block MF; Kimler KJ; Pires MF; Landreh M; Elsasser SJ
Article: SMALL. 2023;19(46)

Spider Silk Protein Forms Amyloid-Like Nanofibrils through a Non-Nucleation-Dependent Polymerization Mechanism (Small 46/2023)

Qi X; Wang Y; Yu H; Liu R; Leppert A; Zheng Z; Zhong X; Jin Z; Wang H; Li X; Wang X; Landreh M; Morozova-Roche LA; Johansson J; Xiong S; Iashchishyn I; Chen G
Article: SMALL. 2023;19(46):e2304031

Spider Silk Protein Forms Amyloid-Like Nanofibrils through a Non-Nucleation-Dependent Polymerization Mechanism

Qi X; Wang Y; Yu H; Liu R; Leppert A; Zheng Z; Zhong X; Jin Z; Wang H; Li X; Wang X; Landreh M; Morozova-Roche LA; Johansson J; Xiong S; Iashchishyn I; Chen G
Article: ANALYTICAL CHEMISTRY. 2023;95(29):10869-10872

Monitoring Disassembly and Cargo Release of Phase-Separated Peptide Coacervates with Native Mass Spectrometry

Cerrato CPP; Leppert A; Sun Y; Lane DPP; Arsenian-Henriksson M; Miserez A; Landreh M
Article: NATURE COMMUNICATIONS. 2023;14(1):4070

Establishing mammalian GLUT kinetics and lipid composition influences in a reconstituted-liposome system

Suades A; Qureshi A; McComas SE; Coincon M; Rudling A; Chatzikyriakidou Y; Landreh M; Carlsson J; Drew D
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2023;145(19):10659-10668

Mass Spectrometry of RNA-Binding Proteins during Liquid-Liquid Phase Separation Reveals Distinct Assembly Mechanisms and Droplet Architectures

Sahin C; Motso A; Gu X; Feyrer H; Lama D; Arndt T; Rising A; Gese GV; Haellberg BM; Marklund EG; Schafer NP; Petzold K; Teilum K; Wolynes PG; Landreh M
Article: PNAS NEXUS. 2023;2(2):pgac303

A "grappling hook" interaction connects self-assembly and chaperone activity of Nucleophosmin 1

Saluri M; Leppert A; Gese GV; Sahin C; Lama D; Kaldmae M; Chen G; Elofsson A; Allison TM; Arsenian-Henriksson M; Johansson J; Lane DP; Hallberg BM; Landreh M
Article: MOLECULAR & CELLULAR PROTEOMICS. 2022;21(10):100413

Mass Spectrometry and Machine Learning Reveal Determinants of Client Recognition by Antiamyloid Chaperones

Osterlund N; Vosselman T; Leppert A; Graslund A; Jornvall H; Ilag LL; Marklund EG; Elofsson A; Johansson J; Sahin C; Landreh M
Article: NATURE COMMUNICATIONS. 2022;13(1):4695

Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform

Arndt T; Jaudzems K; Shilkova O; Francis J; Johansson M; Laity PR; Sahin C; Chatterjee U; Kronqvist N; Barajas-Ledesma E; Kumar R; Chen G; Stromberg R; Abelein A; Langton M; Landreh M; Barth A; Holland C; Johansson J; Rising A
Article: PROTEIN SCIENCE. 2022;31(8):e4378

ATP-independent molecular chaperone activity generated under reducing conditions

Leppert A; Chen G; Lianoudaki D; Williams C; Zhong X; Gilthorpe JD; Landreh M; Johansson J
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2022;144(27):11949-11954

Structural Basis for Dityrosine-Mediated Inhibition of α-Synuclein Fibrillization

Sahin C; Osterlund EC; Osterlund N; Costeira-Paulo J; Pedersen JN; Christiansen G; Nielsen J; Gronnemose AL; Amstrup SK; Tiwari MK; Rao RSP; Bjerrum MJ; Ilag LL; Davies MJ; Marklund EG; Pedersen JS; Landreh M; Moller IM; Jorgensen TJD; Otzen DE
Article: PROTEIN SCIENCE. 2022;31(6):e4333

