Margareta Wilhelm
Om mig
Margareta Wilhelm är docent i tumörbiologi vid institutionen för mikrobiologi, tumör- och cellbiologi. Hon tog en magisterexamen i molekylärbiologi vid Umeå universitet och avlade sin doktorsexamen i experimentell onkologi 2003 vid Karolinska Institutet, följt av postdoktoral utbildning vid Campbell Family Cancer Research Institute i Toronto, Kanada. Dr. Wilhelm har tilldelats en forskarassistenttjänst från Vetenskapsrådet,
- Young Investigator Award från Cancerfonden, samt en fakultetsfinansierad seniorforskartjänst vid Karolinska Institutet.
För närvarande innehar hon en högre forskartjänst inom barncancerforskning från Barncancerfonden.
Forskningsbeskrivning
Forskargruppen fokuserar på att förstå mekanismer som reglerar tumörinitiering och -progression med ett särskilt intresse för tumörmikromiljön och infiltrerande immunceller. Vi använder transgena modeller, cellulär reprogrammering, stamceller, och organoider för att modellera tumörutveckling.
Undervisning
- Docent in Tumor Biology
Program Director Research education program in Tumor Biology and Oncology
(FoTO)
Study Director Elective track in Tumor Biology Biomedicine Master program
Course Organizer and Teacher Biomedicine Master program
Artiklar
- Journal article: NEURO-ONCOLOGY. 2024;:noae210
- Article: NEURO-ONCOLOGY. 2024;26(9):1685-1699
- Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2022;79(10):535
- Article: FRONTIERS IN MOLECULAR BIOSCIENCES. 2022;9:823195
- Article: CANCERS. 2021;13(21):5493
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(10):e2017089118
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(33):20127-20138
- Article: CELL DEATH AND DISEASE. 2020;11(1):52
- Article: CELL DEATH AND DISEASE. 2019;10(9):663
- Article: STEM CELL RESEARCH. 2019;34:101356
- Article: ONCOGENE. 2018;37(27):3729-3739
- Article: CELLULAR ONCOLOGY (DORDRECHT). 2017;40(6):631-638
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(1):220-225
- Article: CELL DEATH AND DISEASE. 2014;5(10):e1484
- Article: EMBO REPORTS. 2014;15(4):383-391
- Article: CELL DEATH AND DIFFERENTIATION. 2013;20(2):293-301
- Article: PHYSICS IN MEDICINE AND BIOLOGY. 2012;57(22):7431-7441
- Article: ONCOGENE. 2010;29(49):6442-6451
- Article: GENES & DEVELOPMENT. 2010;24(6):549-560
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(37):15756-15761
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(3):797-802
- Article: GENES & DEVELOPMENT. 2008;22(19):2677-2691
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2008;38(1):64-72
- Article: FEBS LETTERS. 2002;524(1-3):69-72
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2002;30(9):1991-1996
- Article: ONCOGENE. 2001;20(39):5466-5474
- Visa fler
Alla övriga publikationer
- Preprint: BIORXIV. 2024
- Review: CANCERS. 2022;14(20):5009
- Preprint: BIORXIV. 2021
- Preprint: BIORXIV. 2020
- Meeting abstract: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019;139(9):S298
- Review: CELL DEATH DISCOVERY. 2018;4:7
- Corrigendum: CELL DEATH AND DISEASE. 2018;9(6):690
- Corrigendum: CELL DEATH AND DISEASE. 2018;9:681
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):311
- Review: SEMINARS IN CANCER BIOLOGY. 2011;21(4):256-266
- Review: CELL DEATH AND DIFFERENTIATION. 2011;18(9):1434-1440
- Review: JOURNAL OF MOLECULAR MEDICINE. 2010;88(7):645-652
- Book chapter: ZINC FINGER PROTEINS: MOLECULAR BIOLOGY INTELLIGENCE UNIT. 2005;p. 76-79
- Book chapter: TRANSCRIPTION FACTORS: HANDBOOK OF EXPERIMENTAL PHARMACOLOGY. 2004;p. 209-258
- Thesis / dissertation: 2003
Forskningsbidrag
- Swedish Research Council1 January 2024 - 31 December 2026
- Swedish Cancer Society1 January 2023
- Swedish Research Council1 January 2021 - 31 December 2023
- Barncancerfonden1 January 2021 - 31 December 2021
- Swedish Cancer Society1 January 2020
- Identification of mechanisms regulating tumor development, and generation of next-generation cancer models using cellular reprogrammingSwedish Cancer Society1 January 2019
- Mechanisms controlled by p73 isoforms during tumor developmentSwedish Cancer Society1 January 2018
- Swedish Research Council1 January 2017 - 31 December 2019
- Mechanisms controlled by p73 isoforms during tumor developmentSwedish Cancer Society1 January 2017
- Mechanisms controlled by p73 isoforms during tumor developmentSwedish Cancer Society1 January 2016
- Study on how two different p73 protein variants control tumor development.Swedish Cancer Society1 January 2015
- Study on how two different p73 protein variants control tumor development.Swedish Cancer Society1 January 2014
- Knut and Alice Wallenberg Foundation1 January 2013 - 1 January 2018
- Swedish Research Council1 January 2013 - 31 December 2015
- Swedish Research Council1 January 2011 - 31 December 2014
- Swedish Research Council1 January 2011 - 31 December 2013
- Swedish Research Council1 January 2009 - 31 December 2012
Anställningar
- Senior Forskare, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2022-
Examina och utbildning
- Docent, Tumörbiologi, Karolinska Institutet, 2016
- MEDICINE DOKTORSEXAMEN, Institutionen för onkologi-patologi, Karolinska Institutet, 2003
Uppdrag
- Sektionsansvarig, Division Tumor Biology, Microbiology, Tumor and Cell biology (MTC), Karolinska Institutet, 2024-