Marie Björnholm

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: ISCIENCE. 2023;26(3):106251
Exercise-acclimated microbiota improves skeletal muscle metabolism via circulating bile acid deconjugation
Aoi W; Inoue R; Mizushima K; Honda A; Bjornholm M; Takagi T; Naito Y
Article: DIABETES. 2022;71(4):624-636
Glutamine Regulates Skeletal Muscle Immunometabolism in Type 2 Diabetes
Dollet L; Kuefner M; Caria E; Rizo-Roca D; Pendergrast L; Abdelmoez AM; Karlsson HKR; Bjornholm M; Dalbram E; Treebak JT; Harada J; Naslund E; Ryden M; Zierath JR; Pillon NJ; Krook A
Article: MOLECULAR & CELLULAR PROTEOMICS. 2022;21(3):100207
Integrated Liver and Plasma Proteomics in Obese Mice Reveals Complex Metabolic Regulation
Stocks B; Gonzalez-Franquesa A; Borg ML; Bjornholm M; Niu L; Zierath JR; Deshmukh AS
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2021;321(5):C770-C778
Discovery of thymosin β4 as a human exerkine and growth factor
Gonzalez-Franquesa A; Stocks B; Borg ML; Kuefner M; Dalbram E; Nielsen TS; Agrawal A; Pankratova S; Chibalin AV; Karlsson HKR; Gheibi S; Bjornholm M; Jorgensen NR; Clemmensen C; Hostrup M; Treebak JT; Krook A; Zierath JR; Deshmukh AS
Article: SCIENCE ADVANCES. 2021;7(11):eabc2931
Lowering apolipoprotein CIII protects against high-fat diet-induced metabolic derangements
Valladolid-Acebes I; Avall K; Recio-Lopez P; Moruzzi N; Bryzgalova G; Bjornholm M; Krook A; Alonso EF; Ericsson M; Landfors F; Nilsson SK; Berggren P-O; Juntti-Berggren L
Article: FASEB JOURNAL. 2019;33(9):10551-10562
Secreted protein acidic and rich in cysteine (SPARC) improves glucose tolerance via AMP-activated protein kinase activation
Aoi W; Hirano N; Lassiter DG; Bjornholm M; Chibalin AV; Sakuma K; Tanimura Y; Mizushima K; Takagi T; Naito Y; Zierath JR; Krook A
Article: DIABETOLOGIA. 2019;62(2):233-237
Afternoon exercise is more efficacious than morning exercise at improving blood glucose levels in individuals with type 2 diabetes: a randomised crossover trial
Savikj M; Gabriel BM; Alm PS; Smith J; Caidahl K; Bjoernholm M; Fritz T; Krook A; Zierath JR; Wallberg-Henriksson H
Article: PROTEOMICS. 2018;18(5-6):e1700375
Proteomics Analysis of Skeletal Muscle from Leptin-Deficient ob/ob Mice Reveals Adaptive Remodeling of Metabolic Characteristics and Fiber Type Composition
Schonke M; Bjornholm M; Chibalin AV; Zierath JR; Deshmukh AS
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(9):E2048-E2057
The ZBED6-IGF2 axis has a major effect on growth of skeletal muscle and internal organs in placental mammals
Younis S; Schonke M; Massart J; Hjortebjerg R; Sundstrom E; Gustafson U; Bjornholm M; Krook A; Frystyk J; Zierath JR; Andersson L
Article: JOURNAL OF LIPID RESEARCH. 2018;59(2):273-282
Diacylglycerol kinase. deficiency alters inflammation markers in adipose tissue in response to a high-fat diet
Nascimento EBM; Manneras-Holm L; Chibalin AV; Bjornholm M; Zierath JR
Article: JOURNAL OF LIPID RESEARCH. 2017;58(12):2324-2333
DGKζ deficiency protects against peripheral insulin resistance and improves energy metabolism
Benziane B; Borg ML; Tom RZ; Riedl I; Massart J; Bjornholm M; Gilbert M; Chibalin AV; Zierath JR
Article: JOURNAL OF LIPID RESEARCH. 2017;58(5):907-915
Diacylglycerol kinase ε deficiency preserves glucose tolerance and modulates lipid metabolism in obese mice
Manneras-Holm L; Schonke M; Brozinick JT; Vetterli L; Bui H-H; Sanders P; Nascimento EBM; Bjornholm M; Chibalin AV; Zierath JR
Article: DIABETES. 2017;66(3):598-612
Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK
Kjobsted R; Munk-Hansen N; Birk JB; Foretz M; Viollet B; Bjornholm M; Zierath JR; Treebak JT; Wojtaszewski JFP
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2016;310(6):E461-E472
AMPKγ3 is dispensable for skeletal muscle hypertrophy induced by functional overload
Riedl I; Osler ME; Bjornholm M; Egan B; Nader GA; Chibalin AV; Zierath JR
Article: MOLECULAR METABOLISM. 2015;4(12):891-902
Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism
Correia JC; Massart J; de Boer JF; Porsmyr-Palmertz M; Martinez-Redondo V; Agudelo LZ; Sinha I; Meierhofer D; Ribeiro V; Bjornholm M; Sauer S; Dahlman-Wright K; Zierath JR; Groen AK; Ruas JL
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2015;309(7):E679-E690
Skeletal muscle AMP-activated protein kinase γ1^H151R overexpression enhances whole body energy homeostasis and insulin sensitivity
Schonke M; Myers MGJ; Zierath JR; Bjornholm M
Article: DIABETES. 2015;64(6):2042-2055
Prior AICAR Stimulation Increases Insulin Sensitivity in Mouse Skeletal Muscle in an AMPK-Dependent Manner
Kjobsted R; Treebak JT; Fentz J; Lantier L; Viollet B; Birk JB; Schjerling P; Bjornholm M; Zierath JR; Wojtaszewski JFP
Article: PHYSIOLOGICAL REPORTS. 2015;3(4):e12372
mRNA expression of diacylglycerol kinase isoforms in insulin-sensitive tissues: effects of obesity and insulin resistance.
Mannerås-Holm L; Kirchner H; Björnholm M; Chibalin AV; Zierath JR
Article: ELIFE. 2014;3:e03245
Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity
Guo T; Marmol P; Moliner A; Bjornholm M; Zhang C; Shokat KM; Ibanez CF
Article: DIABETES. 2014;63(5):1560-1571
Effects of AMPK Activation on Insulin Sensitivity and Metabolism in Leptin-Deficient ob/ob Mice
Tom RZ; Garcia-Roves PM; Sjogren RJO; Jiang LQ; Holmstrom MH; Deshmukh AS; Vieira E; Chibalin AV; Bjornholm M; Zierath JR
Article: METABOLISM-CLINICAL AND EXPERIMENTAL. 2013;62(9):1258-1267
Effect of leptin treatment on mitochondrial function in obese leptin-deficient ob/ob mice
Holmstrom MH; Tom RZ; Bjornholm M; Garcia-Roves PM; Zierath JR
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2012;303(4):E524-E533
The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism
Szekeres F; Chadt A; Tom RZ; Deshmukh AS; Chibalin AV; Bjornholm M; Al-Hasani H; Zierath JR
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(28):23451-23463
Activation of AMP-activated Protein Kinase Stimulates Na⁺,K⁺-ATPase Activity in Skeletal Muscle Cells
Benziane B; Bjornholm M; Pirkmajer S; Austin RL; Kotova O; Viollet B; Zierath JR; Chibalin AV
Article: ENDOCRINOLOGY. 2011;152(6):2237-2246
Increased Hepatic Insulin Sensitivity in Mice Lacking Inhibitory Leptin Receptor Signals
Tom RZ; Sjogren RJO; Vieira E; Glund S; Iglesias-Gutierrez E; Garcia-Roves PM; Myers MGJ; Bjornholm M
Article: ACTA PHYSIOLOGICA. 2010;199(2):221-230
Adenosine A₃ receptors regulate heart rate, motor activity and body temperature
Yang JN; Wang Y; Garcia-Roves PM; Bjornholm M; Fredholm BB
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2009;297(6):C1554-C1566
AMP-activated protein kinase activator A-769662 is an inhibitor of the Na⁺-K⁺-ATPase
Benziane B; Bjornholm M; Lantier L; Viollet B; Zierath JR; Chibalin AV
Article: CELL. 2008;132(3):375-386
Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance
Chibalin AV; Leng Y; Vieira E; Krook A; Bjoernholm M; Long YC; Kotova O; Zhong Z; Sakane F; Steiler T; Nylen C; Wang J; Laakso M; Topham MK; Gilbert M; Wallberg-Henriksson H; Zierath JR
Article: ENDOCRINOLOGY. 2007;148(11):5414-5423
Differential accessibility of circulating leptin to individual hypothalamic sites
Faouzi M; Leshan R; Bjoernholm M; Hennessey T; Jones J; Muenzberg H
Article: PLOS MEDICINE. 2007;4(5):e158-879
TXNIP regulates peripheral glucose metabolism in humans
Parikh H; Carlsson E; Chutkow WA; Johansson LE; Storgaard H; Poulsen P; Saxena R; Ladd C; Schulze PC; Mazzini MJ; Jensen CB; Krook A; Bjornholm M; Tornqvist H; Zierath JR; Ridderstrale M; Altshuler D; Lee RT; Vaag A; Groop LC; Mootha VK
Article: JOURNAL OF CLINICAL INVESTIGATION. 2007;117(5):1354-1360
Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function
Bjornholm M; Munzberg H; Leshan RL; Villanueva EC; Bates SH; Louis GW; Jones JC; Ishida-Takahashi R; Bjorbaek C; Myers MGJ
Article: JOURNAL OF NEUROSCIENCE. 2007;27(1):69-74
Appropriate inhibition of orexigenic hypothalamic arcuate nucleus neurons independently of leptin receptor/STAT3 signaling
