Magdalena Scharf

Publikationer
Forskningsbidrag
Populärvetenskap och samverkan

Artiklar

Article: MOLECULAR PHARMACOLOGY. 2023;104(3):80-91
EP4 Receptor Conformation Sensor Suited for Ligand Screening and Imaging of Extracellular Prostaglandins
Kurz M; Ulrich M; Bittner A; Scharf MM; Shao J; Wallenstein I; Lemoine H; Wettschureck N; Kolb P; Buenemann M
Article: NATURE COMMUNICATIONS. 2023;14(1):4573
Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformations
Gratz L; Kowalski-Jahn M; Scharf MM; Kozielewicz P; Jahn M; Bous J; Lambert NA; Gloriam DE; Schulte G
Article: ACS PHARMACOLOGY AND TRANSLATIONAL SCIENCE. 2023;6(1):195-199
Viewpoint on the Second Transatlantic GPCR Symposium for Early Career Investigators
Janetzko J; Johnson CP; Morales P; Scharf MM
Article: MOLECULES. 2021;26(3):629
Analyzing Kinase Similarity in Small Molecule and Protein Structural Space to Explore the Limits of Multi-Target Screening
Schmidt D; Scharf MM; Sydow D; Assmann E; Marti-Solano M; Keul M; Volkamer A; Kolb P
Article: CHEMMEDCHEM. 2020;15(10):882-890
A Focus on Unusual ECL2 Interactions Yields β₂-Adrenergic Receptor Antagonists with Unprecedented Scaffolds
Scharf MM; Zimmermann M; Wilhelm F; Stroe R; Waldhoer M; Kolb P
Article: MOLECULAR PHARMACOLOGY. 2019;96(6):851-861
Comparative Docking to Distinct G Protein-Coupled Receptor Conformations Exclusively Yields Ligands with Agonist Efficacy
Scharf MM; Bunemann M; Baker JG; Kolb P
Journal article: FLUID PHASE EQUILIBRIA. 2017;451:48-56
Solvation by aqueous solutions of imidazole-based ionic liquids: 2-A comparison between alkyl and alkoxy side-chains
de Jesus JC; Pires PAR; Scharf M; El Seoud OA

Alla övriga publikationer

Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2024;45(5):419-429
Frizzleds act as dynamic pharmacological entities
Schulte G; Scharf MM; Bous J; Voss JH; Gratz L; Kozielewicz P
Preprint: RESEARCH SQUARE. 2024
SAG1.3-derived Frizzled-targeting negative allosteric modulators
Schulte G; Grätz L; Turku A; Kozielewicz P; Bowin C-F; Scharf M; Voss J; Kinsolving J; Shekhani R; Oliva-Vilarnau N; Koolmeister T; Körber M; Lauschke V; Löber S; Gmeiner P
Review: BRITISH JOURNAL OF PHARMACOLOGY. 2024
The dark sides of the GPCR tree - research progress on understudied GPCRs
Scharf MM; Humphrys LJ; Berndt S; Di Pizio A; Lehmann J; Liebscher I; Nicoli A; Niv MY; Peri L; Schihada H; Schulte G
Editorial comment: FRONTIERS IN ENDOCRINOLOGY. 2023;14:1272700
Editorial: New approaches for the discovery of GPCR ligands
Morales P; Scharf MM; Johnson CP; Di Pizio A; Hilger D

Forskningsbidrag

In silico prediction of small molecule ligands for class Frizzled GPCRs and investigation of the structural basis of FZD signalling
Deutsche Forschungsgemeinschaft
1 January 2021 - 31 December 2024

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