Magdalena Scharf
Postdoctoral Researcher
E-mail: magdalena.scharf@ki.se
Visiting address: Solnavägen 9, Biomedicum, 17165 Solna
Postal address: C3 Fysiologi och farmakologi, C3 FyFa Receptorbiologi, 171 77 Stockholm
About me
- Originally, I am a chemist and obtained my Master of Science in Chemistry in
2016 at the Philipps University Marburg in Germany. In 2017 I then joined the
lab of Peter Kolb at the Institute of Pharmaceutical Chemistry, Philipps
University Marburg, to pursue a PhD. During my work I was mainly (but not
exclusively) focusing on class A G protein-coupled receptors (GPCRs) and
using tools such as Molecular Docking to predict novel ligands with certain
properties for these receptors. In January 2021 I successfully defended my
PhD (Dr. rer. nat.). In September 2021 I joined the lab of Gunnar Schulte as
a postdoctoral researcher to work with the exciting class F GPCRs.
Research
- I am excited about the structural details of GPCR signalling, especially
ligand-receptor interactions but also effector-receptor interactions. During
my work I mainly employ computational tools such as Molecular Docking and
Molecular Dynamics Simulations. However, I am also happy to go to the wet lab
and join the pharmacological characterisation of any hypotheses.
Articles
- Article: MOLECULAR PHARMACOLOGY. 2023;104(3):80-91
- Article: NATURE COMMUNICATIONS. 2023;14(1):4573
- Article: ACS PHARMACOLOGY AND TRANSLATIONAL SCIENCE. 2023;6(1):195-199
- Article: MOLECULES. 2021;26(3):629
- Article: CHEMMEDCHEM. 2020;15(10):882-890
- Article: MOLECULAR PHARMACOLOGY. 2019;96(6):851-861
- Journal article: FLUID PHASE EQUILIBRIA. 2017;451:48-56
All other publications
- Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2024;45(5):419-429
- Preprint: RESEARCH SQUARE. 2024
- Review: BRITISH JOURNAL OF PHARMACOLOGY. 2024
- Editorial comment: FRONTIERS IN ENDOCRINOLOGY. 2023;14:1272700
Grants
- Deutsche Forschungsgemeinschaft1 January 2021 - 31 December 2024