Marianne Farnebo

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: MOLECULAR ONCOLOGY. 2023;17(10):2029-2040
Low levels of WRAP53 predict decreased efficacy of radiotherapy and are prognostic for local recurrence and death from breast cancer: a long-term follow-up of the SweBCG91RT randomized trial
Egelberg M; De Marchi T; Pekar G; Tran L; Bendahl P-O; Tullberg AS; Holmberg E; Karlsson P; Farnebo M; Killander F; Nimeus E
Article: SCIENCE ADVANCES. 2023;9(30):eadg1805
Control of protein synthesis through mRNA pseudouridylation by dyskerin
Pederiva C; Trevisan DM; Peirasmaki D; Chen S; Savage SA; Larsson O; Ule J; Baranello L; Agostini F; Farnebo M
Article: NATURE COMMUNICATIONS. 2022;13(1):1015
Small Cajal body-associated RNA 2 (scaRNA2) regulates DNA repair pathway choice by inhibiting DNA-PK
Bergstrand S; O'Brien EM; Coucoravas C; Hrossova D; Peirasmaki D; Schmidli S; Dhanjal S; Pederiva C; Siggens L; Mortusewicz O; O'Rourke JJ; Farnebo M
Article: ONCOLOGY LETTERS. 2022;23(1):30
Evaluation of dyskerin expression and the Cajal body protein WRAP53β as potential prognostic markers for patients with primary vaginal carcinoma
Ranhem C; Larsson G; Lindqvist D; Sorbe B; Karlsson M; Farnebo M; Hellman K; Kovaleska L; Kashuba E; Andersson S
Article: CELL DEATH AND DISEASE. 2020;11(4):238
Biallelic mutations in WRAP53 result in dysfunctional telomeres, Cajal bodies and DNA repair, thereby causing Hoyeraal-Hreidarsson syndrome
Bergstrand S; Bohm S; Malmgren H; Norberg A; Sundin M; Nordgren A; Farnebo M
Article: CELL CHEMICAL BIOLOGY. 2019;26(10):1436-1449.e5
Neutralization of the Positive Charges on Histone Tails by RNA Promotes an Open Chromatin Structure
Dueva R; Akopyan K; Pederiva C; Trevisan D; Dhanjal S; Lindqvist A; Farnebo M
Article: ONCOLOGY REPORTS. 2017;38(4):2062-2068
WRAP53β, survivin and p16^INK4a expression as potential predictors of radiotherapy/chemoradiotherapy response in T2N0-T3N0 glottic laryngeal cancer
Tiefenbock-Hansson K; Haapaniemi A; Farnebo L; Palmgren B; Tarkkanen J; Farnebo M; Munck-Wikland E; Makitie A; Garvin S; Roberg K
Article: RNA BIOLOGY. 2017;14(6):804-813
Phosphorylation of the Cajal body protein WRAP53βby ATM promotes its involvement in the DNA damage response
Coucoravas C; Dhanjal S; Henriksson S; Bohm S; Farnebo M
Article: CELL DEATH AND DIFFERENTIATION. 2016;23(10):1648-1657
Splicing controls the ubiquitin response during DNA double-strand break repair
Pederiva C; Boehm S; Julner A; Farnebo M
Article: CELL DEATH AND DISEASE. 2016;7(6):e2267
Overexpression of the scaffold WD40 protein WRAP53β enhances the repair of and cell survival from DNA double-strand breaks
Rassoolzadeh H; Bohm S; Hedstrom E; Gad H; Helleday T; Henriksson S; Farnebo M
Article: CELL DEATH AND DISEASE. 2015;6(10):e1892
Downregulation of the cancer susceptibility protein WRAP53β in epithelial ovarian cancer leads to defective DNA repair and poor clinical outcome
Hedstrom E; Pederiva C; Farnebo J; Nodin B; Jirstrom K; Brennan DJ; Farnebo M
Article: NUCLEUS. 2015;6(5):417-424
The proximity ligation assay reveals that at DNA double-strand breaks WRAP53 associates with H2AX and controls interactions between RNF8 and MDC1
Rassoolzadeh H; Coucoravas C; Farnebo M
Article: PLOS ONE. 2015;10(10):e0139965
The Sub-Cellular Localization of WRAP53 Has Prognostic Impact in Breast Cancer
Silwal-Pandit L; Russnes H; Borgen E; Skarpeteig V; Vollan HKM; Schlichting E; Karesen R; Naume B; Borresen-Dale A-L; Farnebo M; Langerod A
Article: ORAL ONCOLOGY. 2015;51(1):24-30
Nuclear expression of WRAP53β is associated with a positive response to radiotherapy and improved overall survival in patients with head and neck squamous cell carcinoma
Garvin S; Tiefenbock K; Farnebo L; Thunell LK; Farnebo M; Roberg K
Article: GENES & DEVELOPMENT. 2014;28(24):2726-2738
The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair
Henriksson S; Rassoolzadeh H; Hedstrom E; Coucoravas C; Julner A; Goldstein M; Imreh G; Zhivotovsky B; Kastan MB; Helleday T; Farnebo M
Article: CELL DEATH AND DISEASE. 2011;2(1):e114
WRAP53 promotes cancer cell survival and is a potential target for cancer therapy
Mahmoudi S; Henriksson S; Farnebo L; Roberg K; Farnebo M
Article: PLOS BIOLOGY. 2010;8(11):e1000521
WRAP53 Is Essential for Cajal Body Formation and for Targeting the Survival of Motor Neuron Complex to Cajal Bodies
Mahmoudi S; Henriksson S; Weibrecht I; Smith S; Soderberg O; Stromblad S; Wiman KG; Farnebo M
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2010;37(1):15-20
Sorafenib induces apoptosis and autophagy in prostate cancer cells in vitro
Ullen A; Farnebo M; Thyrell L; Mahmoudi S; Kharaziha P; Lennartsson L; Grander D; Panaretakis T; Nilsson S
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):85-89
The p53 tumor suppressor: A master regulator of diverse cellular processes and therapeutic target in cancer
Farnebo M; Bykov VJN; Wiman KG
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(37):15756-15761
The p53 target Wig-1 regulates p53 mRNA stability through an AU-rich element
Vilborg A; Glahder JA; Wilhelm MT; Bersani C; Corcoran M; Mahmoudi S; Rosenstierne M; Grander D; Farnebo M; Norrild B; Wiman KG
Article: CELL CYCLE. 2009;8(15):2343-2346
Wrap53, a novel regulator of p53
Farnebo M
Article: MOLECULAR CELL. 2009;33(4):462-471
Wrap53, a Natural p53 Antisense Transcript Required for p53 Induction upon DNA Damage
Mahmoudi S; Henriksson S; Corcoran M; Mendez-Vidal C; Wiman KG; Farnebo M
Article: EXPERIMENTAL CELL RESEARCH. 2007;313(19):4015-4024
Interferon alpha induces cell death through interference with interleukin 6 signaling and inhibition of STAT3 activity
Thyrell L; Arulampalam V; Hjortsberg L; Farnebo M; Grander D; Tamm KP
Article: HUMAN MOLECULAR GENETICS. 2004;13(23):2925-2936
Disruption of a novel ectodermal neural cortex 1 antisense gene, ENC-1AS and identification of ENC-1 overexpression in hairy cell leukemia
Hammarsund M; Lerner M; Zhu CY; Merup M; Jansson M; Gahrton G; Kluin-Nelemans H; Einhorn S; Grandér D; Sangfelt O; Corcoran M
Article: GENES CHROMOSOMES AND CANCER. 2004;40(4):285-297
DLEU2 encodes an antisense RNA for the putative bicistronic RFP2/LEU5 gene in humans and mouse
Corcoran MM; Hammarsund M; Zhu CY; Lerner M; Kapanadze B; Wilson B; Larsson C; Forsberg L; Ibbotson RE; Stefan E; Oscier DG; Grandér D; Sangfelt O
Article: FEBS LETTERS. 2004;556(1-3):75-80
Characterization of a novel B-CLL candidate gene -: DLEU7 -: located in the 13q14 tumor suppressor locus
Hammarsund M; Corcoran MM; Wilson W; Zhu CY; Einhorn S; Sangfelt O; Grander D
Article: GENE. 2003;321:103-112
Distinct organization of the candidate tumor suppressor gene RFP2 in human and mouse:: multiple mRNA isoforms in both species- and human-specific antisense transcript RFP2OS
Baranova A; Hammarsund M; Ivanova DV; Skoblov M; Sangfelt O; Corcoran M; Borodina T; Makeeva N; Pestova A; Tyazhelova T; Nazarenko S; Gorreta F; Alsheddi T; Schlauch K; Nikitin E; Kapanadze B; Shagin D; Poltaraus A; Vorobiev AI; Zabarovsky E; Lukianov S; Chandhoke V; Ibbotson R; Oscier D; Einhorn S; Grander D; Yankovsky N
Article: HUMAN GENETICS. 2001;109(5):542-550
Identification and characterization of two novel human mitochondrial elongation factor genes, hEFG2 and hEFG1, phylogenetically conserved through evolution
Hammarsund M; Wilson W; Corcoran M; Merup M; Einhorn S; Grandér D; Sangfelt O
Article: GENOMICS. 2000;70(3):327-334
Comparative sequence analysis of a region on human chromosome 13q14, frequently deleted in B-cell chronic lymphocytic leukemia, and its homologous region on mouse chromosome 14
Kapanadze B; Makeeva N; Corcoran M; Jareborg N; Hammarsund M; Baranova A; Zabarovsky E; Vorontsova O; Merup M; Gahrton G; Jansson M; Yankovsky N; Einhorn S; Oscier D; Grandér D; Sangfelt O
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Editorial comment: NATURE REVIEWS MOLECULAR CELL BIOLOGY. 2020;21(2):65
RISE OF THE NEGLECTED REPEATS RNA
Farnebo M
Review: FRONTIERS IN MOLECULAR BIOSCIENCES. 2019;6:51
The Cajal Body Protein WRAP53β Prepares the Scene for Repair of DNA Double-Strand Breaks by Regulating Local Ubiquitination
Bergstrand S; O'Brien EM; Farnebo M
Editorial comment: CELL CYCLE. 2018;17(2):137-138
RNF8-The Achilles heel of DNA repair when splicing rules
Pederiva C; Farnebo M
Review: FRONTIERS IN GENETICS. 2015;6:91
On the road with WRAP53β: guardian of Cajal bodies and genome integrity
Henriksson S; Farnebo M
Letter: NATURE METHODS. 2011;8(11):892-893
Increasing the dynamic range of in situ PLA
Clausson C-M; Allalou A; Weibrecht I; Mahmoudi S; Farnebo M; Landegren U; Wahlby C; Soderberg O
Thesis / dissertation: 2003
Genetic changes in lymphoid leukemia
Hammarsund, Marianne

Anställningar

Lektor, Onkologi-Patologi, Karolinska Institutet, 2024-

Examina och utbildning

Docent, Experimentell onkologi, Karolinska Institutet, 2011
MEDICINE DOKTORSEXAMEN, Institutionen för onkologi-patologi, Karolinska Institutet, 2003
Medicine Magisterexamen, Karolinska Institutet, 1999

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