Magdalena Scharf
Postdoctoral Researcher
E-mail: magdalena.scharf@ki.se
Visiting address: Solnavägen 9, Biomedicum, 17165 Solna
Postal address: C3 Fysiologi och farmakologi, C3 FyFa Receptorbiologi, 171 77 Stockholm
About me
- Originally, I am a chemist and obtained my Master of Science in Chemistry in
2016 at the Philipps University Marburg in Germany. In 2017 I then joined the
lab of Peter Kolb at the Institute of Pharmaceutical Chemistry, Philipps
University Marburg, to pursue a PhD. During my work I was mainly (but not
exclusively) focusing on class A G protein-coupled receptors (GPCRs) and
using tools such as Molecular Docking to predict novel ligands with certain
properties for these receptors. In January 2021 I successfully defended my
PhD (Dr. rer. nat.). In September 2021 I joined the lab of Gunnar Schulte as
a postdoctoral researcher to work with the exciting class F GPCRs.
Research
- I am excited about the structural details of GPCR signalling, especially
ligand-receptor interactions but also effector-receptor interactions. During
my work I mainly employ computational tools such as Molecular Docking and
Molecular Dynamics Simulations. However, I am also happy to go to the wet lab
and join the pharmacological characterisation of any hypotheses.
Articles
- Article: NATURE COMMUNICATIONS. 2024;15(1):7422Bous J; Kinsolving J; Gratz L; Scharf MM; Voss JH; Selcuk B; Adebali O; Schulte G
- Article: MOLECULAR PHARMACOLOGY. 2023;104(3):80-91Kurz M; Ulrich M; Bittner A; Scharf MM; Shao J; Wallenstein I; Lemoine H; Wettschureck N; Kolb P; Buenemann M
- Journal article: FRONTIERS IN ENDOCRINOLOGY. 2023;14:1272700Morales P; Scharf MM; Johnson CP; Di Pizio A; Hilger D
- Article: NATURE COMMUNICATIONS. 2023;14(1):4573Gratz L; Kowalski-Jahn M; Scharf MM; Kozielewicz P; Jahn M; Bous J; Lambert NA; Gloriam DE; Schulte G
- Article: ACS PHARMACOLOGY AND TRANSLATIONAL SCIENCE. 2023;6(1):195-199Janetzko J; Johnson CP; Morales P; Scharf MM
- Article: MOLECULES. 2021;26(3):629Schmidt D; Scharf MM; Sydow D; Assmann E; Marti-Solano M; Keul M; Volkamer A; Kolb P
- Article: CHEMMEDCHEM. 2020;15(10):882-890Scharf MM; Zimmermann M; Wilhelm F; Stroe R; Waldhoer M; Kolb P
- Article: MOLECULAR PHARMACOLOGY. 2019;96(6):851-861Scharf MM; Bunemann M; Baker JG; Kolb P
- Journal article: FLUID PHASE EQUILIBRIA. 2017;451:48-56de Jesus JC; Pires PAR; Scharf M; El Seoud OA
All other publications
- Review: BRITISH JOURNAL OF PHARMACOLOGY. 2025;182(14):3109-3134Scharf MM; Humphrys LJ; Berndt S; Di Pizio A; Lehmann J; Liebscher I; Nicoli A; Niv MY; Peri L; Schihada H; Schulte G
- Review: BRITISH JOURNAL OF PHARMACOLOGY. 2025;182(14):3249-3300Morales P; Scharf MM; Bermudez M; Egyed A; Franco R; Hansen OK; Jagerovic N; Jakubik J; Keseru GM; Kiss DJ; Kozielewicz P; Larsen O; Majellaro M; Mallo-Abreu A; Navarro G; Prieto-Diaz R; Rosenkilde MM; Sotelo E; Stark H; Werner T; Wingler LM
- Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2024;45(5):419-429Schulte G; Scharf MM; Bous J; Voss JH; Gratz L; Kozielewicz P
- Preprint: RESEARCH SQUARE. 2024Schulte G; Grätz L; Turku A; Kozielewicz P; Bowin C-F; Scharf M; Voss J; Kinsolving J; Shekhani R; Oliva-Vilarnau N; Koolmeister T; Körber M; Lauschke V; Löber S; Gmeiner P
Grants
- Deutsche Forschungsgemeinschaft1 January 2021 - 31 December 2024