Marie Arsenian-Henriksson

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Marie Arsenian Henriksson blev professor i molekylär tumörbiologi vid Karolinska Institutet 2010. Sedan mars 2023 är hon också KI:s vicerektor för forskning. Hon har tidigare varit prefekt för institutionen för mikrobiologi, tumör- och cellbiologi (2006-2016), lärarrepresentant i konsistoriet (2019-2021) och är även ledamot i KI:s rekryteringsnämnd sedan 2021.

Forskningsbeskrivning

Marie Arsenian Henrikssons forskning fokuserar på de så kallade MYC-generna, som är aktiverade i minst en tredjedel av alla cancerformer, inklusive lymfom, bröstcancer och neuroblastom. Neuroblastom är den barncancer som har störst dödlighet näst efter leukemi, och där amplifiering av MYCN-genen (N står för neuro) har samband med en sämre prognos.

Forskningen kring MYC-generna syftar till ökad kunskap om hur dessa gener fungerar under normala förhållanden respektive bidrar till utveckling av tumörsjukdomar. Kunskap som är viktigt för utveckling av nya, skräddarsydda cancerbehandlingar.

Artiklar

Article: NEURO-ONCOLOGY. 2024;:noae152

Defining Neuroblastoma: from origin to precision medicine.

Sainero-Alcolado L; Bexelius TS; Santopolo G; Yuan Y; Liaño-Pons J; Arsenian-Henriksson M
Article: SCIENCE ADVANCES. 2024;10(25):eado1583

MOXD1 is a lineage-specific gene and a tumor suppressor in neuroblastoma

Fredlund E; Andersson S; Hilgert E; Monferrer E; alvarez-Hernan G; Karakaya S; Loontiens S; Bek JW; Gregor T; Lecomte E; Magnusson E; Miltenyte E; Cabirol M; Kyknas M; Engstroem N; Henriksson MA; Hammarlund E; Rosenblum JS; Noguera R; Speleman F; van Nes J; Mohlin S
Article: CANCER RESEARCH COMMUNICATIONS. 2024;4(3):691-705

Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation.

Carroll C; Manaprasertsak A; Boffelli Castro A; van den Bos H; Spierings DCJ; Wardenaar R; Bukkuri A; Engström N; Baratchart E; Yang M; Biloglav A; Cornwallis CK; Johansson B; Hagerling C; Arsenian-Henriksson M; Paulsson K; Amend SR; Mohlin S; Foijer F; McIntyre A; Pienta KJ; Hammarlund EU
Article: NATURE COMMUNICATIONS. 2024;15(1):1865

A druggable conformational switch in the c-MYC transactivation domain

Lama D; Vosselman T; Sahin C; Liano-Pons J; Cerrato CP; Nilsson L; Teilum K; Lane DP; Landreh M; Arsenian Henriksson M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2024;121(7):e2310479121

Targeting MYC induces lipid droplet accumulation by upregulation of HILPDA in clear cell renal cell carcinoma

Sainero-Alcolado L; Garde-Lapido E; Snaebjornsson MT; Schoch S; Stevens I; Ruiz-Perez MV; Dyrager C; Pelechano V; Axelson H; Schulze A; Arsenian-Henriksson M
Article: SCIENCE ADVANCES. 2023;9(41):eadg5109

Coinhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills pancreatic cancer via readthrough transcription

Cameron DP; Grosser J; Ladigan S; Kuzin V; Iliopoulou E; Wiegard A; Benredjem H; Jackson K; Liffers ST; Lueong S; Cheung PF; Vangala D; Pohl M; Viebahn R; Teschendorf C; Wolters H; Usta S; Geng K; Kutter C; Arsenian-Henriksson M; Siveke JT; Tannapfel A; Schmiegel W; Hahn SA; Baranello L
Article: CANCERS. 2023;15(18):4599

Target Genes of c-MYC and MYCN with Prognostic Power in Neuroblastoma Exhibit Different Expressions during Sympathoadrenal Development

Yuan Y; Alzrigat M; Rodriguez-Garcia A; Wang X; Bexelius TS; Johnsen JI; Arsenian-Henriksson M; Liano-Pons J; Bedoya-Reina OC
Article: NANOMEDICINE. 2023;18(18):1161-1173

Organ uptake, toxicity and skin clearance of ruthenium contrast agents monitored in vivo by x-ray fluorescence

Vogt C; Saladino GM; Shaker K; Arsenian-Henriksson M; Hertz HM; Toprak MS; Brodin BA
Article: ANALYTICAL CHEMISTRY. 2023;95(29):10869-10872

Monitoring Disassembly and Cargo Release of Phase-Separated Peptide Coacervates with Native Mass Spectrometry

Cerrato CPP; Leppert A; Sun Y; Lane DPP; Arsenian-Henriksson M; Miserez A; Landreh M
Article: PNAS NEXUS. 2023;2(2):pgac303

A "grappling hook" interaction connects self-assembly and chaperone activity of Nucleophosmin 1

Saluri M; Leppert A; Gese GV; Sahin C; Lama D; Kaldmae M; Chen G; Elofsson A; Allison TM; Arsenian-Henriksson M; Johansson J; Lane DP; Hallberg BM; Landreh M
Article: NANOSCALE. 2023;15(5):2214-2222

XFCT-MRI hybrid multimodal contrast agents for complementary imaging

Saladino GM; Vogt C; Brodin B; Shaker K; Kilic NI; Andersson K; Arsenian-Henriksson M; Toprak MS; Hertz HM
Article: SCIENTIFIC REPORTS. 2023;13(1):1273

Metabolic rewiring in MYC-driven medulloblastoma by BET-bromodomain inhibition

Graziani V; Garcia AR; Alcolado LS; Le Guennec A; Henriksson MA; Conte MRR
Article: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 2022;41(1):226

Expression and activation of nuclear hormone receptors result in neuronal differentiation and favorable prognosis in neuroblastoma

Sainero-Alcolado L; Mushtaq M; Liano-Pons J; Rodriguez-Garcia A; Yuan Y; Liu T; Ruiz-Perez MV; Schlisio S; Bedoya-Reina O; Arsenian-Henriksson M
Article: NATURE METABOLISM. 2022;4(6):739-758

Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel-Lindau syndrome

Li S; Li W; Yuan J; Bullova P; Wu J; Zhang X; Liu Y; Plescher M; Rodriguez J; Bedoya-Reina OC; Jannig PR; Valente-Silva P; Yu M; Henriksson MA; Zubarev RA; Smed-Sorensen A; Suzuki CK; Ruas JL; Holmberg J; Larsson C; Christofer Juhlin C; von Kriegsheim A; Cao Y; Schlisio S
Article: STRUCTURE. 2022;30(5):733-742.e7

A "spindle and thread"mechanism unblocks p53 translation N-terminal disorder

Kaldmae M; Vosselman T; Zhong X; Lama D; Chen G; Saluri M; Kronqvist N; Siau JW; Ng AS; Ghadessy FJ; Sabatier P; Vojtesek B; Sarr M; Sahin C; Osterlund N; Ilag LL; Vaananen VA; Sedimbi S; Arsenian-Henriksson M; Zubarev RA; Nilsson L; Koeck PJB; Rising A; Abelein A; Fritz N; Johansson J; Lane DP; Landreh M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(6):e2102358119

Epigenetic state determines inflammatory sensing in neuroblastoma

Wolpaw AJ; Grossmann LD; Dessau JL; Dong MM; Aaron BJ; Brafford PA; Volgina D; Pascual-Pasto G; Rodriguez-Garcia A; Uzun Y; Arsenian-Henriksson M; Powell DJJ; Bosse KR; Kossenkov A; Tan K; Hogarty MD; Maris JM; Dang CV
Article: CHEMPHOTOCHEM. 2021;5(7):632-643

Photophysical Characteristics of Polarity-Sensitive and Lipid Droplet-Specific Phenylbenzothiadiazoles

Colas K; Doloczki S; Kesidou A; Sainero-Alcolado L; Rodriguez-Garcia A; Arsenian-Henriksson M; Dyrager C
Article: ISCIENCE. 2021;24(5):102494

DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance

Zhang J; Teran G; Popa M; Madapura H; Ladds MJGW; Lianoudaki D; Grunler J; Arsenian-Henriksson M; McCormack E; Rottenberg ME; Catrina S-B; Lain S; Darekar S
Article: BMC BIOLOGY. 2021;19(1):57

Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling

Naia L; Pinho CM; Dentoni G; Liu J; Leal NS; Ferreira DMS; Schreiner B; Filadi R; Fao L; Connolly NMC; Forsell P; Nordvall G; Shimozawa M; Greotti E; Basso E; Theurey P; Gioran A; Joselin A; Arsenian-Henriksson M; Nilsson P; Rego AC; Ruas JL; Park D; Bano D; Pizzo P; Prehn JHM; Ankarcrona M
Article: ISCIENCE. 2021;24(2):102128

