Manuel Patarroyo

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: DEVELOPMENT. 2021;148(12):dev199281
Laminin alpha 5 regulates mammary gland remodeling through luminal cell differentiation and Wnt4-mediated epithelial crosstalk
Englund JI; Ritchie A; Blaas L; Cojoc H; Pentinmikko N; Dohla J; Iqbal S; Patarroyo M; Katajisto P
Article: KIDNEY INTERNATIONAL. 2019;96(6):1320-1331
Maternal alloimmune IgG causes anti-glomerular basement membrane disease in perinatal transgenic mice that express human laminin α5
Abrahamson DR; Steenhard BM; Stroganova L; Zelenchuk A; St John PL; Petroff MG; Patarroyo M; Borza DB
Article: MATRIX BIOLOGY. 2018;70:5-19
Culturing functional pancreatic islets on α5-Iaminins and curative transplantation , to diabetic mice
Sigmundsson K; Ojala JRM; Ohman MK; Osterholm A-M; Moreno-Moral A; Domogatskaya A; Chong LY; Sun Y; Chai X; Steele JAM; George B; Patarroyo M; Nilsson A-S; Rodin S; Ghosh S; Stevens MM; Petretto E; Tryggvason K
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2016;14(3):606-618
Tetraspanin CD151 and integrin 61 mediate platelet-enhanced endothelial colony forming cell angiogenesis
Huang Z; Miao X; Patarroyo M; Nilsson GP; Pernow J; Li N
Article: PLOS ONE. 2015;10(4):e0124119
Bacterial Genotoxins Promote Inside-Out Integrin β1 Activation, Formation of Focal Adhesion Complexes and Cell Spreading
Levi L; Toyooka T; Patarroyo M; Frisan T
Article: PLOS ONE. 2015;10(9):e0137419
Mesenchymal Stromal Cells for Sphincter Regeneration: Role of Laminin Isoforms upon Myogenic Differentiation
Seeger T; Hart M; Patarroyo M; Rolauffs B; Aicher WK; Klein G
Article: GENES & DEVELOPMENT. 2015;29(1):1-6
A laminin 511 matrix is regulated by TAZ and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells
Chang C; Goel HL; Gao H; Pursell B; Shultz LD; Greiner DL; Ingerpuu S; Patarroyo M; Cao S; Lim E; Mao J; Mckee KK; Yurchenco PD; Mercurio AM
Article: MATRIX BIOLOGY. 2014;38:69-83
Laminins 411 and 421 differentially promote tumor cell migration via α6β1 integrin and MCAM (CD146)
Ishikawa T; Wondimu Z; Oikawa Y; Gentilcore G; Kiessling R; Brage SE; Hansson J; Patarroyo M
Article: MATRIX BIOLOGY. 2014;36:5-14
7 Monoclonal antibodies to human laminin α4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of α6β1 integrin and MCAM to α4-laminins
Ishikawa T; Wondimu Z; Oikawa Y; Ingerpuu S; Virtanen I; Patarroyo M
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2014;12(4):519-527
Platelets store laminins 411/421 and 511/521 in compartments distinct from α- or dense granules and secrete these proteins via microvesicles
Pook M; Tamming L; Padari K; Tiido T; Maimets T; Patarroyo M; Juronen E; Jaks V; Ingerpuu S
Article: PLOS ONE. 2013;8(1):e53648
A Novel Monoclonal Antibody to Human Laminin α5 Chain Strongly Inhibits Integrin-Mediated Cell Adhesion and Migration on Laminins 511 and 521
Wondimu Z; Omrani S; Ishikawa T; Javed F; Oikawa Y; Virtanen I; Juronen E; Ingerpuu S; Patarroyo M
Article: BIOMEDICAL MATERIALS. 2012;7(3):035011
Integrin-mediated adhesion of human mesenchymal stem cells to extracellular matrix proteins adsorbed to polymer surfaces
Danmark S; Finne-Wistrand A; Albertsson A-C; Patarroyo M; Mustafa K
Article: EXPERIMENTAL CELL RESEARCH. 2011;317(8):1119-1133
Melanoma cells produce multiple laminin isoforms and strongly migrate on α5 laminin(s) via several integrin receptors
Oikawa Y; Hansson J; Sasaki T; Rousselle P; Domogatskaya A; Rodin S; Tryggvason K; Patarroyo M
Article: JOURNAL OF IMMUNOLOGY. 2009;183(7):4657-4665
Human Mast Cells Adhere to and Migrate on Epithelial and Vascular Basement Membrane Laminins LM-332 and LM-511 via α₃β₁ Integrin
Sime W; Lunderius-Andersson C; Enoksson M; Rousselle P; Tryggvason K; Nilsson G; Harvima I; Patarroyo M
Article: MOLECULAR AND CELLULAR NEUROSCIENCE. 2008;39(1):50-62
Integrin-laminin interactions controlling neurite outgrowth from adult DRG neurons in vitro
Plantman S; Patarroyo M; Fried K; Domogatskaya A; Tryggvason K; Hammarberg H; Cullheim S
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2008;84(3):701-712
Laminin isoforms of lymph nodes and predominant role of α5-laminin(s) in adhesion and migration of blood lymphocytes
Gorfu G; Virtanen I; Hukkanen M; Lehto V-P; Rousselle P; Kenne E; Lindbom L; Kramer R; Tryggvason K; Patarroyo M
Article: HISTOCHEMISTRY AND CELL BIOLOGY. 2008;130(3):509-525
Epithelial-mesenchymal transition downregulates laminin α5 chain and upregulates laminin α4 chain in oral squamous carcinoma cells
Takkunen M; Ainola M; Vainionpaa N; Grenman R; Patarroyo M; de Herreros AG; Konttinen YT; Virtanen I
Article: EXPERIMENTAL CELL RESEARCH. 2007;313(18):3819-3831
Laminin isoforms and their integrin receptors in glioma cell migration and invasiveness:: Evidence for a role of α5-laminin(s) and α3β1 integrin
Kawataki T; Yamane T; Naganuma H; Rousselle P; Anduren I; Tryggvason K; Patarroyo M
Article: PHYSIOLOGY & BEHAVIOR. 2007;92(1-2):40-45
Target finding of pain nerve fibers: Neural growth mechanisms in the tooth pulp
Fried K; Lillesaar C; Sime W; Kaukua N; Patarroyo M
Article: MATRIX BIOLOGY. 2006;25(2):89-93
Characterization of commercial laminin preparations from human placenta in comparison to recombinant laminins 2 (α2β1γ1),8 (α4β1γ1),10 (α5β1γ1)
Wondimu Z; Gorfu G; Kawataki T; Smirnov S; Yurchenco P; Tryggvason K; Patarroyo M
Article: THROMBOSIS AND HAEMOSTASIS. 2006;95(1):85-93
Megakaryocytic cells synthesize and platelets secrete α5-laminins, and the endothelial laminin isoform laminin 10 (α5β1γ1) strongly promotes adhesion but not activation of platelets
Nigatu A; Sime W; Gorfu G; Geberhiwot T; Andurén I; Ingerpuu S; Doi M; Tryggvason K; Hjemdahl P; Patarroyo M
Article: EXPERIMENTAL CELL RESEARCH. 2005;307(2):329-341
Laminins 2(α2β1γ1, Lm-211) and 8(α4β1γ1, Lm-411) are synthesized and secreted by tooth pulp fibroblasts and differentially promote neurite outgrowth from trigeminal ganglion sensory neurons
Fried K; Sime W; Lillesaar C; Virtanen I; Tryggvasson K; Patarroyo M
Article: BLOOD. 2004;104(6):1859-1866
An endothelial laminin isoform, laminin 8 (α4β1γ1), is secreted by blood neutrophils, promotes neutrophil migration and extravasation, and protects neutrophils from apoptosis
Wondimu Z; Geberhiwot T; Ingerpuu S; Juronen E; Xie X; Lindbom L; Doi M; Kortesmaa J; Thyboll J; Tryggvason K; Fadeel B; Patarroyo M
