Maria Masucci

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: NATURE COMMUNICATIONS. 2023;14(1):8315
Remodeling of the ribosomal quality control and integrated stress response by viral ubiquitin deconjugases
Liu J; Nagy N; Ayala-Torres C; Aguilar-Alonso F; Morais-Esteves F; Xu S; Masucci MG
Article: AUTOPHAGY. 2021;17(11):3461-3474
The Epstein-Barr virus deubiquitinase BPLF1 targets SQSTM1/p62 to inhibit selective autophagy
Yla-Anttila P; Gupta S; Masucci MG
Article: PLOS PATHOGENS. 2021;17(9):e1009954
The Epstein-Barr virus deubiquitinating enzyme BPLF1 regulates the activity of topoisomerase II during productive infection
Li J; Nagy N; Liu J; Gupta S; Frisan T; Hennig T; Cameron DP; Baranello L; Masucci MG
Article: BIOCHEMICAL JOURNAL. 2021;478(12):2297-2308
Inhibition of selective autophagy by members of the herpesvirus ubiquitin-deconjugase family
Yla-Anttila P; Masucci MG
Article: ONCOGENE. 2020;39(3):603-616
The Epstein-Barr virus nuclear antigen-1 upregulates the cellular antioxidant defense to enable B-cell growth transformation and immortalization
Wang J; Nagy N; Masucci MG
Article: FRONTIERS IN IMMUNOLOGY. 2020;11:437
Interaction With 14-3-3 Correlates With Inactivation of the RIG-I Signalosome by Herpesvirus Ubiquitin Deconjugases
Gupta S; Yla-Anttila P; Sandalova T; Achour A; Masucci MG
Article: CELLULAR MICROBIOLOGY. 2019;21(12):e13099
Infection with genotoxin-producing Salmonella enterica synergises with loss of the tumour suppressor APC in promoting genomic instability via the PI3K pathway in colonic epithelial cells
Martin OCB; Bergonzini A; D'Amico F; Chen P; Shay JW; Dupuy J; Svensson M; Masucci MG; Frisan T
Article: PLOS PATHOGENS. 2019;15(11):e1008146
14-3-3 scaffold proteins mediate the inactivation of trim25 and inhibition of the type I interferon response by herpesvirus deconjugases
Gupta S; Yla-Anttila P; Sandalova T; Sun R; Achour A; Masucci MG
Article: INTERNATIONAL JOURNAL OF CANCER. 2019;144(1):98-109
A bacterial genotoxin causes virus reactivation and genomic instability in Epstein-Barr virus infected epithelial cells pointing to a role of co-infection in viral oncogenesis
Frisan T; Nagy N; Chioureas D; Terol M; Grasso F; Masucci MG
Article: PLOS PATHOGENS. 2018;14(1):e1006852
Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome
Gupta S; Yla-Anttila P; Callegari S; Tsai M-H; Delecluse H-J; Masucci MG
Article: PLOS PATHOGENS. 2017;13(4):e1006338
The Epstein-Barr virus miR-BHRF1-1 targets RNF4 during productive infection to promote the accumulation of SUMO conjugates and the release of infectious virus
Li J; Callegari S; Masucci MG
Article: ONCOGENE. 2016;35(29):3807-3816
Oxidative stress enables Epstein-Barr virus-induced B-cell transformation by posttranscriptional regulation of viral and cellular growth-promoting factors
Chen X; Kamranvar SA; Masucci MG
Article: FEBS JOURNAL. 2014;281(21):4935-4950
Epstein-Barr virus encoded microRNAs target SUMO-regulated cellular functions
Callegari S; Gastaldello S; Faridani OR; Masucci MG
Article: ONCOGENE. 2013;32(49):5522-5530
Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein-Barr virus
Kamranvar SA; Chen X; Masucci MG
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2013;433(4):390-395
An N-terminal SIAH-interacting motif regulates the stability of the ubiquitin specific protease (USP)-19
Velasco K; Zhao B; Callegari S; Altun M; Liu H; Hassink G; Masucci MG; Lindsten K
Article: NUCLEIC ACIDS RESEARCH. 2013;41(5):2950-2962
The Epstein-Barr virus nuclear antigen-1 reprograms transcription by mimicry of high mobility group A proteins
Coppotelli G; Mughal N; Callegari S; Sompallae R; Caja L; Luijsterburg MS; Dantuma NP; Moustakas A; Masucci MG
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2013;431(4):706-711
The Gly-Ala repeat modulates the interaction of Epstein-Barr virus nuclear antigen-1 with cellular chromatin
Coppotelli G; Mughal N; Masucci MG
Article: PLOS ONE. 2013;8(5):e62783
Interaction of Gamma-Herpesvirus Genome Maintenance Proteins with Cellular Chromatin
