Laura Baranello

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: SCIENCE ADVANCES. 2023;9(41):eadg5109
Coinhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills pancreatic cancer via readthrough transcription
Cameron DP; Grosser J; Ladigan S; Kuzin V; Iliopoulou E; Wiegard A; Benredjem H; Jackson K; Liffers ST; Lueong S; Cheung PF; Vangala D; Pohl M; Viebahn R; Teschendorf C; Wolters H; Usta S; Geng K; Kutter C; Arsenian-Henriksson M; Siveke JT; Tannapfel A; Schmiegel W; Hahn SA; Baranello L
Article: SCIENCE ADVANCES. 2023;9(30):eadg1805
Control of protein synthesis through mRNA pseudouridylation by dyskerin
Pederiva C; Trevisan DM; Peirasmaki D; Chen S; Savage SA; Larsson O; Ule J; Baranello L; Agostini F; Farnebo M
Article: SCIENCE ADVANCES. 2022;8(49):eabq0648
NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors
Meroni A; Grosser J; Agashe S; Ramakrishnan N; Jackson J; Verma P; Baranello L; Vindigni A
Article: STAR PROTOCOLS. 2022;3(3):101581
TOP1 CAD-seq: A protocol to map catalytically engaged topoisomerase 1 in human cells
Kuzin V; Wiegard A; Cameron DP; Baranello L
Article: CANCER RESEARCH COMMUNICATIONS. 2022;2(3):182-201
MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner
Castell A; Yan Q; Fawkner K; Bazzar W; Zhang F; Wickstrom M; Alzrigat M; Franco M; Krona C; Cameron DP; Dyberg C; Olsen TK; Verschut V; Schmidt L; Lim SY; Mahmoud L; Hydbring P; Lehmann S; Baranello L; Nelander S; Johnsen JI; Larsson L-G
Article: MOLECULAR CELL. 2022;82(1):140-158.e12
MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome"
Das SK; Kuzin V; Cameron DP; Sanford S; Jha RK; Nie Z; Rosello MT; Holewinski R; Andresson T; Wisniewski J; Natsume T; Price DH; Lewis BA; Kouzine F; Levens D; Baranello L
Article: MOLECULAR CELL. 2021;81(24):5007-5024.e9
Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1
Wiegard A; Kuzin V; Cameron DP; Grosser J; Ceribelli M; Mehmood R; Ballarino R; Valant F; Grochowski R; Karabogdan I; Crosetto N; Lindqvist A; Bizard AH; Kouzine F; Natsume T; Baranello L
Article: PLOS PATHOGENS. 2021;17(9):e1009954
The Epstein-Barr virus deubiquitinating enzyme BPLF1 regulates the activity of topoisomerase II during productive infection
Li J; Nagy N; Liu J; Gupta S; Frisan T; Hennig T; Cameron DP; Baranello L; Masucci MG
Article: PLOS GENETICS. 2021;17(9):e1009763
Deficiency of Polη in Saccharomyces cerevisiae reveals the impact of transcription on damage-induced cohesion
Wu P-S; Grosser J; Cameron DP; Baranello L; Strom L
Article: LIFE SCIENCE ALLIANCE. 2021;4(3):e202000980
Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1
Cascales HS; Burdova K; Middleton A; Kuzin V; Mullers E; Stoy H; Baranello L; Macurek L; Lindqvist A
Article: METHODS IN MOLECULAR BIOLOGY. 2021;2318:161-185
Analysis of Myc Chromatin Binding by Calibrated ChIP-Seq Approach.
Cameron DP; Kuzin V; Baranello L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(24):13457-13467
MYC protein stability is negatively regulated by BRD4
Devaiah BN; Mu J; Akman B; Uppal S; Weissman JD; Cheng D; Baranello L; Nie Z; Levens D; Singer DS
Article: MOLECULAR CELL. 2019;75(2):267-283.e12
Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations
Gothe HJ; Bouwman BAM; Gusmao EG; Piccinno R; Petrosino G; Sayols S; Drechsel O; Minneker V; Josipovic N; Mizi A; Nielsen CF; Wagner E-M; Takeda S; Sasanuma H; Hudson DF; Kindler T; Baranello L; Papantonis A; Crosetto N; Roukos V
Article: CELL. 2018;173(5):1165-1178.e20
The Energetics and Physiological Impact of Cohesin Extrusion
Vian L; Pekowska A; Rao SSP; Kieffer-Kwon K-R; Jung S; Baranello L; Huang S-C; El Khattabi L; Dose M; Pruett N; Sanborn AL; Canela A; Maman Y; Oksanen A; Resch W; Li X; Lee B; Kovalchuk AL; Tang Z; Nelson S; Di Pierro M; Cheng RR; Machol I; St Hilaire BG; Durand NC; Shamim MS; Stamenova EK; Onuchic JN; Ruan Y; Nussenzweig A; Levens D; Aiden EL; Casellas R
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2018;19(3):E884-884
DNA Supercoiling, Topoisomerases, and Cohesin: Partners in Regulating Chromatin Architecture?
Bjorkegren C; Baranello L
Article: METHODS IN MOLECULAR BIOLOGY. 2018;1672:155-166
Mapping DNA Breaks by Next-Generation Sequencing.
Baranello L; Kouzine F; Wojtowicz D; Cui K; Zhao K; Przytycka TM; Capranico G; Levens D
Article: METHODS IN MOLECULAR BIOLOGY. 2018;1703:95-108
The Use of Psoralen Photobinding to Study Transcription-Induced Supercoiling.
Kouzine F; Baranello L; Levens D
Article: MOLECULAR CELL. 2017;67(6):1013-1025.e9
Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response
Porter JR; Fisher BE; Baranello L; Liu JC; Kambach DM; Nie Z; Koh WS; Luo J; Stommel JM; Levens D; Batchelor E
Article: MOLECULAR CELL. 2017;67(4):566-578.e10
Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation
Kieffer-Kwon K-R; Nimura K; Rao SSP; Xu J; Jung S; Pekowska A; Dose M; Stevens E; Mathe E; Dong P; Huang S-C; Ricci MA; Baranello L; Zheng Y; Ardori FT; Resch W; Stavreva D; Nelson S; McAndrew M; Casellas A; Finn E; Gregory C; St Hilaire BG; Johnson SM; Dubois W; Cosma MP; Batchelor E; Levens D; Phair RD; Misteli T; Tessarollo L; Hager G; Lakadamyali M; Liu Z; Floer M; Shroff H; Aiden EL; Casellas R
Article: CELL SYSTEMS. 2017;4(3):344-356.e7
Permanganate/S1 Nuclease Footprinting Reveals Non-B DNA Structures with Regulatory Potential across a Mammalian Genome
Kouzine F; Wojtowicz D; Baranello L; Yamane A; Nelson S; Resch W; Kieffer-Kwon K-R; Benham CJ; Casellas R; Przytycka TM; Levens D
Journal article: BIOPHYSICAL REVIEWS. 2016;8(3):259-268
Controlling gene expression by DNA mechanics: emerging insights and challenges.
Levens D; Baranello L; Kouzine F
Article: CHROMOSOME RESEARCH. 2016;24(2):175-181
ChIP bias as a function of cross-linking time
Baranello L; Kouzine F; Sanford S; Levens D
Article: CELL. 2016;165(2):357-371
RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription
Baranello L; Wojtowicz D; Cui K; Devaiah BN; Chung H-J; Chan-Salis KY; Guha R; Wilson K; Zhang X; Zhang H; Piotrowski J; Thomas CJ; Singer DS; Pugh BF; Pommier Y; Przytycka TM; Kouzine F; Lewis BA; Zhao K; Levens D
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2016;98(4):627-642
GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy
Kuschal C; Botta E; Orioli D; Digiovanna JJ; Seneca S; Keymolen K; Tamura D; Heller E; Khan SG; Caligiuri G; Lanzafame M; Nardo T; Ricotti R; Peverali FA; Stephens R; Zhao Y; Lehmann AR; Baranello L; Levens D; Kraemer KH; Stefanini M
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2014;15(7):13111-13122
DNA Break Mapping Reveals Topoisomerase II Activity Genome-Wide
Baranello L; Kouzine F; Wojtowicz D; Cui K; Przytycka TM; Zhao K; Levens D
Article: NUCLEUS. 2014;5(3):195-202
DNA topology and transcription
Kouzine F; Levens D; Baranello L
Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2013;20(3):396-403
Transcription-dependent dynamic supercoiling is a short-range genomic force
Kouzine F; Gupta A; Baranello L; Wojtowicz D; Ben-Aissa K; Liu J; Przytycka TM; Levens D
Article: NUCLEIC ACIDS RESEARCH (NAR). 2010;38(1):159-171
DNA topoisomerase I inhibition by camptothecin induces escape of RNA polymerase II from promoter-proximal pause site, antisense transcription and histone acetylation at the human HIF-1α gene locus
Baranello L; Bertozzi D; Fogli MV; Pommier Y; Capranico G
Article: BIOCHIMIE. 2007;89(4):482-489
The effects of camptothecin on RNA polymerase II transcription: roles of DNA topoisomerase I.
Capranico G; Ferri F; Fogli MV; Russo A; Lotito L; Baranello L
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Alla övriga publikationer

Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):13A
Organisation and Function of DNA Supercoiling in the Human Genome
Levens D; Kouzine F; Baranello LF
Book chapter: NUCLEAR ARCHITECTURE AND DYNAMICS. 2018;p. 81-99
3 DNA Supercoiling(omics)
Baranello L; Levens D; Kouzine F
Preprint: BIORXIV. 2017
Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1
Cascales HS; Burdova K; Middleton A; Kuzin V; Müllers E; Stoy H; Baranello L; Macurek L; Lindqvist A
Review: BIOPHYSICAL REVIEWS. 2016;8(Suppl 1):23-32
Controlling gene expression by DNA mechanics: emerging insights and challenges.
Levens D; Baranello L; Kouzine F
Editorial comment: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(3):889-890
CTCF and cohesin cooperate to organize the 3D structure of the mammalian genome
Baranello L; Kouzine F; Levens D
Review: TRANSCRIPTION. 2013;4(5):232-237
DNA topoisomerases beyond the standard role.
Baranello L; Kouzine F; Levens D
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2012;1819(7):632-638
The importance of being supercoiled: How DNA mechanics regulate dynamic processes
Baranello L; Levens D; Gupta A; Kouzine F
Book chapter: DNA TOPOISOMERASES AND CANCER: CANCER DRUG DISCOVERY AND DEVELOPMENT. 2012;p. 309-324
Transcriptional Stress by Camptothecin: Mechanisms and Implications for the Drug Antitumor Activity
Capranico G; Baranello L; Bertozzi D; Marinello J
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2010;1806(2):240-250
Dissecting the transcriptional functions of human DNA topoisomerase I by selective inhibitors: Implications for physiological and therapeutic modulation of enzyme activity
Capranico G; Marinello J; Baranello L

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