Complementing machine learning-based structure predictions with native mass spectrometry

Allison TM; Degiacomi MT; Marklund EG; Jovine L; Elofsson A; Benesch JLP; Landreh M
Article: STRUCTURE. 2022;30(5):733-742.e7

A "spindle and thread"mechanism unblocks p53 translation N-terminal disorder

Kaldmae M; Vosselman T; Zhong X; Lama D; Chen G; Saluri M; Kronqvist N; Siau JW; Ng AS; Ghadessy FJ; Sabatier P; Vojtesek B; Sarr M; Sahin C; Osterlund N; Ilag LL; Vaananen VA; Sedimbi S; Arsenian-Henriksson M; Zubarev RA; Nilsson L; Koeck PJB; Rising A; Abelein A; Fritz N; Johansson J; Lane DP; Landreh M
Article: RSC ADVANCES. 2022;12(16):9671-9680

Electrospray ionization of native membrane proteins proceeds via a charge equilibration step

Yen H-Y; Abramsson ML; Agasid MT; Lama D; Gault J; Liko I; Kaldmae M; Saluri M; Qureshi AA; Suades A; Drew D; Degiacomi MT; Marklund EG; Allison TM; Robinson CV; Landreh M
Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2022;29(2):108-120

Structure, mechanism and lipid-mediated remodeling of the mammalian Na⁺/H⁺ exchanger NHA2

Matsuoka R; Fudim R; Jung S; Zhang C; Bazzone A; Chatzikyriakidou Y; Robinson CV; Nomura N; Iwata S; Landreh M; Orellana L; Beckstein O; Drew D
Article: JACS AU. 2021;1(12):2385-2393

Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry

Abramsson ML; Sahin C; Hopper JTS; Branca RMM; Danielsson J; Xu M; Chandler SA; Osterlund N; Ilag LL; Leppert A; Costeira-Paulo J; Lang L; Teilum K; Laganowsky A; Benesch JLP; Oliveberg M; Robinson CV; Marklund EG; Allison TM; Winther JR; Landreh M
Article: ACS CHEMICAL BIOLOGY. 2021;16(12):2864-2873

Treatment of Respiratory Distress Syndrome with Single Recombinant Polypeptides that Combine Features of SP-B and SP-C

Basabe-Burgos O; Landreh M; Rising A; Curstedt T; Johansson J
Article: CELL CHEMICAL BIOLOGY. 2021;28(9):1321-1332.e5

N-Thio-β-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis

Martelli G; Pessatti TB; Steiner EM; Cirillo M; Caso C; Bisognin F; Landreh M; Dal Monte P; Giacomini D; Schnell R
Article: SCIENCE ADVANCES. 2021;7(27):eabh3805

Order and disorder-An integrative structure of the full-length human growth hormone receptor

Kassem N; Araya-Secchi R; Bugge K; Barclay A; Steinocher H; Khondker A; Wang Y; Lenard AJ; Buerck J; Sahin C; Ulrich AS; Landreh M; Pedersen MC; Rheinstaedter MC; Pedersen PA; Lindorff-Larsen K; Arleth L; Kragelund BB
Article: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2021;198:113996

The synthesis and characterization of Bri2 BRICHOS coated magnetic particles and their application to protein fishing: Identification of novel binding proteins

Tigro H; Kronqvist N; Abelein A; Galan-Acosta L; Chen G; Landreh M; Lyashkov A; Aon MA; Ferrucci L; Shimmo R; Johansson J; Moaddel R
Article: BIOCHEMISTRY. 2021;60(9):678-688

Smallest Secondary Nucleation Competent Aβ Aggregates Probed by an ATP-Independent Molecular Chaperone Domain

Leppert A; Tiiman A; Kronqvist N; Landreh M; Abelein A; Vukojevic V; Johansson J
Article: CHEMICAL COMMUNICATIONS. 2021;57(12):1450-1453

Ion mobility-mass spectrometry shows stepwise protein unfolding under alkaline conditions

Sahin C; Osterlund N; Leppert A; Johansson J; Marklund EG; Benesch JLP; Ilag LL; Allison TM; Landreh M
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2021;78(3):1131-1138

Biological activity versus physiological function of proinsulin C-peptide

Landreh M; Jornvall H
Article: FRONTIERS IN CHEMISTRY. 2021;9:768535

A Genetically Encoded Picolyl Azide for Improved Live Cell Copper Click Labeling

Meineke B; Heimgartner J; Craig AJ; Landreh M; Moodie LWK; Elsasser SJ
Article: EMBO JOURNAL. 2020;39(24):e105908-4559

Structure and elevator mechanism of the mammalian sodium/proton exchanger NHE9

Winklemann I; Matsuoka R; Meier PF; Shutin D; Zhang C; Orellana L; Sexton R; Landreh M; Robinson CV; Beckstein O; Drew D
Article: ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS. 2020;52:102058

Spatial variation and structural characteristics of phycobiliproteins from the red algae Furcellaria lumbricalis and Coccotylus truncatus

Saluri M; Kaldmae M; Rospu M; Sirkel H; Paalme T; Landreh M; Tuvikene R
Article: ANALYTICAL CHEMISTRY. 2020;92(18):12297-12303

Predicting the Shapes of Protein Complexes through Collision Cross Section Measurements and Database Searches

Landreh M; Sahin C; Gault J; Sadeghi S; Drum CL; Uzdavinys P; Drew D; Allison TM; Degiacomi MT; Marklund EG
Article: FEBS JOURNAL. 2020;287(13):2823-2833

High intracellular stability of the spidroin N-terminal domain in spite of abundant amyloidogenic segments revealed by in-cell hydrogen/deuterium exchange mass spectrometry

Kaldmae M; Leppert A; Chen G; Sarr M; Sahin C; Nordling K; Kronqvist N; Gonzalvo-Ulla M; Fritz N; Abelein A; Lain S; Biverstal H; Jornvall H; Lane DP; Rising A; Johansson J; Landreh M
Article: CELL REPORTS. 2020;31(12):107811

Site-Specific Incorporation of Two ncAAs for Two-Color Bioorthogonal Labeling and Crosslinking of Proteins on Live Mammalian Cells

Meineke B; Heimgertner J; Eirich J; Landreh M; Elsasser SJ
Article: NATURE METHODS. 2020;17(5):505-508

Combining native and 'omics' mass spectrometry to identify endogenous ligands bound to membrane proteins

Gault J; Liko I; Landreh M; Shutin D; Bolla JR; Jefferies D; Agasid M; Yen H-Y; Ladds MJGW; Lane DP; Khalid S; Mullen C; Remes PM; Huguet R; McAlister G; Goodwin M; Viner R; Syka JEP; Robinson CV
Article: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2020;59(9):3523-3528

A Mass-Spectrometry-Based Approach to Distinguish Annular and Specific Lipid Binding to Membrane Proteins

Bolla JR; Corey RA; Sahin C; Gault J; Hummer A; Hopper JTS; Lane DP; Drew D; Allison TM; Stansfeld PJ; Robinson CV; Landreh M
Article: SCIENTIFIC REPORTS. 2020;10(1):2376

Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties

Al-Adwani S; Wallin C; Balhuizen MD; Veldhuizen EJA; Coorens M; Landreh M; Vegvari A; Smith ME; Qvarfordt I; Linden A; Graslund A; Agerberth B; Bergman P
Article: COMMUNICATIONS BIOLOGY. 2020;3(1):32

Augmentation of Bri2 molecular chaperone activity against amyloid-β reduces neurotoxicity in mouse hippocampus in vitro

Chen G; Andrade-Talavera Y; Tambaro S; Leppert A; Nilsson HE; Zhong X; Landreh M; Nilsson P; Hebert H; Biverstal H; Fisahn A; Abelein A; Johansson J
Article: SCIENTIFIC REPORTS. 2020;10(1):235

High-yield Production of Amyloid-β Peptide Enabled by a Customized Spider Silk Domain

Abelein A; Chen G; Kitoka K; Aleksis R; Oleskovs F; Sarr M; Landreh M; Pahnke J; Nordling K; Kronqvist N; Jaudzems K; Rising A; Johansson J; Biverstal H
Article: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY. 2019;30(8):1385-1388

Gas-Phase Collisions with Trimethylamine-N-Oxide Enable Activation-Controlled Protein Ion Charge Reduction

Kaldmae M; Osterlund N; Lianoudaki D; Sahin C; Bergman P; Nyman T; Kronqvist N; Ilag LL; Allison TM; Marklund EG; Landreh M
Article: PROTEIN SCIENCE. 2019;28(6):1024-1030

A strategy for the identification of protein architectures directly from ion mobility mass spectrometry data reveals stabilizing subunit interactions in light harvesting complexes

Kaldmae M; Sahin C; Saluri M; Marklund EG; Landreh M
Article: PLOS ONE. 2019;14(12):e0226072

Efficient delipidation of a recombinant lung surfactant lipopeptide analogue by liquid-gel chromatography

Basabe-Burgos O; Ahlstrom JZ; Mikolka P; Landreh M; Johansson J; Curstedt T; Rising A
Article: NATURE COMMUNICATIONS. 2018;9(1):4253

An engineered thermal-shift screen reveals specific lipid preferences of eukaryotic and prokaryotic membrane proteins

Nji E; Chatzikyriakidou Y; Landreh M; Drew D
Article: JOURNAL OF PHYSICAL CHEMISTRY LETTERS. 2018;9(14):4082-4086

Mass Spectrometry Reveals the Direct Action of a Chemical Chaperone

Gault J; Lianoudaki D; Kaldmae M; Kronqvist N; Rising A; Johansson J; Lohkamp B; Lain S; Allison TM; Lane DP; Marklund EG; Landreh M
Article: CELL CHEMICAL BIOLOGY. 2018;25(3):309-317.e4

Lipids Shape the Electron Acceptor-Binding Site of the Peripheral Membrane Protein Dihydroorotate Dehydrogenase

Costeira-Paulo J; Gault J; Popova G; Ladds MJGW; van Leeuwen IMM; Sarr M; Olsson A; Lane DP; Lain S; Marklund EG; Landreh M
Article: NATURE COMMUNICATIONS. 2017;8(1):2081

Bri2 BRICHOS client specificity and chaperone activity are governed by assembly state

Chen G; Abelein A; Nilsson HE; Leppert A; Andrade-Talavera Y; Tambaro S; Hemmingsson L; Roshan F; Landreh M; Biverstal H; Koeck PJB; Presto J; Hebert H; Fisahn A; Johansson J
Article: ANALYTICAL CHEMISTRY. 2017;89(14):7425-7430

Effects of Detergent Micelles on Lipid Binding to Proteins in Electrospray Ionization Mass Spectrometry

Landreh M; Costeira-Paulo J; Gault J; Marklund EG; Robinson CV
Article: NATURE COMMUNICATIONS. 2017;8:15504

Efficient protein production inspired by how spiders make silk

Kronqvist N; Sarr M; Lindqvist A; Nordling K; Otikovs M; Venturi L; Pioselli B; Purhonen P; Landreh M; Biverstal H; Toleikis Z; Sjoberg L; Robinson CV; Pelizzi N; Jornvall H; Hebert H; Jaudzems K; Curstedt T; Rising A; Johansson J
Article: CHEMICAL COMMUNICATIONS. 2017;53(23):3319-3322

Mass spectrometry captures structural intermediates in protein fiber self-assembly

Landreh M; Andersson M; Marklund EG; Jia Q; Meng Q; Johansson J; Robinson CV; Rising A
Article: NATURE CHEMICAL BIOLOGY. 2017;13(3):262-264

Biomimetic spinning of artificial spider silk from a chimeric minispidroin

Andersson M; Jia Q; Abella A; Lee X-Y; Landreh M; Purhonen P; Hebert H; Tenje M; Robinson CV; Meng Q; Plaza GR; Johansson J; Rising A
Article: NATURE. 2017;541(7637):421-424

The role of interfacial lipids in stabilizing membrane protein oligomers.

Gupta K; Donlan JAC; Hopper JTS; Uzdavinys P; Landreh M; Struwe WB; Drew D; Baldwin AJ; Stansfeld PJ; Robinson CV
Article: NATURE COMMUNICATIONS. 2017;8:13993

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters.

Landreh M; Marklund EG; Uzdavinys P; Degiacomi MT; Coincon M; Gault J; Gupta K; Liko I; Benesch JLP; Drew D; Robinson CV
Article: EMBO JOURNAL. 2016;35(18):1963-1978

A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease

Villaescusa JC; Li B; Toledo EM; Cervo PRDV; Yang S; Stott SRW; Kaiser K; Islam S; Gyllborg D; Laguna-Goya R; Landreh M; Lonnerberg P; Falk A; Bergman T; Barker RA; Linnarsson S; Selleri L; Arenas E
Article: CURRENT OPINION IN STRUCTURAL BIOLOGY. 2016;39:54-60

A sliding selectivity scale for lipid binding to membrane proteins.

Landreh M; Marty MT; Gault J; Robinson CV
Article: ANALYTICAL CHEMISTRY. 2016;88(11):5879-5884

Low Charge and Reduced Mobility of Membrane Protein Complexes Has Implications for Calibration of Collision Cross Section Measurements.

Allison TM; Landreh M; Benesch JLP; Robinson CV
Article: CHEMICAL COMMUNICATIONS. 2015;51(85):15582-15584

Controlling release, unfolding and dissociation of membrane protein complexes in the gas phase through collisional cooling.

Landreh M; Liko I; Uzdavinys P; Coincon M; Hopper JTS; Drew D; Robinson CV
Article: CHEMBIOCHEM. 2015;16(12):1720-1724

Diversified Structural Basis of a Conserved Molecular Mechanism for pH-Dependent Dimerization in Spider Silk N-Terminal Domains

Otikovs M; Chen G; Nordling K; Landreh M; Meng Q; Joernvall H; Kronqvist N; Rising A; Johansson J; Jaudzems K
Article: CHEMICO-BIOLOGICAL INTERACTIONS. 2015;234:75-79

Alcohol dehydrogenase, SDR and MDR structural stages, present update and altered era

Jornvall H; Landreh M; Ostberg LJ
Article: FEBS LETTERS. 2015;589(4):415-418

C-peptide evolution: Generation from few structural restrictions of bioactivities not necessarily functional

Landreh M; Jornvall H
Article: HUMAN REPRODUCTION. 2015;30(2):256-267

Derivation and characterization of a cytocompatible scaffold from human testis

Baert Y; Stukenborg J-B; Landreh M; De Kock J; Jornvall H; Soder O; Goossens E
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2014;450(4):1433-1438

A subdivided molecular architecture with separate features and stepwise emergence among proinsulin C-peptides

Landreh M; Ostberg LJ; Jornvall H
Article: PLOS BIOLOGY. 2014;12(8):e1001921

Carbonic Anhydrase Generates CO₂ and H⁺ That Drive Spider Silk Formation Via Opposite Effects on the Terminal Domains

Andersson M; Chen G; Otikovs M; Landreh M; Nordling K; Kronqvist N; Westermark P; Jornvall H; Knight S; Ridderstrale Y; Holm L; Meng Q; Jaudzems K; Chesler M; Johansson J; Rising A
Article: BIOMOLECULAR CONCEPTS. 2014;5(3):257-264

Transthyretin microheterogeneity and molecular interactions: implications for amyloid formation.

Landreh M; Ostberg LJ; Pettersson TM; Jörnvall H
Article: JOURNAL OF MOLECULAR BIOLOGY. 2014;426(11):2159-2166

Separate Molecular Determinants in Amyloidogenic and Antimicrobial Peptides

Landreh M; Johansson J; Jornvall H
Article: ANALYTICAL CHEMISTRY. 2014;86(9):4135-4139

Protective Effects of Dimethyl Sulfoxide on Labile Protein Interactions during Electrospray Ionization

Landreh M; Alvelius G; Johansson J; Jornvall H
Article: RAPID COMMUNICATIONS IN MASS SPECTROMETRY. 2014;28(2):178-184

Insulin, islet amyloid polypeptide and C-peptide interactions evaluated by mass spectrometric analysis

Landreh M; Alvelius G; Johansson J; Jornvall H
Article: NATURE COMMUNICATIONS. 2014;5:3254

Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation

Kronqvist N; Otikovs M; Chmyrov V; Chen G; Andersson M; Nordling K; Landreh M; Sarr M; Jornvall H; Wennmalm S; Widengren J; Meng Q; Rising A; Otzen D; Knight SD; Jaudzems K; Johansson J
Article: HORMONE AND METABOLIC RESEARCH. 2013;45(11):769-773

C-Peptide: A Molecule Balancing Insulin States in Secretion and Diabetes-associated Depository Conditions

Landreh M; Johansson J; Jornvall H
Article: FEBS JOURNAL. 2012;279(24):4589-4597

Insulin solubility transitions by pH-dependent interactions with proinsulin C-peptide

Landreh M; Alvelius G; Willander H; Stukenborg J-B; Soder O; Johansson J; Jornvall H
Article: JOURNAL OF MOLECULAR BIOLOGY. 2012;422(4):477-487

pH-Dependent Dimerization of Spider Silk N-Terminal Domain Requires Relocation of a Wedged Tryptophan Side Chain

Jaudzems K; Askarieh G; Landreh M; Nordling K; Hedhammar M; Jornvall H; Rising A; Knight SD; Johansson J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;418(3):489-493

Proinsulin C-peptide interferes with insulin fibril formation

Landreh M; Stukenborg J-B; Willander H; Soder O; Johansson J; Jornvall H
Article: NATURE. 2012;482(7386):519-523

The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila.

Liu N; Landreh M; Cao K; Abe M; Hendriks G-J; Kennerdell JR; Zhu Y; Wang L-S; Bonini NM
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(7):2325-2329

High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C

Willander H; Askarieh G; Landreh M; Westermark P; Nordling K; Keranen H; Hermansson E; Hamvas A; Nogee LM; Bergman T; Saenz A; Casals C; Aqvist J; Jornvall H; Berglund H; Presto J; Knight SD; Johansson J
Article: MOLECULAR & CELLULAR PROTEOMICS. 2011;10(9):M110.006510

A Membrane Cell for On-line Hydrogen/Deuterium Exchange to Study Protein Folding and Protein-Protein Interactions by Mass Spectrometry

Astorga-Wells J; Landreh M; Johansson J; Bergman T; Jornvall H
Article: JOURNAL OF MOLECULAR BIOLOGY. 2010;404(2):328-336

A pH-Dependent Dimer Lock in Spider Silk Protein

Landreh M; Askarieh G; Nordling K; Hedhammar M; Rising A; Casals C; Astorga-Wells J; Alvelius G; Knight SD; Johansson J; Joernvall H; Bergman T
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):2-6

Amino acid sequence determinants and molecular chaperones in amyloid fibril formation

Nerelius C; Fitzen M; Johansson J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;393(3):356-361

The extracellular domain of Bri2 (ITM2B) binds the ABri peptide (1-23) and amyloid β-peptide (Aβ1-40): Implications for Bri2 effects on processing of amyloid precursor protein and Aβ aggregation

Peng S; Fitzen M; Jornvall H; Johansson J
Article: JOURNAL OF IMMUNOLOGY. 2010;184(2):975-983

Surfactant Protein B Propeptide Contains a Saposin-Like Protein Domain with Antimicrobial Activity at Low pH

Yang L; Johansson J; Ridsdale R; Willander H; Fitzen M; Akinbi HT; Weaver TE
Article: RAPID COMMUNICATIONS IN MASS SPECTROMETRY. 2009;23(22):3591-3598

Peptide-binding specificity of the prosurfactant protein C Brichos domain analyzed by electrospray ionization mass spectrometry

Fitzen M; Alvelius G; Nordling K; Jornvall H; Bergman T; Johansson J
Article: CARBOHYDRATE RESEARCH. 2009;344(12):1567-1574

Specificity of ligand binding to yeast hexokinase PII studied by STD-NMR.