Munzberg H; Jobst EE; Bates SH; Jones J; Villanueva E; Leshan R; Bjornholm M; Elmquist J; Sleeman M; Cowley MA; Myers MGJ
Article: DIABETES. 2005;54(5):1459-1467
Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes -: A randomized controlled study
Karlsson HKR; Hällsten K; Björnholm M; Tsuchida H; Chibalin AV; Virtanen KA; Heinonen OJ; Lönnqvist F; Nuutila P; Zierath JR
Article: MOLECULAR ENDOCRINOLOGY. 2005;19(4):925-938
Feedback inhibition of leptin receptor/Jak2 signaling via Tyr₁₁₃₈ of the leptin receptor and suppressor of cytokine signaling 3
Dunn SL; Björnholm M; Bates SH; Chen ZB; Seifert M; Myers MG
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2004;89(3):1301-1311
Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes
Storgaard H; Jensen CB; Björnholm MB; Song XM; Madsbad S; Zierath JR; Vaag AA
Article: JOURNAL OF PHYSIOLOGY-LONDON. 2003;550(1):305-315
Insulin signalling and resistance in patients with chronic heart failure
Kemppainen J; Tsuchida H; Stolen K; Karlsson H; Björnholm M; Heinonen OJ; Nuutila P; Krook A; Knuuti J; Zierath JR
Article: DIABETOLOGIA. 2002;45(12):1697-1702
Absence of functional insulin receptor substrate-3 (IRS-3) gene in humans
Björnholm M; He AR; Attersand A; Lake S; Liu SCH; Lienhard GE; Taylor S; Arner P; Zierath JR
Article: PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 2002;445(1):25-31
Gene expression of the p85α regulatory subunit of phosphatidylinositol 3-kinase in skeletal muscle from type 2 diabetic subjects
Tsuchida H; Björnholm M; Fernström M; Galuska D; Johansson P; Wallberg-Henriksson H; Zierath JR; Lake S; Krook A
Article: DIABETOLOGIA. 2002;45(8):1128-1135
Insulin signal transduction and glucose transport in human adipocytes:: effects of obesity and low calorie diet
Björnholm M; Al-Khalili L; Dicker A; Näslund E; Rössner S; Zierath JR; Arner P
Article: DIABETES. 2001;50(12):2770-2778
Insulin signal transduction in skeletal muscle from glucose-intolerant relatives with type 2 diabetes
Storgaard H; Song XM; Jensen CB; Madsbad S; Björnholm M; Vaag A; Zierath JR
Journal article: DIABETES RESEARCH AND CLINICAL PRACTICE. 2000;50:186
Insulin signal transduction and glucose transport in adipocytes from obese women: Effects of low calorie diet
Björnholm M; Al-Khalili L; Krook A; Rössner S; Zierath JR; Arner P
Article: DIABETES. 2000;49(4):647-654
Use of a novel impermeable biotinylated photolabeling reagent to assess insulin- and hypoxia-stimulated cell surface GLUT4 content in skeletal muscle from type 2 diabetic patients
Ryder JW; Yang J; Galuska D; Rincón J; Björnholm M; Krook A; Lund S; Pedersen O; Wallberg-Henriksson H; Zierath JR; Holman GD
Article: DIABETES. 2000;49(2):284-292
Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients
Krook A; Björnholm M; Galuska D; Jiang XJ; Fahlman R; Myers MG; Wallberg-Henriksson H; Zierath JR
Article: DIABETOLOGIA. 1999;42(Suppl 1):a1-a330
35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999.
Article: FASEB JOURNAL. 1998;12(15):1701-1712
Exercise-induced overexpression of key regulatory proteins involved in glucose uptake and metabolism in tetraplegic persons:: molecular mechanism for improved glucose homeostasis
Hjeltnes N; Galuska D; Björnholm M; Aksnes AK; Lannem A; Zierath JR; Wallberg-Henriksson H
Article: FASEB JOURNAL. 1998;12(13):1379-1389
Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle
Widegren U; Jiang XJ; Krook A; Chibalin AV; Björnholm M; Tally M; Roth RA; Henriksson J; Wallberg-Henriksson H; Zierath JR
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1998;275(2):E351-E358
Skeletal muscle insulin resistance after trauma: insulin signaling and glucose transport
Strommer L; Permert J; Arnelo U; Koehler C; Isaksson B; Larsson J; Lundkvist I; Bjornholm M; Kawano Y; Wallberg-Henriksson H; Zierath JR
Article: DIABETES. 1997;46(3):524-527
Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation
Bjornholm M; Kawano Y; Lehtihet M; Zierath JR
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Alla övriga publikationer