Mughal N; Coppotelli G; Callegari S; Gastaldello S; Masucci MG
Article: CELLULAR MICROBIOLOGY. 2013;15(1):98-113
Chronic exposure to the cytolethal distending toxins of Gram-negative bacteria promotes genomic instability and altered DNA damage response
Guidi R; Guerra L; Levi L; Stenerlow B; Fox JG; Josenhans C; Masucci MG; Frisan T
Article: PLOS PATHOGENS. 2013;9(10):e1003664
Caspase-1 Promotes Epstein-Barr Virus Replication by Targeting the Large Tegument Protein Deneddylase to the Nucleus of Productively Infected Cells
Gastaldello S; Chen X; Callegari S; Masucci MG
Article: FASEB JOURNAL. 2012;26(12):5060-5070
Ubiquitin C-terminal hydrolase-L1 interacts with adhesion complexes and promotes cell migration, survival, and anchorage independent growth
Frisan T; Coppotelli G; Dryselius R; Masucci MG
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;427(3):490-496
The ubiquitin specific protease-4 (USP4) interacts with the S9/Rpn6 subunit of the proteasome
Zhao B; Velasco K; Sompallae R; Pfirrmann T; Masucci MG; Lindsten K
Article: JOURNAL OF MOLECULAR CELL BIOLOGY. 2012;4(4):242-251
Herpes virus deneddylases interrupt the cullin-RING ligase neddylation cycle by inhibiting the binding of CAND1
Gastaldello S; Callegari S; Coppotelli G; Hildebrand S; Song M; Masucci MG
Article: CANCER IMMUNOLOGY IMMUNOTHERAPY. 2012;61(6):881-892
Remodeling of the epitope repertoire of a candidate idiotype vaccine by targeting to lysosomal degradation in dendritic cells
Martorelli D; Coppotelli G; Muraro E; Dolcetti R; Masucci MG
Article: JOURNAL OF CELL SCIENCE. 2011;124(16):2735-2742
Bacterial genotoxin triggers FEN1-dependent RhoA activation, cytoskeleton remodeling and cell survival
Guerra L; Guidi R; Slot I; Callegari S; Sompallae R; Pickett CL; Astrom S; Eisele F; Wolf D; Sjogren C; Masucci MG; Frisan T
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2011;286(22):19565-19575
High Avidity Binding to DNA Protects Ubiquitylated Substrates from Proteasomal Degradation
Coppotelli G; Mughal N; Marescotti D; Masucci MG
Article: LEUKEMIA. 2011;25(6):1017-1025
The Epstein-Barr virus nuclear antigen-1 promotes telomere dysfunction via induction of oxidative stress
Kamranvar SA; Masucci MG
Article: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY. 2011;301(3):213-224
Helicobacter pylori affects the cellular deubiquitinase USP7 and ubiquitin-regulated components TRAF6 and the tumour suppressor p53
Coombs N; Sompallae R; Olbermann P; Gastaldello S; Goeppel D; Masucci MG; Josenhans C
Article: PLOS ONE. 2011;6(2):e16960
Thioredoxin 80-Activated-Monocytes (TAMs) Inhibit the Replication of Intracellular Pathogens
Cortes-Bratti X; Basseres E; Herrera-Rodriguez F; Botero-Kleiven S; Coppotelli G; Andersen JB; Masucci MG; Holmgren A; Chaves-Olarte E; Frisan T; Avila-Carino J
Article: PLOS BIOLOGY. 2010;8(11):e1000545
The Translation Initiation Factor 3f (eIF3f) Exhibits a Deubiquitinase Activity Regulating Notch Activation
Moretti J; Chastagner P; Gastaldello S; Heuss SF; Dirac AM; Bernards R; Masucci MG; Israel A; Brou C
Article: CELLULAR MICROBIOLOGY. 2010;12(11):1622-1633
The ubiquitin C-terminal hydrolase UCH-L1 promotes bacterial invasion by altering the dynamics of the actin cytoskeleton
Basseres E; Coppotelli G; Pfirrmann T; Andersen JB; Masucci M; Frisan T
Article: PLOS ONE. 2010;5(8):e12052
Transcription Profiling of Epstein-Barr Virus Nuclear Antigen (EBNA)-1 Expressing Cells Suggests Targeting of Chromatin Remodeling Complexes
Sompallae R; Callegari S; Kamranvar SA; Masucci MG
Article: NATURE CELL BIOLOGY. 2010;12(4):351-361
A deneddylase encoded by Epstein-Barr virus promotes viral DNA replication by regulating the activity of cullin-RING ligases
Gastaldello S; Hildebrand S; Faridani O; Callegari S; Palmkvist M; Di Guglielmo C; Masucci MG
Article: IMMUNOLOGY. 2010;129(3):386-395
Characterization of an human leucocyte antigen A2-restricted Epstein-Barr virus nuclear antigen-1-derived cytotoxic T-lymphocyte epitope
Marescotti D; Destro F; Baldisserotto A; Marastoni M; Coppotelli G; Masucci M; Gavioli R
Article: ONCOGENE. 2009;28(45):3997-4008
Three Epstein-Barr virus latency proteins independently promote genomic instability by inducing DNA damage, inhibiting DNA repair and inactivating cell cycle checkpoints
Gruhne B; Sompallae R; Masucci MG
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2009;13(8B):1666-1678
The ubiquitin C-terminal hydrolase UCH-L1 regulates B-cell proliferation and integrin activation
Rolen U; Freda E; Xie J; Pfirrmann T; Frisan T; Masucci MG
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2009;13(8B):1886-1895
The ubiquitin specific protease 4 (USP4) is a new player in the Wnt signalling pathway
Zhao B; Schlesiger C; Masucci MG; Lindsten K
Article: EMBO REPORTS. 2009;10(7):755-761
The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates
Hassink GC; Zhao B; Sompallae R; Altun M; Gastaldello S; Zinin NV; Masucci MG; Lindsten K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(7):2313-2318
The Epstein-Barr virus nuclear antigen-1 promotes genomic instability via induction of reactive oxygen species
Gruhne B; Sompallae R; Marescotti D; Kamranvar SA; Gastaldello S; Masucci MG
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;68(6):579-588
Inhibition of Serine-Peptidase Activity Enhances the Generation of a Survivin-Derived HLA-A2-Presented CTL Epitope in Colon-Carcinoma Cells
Preta G; Marescotti D; Fortini C; Carcoforo P; Castelli C; Masucci M; Gavioli R
Article: GENE REGULATION AND SYSTEMS BIOLOGY. 2008;2:253-265
The MAPK Signaling Cascade is a Central Hub in the Regulation of Cell Cycle, Apoptosis and Cytoskeleton Remodeling by Tripeptidyl-Peptidase II
Sompallae R; Stavropoulou V; Houde M; Masucci MG
Article: JOURNAL OF VIROLOGY. 2008;82(21):10477-10486
Epstein-Barr Virus Encodes Three Bona Fide Ubiquitin-Specific Proteases
Sompallae R; Gastaldello S; Hildebrand S; Zinin N; Hassink G; Lindsten K; Haas J; Persson B; Masucci MG
Article: PLOS ONE. 2008;3(5):e2254
A Bacterial Cytotoxin Identifies the RhoA Exchange Factor Net1 as a Key Effector in the Response to DNA Damage
Guerra L; Carr HS; Richter-Dahlfors A; Masucci MG; Thelestam M; Frost JA; Frisan T
Article: CANCER BIOLOGY & THERAPY. 2007;6(12):1997-2004
Expression of immune-related molecules in primary EBV positive chinese nasopharyngeal carcinoma: Associated with latent membrane protein 1 (LMP1) expression
Li J; Zhang X-S; Xie D; Deng H-X; Gao Y-F; Chen Q-Y; Huang W-L; Masucci MG; Zeng Y-X
Article: PLOS ONE. 2007;2(11):e1122
Functional Inactivation of EBV-Specific T-Lymphocytes in Nasopharyngeal Carcinoma: Implications for Tumor Immunotherapy
Li J; Zeng X-H; Mo H-Y; Rolen U; Gao Y-F; Zhang X-S; Chen Q-Y; Zhang L; Zeng M-S; Li M-Z; Huang W-L; Wang X-N; Zeng Y-X; Masucci MG
Article: CANCER IMMUNOLOGY IMMUNOTHERAPY. 2007;56(10):1597-1604
Single administration of low dose cyclophosphamide augments the antitumor effect of dendritic cell vaccine
Liu J-Y; Wu Y; Zhang X-S; Yang J-L; Li H-L; Mao Y-Q; Wang Y; Cheng X; Li Y-Q; Xia J-C; Masucci M; Zeng Y-X
Article: ONCOGENE. 2007;26(35):5115-5123
Epstein-Barr virus promotes genomic instability in Burkitt's lymphoma
Kamranvar SA; Gruhne B; Szeles A; Masucci MG
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;346(2):415-425
TPPII promotes genetic instability by allowing the escape from apoptosis of cells with activated mitotic checkpoints
Stavropoulou V; Vasquez V; Cereser B; Freda E; Masucci MG
Article: JOURNAL OF CLINICAL VIROLOGY. 2006;36(1):50-59
Non-infectious fluorimetric assay for phenotyping of drug-resistant HIV proteinase mutants
Majerová-Uhlíková T; Dantuma NP; Lindsten K; Masucci MG; Konvalinka J
Article: MOLECULAR CARCINOGENESIS. 2006;45(4):260-269
Activity profiling of deubiquitinating enzymes in cervical carcinoma biopsies and cell lines
Rolén U; Kobzeva V; Gasparjan N; Ovaa H; Winberg G; Kisseljov F; Masucci MG
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2006;63(6):723-734
The ubiquitin-specific protease USP25 interacts with three sarcomeric proteins
Bosch-Comas A; Lindsten K; Gonzàlez-Duarte R; Masucci MG; Marfany G
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2005;35(10):2929-2939
Help signals provided by lymphokines modulate the activation and apoptotic programs induced by partially agonistic peptides in specific cytotoxic T lymphocytes
Uhlin M; Sandalova E; Masucci MG; Levitsky V
Article: HUMAN MOLECULAR GENETICS. 2005;14(19):2787-2799
Endoplasmic reticulum stress compromises the ubiquitin-proteasome system
Menéndez-Benito V; Verhoef LGGC; Masucci MG; Dantuma NP
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(26):9264-9269
Regulation of lck degradation and refractory state in CD81 cytotoxic T lymphocytes
Uhlin M; Masucci MG; Levitsky V
Article: MOLECULAR CELL. 2005;18(2):225-235
The UBA2 domain functions as an intrinsic stabilization signal that protects Rad23 from proteasomal degradation
Heessen S; Masucci MG; Dantuma NP
Article: CANCER RESEARCH. 2005;65(4):1361-1368
Mitotic infidelity and centrosome duplication errors in cells overexpressing tripeptidyl-peptidase II
Stavropoulou V; Xie JJ; Henriksson M; Tomkinson B; Imreh S; Masucci MG
Article: JOURNAL OF VIROLOGY. 2005;79(4):2230-2239
Hepatitis C virus core protein induces an anergic state characterized by decreased interleukin-2 production and perturbation of mitogen-activated protein kinase responses
Sundström S; Ota S; Dimberg LY; Masucci MG; Bergqvist A
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;60(6):592-599
Differential regulation of MHC class-I-restricted and unrestricted cytotoxicity by the Us3 protein kinase of herpes simplex virus-1
Cartier A; Masucci MG
Article: NATURE MEDICINE. 2004;10(12):1321-1328
Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors
Issaeva N; Bozko P; Enge M; Protopopova M; Verhoef LGGC; Masucci M; Pramanik A; Selivanova G
Article: JOURNAL OF GENERAL VIROLOGY. 2004;85(Pt 10):2767-2778
Capacity of Epstein-Barr virus to infect monocytes and inhibit their development into dendritic cells is affected by the cell type supporting virus replication
Guerreiro-Cacais AO; Li LQ; Donati D; Bejarano MT; Morgan A; Masucci MG; Hutt-Fletcher L; Levitsky V
Article: CLINICAL TRANSPLANTATION. 2004;18(5):518-524
Effect of combined T- and B-cell depletion of allogeneic HLA-mismatched bone marrow graft on the magnitude and kinetics of Epstein-Barr virus load in the peripheral blood of bone marrow transplant recipients
Liu DR; Tammik C; Zou JZ; Ernberg I; Masucci MG; Ringden O; Levitsky V
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(9):3011-3016
Regulation of expression of Bcl-2 protein family member Bim by T cell receptor triggering
Sandalova E; Wei CH; Masucci MG; Levitsky V
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(8):2253-2258
Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells
Ovaa H; Kessler BM; Rolén U; Galardy PJ; Ploegh HL; Masucci MG
Article: FEBS LETTERS. 2003;555(2):397-404
Inhibition of ubiquitin/proteasome-dependent proteolysis in Saccharomyces cerevisiae by a Gly-Ala repeat
Heessen S; Dantuma NP; Tessarz P; Jellne M; Masucci MG
Article: CELL DEATH AND DIFFERENTIATION. 2003;10(12):1320-1328
The herpes simplex virus-1 Us3 protein kinase blocks CD8T cell lysis by preventing the cleavage of Bid by granzyme B
Cartier A; Broberg E; Komai T; Henriksson M; Masucci MG
Article: EXPERIMENTAL CELL RESEARCH. 2003;291(1):242-250
The Us3 protein kinase of herpes simplex virus 1 blocks apoptosis and induces phosporylation of the Bcl-2 family member Bad
Cartier A; Komai T; Masucci MG
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;105(2):369-375
Activation of epitope-specific memory cytotoxic T lymphocyte responses by synthetic peptides
Reali E; Guerrini R; Giori B; Borghi M; Marastoni M; Tomatis R; Traniello S; Masucci MG; Gavioli R
Article: NATURE BIOTECHNOLOGY. 2003;21(8):897-902
A transgenic mouse model of the ubiquitin/proteasome system
Lindsten K; Menéndez-Benito V; Masucci MG; Dantuma NP
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(21):18877-18883
The hepatitis C virus core protein modulates T cell responses by inducing spontaneous and altering T-cell receptor-triggered Ca²⁺ oscillations
Bergqvist A; Sundström S; Dimberg LY; Gylfe E; Masucci MG
Article: BRAIN PATHOLOGY. 2003;13(2):165-175
Soluble factors released by virus specific activated cytotoxic T-lymphocytes induce apoptotic death of astroglioma cell lines
Sabri F; Chiodi F; Piret JP; Wei CH; Major E; Westermark B; Masucci MG; Levitsky V
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2003;57(2):99-106
Pharmacological disintegration of lipid rafts decreases specific tetramer binding and disrupts the CD3 complex and CD8 heterodimer in human cytotoxic T lymphocytes
Uhlin M; Masucci MG; Levitsky V
Article: SEMINARS IN CANCER BIOLOGY. 2003;13(1):69-76
The ubiquitin/proteasome system in Epstein-Barr virus latency and associated malignancies
Dantuma NP; Masucci MG
Article: INTERNATIONAL JOURNAL OF CANCER. 2002;101(6):532-538
Proteasome inhibitors reconstitute the presentation of cytotoxic T-cell epitopes in Epstein-Barr virus-associated tumors
Gavioli R; Vertuani S; Masucci MG
Article: HUMAN MOLECULAR GENETICS. 2002;11(22):2689-2700
Aggregate formation inhibits proteasomal degradation of polyglutamine proteins
Verhoef LGGC; Lindsten K; Masucci MG; Dantuma NP
Article: HUMAN IMMUNOLOGY. 2002;63(10):821-833
Tetramer binding and secretion of interferon-γ in response to antigenic stimulation are compatible with a range of affinities of MHC:TCR interaction and distinct programs of cytotoxic T-lymphocyte activation
Wei CH; Uhlin M; Masucci MG; Levitsky V
Article: FEBS LETTERS. 2002;522(1-3):93-98
Inhibition of ubiquitin-dependent proteolysis by a synthetic glycine-alanine repeat peptide that mimics an inhibitory viral sequence
Leonchiks A; Stavropoulou V; Sharipo A; Masucci MG
Article: BLOOD. 2002;99(10):3725-3734
Epstein-Barr virus inhibits the development of dendritic cells by promoting apoptosis of their monocyte precursors in the presence of granulocyte macrophage-colony-stimulating factor and interleukin-4
Li LQ; Liu DR; Hutt-Fletcher L; Morgan A; Masucci MG; Levitsky V
Article: JOURNAL OF CELL BIOLOGY. 2002;157(3):417-427
Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation
Lindsten K; de Vrij FMS; Verhoef LGGC; Fischer DF; van Leeuwen FW; Hol EM; Masucci MG; Dantuma NP
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2002;99(7):4550-4555
MYC overexpression imposes a nonimmunogenic phenotype on Epstein-Barr virus-infected B cells
Staege MS; Lee SP; Frisan T; Mautner J; Scholz S; Pajic A; Rickinson AB; Masucci MG; Polack A; Bornkamm GW
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2002;99(3):1532-1537
Functional p53 chimeras containing the Epstein-Barr virus Gly-Ala repeat are protected from Mdm2-and HPV-E6-induced proteolysis
Heessen S; Leonchiks A; Issaeva N; Sharipo A; Selivanova G; Masucci MG; Dantuma NP
Article: CELLULAR MICROBIOLOGY. 2002;4(2):87-99
The Haemophilus ducreyi cytolethal distending toxin activates sensors of DNA damage and repair complexes in proliferating and non-proliferating cells
Li LQ; Sharipo A; Chaves-Olarte E; Masucci MG; Levitsky V; Thelestam M; Frisan T
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2001;45(9):2616-2622
Cell-based fluorescence assay for human immunodeficiency virus type 1 protease activity
Lindsten K; Uhlíková T; Konvalinka J; Masucci MG; Dantuma NP
Article: FEBS LETTERS. 2001;499(1-2):137-142
cis-inhibition of proteasomal degradation by viral repeats:: impact of length and amino acid composition
Sharipo A; Imreh M; Leonchiks A; Brändén CI; Masucci MG
Article: NATURE CELL BIOLOGY. 2001;3(3):283-288
c-myc overexpression activates alternative pathways for intracellular proteolysis in lymphoma cells
Gavioli R; Frisan T; Vertuani S; Bornkamm GW; Masucci MG
Article: JOURNAL OF IMMUNOLOGY. 2001;166(2):989-995
Different programs of activation-induced cell death are triggered in mature activated CTL by immunogenic and partially agonistic peptide ligands
Wei CH; Yagita H; Masucci MG; Levitsky V
Article: METHODS IN MOLECULAR BIOLOGY. 2001;174:213-216
Limiting dilution assay.
Frisan T; Levitsky V; Masucci M
Article: METHODS IN MOLECULAR BIOLOGY. 2001;174:209-211
Determination of antigen and fine peptide specificity of EBV-specific CTLs.
Levitsky V; Frisan T; Masucci M
Article: METHODS IN MOLECULAR BIOLOGY. 2001;174:203-208
Generation of polyclonal EBV-specific CTL cultures and clones.
Levitsky V; Frisan T; Masucci M
Article: METHODS IN MOLECULAR BIOLOGY. 2001;174:199-201
Regression assay.
Frisan T; Levitsky V; Masucci M
Article: METHODS IN MOLECULAR BIOLOGY. 2001;174:125-127
Generation of lymphoblastoid cell lines (LCLs).
Frisan T; Levitsky V; Masucci M
Article: INTERNATIONAL JOURNAL OF CANCER. 2000;88(6):881-888
Variations in proteasome subunit composition and enzymatic activity in B-lymphoma lines and normal B cells
Frisan T; Levitsky V; Masucci MG
Article: HUMAN IMMUNOLOGY. 2000;61(10):972-984
Supermotif peptide binding and degeneracy of MHC: Peptide recognition in an EBV peptide-specific CTL response with highly restricted TCR usage
Levitsky V; Liu DR; Southwood S; Levitskaya J; Sette A; Masucci MG
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(31):23491-23499
Degradation of the epstein-barr virus latent membrane protein 1 (LMP1) by the ubiquitin-proteasome pathway. Targeting via ubiquitination of the N-terminal residue.
Aviel S; Winberg G; Massucci M; Ciechanover A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2000;97(15):8381-8385
Inhibition of proteasomal degradation by the Gly-Ala repeat of Epstein-Barr virus is influenced by the length of the repeat and the strength of the degradation signal
Dantuma NP; Heessen S; Lindsten K; Jellne M; Masucci MG
Article: NATURE BIOTECHNOLOGY. 2000;18(5):538-543
Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells
Dantuma NP; Lindsten K; Glas R; Jellne M; Masucci MG
Article: JOURNAL OF IMMUNOLOGY. 2000;164(9):4513-4521
Evidence of selective processing of immunodominant epitopes in virally infected cells.
Zhang QJ; Chen SS; Saari CA; Massuci MG; Tufaro F; Jefferies WA
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2000;51(4):361-371
Effect of interleukin-7 on the in vitro development and maturation of monocyte derived human dendritic cells
Li LQ; Masucci MG; Levitsky V
Article: BLOOD. 2000;95(3):807-814
Epstein-Barr virus (EBV) load in bone marrow transplant recipients at risk to develop posttransplant lymphoproliferative disease:: prophylactic infusion of EBV-specific cytotoxic T cells
Gustafsson Å; Levitsky V; Zou JZ; Frisan T; Dalianis T; Ljungman P; Ringden O; Winiarski J; Ernberg I; Masucci MG
Article: INTERNATIONAL JOURNAL OF CANCER. 1999;83(6):772-779
CD40 cross-linking enhances the immunogenicity of Burkitt's-lymphoma cell lines
Frisan T; Donati D; Cervenak L; Wilson J; Masucci MG; Bejarano M
Article: JOURNAL OF IMMUNOLOGY. 1999;163(5):2601-2609
A partially agonistic peptide acts as a selective inducer of apoptosis in CD8⁺ CTLs
Wei CH; Beeson C; Masucci MG; Levitsky V
Article: JOURNAL OF IMMUNOLOGY. 1999;162(1):106-113
A single specific amino acid residue in peptide antigens is sufficient to activate memory CTL: Potential role of cross-reactive peptides in memory T cell maintenance
Reali E; Guerrini R; Marastoni M; Tomatis R; Masucci MG; Traniello S; Gavioli R
Article: FEBS LETTERS. 1998;440(3):365-369
Random coil conformation of a Gly/Ala-rich insert in IκBα excludes structural stabilization as the mechanism for protection against proteasomal degradation
Leonchiks A; Liepinsh E; Barishev M; Sharipo A; Masucci MG; Otting G
Article: BLOOD. 1998;92(11):4256-4262
Interleukin-10 abrogates the inhibition of Epstein-Barr virus-induced B-cell transformation by memory T-cell responses
Bejarano MT; Masucci MG
Article: NATURE MEDICINE. 1998;4(8):939-944
A minimal glycine-alanine repeat prevents the interaction of ubiquitinated IκBα with the proteasome:: A new mechanism for selective inhibition of proteolysis
Sharipo A; Imreh M; Leonchiks A; Imreh S; Masucci MG
Article: JOURNAL OF IMMUNOLOGY. 1998;161(2):594-601
The clonal composition of a peptide-specific oligoclonal CTL repertoire selected in response to persistent EBV infection is stable over time
Levitsky V; de Campos-Lima PO; Frisan T; Masucci MG
Article: JOURNAL OF IMMUNOLOGY. 1998;160(7):3281-3289
Phenotype-dependent differences in proteasome subunit composition and cleavage specificity in B cell lines
Frisan T; Levitsky V; Polack A; Masucci MG
Article: SEMINARS IN VIROLOGY. 1998;8(5):361-368
Avoiding immunity and apoptosis: Manipulation of the host environment by herpes simplex virus and Epstein-Barr virus
Hill AB; Masucci MG
Article: FEBS LETTERS. 1998;421(2):95-99
High structural side chain specificity required at the second position of immunogenic peptides to obtain stable MHC/peptide complexes
Gavioli R; Guerrini R; Masucci MG; Tomatis R; Traniello S; Marastoni M
Article: JOURNAL OF IMMUNOLOGY. 1997;159(11):5383-5390
Natural variants of the immunodominant HLA A11-restricted CTL epitope of the EBV nuclear antigen-4 are nonimmunogenic due to intracellular dissociation from MHC class I:peptide complexes
Levitsky V; Zhang QJ; Levitskaya J; Kurilla MG; Masucci MG
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1997;94(23):12616-12621
Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein-Barr virus nuclear antigen 1
Levitskaya J; Sharipo A; Leonchiks A; Ciechanover A; Masucci MG
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 1997;186(1):83-89
Epitope-dependent selection of highly restricted or diverse T cell receptor repertoires in response to persistent infection by Epstein-Barr virus
deCamposLima PO; Levitsky V; Imreh MP; Gavioli R; Masucci MG
Article: INTERNATIONAL JOURNAL OF CANCER. 1996;68(2):251-258
Defective presentation of MHC class I-restricted cytotoxic T-cell epitopes in Burkitt's lymphoma cells
Frisan T; Zhang QJ; Levitskaya J; Coram M; Kurilla MG; Masucci MG
Article: HUMAN IMMUNOLOGY. 1996;49(1):1-12
HLA-A11-mediated protection from NK cell-mediated lysis - Role of HLA-A11-presented peptides
Gavioli R; Zhang QJ; Masucci MG
Article: INTERNATIONAL IMMUNOLOGY. 1996;8(6):927-938
Solvent exposed side chains of peptides bound to HLA A*1101 have similar effects on the reactivity of alloantibodies and specific TCR
Zhang QJ; Lindquist Y; Levitsky V; Masucci MG
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 1996;183(3):915-926
The life span of major histocompatibility complex-peptide complexes influences the efficiency of presentation and immunogenicity of two class I-restricted cytotoxic T lymphocyte epitopes in the Epstein-Barr virus nuclear antigen 4
Levitsky V; Zhang QJ; Levitskaya J; Masucci MG
Article: SEMINARS IN VIROLOGY. 1996;7(1):75-82
Strategies of immunoescape in Epstein-Barr virus persistence and pathogenesis
deCamposLima PO; Levitskaya J; Frisan T; Masucci MG
Article: BLOOD. 1995;86(4):1493-1501
LOCAL SUPPRESSION OF EPSTEIN-BARR-VIRUS (EBV)-SPECIFIC CYTOTOXICITY IN BIOPSIES OF EBV-POSITIVE HODGKINS-DISEASE
FRISAN T; SJOBERG J; DOLCETTI R; BOIOCCHI M; DE RE V; CARBONE A; BRAUTBAR C; BATTAT S; BIBERFELD P; ECKMAN M; OST O; CHRISTENSSON B; SUNDSTROM C; BJORKHOLM M; PISA P; MASUCCI MG
Article: CANCER RESEARCH. 1995;55(16):3675-3681
IDENTIFICATION AND CHARACTERIZATION OF AN EPSTEIN-BARR VIRUS-SPECIFIC T-CELL RESPONSE IN THE PATHOLOGICAL TISSUE OF A PATIENT WITH HODGKINS-DISEASE
DOLCETTI R; FRISAN T; SJOBERG J; DECAMPOSLIMA PO; PISA P; DE RE V; GLOGHINI A; RIZZO S; MASUCCI MG; BOIOCCHI M
Article: INTERNATIONAL JOURNAL OF CANCER. 1995;62(1):90-96
MECHANISMS OF ALLELE-SELECTIVE DOWN-REGULATION OF HLA CLASS-I IN BURKITTS-LYMPHOMA
IMREH MP; ZHANG QJ; DECAMPOSLIMA PO; IMREH S; KRAUSA P; BROWNING M; KLEIN G; MASUCCI MG
Article: NATURE. 1995;375(6533):685-688
INHIBITION OF ANTIGEN-PROCESSING BY THE INTERNAL REPEAT REGION OF THE EPSTEIN-BARR-VIRUS NUCLEAR ANTIGEN-1
LEVITSKAYA J; CORAM M; LEVITSKY V; IMREH S; STEIGERWALDMULLEN PM; KLEIN G; KURILLA MG; MASUCCI MG
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1995;206(1):8-14
EFFECT OF ANCHOR RESIDUE MODIFICATIONS ON THE STABILITY OF HLA-A11/PEPTIDE COMPLEXES
GAVIOLI R; ZHANG QJ; MARASTONI M; GUERRINI R; REALI E; TOMATIS R; MASUCCI MG; TRANIELLO S
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Alla övriga publikationer

Review: SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. 2022;132:185-192
Herpesvirus ubiquitin deconjugases
Masucci MG
Review: BIOMOLECULES. 2020;10(8):E1137-1137
Viral Ubiquitin and Ubiquitin-Like Deconjugases-Swiss Army Knives for Infection
Masucci MG
Corrigendum: ONCOGENE. 2020;39(9):2028
The Epstein-Barr virus nuclear antigen-1 upregulates the cellular antioxidant defense to enable B-cell growth transformation and immortalization (vol 39, pg 603, 2020)
Wang J; Nagy N; Masucci MG
Editorial comment: MICROBIAL CELL. 2018;5(5):259-261
A novel mechanism for regulation of the type I IFN response by herpesvirus deconjugases
Gupta S; Yla-Anttila P; Masucci MG
Review: VIRUSES-BASEL. 2017;9(8):E217-217
Regulation of Telomere Homeostasis during Epstein-Barr virus Infection and Immortalization
Kamranvar SA; Masucci MG
Review: SEMINARS IN CANCER BIOLOGY. 2014;26:43-51
Tumor viruses and replicative immortality - Avoiding the telomere hurdle
Chen X; Kamranvar SA; Masucci MG
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2014;26:1-3
Emerging topics in human tumor virology
Masucci MG; Rickinson AB
Review: SEMINARS IN CANCER BIOLOGY. 2009;19(6):394-400
EBV and genomic instability-A new look at the role of the virus in the pathogenesis of Burkitt's lymphoma
Gruhne B; Kamranvar SA; Masucci MG; Sompallae R
Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2006;64(6):581-587
Is the activity of partially agonistic MHC:Peptide ligands dependent on the quality of immunological help?
Uhlin M; Masucci M; Levitsky V
Letter: FASEB JOURNAL. 2006;20(7):1027-1028
GFP reporter mouse models of UPS proteolytic function
Lindsten K; Menendez-Benito V; Masucci MG; Dantuma NP
Review: ONCOGENE. 2004;23(11):2107-2115
Epstein-Barr virus oncogenesis and the ubiquitin-proteasome system
Masucci MG
Review: JOURNAL OF CELLULAR PHYSIOLOGY. 2003;196(2):207-218
Epstein-Barr virus: Induction and control of cell transformation
Dolcetti R; Masucci MG
Review: FEBS LETTERS. 2002;529(1):22-26
Stabilization signals: a novel regulatory mechanism in the ubiquitin/proteasome system
Dantuma NP; Masucci MG
Review: VIRUS RESEARCH. 2002;88(1-2):71-86
Manipulation of immune responses by Epstein-Barr virus
Levitsky V; Masucci MG
Review: NANOPARTICLES FOR RATIONAL VACCINE DESIGN. 2002;269:23-36
Avoiding proteasomal processing: The case of EBNA1
Dantuma NP; Sharipo A; Masucci MG
Letter: NATURE BIOTECHNOLOGY. 2000;18(8):807
Ubiquitin/proteasome system - Reply
Masucci MG; Dantuma NP

Anställningar

Professor, Senior, Cell- och molekylärbiologi, Karolinska Institutet, 2025-2025
Professor, Cell- och molekylärbiologi, Karolinska Institutet, 2007-2024

Examina och utbildning

Docent, Tumörbiologi, Karolinska Institutet, 1988

Handledning

Bin Zhao, Functional studies of deubiquitinating enzymes., https://openarchive.ki.se/xmlui/handle/10616/41134, 2008

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Examina och utbildning

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