Lisa Juntti-Berggren

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Populärvetenskap och samverkan

Om mig

Lisa Juntti-Berggren, professor i experimentell medicin vid institutionen för molekylär medicin och kirurgi, forskar om diabetes med särskild inriktning på apolipoprotein CIII. Hennes mål är att hitta nya läkemedel för prevention och behandling av sjukdomen.

Artiklar

Article: CELLULAR SIGNALLING. 2023;102:110535
ATF5 is a regulator of ER stress and β-cell apoptosis in different mouse models of genetic- and diet-induced obesity and diabetes mellitus
Ma J; Liu Y; Valladolid-Acebes I; Recio-Lopez P; Peng G; Li J; Berggren P-O; Juntti-Berggren L; Tong N
Article: BIOFACTORS. 2023;49(1):153-172
Treatment of the metabolic syndrome by siRNA targeting apolipoprotein CIII
Recio-Lopez P; Valladolid-Acebes I; Hadwiger P; Hossbach M; Krampert M; Prata C; Berggren P-O; Juntti-Berggren L
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;23(1):62
Apolipoprotein CIII Reduction Protects White Adipose Tissues against Obesity-Induced Inflammation and Insulin Resistance in Mice
Recio-Lopez P; Valladolid-Acebes I; Berggren P-O; Juntti-Berggren L
Article: SCIENCE ADVANCES. 2021;7(11):eabc2931
Lowering apolipoprotein CIII protects against high-fat diet-induced metabolic derangements
Valladolid-Acebes I; Avall K; Recio-Lopez P; Moruzzi N; Bryzgalova G; Bjornholm M; Krook A; Alonso EF; Ericsson M; Landfors F; Nilsson SK; Berggren P-O; Juntti-Berggren L
Article: VIRAL IMMUNOLOGY. 2020;33(9):594-599
Effectiveness of Antivirals in a Type 1 Diabetes Model and the Move Toward Human Trials
Niklasson B; Klitz W; Juntti-Berggren L; Berggren P-O; Lindquist L
Article: SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION. 2020;80(3):230-235
Human apolipoprotein CIII levels; evaluation of three assay methods
Sandin A; Olofsson C; Stralfors A; Ekberg NR; Brismar K; Juntti-Berggren L; Eggertsen G
Article: CELL TRANSPLANTATION. 2020;29:963689720913256-096368972091325
Islet Transplantation to the Anterior Chamber of the Eye-A Future Treatment Option for Insulin-Deficient Type-2 Diabetics? A Case Report from a Nonhuman Type-2 Diabetic Primate
Tun SBB; Chua M; Hasan R; Kohler M; Zheng X; Ali Y; Abdulreda MH; Juntti-Berggren L; Barathi VA; Berggren P-O
Article: LABORATORY ANIMAL RESEARCH. 2018;34(3):126-131
Neither polyphenol-rich red wine nor fenofibrate affects the onset of type-1 diabetes mellitus in the BB rat.
Åvall K; Berggren P-O; Juntti-Berggren L
Article: VIRAL IMMUNOLOGY. 2016;29(8):452-458
Diabetes Prevention Through Antiviral Treatment in Biobreeding Rats
Niklasson B; Arbrandt G; Kawecki A; Juntti-Berggren L; Berggren P-O; Al-Qahtani SM; Gustafsson A-L; Bryzgalova G; Klitz W
Article: FASEB JOURNAL. 2016;30(2):884-894
Cathelicidins positively regulate pancreatic β-cell functions
Sun J; Xu M; Ortsater H; Lundeberg E; Juntti-Berggren L; Chen YQ; Haeggstrom JZ; Gudmundsson GH; Diana J; Agerberth B
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(20):E2611-E2619
Apolipoprotein CIII links islet insulin resistance to β-cell failure in diabetes
Avall K; Ali Y; Leibiger IB; Leibiger B; Moede T; Paschen M; Dicker A; Dare E; Kohler M; Ilegems E; Abdulreda MH; Graham M; Crooke RM; Tay VSY; Refai E; Nilsson SK; Jacob S; Selander L; Berggren P-O; Juntti-Berggren L
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2015;72(6):1197-1207
Ca_V1.2 and Ca_V1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum
Yang G; Shi Y; Yu J; Li Y; Yu L; Welling A; Hofmann F; Striessnig J; Juntti-Berggren L; Berggren P-O; Yang S-N
Article: DIABETES. 2014;63(12):4100-4114
Defects in β-Cell Ca²⁺ Dynamics in Age-Induced Diabetes
Li L; Trifunovic A; Kohler M; Wang Y; Berglund JP; Illies C; Juntti-Berggren L; Larsson N-G; Berggren P-O
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2014;71(7):1289-1303
Apolipoprotein CIII hyperactivates β cell Ca_V1 channels through SR-BI/β1 integrin-dependent coactivation of PKA and Src
Shi Y; Yang G; Yu J; Yu L; Westenbroek R; Catterall WA; Juntti-Berggren L; Berggren P-O; Yang S-N