Editorial comment: ACTA PHYSIOLOGICA. 2014;211(2):257-259
Chronic glucocorticoid treatment increases de novo lipogenesis in visceral adipose tissue
Vienberg SG; Bjoernholm M
Published conference paper: OBESITY. 2006;14 Suppl 5:208S-212S
Leptin receptor signaling and action in the central nervous system.
Leshan RL; Björnholm M; Münzberg H; Myers MG
Published conference paper: BIOCHEMICAL SOCIETY TRANSACTIONS. 2005;33(Pt 2):354-357
Insulin signal transduction in human skeletal muscle:: identifying the defects in type II diabetes
Björnholm M; Zierath JR
Review: CELLULAR AND MOLECULAR LIFE SCIENCES. 2005;62(6):642-652
Leptin receptor action and mechanisms of leptin resistance
Münzberg H; Björnholm M; Bates SH; Myers MG
Thesis / dissertation: 2002
Molecular mechanisms of insulin action in human skeletal muscle and adipose tissue : implications for diabetes and obesity
Björnholm, Marie

Anställningar

Senior Forskningsspecialist, Molekylär medicin och kirurgi, Karolinska Institutet, 2022-

Examina och utbildning

MEDICINE DOKTORSEXAMEN, Institutionen för fysiologi och farmakologi, Karolinska Institutet, 2002

Artiklar

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Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI