Margs Brennan

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: CELL DEATH AND DIFFERENTIATION. 2024;31(2):159-169
Combined absence of TRP53 target genes ZMAT3, PUMA and p21 cause a high incidence of cancer in mice
Brennan MS; Brinkmann K; Sola GR; Healey G; Gibson L; Gangoda L; Potts MA; Lieschke E; Wilcox S; Strasser A; Herold MJ; Janic A
Article: CELL DEATH AND DISEASE. 2020;11(10):877
Consequences of Zmat3 loss in c-MYC- and mutant KRAS-driven tumorigenesis.
Best SA; Vandenberg CJ; Abad E; Whitehead L; Guiu L; Ding S; Brennan MS; Strasser A; Herold MJ; Sutherland KD; Janic A
Article: BLOOD ADVANCES. 2020;4(19):4918-4923
MLL-TFE3: a novel and aggressive KMT2A fusion identified in infant leukemia.
Kosasih HJ; Davidson NM; Bjelosevic S; Morrish E; Brennan MS; Oshlack A; Johnstone RW; Brumatti G; Khaw SL; Ekert PG
Article: CELL DEATH AND DIFFERENTIATION. 2019;26(5):902-917
TRIM17 and TRIM28 antagonistically regulate the ubiquitination and anti-apoptotic activity of BCL2A1.
Lionnard L; Duc P; Brennan MS; Kueh AJ; Pal M; Guardia F; Mojsa B; Damiano M-A; Mora S; Lassot I; Ravichandran R; Cochet C; Aouacheria A; Potts PR; Herold MJ; Desagher S; Kucharczak J
Article: BLOOD. 2018;132(15):1573-1583
Humanized Mcl-1 mice enable accurate preclinical evaluation of MCL-1 inhibitors destined for clinical use.
Brennan MS; Chang C; Tai L; Lessene G; Strasser A; Dewson G; Kelly GL; Herold MJ
Article: NATURE. 2018;560(7717):253-257
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Baell JB; Leaver DJ; Hermans SJ; Kelly GL; Brennan MS; Downer NL; Nguyen N; Wichmann J; McRae HM; Yang Y; Cleary B; Lagiakos HR; Mieruszynski S; Pacini G; Vanyai HK; Bergamasco MI; May RE; Davey BK; Morgan KJ; Sealey AJ; Wang B; Zamudio N; Wilcox S; Garnham AL; Sheikh BN; Aubrey BJ; Doggett K; Chung MC; de Silva M; Bentley J; Pilling P; Hattarki M; Dolezal O; Dennis ML; Falk H; Ren B; Charman SA; White KL; Rautela J; Newbold A; Hawkins ED; Johnstone RW; Huntington ND; Peat TS; Heath JK; Strasser A; Parker MW; Smyth GK; Street IP; Monahan BJ; Voss AK; Thomas T
Article: NATURE MEDICINE. 2018;24(7):947-953
DNA repair processes are critical mediators of p53-dependent tumor suppression.
Janic A; Valente LJ; Wakefield MJ; Di Stefano L; Milla L; Wilcox S; Yang H; Tai L; Vandenberg CJ; Kueh AJ; Mizutani S; Brennan MS; Schenk RL; Lindqvist LM; Papenfuss AT; O'Connor L; Strasser A; Herold MJ
Article: NATURE. 2016;538(7626):477-482
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models.
Kotschy A; Szlavik Z; Murray J; Davidson J; Maragno AL; Le Toumelin-Braizat G; Chanrion M; Kelly GL; Gong J-N; Moujalled DM; Bruno A; Csekei M; Paczal A; Szabo ZB; Sipos S; Radics G; Proszenyak A; Balint B; Ondi L; Blasko G; Robertson A; Surgenor A; Dokurno P; Chen I; Matassova N; Smith J; Pedder C; Graham C; Studeny A; Lysiak-Auvity G; Girard A-M; Gravé F; Segal D; Riffkin CD; Pomilio G; Galbraith LCA; Aubrey BJ; Brennan MS; Herold MJ; Chang C; Guasconi G; Cauquil N; Melchiore F; Guigal-Stephan N; Lockhart B; Colland F; Hickman JA; Roberts AW; Huang DCS; Wei AH; Strasser A; Lessene G; Geneste O
Article: CELL REPORTS. 2015;10(8):1422-1432
An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations in vivo.
Aubrey BJ; Kelly GL; Kueh AJ; Brennan MS; O'Connor L; Milla L; Wilcox S; Tai L; Strasser A; Herold MJ

Alla övriga publikationer

Letter: HEMASPHERE. 2024;8(2):e1
A novel MYB::PAIP1 oncogenic fusion in pediatric blastic plasmacytoid dendritic cell neoplasm (BPDCN) is dependent on BCL2 expression and is sensitive to venetoclax
Kosasih HJ; Healey G; Brennan MS; Bjelosevic S; Sadras T; Jalud FB; Ibnat T; Ng AP; Mayoh C; Mao J; Tax G; Ludlow LEA; Johnstone RW; Herold MJ; Khaw SL; de Bock CE; Ekert PG
Letter: CELL DEATH AND DIFFERENTIATION. 2022;29(5):1074-1076
Loss of TRP53 reduces but does not overcome dependency of lymphoma cells on MCL-1
Aubrey BJ; Brennan MS; Diepstraten ST; Wang Z; Chang C; Herold MJ; Strasser A; Kelly GL
Letter: CELL DEATH AND DISEASE. 2014;5(12):e1553
Characterisation of a novel A1-specific monoclonal antibody.
Lang MJ; Brennan MS; O'Reilly LA; Ottina E; Czabotar PE; Whitlock E; Fairlie WD; Tai L; Strasser A; Herold MJ

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