Magnus Olsson

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Magnus Olsson erhöll sin doktorsexamen i molekylär cellbiologi från Prof. Peter Ekbloms laboratorium vid Lunds universitet 2003. 2004 blev han post doktor i Prof. Zhivotovskys laboratorium vid Karolinska Institutet. Från 2008 till 2023 arbetade han som Senior Research Specialist på Institutet för miljömedicin (IMM) och bedrev forskning inom områdena programmerad celldöd och redoxbiologi. Magnus blev docent i toxikologi vid KI 2017.

Forskningsbeskrivning

- Kartläggning av faktorer som utsöndras under förloppet programmerad celldöd (PCD).
- Sambandet mellan fettsyrametabolism och neurondifferentiering, särskilt med avseende på den blockeringen i cellspecialisering som kan resultera i neuroblastom.

Undervisning

Kursansvarig på masterprogrammet i toxikologi, kandidatprogrammet i biomedicin och röntgenprogrammet. För närvarande bihandledare för en doktorand. Tidigare huvudhandledare för två doktorander och bihandledare för två doktorander.

Artiklar

Journal article: JOURNAL OF HAZARDOUS MATERIALS. 2024;473:134686

Hazard assessment of hexagonal boron nitride and hexagonal boron nitride reinforced thermoplastic polyurethane composites using human skin and lung cells.

Carlin M; Kaur J; Ciobanu DZ; Song Z; Olsson M; Totu T; Gupta G; Peng G; González VJ; Janica I; Pozo VF; Chortarea S; Buljan M; Buerki-Thurnherr T; Rio Castillo AED; Thorat SB; Bonaccorso F; Tubaro A; Vazquez E; Prato M; Armirotti A; Wick P; Bianco A; Fadeel B; Pelin M
Journal article: NEURO-ONCOLOGY. 2024;:noae104

High-throughput neural stem cell-based drug screening identifies S6K1 inhibition as a selective vulnerability in SHH-medulloblastoma.

Zhou L; van Bree N; Boutin L; Ryu J; Moussaud S; Liu M; Otrocka M; Olsson M; Falk A; Wilhelm M
Article: PHARMACOLOGICAL RESEARCH. 2023;196:106899

Microsomal glutathione transferase 1 controls metastasis and therapeutic response in melanoma.

Zhang J; Ye Z-W; Chakraborty P; Luo Z; Culpepper J; Aslam M; Zhang L; Johansson K; Haeggström JZ; Xu J; Olsson M; Townsend DM; Mehrotra S; Morgenstern R; Tew KD
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2023;299(8):104920

A role for microsomal glutathione transferase 1 in melanin biosynthesis and melanoma progression.

Zhang J; Ye Z-W; Bräutigam L; Chakraborty P; Luo Z; Culpepper J; Aslam M; Zhang L; Johansson K; Haeggström JZ; Xu J; Olsson M; Townsend DM; Mehrotra S; Morgenstern R; Tew KD
Article: CELL DEATH DISCOVERY. 2022;8(1):284

Caspase-2 is a mediator of apoptotic signaling in response to gemtuzumab ozogamicin in acute myeloid leukemia.

Hååg P; Olsson M; Forsberg J; Lindberg ML; Stenerlöw B; Zong D; Kanter L; Lewensohn R; Viktorsson K; Zhivotovsky B; Stenke L
Article: ANAL SCI ADV. 2021;2(5-6):263-271

Determining site occupancy of acetaminophen covalent binding to target proteins in vitro.

Geib T; Lento C; Marensi V; Thulasingam M; Haeggström JZ; Olsson M; Wilson DJ; Leslie EM; Sleno L
Article: NANOIMPACT. 2021;22:100313

Pulmonary toxicity and gene expression changes after short-term inhalation exposure to surface-modified copper oxide nanoparticles.

Gosens I; Costa PM; Olsson M; Stone V; Costa AL; Brunelli A; Badetti E; Bonetto A; Bokkers BGH; de Jong WH; Williams A; Halappanavar S; Fadeel B; Cassee FR
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2018;499(4):822-828

Caspase-2 associates with FAN through direct interaction and overlapping functionality.

Forsberg J; Li X; Zamaraev AV; Panaretakis T; Zhivotovsky B; Olsson M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(18):4731-4736

O6-methylguanine-induced transcriptional mutagenesis reduces p53 tumor-suppressor function.

Ezerskyte M; Paredes JA; Malvezzi S; Burns JA; Margison GP; Olsson M; Scicchitano DA; Dreij K
Article: CHEMOSPHERE. 2018;196:482-493

Toxicity of surface-modified copper oxide nanoparticles in a mouse macrophage cell line: Interplay of particles, surface coating and particle dissolution.

Líbalová H; Costa PM; Olsson M; Farcal L; Ortelli S; Blosi M; Topinka J; Costa AL; Fadeel B
Article: CELL DEATH & DISEASE. 2018;9(2):80

A caspase-2-RFXANK interaction and its implication for MHC class II expression.

Forsberg J; Li X; Akpinar B; Salvatori R; Ott M; Zhivotovsky B; Olsson M
Article: BLOOD. 2016;128(23):2655-2665

Caspase-3-dependent cleavage of Bcl-xL in the stroma exosomes is required for their uptake by hematological malignant cells.

Vardaki I; Sanchez C; Fonseca P; Olsson M; Chioureas D; Rassidakis G; Ullén A; Zhivotovsky B; Björkholm M; Panaretakis T
Journal article: ONCOTARGET. 2016;7(44):72380

Correction: 5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53.

Akpinar B; Bracht EV; Reijnders D; Safarikova B; Jelinkova I; Grandien A; Vaculova AH; Zhivotovsky B; Olsson M
Article: ONCOTARGET. 2016;7(36):58286-58301

Aberrant DR5 transport through disruption of lysosomal function suggests a novel mechanism for receptor activation.

Akpinar B; Safarikova B; Laukova J; Debnath S; Vaculova AH; Zhivotovsky B; Olsson M
Article: ONCOTARGET. 2015;6(41):43679-43697

5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53.

Akpinar B; Bracht EV; Reijnders D; Safarikova B; Jelinkova I; Grandien A; Vaculova AH; Zhivotovsky B; Olsson M
Article: METHODS IN MOLECULAR BIOLOGY. 2014;1133:155-173

Measurement of caspase activation in mammalian cell cultures.

Olsson M; Zhivotovsky B
Article: CELL DEATH & DISEASE. 2013;4(12):e940

Caspase-2 promotes cytoskeleton protein degradation during apoptotic cell death.

Vakifahmetoglu-Norberg H; Norberg E; Perdomo AB; Olsson M; Ciccosanti F; Orrenius S; Fimia GM; Piacentini M; Zhivotovsky B
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2013;1833(10):2279-2292

Determining the contributions of caspase-2, caspase-8 and effector caspases to intracellular VDVADase activities during apoptosis initiation and execution.

Delgado ME; Olsson M; Lincoln FA; Zhivotovsky B; Rehm M
Article: ONCOGENE. 2013;32(38):4529-4538

5-Fluorouracil signaling through a calcium-calmodulin-dependent pathway is required for p53 activation and apoptosis in colon carcinoma cells.

Can G; Akpinar B; Baran Y; Zhivotovsky B; Olsson M
Article: ONCOGENE. 2009;28(18):1949-1959

DISC-mediated activation of caspase-2 in DNA damage-induced apoptosis.

Olsson M; Vakifahmetoglu H; Abruzzo PM; Högstrand K; Grandien A; Zhivotovsky B
Article: CELL DEATH AND DIFFERENTIATION. 2008;15(3):555-566

DNA damage induces two distinct modes of cell death in ovarian carcinomas.

Vakifahmetoglu H; Olsson M; Tamm C; Heidari N; Orrenius S; Zhivotovsky B
Article: ONCOGENE. 2006;25(41):5683-5692

Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage.

Vakifahmetoglu H; Olsson M; Orrenius S; Zhivotovsky B
Article: JOURNAL OF NEGATIVE RESULTS IN BIOMEDICINE. 2004;3:7

Despite WT1 binding sites in the promoter region of human and mouse nucleoporin glycoprotein 210, WT1 does not influence expression of GP210.

Olsson M; English MA; Mason J; Licht JD; Ekblom P
Article: EXPERIMENTAL CELL RESEARCH. 2004;292(2):359-370

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

Olsson M; Schéele S; Ekblom P
Article: EXPERIMENTAL CELL RESEARCH. 2002;279(2):188-201

Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens.

Salmivirta K; Talts JF; Olsson M; Sasaki T; Timpl R; Ekblom P
Article: CELL AND TISSUE RESEARCH. 2002;308(3):361-370

Nulp1, a novel basic helix-loop-helix protein expressed broadly during early embryonic organogenesis and prominently in developing dorsal root ganglia.

Olsson M; Durbeej M; Ekblom P; Hjalt T
Article: CELL AND TISSUE RESEARCH. 2000;300(1):129-137

Differential expression of mouse laminin gamma2 and gamma2* chain transcripts.

Airenne T; Lin Y; Olsson M; Ekblom P; Vainio S; Tryggvason K
Article: KIDNEY INTERNATIONAL. 1999;56(3):827-838

cDNA cloning and embryonic expression of mouse nuclear pore membrane glycoprotein 210 mRNA.

Olsson M; Ekblom M; Fecker L; Kurkinen M; Ekblom P
Article: GENE THERAPY. 1997;4(10):1093-1099

Efficient adenovirus-mediated gene transduction of normal and leukemic hematopoietic cells.

Huang MR; Olsson M; Kallin A; Pettersson U; Tötterman TH
Visa fler

Alla övriga publikationer

Review: ONCOGENE. 2017;36(39):5441-5444

Caspase-2: an orphan enzyme out of the shadows.

Forsberg J; Zhivotovsky B; Olsson M
Corrigendum: ONCOTARGET. 2016;7(19):28761-28762

Correction: 5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53.

Akpinar B; Bracht EV; Reijnders D; Safarikova B; Jelinkova I; Grandien A; Hyrslova Vaculova A; Zhivotovsky B; Olsson M
Review: ONCOGENE. 2015;34(15):1877-1882

Caspase-2: the reinvented enzyme.

Olsson M; Forsberg J; Zhivotovsky B
Review: CELL DEATH AND DIFFERENTIATION. 2011;18(9):1441-1449

Caspases and cancer.

Olsson M; Zhivotovsky B
Review: CELL DEATH AND DIFFERENTIATION. 2008;15(7):1153-1162

Death through a tragedy: mitotic catastrophe.

Vakifahmetoglu H; Olsson M; Zhivotovsky B
Conference publication: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. 2006;:63

Nuclei-mitochondria cross-talk in apoptosis

Zhivotovsky B; Vakifahmetoglu H; Olsson M; Gogvadze V; Orrenius S
Thesis / dissertation: 2003

Nuclear pore membrane glycoprotein 210 as a new marker for epithelial cells

Olsson M
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 1999;113(6):1139

Differential expression of mouse laminin γ2 and γ2*chain transcripts

Airenne T; Lin YF; Olsson M; Ekblom P; Vainio S; Tryggvason K

Anställningar

Adjunkt, Klinisk vetenskap, intervention och teknik, Karolinska Institutet, 2023-

Examina och utbildning

Docent, Toxikologi, Karolinska Institutet, 2017

Om mig

Forskningsbeskrivning

Undervisning

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI