Luana Naia

Luana Naia

Biträdande Lektor
E-postadress: luana.naia@ki.se
Besöksadress: Blickagången 6, 14157 Huddinge
Postadress: H1 Neurobiologi, vårdvetenskap och samhälle, H1 Neurogeriatrik Ankarcrona, 171 77 Stockholm
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Om mig

  • My scientific career has been grounded on studying mitochondrial function, dynamics and mitotherapeutics with potential to reach clinical studies. I 


  • received my PhD in neuroscience and health sciences in 2017 from Faculty of Medicine, University of Coimbra, Portugal. My post-doctoral work was focused on the study of mitochondria-endoplasmic reticulum contact sites (MERCS) in neurodegeneration and drug discovery to modulate MERCS. In 2023, I was appointed as Assistant Professor at Karolinska Institutet where I develop my research line which is focused on neuron-astrocyte mitochondrial communication with a focus on Alzheimer´s Disease.

Forskningsbeskrivning

  • ´ Mitochondria are the clandestine rulers of our world`
    My research is focused on mitochondrial function, dynamics, and organelle interplay (mitochondria associated membranes) in neurodegeneration. My current projects intend to explore the mechanisms underlying mitochondrial dynamics dysfunction and their contribution for bioenergetic dysregulation in Alzheimer´s disease. We are particularly interested in studying mitochondria fission, and transfer between neurons and glia cells, with a special focus on the transfer mediated by mitochondrial-derived extracellular vesicles – mitovesicles. We further aim to explore the potential of mitovesicles as a therapeutical strategy and/or biomarker for disease progression.

Undervisning

  • 2022-present: Coordinating and lecturing the PhD course Alzheimer’s disease: clinical features and pathogenic mechanisms (Karolinska Institutet)
    2019-present: Teaching Cell death mechanisms in the PhD course Protein Mechanisms in Health and Disease, from the Clinical Research School in Molecular Medicine (Karolinska Institutet)
    2018-present: Teaching Mechanisms of Neurodegeneration in the Master programme in Biomedicine (Karolinska Institutet)

Artiklar

Alla övriga publikationer

Forskningsbidrag

  • Start-up grant
    StratNeuro
    15 April 2024 - 15 April 2026
  • Mitovesiklar: en ny strategi för att förstå och lindra neurodegeneration av Alzheimers sjukdom
    Vetenskapsrådet
    1 January 2024 - 31 December 2027
  • Nya innovativa vägar mot Alzheimers sjukdom: Vätskebiomarkörer och intracellulära behandlingar
    Private donation from Leif Lundblad Family and others
    1 October 2023 - 30 September 2026
  • Potential för extracellulära mitokondrier för terapi och diagnos vid Alzheimers
    Petrus och Augusta Hedlunds Stiftelse
    2 January 2022 - 31 January 2024
  • Mitochondria on the road: neuroglial crosstalk in Alzheimer’s disease
    StartNeuro – funding for postdoctoral researchers
    1 June 2020 - 31 December 2021
  • Exploring extracellular mitochondria in Alzheimer's disease: from organelle-based therapy to biomarkers
    Alzheimerfonden
    1 January 2020 - 31 December 2023

Anställningar

  • Biträdande Lektor, Neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2022-2028
  • Postdoctoral Researcher, Mitochondria and neurodegeneration, Center for Neuroscience and Cell Biology (CNC), 2017-2018

Examina och utbildning

  • PhD in Neurosciences, Health Sciences – field Neuroscience, Role of lysine deacetylases on transcription regulation and mitochondrial function in Huntington's disease, Faculty of Medicine, University of Coimbra, 2017
  • Master in Biotechnology, Biotechnology in Health Sciences, University of Trás-os-Montes and Alto Douro, 2011
  • Bachelor in Genetics and Biotechnology, University of Trás-os-Montes and Alto Douro, 2008

Nyheter från KI

Kalenderhändelser från KI