Magnus Olsson

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Magnus Olsson erhöll sin doktorsexamen i molekylär cellbiologi från Prof. Peter Ekbloms laboratorium vid Lunds universitet 2003. 2004 blev han post doktor i Prof. Zhivotovskys laboratorium vid Karolinska Institutet. Från 2008 till 2023 arbetade han som Senior Research Specialist på Institutet för miljömedicin (IMM) och bedrev forskning inom områdena programmerad celldöd och redoxbiologi. Magnus blev docent i toxikologi vid KI 2017.

Forskningsbeskrivning

- Kartläggning av faktorer som utsöndras under förloppet programmerad celldöd (PCD).
- Sambandet mellan fettsyrametabolism och neurondifferentiering, särskilt med avseende på den blockeringen i cellspecialisering som kan resultera i neuroblastom.

Undervisning

Kursansvarig på masterprogrammet i toxikologi, kandidatprogrammet i biomedicin och röntgenprogrammet. För närvarande bihandledare för en doktorand. Tidigare huvudhandledare för två doktorander och bihandledare för två doktorander.

Artiklar

Article: NEURO-ONCOLOGY. 2024;26(9):1685-1699
High-throughput neural stem cell-based drug screening identifies S6K1 inhibition as a selective vulnerability in sonic hedgehog-medulloblastoma
Zhou L; van Bree N; Boutin L; Ryu J; Moussaud S; Liu M; Otrocka M; Olsson M; Falk A; Wilhelm M
Journal article: TOXICOLOGY LETTERS. 2024;399:s364
Hexagonal boron nitride (hBN) and hBN-reinforced thermoplastic polyurethane composite: an in vitro hazard characterization using human skin and lung cells
Carlin M; Kaur J; Ciobanu DZ; Song Z; Olsson M; Totu T; Gupta G; Peng G; Jehova Gonzalez V; Janica IJ; Pozo VF; Chortarea S; Buljan M; Buerki-Thurnherr T; Castillo AEDR; Thorat S; Bonaccorso F; Tubaro A; Vazquez E; Prato M; Armirotti A; Wick P; Bianco A; Fadeel B; Pelin M
Article: JOURNAL OF HAZARDOUS MATERIALS. 2024;473:134686
Hazard assessment of hexagonal boron nitride and hexagonal boron nitride reinforced thermoplastic polyurethane composites using human skin and lung cells
Carlin M; Kaur J; Ciobanu DZ; Song Z; Olsson M; Totu T; Gupta G; Peng G; Gonzalez VJ; Janica I; Pozo VF; Chortarea S; Buljan M; Buerki-Thurnherr T; Castillo AEDR; Thorat SB; Bonaccorso F; Tubaro A; Vazquez E; Prato M; Armirotti A; Wick P; Bianco A; Fadeel B; Pelin M
Article: PHARMACOLOGICAL RESEARCH. 2023;196:106899
Microsomal glutathione transferase 1 controls metastasis and therapeutic response in melanoma
Zhang J; Ye Z-W; Chakraborty P; Luo Z; Culpepper J; Aslam M; Zhang L; Johansson K; Haeggstrom JZ; Xu J; Olsson M; Townsend DM; Mehrotra S; Morgenstern R; Tew KD
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2023;299(8):104920
A role for microsomal glutathione transferase 1 in melanin biosynthesis and melanoma progression
Zhang J; Ye Z-W; Braeutigam L; Chakraborty P; Luo Z; Culpepper J; Aslam M; Zhang L; Johansson K; Haeggstrom JZ; Xu J; Olsson M; Townsend DM; Mehrotra S; Morgenstern R; Tew KD
Article: CELL DEATH DISCOVERY. 2022;8(1):284
Caspase-2 is a mediator of apoptotic signaling in response to gemtuzumab ozogamicin in acute myeloid leukemia
Haag P; Olsson M; Forsberg J; Lindberg ML; Stenerlow B; Zong D; Kanter L; Lewensohn R; Viktorsson K; Zhivotovsky B; Stenke L
Article: ANALYTICAL SCIENCE ADVANCES. 2021;2(5-6):263-271
Determining site occupancy of acetaminophen covalent binding to target proteins in vitro
Geib T; Lento C; Marensi V; Thulasingam M; Haeggstrom JZ; Olsson M; Wilson DJ; Leslie EM; Sleno L
Article: NANOIMPACT. 2021;22:100313
Pulmonary toxicity and gene expression changes after short-term inhalation exposure to surface-modified copper oxide nanoparticles
Gosens I; Costa PM; Olsson M; Stone V; Costa AL; Brunelli A; Badetti E; Bonetto A; Bokkers BGH; de Jong WH; Williams A; Halappanavar S; Fadeel B; Cassee FR
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2018;499(4):822-828
Caspase-2 associates with FAN through direct interaction and overlapping functionality
Forsberg J; Li X; Zamaraev AV; Panaretakis T; Zhivotovsky B; Olsson M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(18):4731-4736
O⁶-methylguanine-induced transcriptional mutagenesis reduces p53 tumor-suppressor function
Ezerskyte M; Paredes JA; Malvezzi S; Burns JA; Margison GP; Olsson M; Scicchitano DA; Dreij K
Article: CHEMOSPHERE. 2018;196:482-493
Toxicity of surface-modified copper oxide nanoparticles in a mouse macrophage cell line: Interplay of particles, surface coating and particle dissolution
Libalova H; Costa PM; Olsson M; Farcal L; Ortelli S; Blosi M; Topinka J; Costa AL; Fadeel B
Article: CELL DEATH AND DISEASE. 2018;9(2):80
A caspase-2-RFXANK interaction and its implication for MHC class II expression
Forsberg J; Li X; Akpinar B; Salvatori R; Ott M; Zhivotovsky B; Olsson M
Article: BLOOD. 2016;128(23):2655-2665
Caspase-3-dependent cleavage of Bcl-xL in the stroma exosomes is required for their uptake by hematological malignant cells
Vardaki I; Sanchez C; Fonseca P; Olsson M; Chioureas D; Rassidakis G; Ullen A; Zhivotovsky B; Bjorkholm M; Panaretakis T
Journal article: ONCOTARGET. 2016;7(44):72380
5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53 (vol 6, pg 43679, 2015)
Akpinar B; Bracht EV; Reijnders D; Safarikova B; Jelinkova I; Grandien A; Vaculova AH; Zhivotovsky B; Olsson M
Article: ONCOTARGET. 2016;7(36):58286-58301
Aberrant DR5 transport through disruption of lysosomal function suggests a novel mechanism for receptor activation
Akpinar B; Safarikova B; Laukova J; Debnath S; Vaculova AH; Zhivotovsky B; Olsson M
Article: ONCOTARGET. 2015;6(41):43679-43697
5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53
Akpinar B; Bracht EV; Reijnders D; Safarikova B; Jelinkova I; Grandien A; Vaculova AH; Zhivotovsky B; Olsson M
Article: METHODS IN MOLECULAR BIOLOGY. 2014;1133:155-173
Measurement of caspase activation in mammalian cell cultures.
Olsson M; Zhivotovsky B
Article: CELL DEATH AND DISEASE. 2013;4(12):e940
Caspase-2 promotes cytoskeleton protein degradation during apoptotic cell death
Vakifahmetoglu-Norberg H; Norberg E; Perdomo AB; Olsson M; Ciccosanti F; Orrenius S; Fimia GM; Piacentini M; Zhivotovsky B
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2013;1833(10):2279-2292
Determining the contributions of caspase-2, caspase-8 and effector caspases to intracellular VDVADase activities during apoptosis initiation and execution
Delgado ME; Olsson M; Lincoln FA; Zhivotovsky B; Rehm M
Article: ONCOGENE. 2013;32(38):4529-4538
5-Fluorouracil signaling through a calcium-calmodulin-dependent pathway is required for p53 activation and apoptosis in colon carcinoma cells
Can G; Akpinar B; Baran Y; Zhivotovsky B; Olsson M
Article: ONCOGENE. 2009;28(18):1949-1959
DISC-mediated activation of caspase-2 in DNA damage-induced apoptosis
Olsson M; Vakifahmetoglu H; Abruzzo PM; Hogstrand K; Grandien A; Zhivotovsky B
Article: CELL DEATH AND DIFFERENTIATION. 2008;15(3):555-566
DNA damage induces two distinct modes of cell death in ovarian carcinomas
Vakifahmetoglu H; Olsson M; Tamm C; Heidari N; Orrenius S; Zhivotovsky B
Article: ONCOGENE. 2006;25(41):5683-5692
Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage
Vakifahmetoglu H; Olsson M; Orrenius S; Zhivotovsky B
Article: JOURNAL OF NEGATIVE RESULTS IN BIOMEDICINE. 2004;3:7
Despite WT1 binding sites in the promoter region of human and mouse nucleoporin glycoprotein 210, WT1 does not influence expression of GP210.
Olsson M; English MA; Mason J; Licht JD; Ekblom P
Article: EXPERIMENTAL CELL RESEARCH. 2004;292(2):359-370
Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans
Olsson M; Schéele S; Ekblom P
Article: EXPERIMENTAL CELL RESEARCH. 2002;279(2):188-201
Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens
Salmivirta K; Talts JF; Olsson M; Sasaki T; Timpl R; Ekblom P
Article: CELL AND TISSUE RESEARCH. 2002;308(3):361-370
Nulp1, a novel basic helix-loop-helix protein expressed broadly during early embryonic organogenesis and prominently in developing dorsal root ganglia
Olsson M; Durbeej M; Ekblom P; Hjalt T
Article: CELL AND TISSUE RESEARCH. 2000;300(1):129-137
Differential expression of mouse laminin γ2 and γ2*chain transcripts
Airenne T; Lin YF; Olsson M; Ekblom P; Vainio S; Tryggvason K
Article: KIDNEY INTERNATIONAL. 1999;56(3):827-838
CDNA cloning and embryonic expression of mouse nuclear pore membrane glycoprotein 210 mRNA
Olsson M; Ekblom M; Fecker L; Kurkinen M; Ekblom P
Article: GENE THERAPY. 1997;4(10):1093-1099
Efficient adenovirus-mediated gene transduction of normal and leukemic hematopoietic cells
Huang MR; Olsson M; Kallin A; Pettersson U; Totterman TH
Visa fler