Blume A; Fitzen M; Benie AJ; Peters T
Visa fler

Alla övriga publikationer

Letter: NANO LETTERS. 2023;23(12):5836-5841

Liquid-Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain

Leppert A; Chen G; Lama D; Sahin C; Railaite V; Shilkova O; Arndt T; Marklund EG; Lane DP; Rising A; Landreh M
Review: PROTEIN SCIENCE. 2023;32(6):e4645

A new kid in the folding funnel: Molecular chaperone activities of the BRICHOS domain

Leppert A; Poska H; Landreh M; Abelein A; Chen G; Johansson J
Corrigendum: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2023;30(4):565

Structure, mechanism and lipid-mediated remodeling of the mammalian Na⁺/H⁺ exchanger NHA2 (vol 29, pg 108, 2022)

Matsuoka R; Fudim R; Jung S; Zhang C; Bazzone A; Chatzikyriakidou Y; Robinson CV; Nomura N; Iwata S; Landreh M; Orellana L; Beckstein O; Drew D
Editorial comment: JOURNAL OF BIOLOGICAL CHEMISTRY. 2022;298(5):101913

The dimerization mechanism of the N-terminal domain of spider silk proteins is conserved despite extensive sequence divergence

Sarr M; Kitoka K; Walsh-White K-A; Kaldmaee M; Metlans R; Tars K; Mantese A; Shan D; Landreh M; Rising A; Johansson J; Jaudzems K; Kronqvist N
Review: BIOCHEMICAL SOCIETY TRANSACTIONS. 2020;48(2):547-558

Scratching the surface: native mass spectrometry of peripheral membrane protein complexes

Sahin C; Reid DJ; Marty MT; Landreh M
Review: JOURNAL OF INTERNAL MEDICINE. 2016;280(2):164-176

The formation, function and regulation of amyloids: insights from structural biology.

Landreh M; Sawaya MR; Hipp MS; Eisenberg DS; Wüthrich K; Hartl FU
Review: JOURNAL OF BIOLOGICAL CHEMISTRY. 2015;290(44):26430-26436

Specific Chaperones and Regulatory Domains in Control of Amyloid Formation

Landreh M; Rising A; Presto J; Jornvall H; Johansson J
Review: JOURNAL OF PHYSIOLOGY-LONDON. 2015;593(2):355-362

A new window into the molecular physiology of membrane proteins.

Landreh M; Robinson CV
Review: BIOMOLECULAR CONCEPTS. 2014;5(2):109-118

The structure, molecular interactions and bioactivities of proinsulin C-peptide correlate with a tripartite molecule.

Landreh M; Johansson J; Wahren J; Jörnvall H
Thesis / dissertation: 2012

Molecular mechanisms of amyloid self-regulation

Landreh, Michael
Review: BIOCHEMICAL JOURNAL. 2012;447(2):185-192

Control of amyloid assembly by autoregulation

Landreh M; Johansson J; Rising A; Presto J; Jornvall H
Review: FEBS JOURNAL. 2011;278(20):3815-3821

New developments in protein structure-function analysis by MS and use of hydrogen-deuterium exchange microfluidics

Landreh M; Astorga-Wells J; Johansson J; Bergman T; Jornvall H

Anställningar

Senior Forskare, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2022-

Examina och utbildning

Docent, Cell- och molekylärbiologi, Karolinska Institutet, 2022
Medicine Doktorsexamen, Institutionen för medicinsk biokemi och biofysik, Karolinska Institutet, 2012

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