Article: BMC PHYSIOLOGY. 2012;12:14
Localization of lipoprotein lipase and GPIHBP1 in mouse pancreas: effects of diet and leptin deficiency.
Nyrén R; Chang CL; Lindström P; Barmina A; Vorrsjö E; Ali Y; Juntti-Berggren L; Bensadoun A; Young SG; Olivecrona T; Olivecrona G
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2012;69(10):1733-1743
Transthyretin binds to glucose-regulated proteins and is subjected to endocytosis by the pancreatic β-cell
Dekki N; Refai E; Holmberg R; Kohler M; Jornvall H; Berggren P-O; Juntti-Berggren L
Article: INTEGRATIVE BIOLOGY. 2012;4(2):209-219
One-step purification of functional human and rat pancreatic alpha cells
Koehler M; Dare E; Ali MY; Rajasekaran SS; Moede T; Leibiger B; Leibiger IB; Tibell A; Juntti-Berggren L; Berggren P-O
Article: ENDOCRINOLOGY. 2011;152(8):3040-3048
Apolipoprotein CIII Reduces Proinflammatory Cytokine-Induced Apoptosis in Rat Pancreatic Islets via the Akt Prosurvival Pathway
Storling J; Juntti-Berggren L; Olivecrona G; Prause MC; Berggren P-O; Mandrup-Poulsen T
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(26):10685-10689
Lowering apolipoprotein CIII delays onset of type 1 diabetes
Holmberg R; Refai E; Hoog A; Crooke RM; Graham M; Olivecrona G; Berggren P-O; Juntti-Berggren L
Article: JOURNAL OF MEDICAL CASE REPORTS. 2010;4:315
Electrical short-circuit in β-cells from a patient with non-insulinoma pancreatogenous hypoglycemic syndrome (NIPHS): a case report.
Bränström R; Berglund E; Curman P; Forsberg L; Höög A; Grimelius L; Berggren P-O; Mattsson P; Hellman P; Juntti-Berggren L
Article: CELL METABOLISM. 2010;12(3):237-249
Interleukin-6 Signaling in Liver-Parenchymal Cells Suppresses Hepatic Inflammation and Improves Systemic Insulin Action
Wunderlich FT; Stroehle P; Koenner AC; Gruber S; Tovar S; Broenneke HS; Juntti-Berggren L; Li L-S; van Rooijen N; Libert C; Berggren P-O; Bruening JC
Article: MICROBIOLOGY AND IMMUNOLOGY. 2009;53(10):567-572
Antiviral treatments reduce severity of diabetes in Ljungan virus-infected CD-1 mice and delay onset in diabetes-prone BB rats
Holmberg R; Klitz W; Blixt M; Berggren P-O; Juntti-Berggren L; Niklasson B
Article: BIOSCIENCE REPORTS. 2007;27(6):321-326
Type 1 diabetic serum interferes with pancreatic β-cell Ca²⁺-handling
Dekki N; Nilsson R; Norgren S; Roessner SM; Appelskog I; Marcus C; Simell O; Pugliese A; Alejandro R; Ricordi C; Berggren PO; Juntti-Berggren L
Article: PSYCHONEUROENDOCRINOLOGY. 2007;32(8-10):1041-1051
Predictors of cognitive impairment in type 1 diabetes
Brismar T; Maurex L; Cooray G; Juntti-Berggren L; Lindstrom P; Ekberg K; Adner N; Andersson S
Article: CELL METABOLISM. 2007;6(3):217-228
Glucose recruits K_ATP channels via non-insulin-containing dense-core granules
Yang S-N; Wenna ND; Yu J; Yang G; Qiu H; Yu L; Juntti-Berggren L; Koher M; Berggren P-O
Article: DIABETES CARE. 2007;30(1):71-76
C-peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy
Ekberg K; Brismar T; Johansson B-L; Lindstrom P; Juntti-Berggren L; Norbhy A; Berne C; Arnqvist HJ; Bolinder J; Wahren J
Article: DIABETES. 2006;55(12):3299-3308
Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal β-cell growth
Miettinen PJ; Ustinov J; Ormio P; Gao R; Palgi J; Hakonen E; Juntti-Berggren L; Berggren P-O; Otonkoski T
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(47):17020-17025
Transthyretin constitutes a functional component in pancreatic β-cell stimulus-secretion coupling
Refai E; Dekki N; Yang SN; Imreh G; Cabrera O; Yu LN; Yang G; Norgren S; Rössner SM; Inverardi L; Ricordi C; Olivecrona G; Andersson M; Jörnvall H; Berggren PO; Juntti-Berggren L
Article: CELL. 2004;119(2):273-284
Removal of Ca²⁺ channel β₃ Subunit enhances Ca²⁺ oscillation frequency and insulin exocytosis
Berggren PO; Yang SN; Murakami M; Efanov AM; Uhles S; Köhler M; Moede T; Fernström A; Appelskog LB; Aspinwall CA; Zaitsev SV; Larsson O; de Vargas LM; Fecher-Trost C; Weissgerber P; Ludwig A; Leibiger B; Juntti-Berggren L; Barker CJ; Gromada J; Freichel M; Leibiger IB; Flockerzi V
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(27):10090-10094
Apolipoprotein CIII promotes Ca²⁺-dependent β cell death in type 1 diabetes
Juntti-Berggren L; Refai E; Appelskog I; Andersson M; Imreh G; Dekki N; Uhles S; Yu L; Griffiths WJ; Zaitsev S; Leibiger I; Yang SN; Olivecrona G; Jörnvall H; Berggren PO
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(42):40710-40716
Dihydroxyacetone-induced oscillations in cytoplasmic free Ca²⁺ and the ATP/ADP ratio in pancreatic β-cells at substimulatory glucose
Juntti-Berggren L; Webb DL; Arkhammar POG; Schultz V; Schweda EKH; Tornheim K; Berggren PO
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(40):37176-37183
Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose
Shiota C; Larsson O; Shelton KD; Shiota M; Efanov AM; Hoy M; Lindner J; Kooptiwut S; Juntti-Berggren L; Gromada J; Berggren PO; Magnuson MA
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2002;59(7):1185-1189
Proinsulin C-peptide and its analogues induce intracellular Ca²⁺ increases in human renal tubular cells
Shafqat J; Juntti-Berggren L; Zhong Z; Ekberg K; Köhler M; Berggren PO; Johansson J; Wahren J; Jörnvall H
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(36):34199-34205
Cyclin-dependent kinase 5 promotes insulin exocytosis
Lilja L; Yang SN; Webb DL; Juntti-Berggren L; Berggren PO; Bark C
Article: ATHEROSCLEROSIS. 2000;153(1):23-35
7β-hydroxycholesterol induces Ca²⁺ oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells
Ares MPS; Pörn-Ares MI; Moses S; Thyberg J; Juntti-Berggren L; Berggren PO; Hultgårdh-Nilsson A; Kallin B; Nilsson J
Article: DIABETES, NUTRITION AND METABOLISM - CLINICAL AND EXPERIMENTAL. 2000;13(1):7-12
Influence of acarbose on post-prandial insulin requirements in patients with Type 1 diabetes
Juntti-Berggren L; Pigon J; Hellström P; Holst JJ; Efendic S
Article: FEBS LETTERS. 1998;439(3):267-270
An endogenous peptide isolated from the gut, NK-lysin, stimulates insulin secretion without changes in cytosolic free Ca²⁺ concentration
Zaitsev SV; Andersson M; Efanov AM; Efanova IB; Östenson CG; Juntti-Berggren L; Berggren PO; Mutt V; Efendic S
Article: PANCREAS. 1998;16(2):134-140
X-ray microanalysis of in situ and isolated pancreatic islets
Wróblewski R; Pålsgård E; Juntti-Berggren L; Berggren PO; Roomans GM
Article: JOURNAL OF LIPID RESEARCH. 1997;38(10):2049-2061
Ca2+ channel blockers verapamil and nifedipine inhibit apoptosis induced by 25-hydroxycholesterol in human aortic smooth muscle cells
Ares MPS; PornAres MI; Thyberg J; JunttiBerggren L; Berggren PO; Diczfalusy U; Kallin B; Bjorkhem I; Orrenius S; Nilsson J
Article: DIABETES CARE. 1996;19(11):1200-1206
The antidiabetogenic effect of GLP-1 is maintained during a 7-day treatment period and improves diabetic dyslipoproteinemia in NIDDM patients
JunttiBerggren L; Pigon J; Karpe F; Hamsten A; Gutniak M; Vignati L; Efendic S
Article: DIABETES CARE. 1996;19(8):857-863
Glucagon-like peptide I enhances the insulinotropic effect of glibenclamide in NIDDM patients and in the perfused rat pancreas.
Gutniak MK; Juntti-Berggren L; Hellström PM; Guenifi A; Holst JJ; Efendic S
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(30):18154-18160
Reversible Ca2+-dependent translocation of protein kinase C and glucose-induced insulin release
Deeney JT; Cunningham BA; Chheda S; Bokvist K; JunttiBerggren L; Lam K; Korchak HM; Corkey BE; Berggren PO
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1995;111(2):159-165
INTERLEUKIN-1-BETA-INDUCED STIMULATION OF INSULIN RELEASE IN MOUSE PANCREATIC-ISLETS IS RELATED TO DIACYLGLYCEROL PRODUCTION AND PROTEIN-KINASE-C ACTIVATION
EIZIRIK DL; SANDLER S; WELSH N; JUNTTIBERGGREN L; BERGGREN PO
Article: CELL BIOLOGY INTERNATIONAL. 1995;19(1):25-34
EFFECTS OF K+-INDUCED DEPOLARIZATION AND PURINERGIC RECEPTOR ACTIVATION ON ELEMENTAL CONTENT IN INSULIN-PRODUCING RINM5F-CELLS
PALSGARD E; LINDH U; JUNTTIBERGGREN L; BERGGREN PO; ROOMANS GM
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Alla övriga publikationer

Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(2):932
Apolipoprotein CIII Is an Important Piece in the Type-1 Diabetes Jigsaw Puzzle
Valladolid-Acebes I; Berggren P-O; Juntti-Berggren L
Review: NEUROENDOCRINOLOGY LETTERS. 2019;40(4):175-183
Non-functioning neuroendocrine pancreatic tumors transforming to malignant insulinomas - four cases and review of the literature
Juhlin CC; Skoglund S; Juntti-Berggren L; Karlberg M; Calissendorff J
Letter: DIABETES & METABOLISM. 2018;44(3):303-304
The yin and yang of apolipoprotein CIII
Avall K; Berggren P-O; Juntti-Berggren L
Review: CURRENT OPINION IN LIPIDOLOGY. 2017;28(1):27-31
Apolipoprotein CIII is a new player in diabetes
Juntti-Berggren L; Berggren P-O
Editorial comment: CELL CYCLE. 2015;14(17):2715-2716
The pancreatic β-cell in deadly encounter with apolipoprotein CIII
Juntti-Berggren L; Ali Y; Berggren P-O
Letter: EUROPEAN RESPIRATORY JOURNAL. 2008;32(5):1420-1421
Breathless after separation ... from tumour
Catrina S-B; Juntti-Berggren L
Corrigendum: DIABETOLOGIA. 2007;50(10):2227
The BioBreeding rat diabetes model is infected with Ljungan virus (vol 50, pg 1559, 2007)
Niklasson B; Hultman T; Kallies R; Niedrig M; Nilsson R; Berggren P-O; Juntti-Berggren L; Efendic S; Lernmark A; Klitz W
Letter: DIABETOLOGIA. 2007;50(7):1559-1560
The BioBreeding rat diabetes model is infected with Ljungan virus
Niklasson B; Hultman T; Kallies R; Niedrig M; Nilsson R; Berggren P-O; Juntti-Berggren L; Efendic S; Lernmark A; Klitz W
Published conference paper: DIABETES. 2001;50:S77-S81
Effects of serum from patients with type 1 diabetes on primary cerebellar granule cells
Chandra J; Yang SN; Köhler M; Zaitsev S; Juntti-Berggren L; Berggren PO; Zhivotovsky B; Orrenius S
Published conference paper: DIABETES. 2001;50:S44-S47
Role of apoptosis in pancreatic β-cell death in diabetes
Chandra J; Zhivotovsky B; Zaitsev S; Juntti-Berggren L; Berggren PO; Orrenius S

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