Article: JOURNAL OF COMPARATIVE NEUROLOGY. 2002;454(3):284-293
Laminin chains in rat and human peripheral nerve: Distribution and regulation during development and after axonal injury
Wallquist W; Patarroyo M; Thams S; Carlstedt T; Stark B; Cullheim S; Hammarberg H
Article: MATRIX BIOLOGY. 2002;21(6):483-486
Chondroitin sulphate modification in the α4 chain of human recombinant laminin-8 (α4β1γ1)
Kortesmaa J; Doi M; Patarroyo M; Tryggvason K
Article: JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY. 2002;50(8):1113-1130
Localization of laminin α4-chain in developing and adult human tissues
Petäjäniemi N; Korhonen M; Kortesmaa J; Tryggvason K; Sekiguchi K; Fujiwara H; Sorokin L; Thornell LE; Wondimu Z; Assefa D; Patarroyo M; Virtanen I
Article: SEMINARS IN CANCER BIOLOGY. 2002;12(3):197-207
Laminin isoforms in tumor invasion, angiogenesis and metastasis
Patarroyo M; Tryggvason K; Virtanen I
Article: JOURNAL OF CELL SCIENCE. 2001;114(2):423-433
Laminin-8 (α4β1γ1) is synthesized by lymphoid cells, promotes lymphocyte migration and costimulates T cell proliferation
Geberhiwot T; Assefa D; Kortesmaa J; Ingerpuu S; Pedraza C; Wondimu Z; Charo J; Kiessling R; Virtanen I; Tryggvason K; Patarroyo M
Article: JOURNAL OF IMMUNOLOGY. 2000;165(10):5831-5838
Monocytic cells synthesize, adhere to, and migrate on laminin-8 (α₄β₁γ₁)
Pedraza C; Geberhiwot T; Ingerpuu S; Assefa D; Wondimu Z; Kortesmaa J; Tryggvason K; Virtanen I; Patarroyo M
Article: MATRIX BIOLOGY. 2000;19(2):163-167
Chain specificity assignment of monoclonal antibodies to human laminins by using recombinant laminin β1 and γ1 chains
Geberhiwot T; Wondimu Z; Salo S; Pikkarainen T; Kortesmaa J; Tryggvason K; Virtanen I; Patarroyo M
Article: ARTHRITIS & RHEUMATOLOGY. 2000;43(2):336-348
Decreased expression of interleukin-1α, interleukin-1β, and cell adhesion molecules in muscle tissue following corticosteroid treatment in patients with polymyositis and dermatomyositis
Lundberg I; Kratz AK; Alexanderson H; Patarroyo M
Article: EXPERIMENTAL CELL RESEARCH. 2000;254(1):189-195
Erythromegakaryocytic cells synthesize laminin-8 (α4β1γ1)
Geberhiwot T; Ingerpuu S; Pedraza C; Neira M; Virtanen I; Tryggvason K; Patarroyo M
Article: EXPERIMENTAL CELL RESEARCH. 1999;253(2):723-732
Blood platelets contain and secrete laminin-8 (α4β1γ1) and adhere to laminin-8 via α6β1 integrin
Geberhiwot T; Ingerpuu S; Pedraza C; Neira M; Lehto U; Virtanen I; Kortesmaa J; Tryggvason K; Engvall E; Patarroyo M
Article: GASTROENTEROLOGY. 1999;117(3):595-604
Signal transduction-mediated adherence and entry of Helicobacter pylori into cultured cells
Su B; Johansson S; Fällman M; Patarroyo M; Granström M; Normark S
Article: EXPERIMENTAL CELL RESEARCH. 1997;233(1):33-40
Endogenous fibronectin of blood polymorphonuclear leukocytes: Stimulus-induced secretion and proteolysis by cell surface-bound elastase
Salcedo R; Wasserman K; Patarroyo M
Article: EXPERIMENTAL CELL RESEARCH. 1997;233(1):25-32
Endogenous fibronectin of blood polymorphonuclear leukocytes: Immunochemical characterization and subcellular localization
Salcedo R; Segura C; Szekely L; deMesquita R; Biberfeld P; Patarroyo M
Article: JOURNAL OF CELL SCIENCE. 1997;110:1133-1139
Myeloperoxidase mediates cell adhesion via the alpha(M)beta(2) integrin (Mac-1, CD11b/CD18)
Johansson MW; Patarroyo M; Oberg F; Siegbahn A; Nilsson K
Article: CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY. 1997;83(1):68-76
Tumor cell arrest in the microcirculation: Lack of evidence for a leukocyte-like rolling adhesive interaction with vascular endothelium in vivo
Thorlacius H; Prieto J; Raud J; Gautam N; Patarroyo M; Hedqvist P; Lindbom L
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1997;58(1):32-39
Adhesion molecule CD11a/CD18-deficient Burkitt's lymphoma cells lack the transcript for the beta, but not the alpha, integrin subunit
Neira M; Rincon J; Arias H; Law SKA; Patarroyo M
Article: HISTOPATHOLOGY. 1996;29(4):337-346
Expression of adhesion molecules in endemic and epidemic Kaposi's sarcoma
Kaaya EE; CastanosVelez E; Amir H; Lema L; Luande J; Kitinya J; Patarroyo M; Biberfeld P
Article: PARASITE IMMUNOLOGY. 1996;18(5):227-239
Increased expression and secretion of ICAM-1 during experimental infection with Trypanosoma cruzi
Laucella S; Salcedo R; CastanosVelez E; Riarte A; DeTitto EH; Patarroyo M; Orn A; Rottenberg ME
Article: IMMUNOLOGY. 1995;86(2):270-278
EXTRACELLULAR-MATRIX PROTEINS AND INTEGRIN RECEPTORS IN REACTIVE AND NONREACTIVE LYMPH-NODES
CASTANOSVELEZ E; BIBERFELD P; PATARROYO M
Article: INFECTION AND IMMUNITY. 1995;63(10):4054-4062
ESCHERICHIA-COLI INDUCES TRANSUROEPITHELIAL NEUTROPHIL MIGRATION BY AN INTERCELLULAR-ADHESION MOLECULE-1-DEPENDENT MECHANISM
AGACE WW; PATARROYO M; SVENSSON M; CARLEMALM E; SVANBORG C
Article: CELLULAR IMMUNOLOGY. 1995;160(2):165-172
CONSTITUTIVE ALPHA-V-BETA-3 INTEGRIN-MEDIATED ADHESION OF HUMAN LYMPHOID B-CELLS TO VITRONECTIN SUBSTRATE
SALCEDO R; PATARROYO M
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Alla övriga publikationer

Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2019;185(1):179-183
HAX-1 overexpression in multiple myeloma is associated with poor survival
Feng X; Kwiecinska A; Rossmann E; Bottai M; Ishikawa T; Patarroyo M; Osterborg A; Porwit A; Zheng C; Fadeel B
Review: MATRIX BIOLOGY. 2005;24(5):326-332
A simplified laminin nomenclature
Aumailley M; Bruckner-Tuderman L; Carter WG; Deutzmann R; Edgar D; Ekblom P; Engel J; Engvall E; Hohenester E; Jones JCR; Kleinman HK; Marinkovich MP; Martin GR; Mayer U; Meneguzzi G; Miner JH; Miyazaki K; Patarroyo M; Paulsson M; Quaranta V; Sanes JR; Sasaki T; Sekiguchi K; Sorokin LM; Talts JF; Tryggvason K; Uitto J; Virtanen I; von der Mark K; Wewer UM; Yamada Y; Yurchenco PD
Meeting abstract: GASTROENTEROLOGY. 1998;114(4):A1092
Phosphotyrosine signaling is required for adherence of H-pylori to cultured gastric cells:: H-pylori interaction with gastric cells using Yersinia as a tool.
Su B; Patarroyo M; Granström M; Normark S

Anställningar

Professor Emeritus/Emerita, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2025-2028
Professor, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2016-2025

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