Inhibition of fatty acid synthesis induces differentiation and reduces tumor burden in childhood neuroblastoma

Victoria Ruiz-Perez M; Sainero-Alcolado L; Oliynyk G; Matuschek I; Balboni N; Ubhayasekera SJKA; Snaebjornsson MT; Makowski K; Aaltonen K; Bexell D; Serra D; Nilsson R; Bergquist J; Schulze A; Arsenian-Henriksson M
Article: COMMUNICATIONS PHYSICS. 2021;4(1):259

Phase-contrast X-ray tomography resolves the terminal bronchioles in free-breathing mice

Shaker K; Haggmark I; Reichmann J; Arsenian-Henriksson M; Hertz HM
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(50):32005-32016

Targeting a scavenger receptor on tumor-associated macrophages activates tumor cell killing by natural killer cells

Eisinger S; Sarhan D; Boura VF; Ibarlucea-Benitez I; Tyystjarvi S; Oliynyk G; Arsenian-Henriksson M; Lane D; Wikstrom SL; Kiessling R; Virgilio T; Gonzalez SF; Kaczynska D; Kanatani S; Daskalaki E; Wheelock CE; Sedimbi S; Chambers BJ; Ravetch JV; Karlsson MCI
Article: IEEE TRANSACTIONS ON MEDICAL IMAGING. 2020;39(12):3910-3919

Longitudinal In-Vivo X-Ray Fluorescence Computed Tomography With Molybdenum Nanoparticles

Shaker K; Vogt C; Katsu-Jimenez Y; Kuiper RV; Andersson K; Li Y; Larsson JC; Rodriguez-Garcia A; Toprak MS; Arsenian-Henriksson M; Hertz HM
Article: FASEB JOURNAL. 2020;34(8):10818-10834

The chromatin-remodeling complexes B-WICH and NuRD regulate ribosomal transcription in response to glucose

Rolicka A; Guo Y; Ganez Zapater A; Tariq K; Quin J; Vintermist A; Sadeghifar F; Arsenian-Henriksson M; Ostlund Farrants A-K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(27):15673-15683

Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2

Mushtaq M; Kovalevska L; Darekar S; Abramsson A; Zetterberg H; Kashuba V; Klein G; Arsenian-Henriksson M; Kashuba E
Article: CELL DEATH & DISEASE. 2020;11(1):52

p53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids

Navarro AM; Pronk RJ; van der Geest AT; Oliynyk G; Nordgren A; Arsenian-Henriksson M; Falk A; Wilhelm M
Article: NATURE COMMUNICATIONS. 2020;11(1):71

Integrative discovery of treatments for high-risk neuroblastoma

Almstedt E; Elgendy R; Hekmati N; Rosen E; Warn C; Olsen TK; Dyberg C; Doroszko M; Larsson I; Sundstrom A; Henriksson MA; Pahlman S; Bexell D; Vanlandewijck M; Kogner P; Jornsten R; Krona C; Nelander S
Article: ISCIENCE. 2019;21:188-204

MYCN-enhanced Oxidative and Glycolytic Metabolism Reveals Vulnerabilities for Targeting Neuroblastoma

Oliynyk G; Ruiz-Perez MV; Sainero-Alcolado L; Dzieran J; Zirath H; Gallart-Ayala H; Wheelock CE; Johansson HJ; Nilsson R; Lehtio J; Arsenian-Henriksson M
Article: IMMUNITY. 2019;51(1):169-184.e5

Single-Cell RNA Sequencing of the T Helper Cell Response to House Dust Mites Defines a Distinct Gene Expression Signature in Airway Th2 Cells

Tibbitt CA; Stark JM; Martens L; Ma J; Mold JE; Deswarte K; Oliynyk G; Feng X; Lambrecht BN; De Bleser P; Nylen S; Hammad H; Henriksson MA; Saeys Y; Coquet JM
Article: PHYSICS IN MEDICINE AND BIOLOGY. 2018;63(16):164001

High-spatial-resolution x-ray fluorescence tomography with spectrally matched nanoparticles

Larsson JC; Vogt C; Vagberg W; Toprak MS; Dzieran J; Arsenian-Henriksson M; Hertz HM
Article: NATURE COMMUNICATIONS. 2018;9(1):1107

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

Ladds MJGW; van Leeuwen IMM; Drummond CJ; Chu S; Healy AR; Popova G; Fernandez AP; Mollick T; Darekar S; Sedimbi SK; Nekulova M; Sachweh MCC; Campbell J; Higgins M; Tuck C; Popa M; Safont MM; Gelebart P; Fandalyuk Z; Thompson AM; Svensson R; Gustavsson A-L; Johansson L; Farnegardh K; Yngve U; Saleh A; Haraldsson M; D'Hollander ACA; Franco M; Zhao Y; Hakansson M; Walse B; Larsson K; Peat EM; Pelechano V; Lunec J; Vojtesek B; Carmena M; Earnshaw WC; McCarthy AR; Westwood NJ; Arsenian-Henriksson M; Lane DP; Bhatia R; McCormack E; Lain S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(6):E1229-E1238

MYCN-amplified neuroblastoma maintains an aggressive and undifferentiated phenotype by deregulation of estrogen and NGF signaling

Dzieran J; Garcia AR; Westermark UK; Henley AB; Sanchez EE; Trager C; Johansson HJ; Lehtio J; Arsenian-Henriksson M
Article: SCIENTIFIC REPORTS. 2017;7(1):10274

Neuroblastoma patient-derived xenograft cells cultured in stem-cell promoting medium retain tumorigenic and metastatic capacities but differentiate in serum

Persson CU; von Stedingk K; Bexell D; Merselius M; Braekeveldt N; Gisselsson D; Arsenian-Henriksson M; Pahlman S; Wigerup C
Article: GENES & DEVELOPMENT. 2017;31(10):1036-1053

Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA

Fell SM; Li S; Wallis K; Kock A; Surova O; Rraklli V; Hoefig CS; Li W; Mittag J; Henriksson MA; Kenchappa RS; Holmberg J; Kogner P; Schlisio S
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2016;136(12):2485-2494

MicroRNA-203 Inversely Correlates with Differentiation Grade, Targets c-MYC, and Functions as a Tumor Suppressor in cSCC

Lohcharoenkal W; Harada M; Loven J; Meisgen F; Landen NX; Zhang L; Lapins J; Das Mahapatra K; Shi H; Nissinen L; Kahari V-M; Stahle M; Sonkoly E; Grander D; Arsenian-Henriksson M; Pivarcsi A
Article: JOURNAL OF NEUROSCIENCE. 2016;36(40):10425-10439

Proliferation and Survival of Embryonic Sympathetic Neuroblasts by MYCN and Activated ALK Signaling

Kramer M; Ribeiro D; Arsenian-Henriksson M; Deller T; Rohrer H
Article: CELL REPORTS. 2016;16(4):979-993

Regulation of Nuclear Hormone Receptors by MYCN-Driven miRNAs Impacts Neural Differentiation and Survival in Neuroblastoma Patients

Ribeiro D; Klarqvist MDR; Westermark UK; Oliynyk G; Dzieran J; Kock A; Banares CS; Hertwig F; Johnsen JI; Fischer M; Kogner P; Loven J; Henriksson MA
Article: ONCOTARGET. 2015;6(32):32380-32395

Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids

Wang H; Teriete P; Hu A; Raveendra-Panickar D; Pendelton K; Lazo JS; Eiseman J; Holien T; Misund K; Oliynyk G; Arsenian-Henriksson M; Cosford NDP; Sundan A; Prochownik EV
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(26):8070-8075

COX/mPGES-1/PGE₂ pathway depicts an inflammatory-dependent high-risk neuroblastoma subset

Larsson K; Kock A; Idborg H; Henriksson MA; Martinsson T; Johnsen JI; Korotkova M; Kogner P; Jakobsson P-J
Article: VIROLOGY. 2015;476:271-288

Acetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30^II accessory protein and the induction of oncogenic cellular transformation by p30^II/c-MYC

Romeo MM; Ko B; Kim J; Brady R; Heatley HC; He J; Harrod CK; Barnett B; Ratner L; Lairmore MD; Martinez E; Luescher B; Robson CN; Henriksson M; Harrod R
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(1):220-225

TAp73 suppresses tumor angiogenesis through repression of proangiogenic cytokines and HIF-1α activity

Stantic M; Sakil HAM; Zirath H; Fang T; Sanz G; Fernandez-Woodbridge A; Marin A; Susanto E; Mak TW; Henriksson MA; Wilhelm MT
Article: PHYSICS IN MEDICINE AND BIOLOGY. 2014;59(11):2801-2811

X-ray phase contrast with injected gas for tumor microangiography

Lundstrom U; Westermark UK; Larsson DH; Burvall A; Henriksson MA; Hertz HM
Article: EMBO REPORTS. 2014;15(4):383-391

MYC proteins promote neuronal differentiation by controlling the mode of progenitor cell division

Zinin N; Adameyko I; Wilhelm M; Fritz N; Uhlen P; Ernfors P; Henriksson MA
Article: PLOS ONE. 2014;9(5):e97285

Targeting of the MYCN Protein with Small Molecule c-MYC Inhibitors

Muller I; Larsson K; Frenzel A; Oliynyk G; Zirath H; Prochownik EV; Westwood NJ; Henriksson MA
Article: EXPERIMENTAL CELL RESEARCH. 2013;319(20):3160-3169

Chromatin dynamics at the hTERT promoter during transcriptional activation and repression by c-Myc and Mnt in Xenopus leavis oocytes

Wahlstrom T; Belikov S; Henriksson MA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(25):10258-10263

MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells

Zirath H; Frenzel A; Oliynyk G; Segerstrom L; Westermark UK; Larsson K; Persson MM; Hultenby K; Lehtio J; Einvik C; Pahlman S; Kogner P; Jakobsson P-J; Henriksson MA
Article: MEDICAL PHYSICS. 2013;40(2):021909

First application of liquid-metal-jet sources for small-animal imaging: High-resolution CT and phase-contrast tumor demarcation

Larsson DH; Lundstrom U; Westermark UK; Henriksson MA; Burvall A; Hertz HM
Article: PHYSICS IN MEDICINE AND BIOLOGY. 2012;57(22):7431-7441

X-ray phase-contrast CO₂ angiography for sub-10 μm vessel imaging

Lundstrom U; Larsson DH; Burvall A; Scott L; Westermark UK; Wilhelm M; Henriksson MA; Hertz HM
Article: ONCOGENESIS. 2012;1(3):e3

MicroRNA-203 functions as a tumor suppressor in basal cell carcinoma

Sonkoly E; Loven J; Xu N; Meisgen F; Wei T; Brodin P; Jaks V; Kasper M; Shimokawa T; Harada M; Heilborn J; Hedblad M-A; Hippe A; Grander D; Homey B; Zaphiropoulos PG; Arsenian-Henriksson M; Stahle M; Pivarcsi A
Article: PLOS ONE. 2011;6(11):e27988

Identification of Cytotoxic Drugs That Selectively Target Tumor Cells with MYC Overexpression

Frenzel A; Zirath H; Vita M; Albihn A; Henriksson MA
Article: GENES AND CANCER. 2010;1(6):660-667

Targeting MYC-Regulated miRNAs to Combat Cancer.

Frenzel A; Lovén J; Henriksson MA
Article: GENES & DEVELOPMENT. 2010;24(6):549-560

Isoform-specific p73 knockout mice reveal a novel role for ΔNp73 in the DNA damage response pathway

Wilhelm MT; Rufini A; Wetzel MK; Tsuchihara K; Inoue S; Tomasini R; Itie-Youten A; Wakeham A; Arsenian-Henriksson M; Melino G; Kaplan DR; Miller FD; Mak TW
Article: ONCOGENE. 2010;29(4):503-515

Chromosomal rearrangements after ex vivo Epstein-Barr virus (EBV) infection of human B cells

Lacoste S; Wiechec E; Silva AGDS; Guffei A; Williams G; Lowbeer M; Benedek K; Henriksson M; Klein G; Mai S
Article: PLOS ONE. 2010;5(1):e8924

Myc Is Required for Activation of the ATM-Dependent Checkpoints in Response to DNA Damage

Guerra L; Albihn A; Tronnersjo S; Yan Q; Guidi R; Stenerlow B; Sterzenbach T; Josenhans C; Fox JG; Schauer DB; Thelestam M; Larsson L-G; Henriksson M; Frisan T
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(4):1553-1558

MYCN-regulated microRNAs repress estrogen receptor-α (ESR1) expression and neuronal differentiation in human neuroblastoma

Loven J; Zinin N; Wahlstrom T; Muller I; Brodin P; Fredlund E; Ribacke U; Pivarcsi A; Pahlman S; Henriksson M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(1):58-63

Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation

Hydbring P; Bahram F; Su Y; Tronnersjo S; Hogstrand K; von der Lehr N; Sharifi HR; Lilischkis R; Hein N; Wu S; Vervoorts J; Henriksson M; Grandien A; Luscher B; Larsson L-G
Article: EXPERIMENTAL CELL RESEARCH. 2009;315(17):2941-2952

DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

Lerner M; Harada M; Loven J; Castro J; Davis Z; Oscier D; Henriksson M; Sangfelt O; Grander D; Corcoran MM
Article: BIOCHEMISTRY-MOSCOW. 2008;73(11):1260-1268

Identification of recognition sites for Myc/Max/Mxd network proteins by a whole human chromosome 19 selection strategy

Akopov SB; Chernov IP; Wahlstrom T; Kostina MB; Klein G; Henriksson M; Nikolaev LG
Article: ONCOGENE. 2008;27(20):2910-2922

Inhibitors of mammalian target of rapamycin downregulate MYCN protein expression and inhibit neuroblastoma growth in vitro and in vivo

Johnsen JI; Segerstrom L; Orrego A; Elfman L; Henriksson M; Kagedal B; Eksborg S; Sveinbjornsson B; Kogner P
Article: LEUKEMIA RESEARCH. 2008;32(2):297-307

Role of Myc in differentiation and apoptosis in HL60 cells after exposure to arsenic trioxide or all-trans retinoic acid

Jiang G; Albihn A; Tang T; Tian Z; Henriksson M
Article: INTERNATIONAL JOURNAL OF CANCER. 2007;121(8):1821-1829

Camptothecin-induced apoptosis is enhanced by Myc and involves PKCdelta signaling

Albihn A; Mo H; Yang Y; Henriksson M
Article: BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION. 2007;35(3):187-192

Open-ended assignments and student responsibility

Brauner A; Carey J; Henriksson M; Sunnerhagen M; Ehrenborg E
Article: CELL CYCLE. 2006;5(19):2191-2194

Myc overexpression enhances apoptosis induced by small molecules

Mo H; Vita M; Crespin M; Henriksson M
Article: JOURNAL OF CELLULAR BIOCHEMISTRY. 2006;98(6):1597-1614

c-Myc-dependent etoposide-induced apoptosis involves activation of Bax and caspases, and PKCdelta signaling

Albihn A; Loven J; Ohlsson J; Osorio LM; Henriksson M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(16):6344-6349

Identification of small molecules that induce apoptosis in a Myc-dependent manner and inhibit Myc-driven transformation

Mo H; Henriksson M
Article: ONCOGENE. 2005;24(56):8326-8337

Mnt transcriptional repressor is functionally regulated during cell cycle progression

Popov N; Wahlström T; Hurlin PJ; Henriksson M
Article: CANCER RESEARCH. 2005;65(4):1361-1368

Mitotic infidelity and centrosome duplication errors in cells overexpressing tripeptidyl-peptidase II

Stavropoulou V; Xie JJ; Henriksson M; Tomkinson B; Imreh S; Masucci MG
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2004;323(3):750-759

Biophysical properties of regions flanking the bHLH-Zip motif in the p22 Max protein

Pursglove SE; Fladvad M; Bellanda M; Moshref A; Henriksson M; Carey J; Sunnerhagen M
Article: JOURNAL OF CELLULAR BIOCHEMISTRY. 2004;92(6):1282-1295

Expression and DNA-binding activity of MYCN/max and Mnt/max during induced differentiation of human neuroblastoma cells

Smith AG; Popov N; Imreh M; Axelson H; Henriksson M
Article: CELL DEATH AND DIFFERENTIATION. 2003;10(12):1320-1328

The herpes simplex virus-1 Us3 protein kinase blocks CD8T cell lysis by preventing the cleavage of Bid by granzyme B

Cartier A; Broberg E; Komai T; Henriksson M; Masucci MG
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(13):11094-11099

The Mad and Myc basic domains are functionally equivalent

Nikiforov MA; Popov N; Kotenko I; Henriksson M; Cole MD
Article: EXPERIMENTAL CELL RESEARCH. 2002;274(1):25-34

The histone deacetylase inhibitor trichostatin a derepresses the telomerase reverse transcriptase (hTERT) gene in human cells

Hou M; Wang XB; Popov N; Zhang AJ; Zhao XY; Zhou R; Zetterberg A; Björkholm M; Henriksson M; Gruber A; Xu DW
Article: ONCOGENE. 2002;21(3):447-459

Repression of in vivo growth of Myc/Ras transformed tumor cells by Mad1

Cerni C; Skrzypek B; Popov N; Sasgary S; Schmidt G; Larsson LG; Lüscher B; Henriksson M
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002;290(1):11-15

c-myc suppression in Burkitt's lymphoma cells

Simonsson T; Henriksson M
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2001;19(4):773-777

Differential expression of class IHDACs:: Roles of cell density and cell cycle

Dangond F; Henriksson M; Zardo G; Caiafa P; Ekström TJ; Gray SG
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(11):6407-6411

Horizontal transfer of oncogenes by uptake of apoptotic bodies

Bergsmedh A; Szeles A; Henriksson M; Bratt A; Folkman MJ; Spetz AL; Holmgren L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(7):3826-3831

Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells

Xu DW; Popov N; Hou M; Wang Q; Björkholm M; Gruber A; Menkel AR; Henriksson M
Article: APOPTOSIS. 2001;6(1-2):133-137

Inactivation of Myc-induced p53-dependent apoptosis in human tumors

Henriksson M; Selivanova G; Lindström M; Wiman KG
Article: CANCER RESEARCH. 2000;60(22):6230-6235

Frequent amplification of the Telomerase Reverse Transcriptase gene in human tumors

Zhang AJ; Zheng CY; Lindvall C; Hou M; Ekedahl J; Lewensohn R; Yan ZQ; Yang XY; Henriksson M; Blennow E; Nordenskjöld M; Zetterberg A; Björkholm M; Gruber A; Xu DW
Article: EXPERIMENTAL CELL RESEARCH. 2000;260(1):61-72

Inhibition of cell growth and apoptosis by inducible expression of the transcriptional repressor Mad1

Bejarano MT; Albihn A; Cornvik T; Brijker SO; Asker C; Osorio LM; Henriksson M
Article: ONCOGENE. 1999;18(41):5620-5630

Interaction of the fork head domain transcription factor MPP2 with the human papilloma virus 16 E7 protein:: enhancement of transformation and transactivation

Lüscher-Firzlaff JM; Westendorf JM; Zwicker J; Burkhardt H; Henriksson M; Müller R; Pirollet F; Lüscher B
Article: EUROPEAN JOURNAL OF CANCER. 1995;31A(12):2099-2104

The amino-terminal phosphorylation sites of C-MYC are frequently mutated in Burkitt's lymphoma lines but not in mouse plasmacytomas and rat immunocytomas

Axelson H; Henriksson M; Wang Y; Magnusson KP; Klein G
Article: ONCOGENE. 1995;11(3):587-596

DIFFERENTIAL-EFFECTS BY MAD AND MAX ON TRANSFORMATION BY CELLULAR AND VIRAL ONCOPROTEINS

CERNI C; BOUSSET K; SEELOS C; BURKHARDT H; HENRIKSSON M; LUSCHER B
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Corrigendum: NATURE COMMUNICATIONS. 2023;14(1):5019

Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage (vol 14, 5019, 2023)

Ladds MJGW; van Leeuwen IMM; Drummond CJ; Chu S; Healy AR; Popova G; Fernandez AP; Mollick T; Darekar S; Sedimbi SK; Nekulova M; Sachweh MCC; Campbell J; Higgins M; Tuck C; Popa M; Safont MM; Gelebart P; Fandalyuk Z; Thompson AM; Svensson R; Gustavsson A-L; Johansson L; Faernegardh K; Yngve U; Saleh A; Haraldsson M; D'Hollander ACA; Franco M; Zhao Y; Hakansson M; Walse B; Larsson K; Peat EM; Pelechano V; Lunec J; Vojtesek B; Carmena M; Earnshaw WC; McCarthy AR; Westwood NJ; Arsenian-Henriksson M; Lane DP; Bhatia R; McCormack E; Lain S
Corrigendum: NATURE METABOLISM. 2022;4(10):1421

Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel-Lindau syndrome (June, 10.1038/s42255-022-00593-x, 2022)

Li S; Li W; Yuan J; Bullova P; Wu J; Zhang X; Liu Y; Plescher M; Rodriguez J; Bedoya-Reina OC; Jannig PR; Valente-Silva P; Yu M; Henriksson MA; Zubarev RA; Smed-Sorensen A; Suzuki CK; Ruas JL; Holmberg J; Larsson C; Christofer Juhlin C; von Kriegsheim A; Cao Y; Schlisio S
Review: CELL DEATH AND DIFFERENTIATION. 2022;29(7):1304-1317

Targeting mitochondrial metabolism for precision medicine in cancer

Sainero-Alcolado L; Liano-Pons J; Ruiz-Perez MV; Arsenian-Henriksson M
Review: CANCERS. 2021;13(18):4682

The Multiple Faces of MNT and Its Role as a MYC Modulator

Liano-Pons J; Arsenian-Henriksson M; Leon J
Editorial comment: CANCER RESEARCH. 2019;79(15):3818-3819

Serine-Glycine-One-Carbon Metabolism: The Hidden Achilles Heel of MYCN-Amplified Neuroblastoma?

Garcia AR; Arsenian-Henriksson M
Corrigendum: NATURE COMMUNICATIONS. 2018;9(1):2071

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

Ladds MJGW; van Leeuwen IMM; Drummond CJ; Chu S; Healy AR; Popova G; Fernandez AP; Mollick T; Darekar S; Sedimbi SK; Nekulova M; Sachweh MCC; Campbell J; Higgins M; Tuck C; Popa M; Safont MM; Gelebart P; Fandalyuk Z; Thompson AM; Svensson R; Gustavsson A-L; Johansson L; Farnegardh K; Yngve U; Saleh A; Haraldsson M; D'Hollander ACA; Franco M; Zhao Y; Hakansson M; Walse B; Larsson K; Peat EM; Pelechano V; Lunec J; Vojtesek B; Carmena M; Earnshaw WC; McCarthy AR; Westwood NJ; Arsenian-Henriksson M; Lane DP; Bhatia R; McCormack E; Lain S
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2018;19(5):E1532-1532

Fibroblasts in the Tumor Microenvironment: Shield or Spear?

Alkasalias T; Moyano-Galceran L; Arsenian-Henriksson M; Lehti K
Review: GENES. 2017;8(4):E113-113

The MYCN Protein in Health and Disease

Ruiz-Perez MV; Henley AB; Arsenian-Henriksson M
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2015;1849(5):563-569

Impact of MYC in regulation of tumor cell metabolism

Wahlstrom T; Henriksson MA
Review: SEMINARS IN CANCER BIOLOGY. 2011;21(4):256-266

The MYCN oncogene and differentiation in neuroblastoma

Westermark UK; Wilhelm M; Frenzel A; Henriksson MA
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2011;21(4):215-216

Neuroblastoma research progress - A 2011 perspective

Henriksson MA; Pahlman S
Review: EXPERIMENTAL CELL RESEARCH. 2010;316(8):1429-1437

The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy

Larsson L-G; Henriksson MA
Review: MECHANISMS AND THERAPY OF LIVER CANCER. 2010;107:163-224

MYC in Oncogenesis and as a Target for Cancer Therapies

Albihn A; Johnsen JI; Henriksson MA
Review: APOPTOSIS. 2009;14(4):424-438

Embryonal neural tumours and cell death

Johnsen JI; Kogner P; Albihn A; Henriksson MA
Review: MECHANISMS AND THERAPY OF LIVER CANCER. 2007;97:61-80

Mnt takes control as key regulator of the Myc/Max/Mxd network

Wahlstrom T; Henriksson M
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2006;16(4):241

25 years of the c-Myc oncogene

Cole MD; Henriksson M
Review: SEMINARS IN CANCER BIOLOGY. 2006;16(4):318-330

The Myc oncoprotein as a therapeutic target for human cancer

Vita M; Henriksson M
Published conference paper: CANCER RESEARCH. 2003;63(8):1743-1747

Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling:: Activation of the Epiregulin gene

Lindvall C; Hou M; Komurasaki T; Zheng CY; Henriksson M; Sedivy JM; Björkholm M; Teh BT; Nordenskjöld M; Xu DW
Review: NANOPARTICLES FOR RATIONAL VACCINE DESIGN. 1997;224:123-130

Regulation of cell growth by the Myc-Max-Mad network: Role of Mad proteins and YY1

Austen M; Cerni C; Henriksson M; Hilfenhaus S; LuscherFirzlaff JM; Menkel A; Seelos C; Sommer A; Luscher B
Review: MECHANISMS AND THERAPY OF LIVER CANCER. 1996;68:109-182

Proteins of the Myc network: Essential regulators of cell growth and differentiation

Henriksson M; Luscher B

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Professor, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2010-

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