Alla övriga publikationer

Review: ONCOGENE. 2017;36(39):5441-5444
Caspase-2: an orphan enzyme out of the shadows
Forsberg J; Zhivotovsky B; Olsson M
Corrigendum: ONCOTARGET. 2016;7(19):28761-28762
Correction: 5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53.
Akpinar B; Bracht EV; Reijnders D; Safarikova B; Jelinkova I; Grandien A; Hyrslova Vaculova A; Zhivotovsky B; Olsson M
Review: ONCOGENE. 2015;34(15):1877-1882
Caspase-2: the reinvented enzyme
Olsson M; Forsberg J; Zhivotovsky B
Review: CELL DEATH AND DIFFERENTIATION. 2011;18(9):1441-1449
Caspases and cancer
Olsson M; Zhivotovsky B
Review: CELL DEATH AND DIFFERENTIATION. 2008;15(7):1153-1162
Death through a tragedy: mitotic catastrophe
Vakifahmetoglu H; Olsson M; Zhivotovsky B
Conference publication: BIOCHIMICA ET BIOPHYSICA ACTA - BIOENERGETICS. 2006;:63
Nuclei-mitochondria cross-talk in apoptosis
Zhivotovsky B; Vakifahmetoglu H; Olsson M; Gogvadze V; Orrenius S
Thesis / dissertation: 2003
Nuclear pore membrane glycoprotein 210 as a new marker for epithelial cells
Olsson M
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 1999;113(6):1139
Differential expression of mouse laminin γ2 and γ2*chain transcripts
Airenne T; Lin YF; Olsson M; Ekblom P; Vainio S; Tryggvason K

Anställningar

Adjunkt, Klinisk vetenskap, intervention och teknik, Karolinska Institutet, 2023-

Examina och utbildning

Docent, Toxikologi, Karolinska Institutet, 2017

Om mig

Forskningsbeskrivning

Undervisning

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI