Katarina le Blanc

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Professor i klinisk stamcellsforskning med fokus på mesenkymala stromaceller.

Artiklar

Journal article: CYTOTHERAPY. 2025
Defining minimal criteria for peer-reviewed reporting of mesenchymal stromal cell clinical trials for autoimmune diseases
Davies LC; Biard L; García-Olmo D; Gilkeson G; Gnecchi M; Kurtzberg J; Kogler G; Le Blanc K; Lowdell MW; Pers Y-M; Sun L-Y; Tarte K; Uccelli A; Sanchez-Guijo F; Farge D; Diseases IECWGOT
Article: STEM CELL RESEARCH & THERAPY. 2024;15(1):77
Transcriptomic and proteomic profiles of fetal versus adult mesenchymal stromal cells and mesenchymal stromal cell-derived extracellular vesicles
Gencer EB; Lor YK; Abomaray F; El Andaloussi S; Pernemalm M; Sharma N; Hagey DW; Gorgens A; Gustafsson MO; Le Blanc K; Toonsi MA; Walther-Jallow L; Goetherstrom C
Article: ORAL DISEASES. 2023;29(8):3346-3359
Immunohistopathology of oral mucosal chronic graft-versus-host disease severity and duration
Tollemar V; Strom J; Tudzarovski N; Habel H; Legert KG; Heymann R; Warfvinge G; Le Blanc K; Sugars RV
Article: CYTOTHERAPY. 2023;25(9):956-966
Lysis and phenotypic modulation of mesenchymal stromal cells upon blood contact triggers anti-inflammatory skewing of the peripheral innate immune repertoire
Davies LC; Queckborner S; Jylha CE; Andren AT; Forshell TZP; Le Blanc K
Article: CYTOTHERAPY. 2023;25(8):803-807
An International Society for Cell and Gene Therapy Mesenchymal Stromal Cells (MSC) Committee perspectives on International Standards Organization/Technical Committee 276 Biobanking Standards for bone marrow-MSCs and umbilical cord tissue-derived MSCs for research purposes
Viswanathan S; Le Blanc K; Ciccocioppo R; Dagher G; Filiano AJ; Galipeau J; Krampera M; Krieger L; Lalu MM; Nolta J; Pardo VMR; Shi Y; Tarte K; Weiss DJ; Martin I
Article: BLOOD. 2023;142(1):73-89
Characterization of the bone marrow niche in patients with chronic myeloid leukemia identifies CXCL14 as a new therapeutic option
Dolinska M; Cai H; Mansson A; Shen J; Xiao P; Bouderlique T; Li X; Leonard E; Chang M; Gao Y; Medina JP; Kondo M; Sandhow L; Johansson A-SF; Deneberg S; Soederlund S; Jaedersten M; Ungerstedt J; Tobiasson M; Ostman A; Mustjoki S; Stenke L; Le Blanc K; Hellstroem-Lindberg E; Lehmann S; Ekblom M; Olsson-Stroemberg U; Sigvarosson M; Qian H
Journal article: BIOMATERIALS ADVANCES. 2023;147:213331
Biomimetic polyelectrolyte coating of stem cells suppresses thrombotic activation and enhances its survival and function
Rangasami VK; Asawa K; Teramura Y; Le Blanc K; Nilsson B; Varghese OP; Oommen OP
Article: HELIYON. 2023;9(4):e15517
Grading of minor salivary gland immuno-histopathology post-allogenic hematopoietic cell transplantation
Tollemar V; Arvidsson H; Habel H; Tudzarovski N; Legert KG; Le Blanc K; Warfvinge G; Sugars RV
Article: LEUKEMIA. 2023;37(4):888-900
Cognitive impairments correlate with increased central nervous system immune activation after allogeneic haematopoietic stem cell transplantation
Boberg E; Kadri N; Hagey DWW; Schwieler L; El Andaloussi S; Erhardt S; Iacobaeus E; Le Blanc K
Article: METABOLISM OPEN. 2022;13:100167
Diversity of respiratory parameters and metabolic adaptation to low oxygen tension in mesenchymal stromal cells
Olesen K; Moruzzi N; Bulatovic I; Folmes C; Jeon R; Felldin U; Terzic A; Simonson OE; Le Blanc K; Osterholm C; Berggren P-O; Schiffer T; Rodin S; Tilevik A; Grinnemo K-H
Article: BONE MARROW TRANSPLANTATION. 2022;57(3):360-369
Reduced prefrontal cortex and sympathetic nervous system activity correlate with fatigue after aHSCT
Boberg E; Iacobaeus E; Greenfield MS; Wang Y; Msghina M; Le Blanc K
Article: CYTOTHERAPY. 2021;23(12):1060-1063
Consensus International Council for Commonality in Blood Banking Automation-International Society for Cell & Gene Therapy statement on standard nomenclature abbreviations for the tissue of origin of mesenchymal stromal cells
Viswanathan S; Ciccocioppo R; Galipeau J; Krampera M; Le Blanc K; Martin I; Moriz K; Nolta J; Phinney DG; Shi Y; Szczepiorkowski ZM; Tarte K; Weiss DJ; Ashford P
Article: LANCET NEUROLOGY. 2021;20(11):917-929
Safety, tolerability, and activity of mesenchymal stem cells versus placebo in multiple sclerosis (MESEMS): a phase 2, randomised, double-blind crossover trial
Uccelli A; Laroni A; Ali R; Battaglia MA; Blinkenberg M; Brundin L; Clanet M; Fernandez O; Marriot J; Muraro P; Nabavi SM; Oliveri RS; Radue E; Tello CR; Schiavetti I; Sellner J; Sorensen PS; Sormani MP; Wuerfel JT; Freedman MS
Article: CYTOTHERAPY. 2021;23(5):368-372
Mesenchymal stromal cell variables influencing clinical potency: the impact of viability, fitness, route of administration and host predisposition
Galipeau J; Krampera M; Leblanc K; Nolta JA; Phinney DG; Shi Y; Tarte K; Viswanathan S; Martin I
Article: STEM CELLS AND DEVELOPMENT. 2021;30(3):119-127
The Coronavirus Pandemic: A Pitfall or a Fast Track for Validating Cell Therapy Products?
Khoury M; Ikonomou L; Dominici M; LeBlanc K; Levine BL; Weiss DJ
Article: CYTOTHERAPY. 2020;22(11):602-605
Cell-based therapies for coronavirus disease 2019: proper clinical investigations are essential
Khoury M; Rocco PRM; Phinney DG; Krampera M; Martin I; Viswanathan S; Nolta JA; LeBlanc K; Galipeau J; Weiss DJ
Article: STEM CELLS TRANSLATIONAL MEDICINE. 2020;9(10):1190-1202
Treatment of chronicGvHDwith mesenchymal stromal cells induces durable responses: A phaseIIstudy
Boberg E; von Bahr L; Afram G; Lindstrom C; Ljungman P; Heldring N; Petzelbauer P; Legert KG; Kadri N; Le Blanc K
Article: STEM CELL RESEARCH & THERAPY. 2020;11(1):128
Treatment of vocal fold scarring with autologous bone marrow-derived human mesenchymal stromal cells-first phase I/II human clinical study
Hertegard S; Nagubothu SR; Malmstrom E; LeBlan K
Article: LARYNGOSCOPE. 2020;130(1):E21-E29
Mesenchymal Stromal Cells Modulate Tissue Repair Responses Within the Injured Vocal Fold
Nagubothu SR; Sugars RV; Tudzarovski N; Andren AT; Bottai M; Davies LC; Hertegard S; Le Blanc K
Article: JOURNAL OF CLINICAL MEDICINE. 2019;8(12):E2102-2102
Short and Long Term Clinical and Immunologic Follow up after Bone Marrow Mesenchymal Stromal Cell Therapy in Progressive Multiple Sclerosis-A Phase I Study
Iacobaeus E; Kadri N; Lefsihane K; Boberg E; Gavin C; Andren AT; Lilja A; Brundin L; Le Blanc K
Article: STEM CELL RESEARCH & THERAPY. 2019;10(1):334
Tissue immune profiles supporting response to mesenchymal stromal cell therapy in acute graft-versus-host disease-a gut feeling
Gavin C; Boberg E; Von Bahr L; Bottai M; Andren AT; Wernerson A; Davies LC; Sugars RV; Le Blanc K
Article: CYTOTHERAPY. 2019;21(10):1019-1024
Mesenchymal stem versus stromal cells: International Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal Cell committee position statement on nomenclature
Viswanathan S; Shi Y; Galipeau J; Krampera M; Leblanc K; Martin I; Nolta J; Phinney DG; Sensebe L
Article: STEM CELLS AND DEVELOPMENT. 2019;28(17):1177-1190
Hyaluronan Hydrogels for the Local Delivery of Mesenchymal Stromal Cells to the Injured Vocal Fold
Hertegard S; Nagubothu SR; Malmstrom E; Strom CE; Tolf A; Davies LC; Le Blanc K
Journal article: CYTOTHERAPY. 2019;21(7):782-792
Manufacturing mesenchymal stromal cells for clinical applications: A survey of Good Manufacturing Practices at US academic centers
Phinney DG; Galipeau J; Krampera M; Le Blanc K; Martin I; Nolta J; Sensebe L; Shi Y; Viswanathan S; Poole B; Bockhold S
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2249
The Complement System Is Essential for the Phagocytosis of Mesenchymal Stromal Cells by Monocytes
Gavin C; Meinke S; Heldring N; Heck KA; Achour A; Iacobaeus E; Le Blanc K; Kadri N; Hoglund P
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2018;24(11):2365-2370
Manufacturing Mesenchymal Stromal Cells for the Treatment of Graft-versus-Host Disease: A Survey among Centers Affiliated with the European Society for Blood and Marrow Transplantation
Trento C; Bernardo ME; Nagler A; Kuci S; Bornhaeuser M; Koehl U; Strunk D; Galleu A; Sanchez-Guijo F; Gaipa G; Introna M; Bukauskas A; Le Blanc K; Apperley J; Roelofs H; Van Campenhout A; Beguin Y; Kuball J; Lazzari L; Avanzini MA; Fibbe W; Chabannon C; Bonini C; Dazzi F
Article: CYTOMETRY PART B-CLINICAL CYTOMETRY. 2018;93A(10):1051-1059
Quantitative chromogenic immunohistochemical image analysis in cellprofiler software
Tollemar V; Tudzarovski N; Boberg E; Andren AT; Al-Adili A; Le Blanc K; Legert KG; Bottai M; Warfvinge G; Sugars RV
Article: IMMUNOLOGY AND CELL BIOLOGY. 2018;96(8):820-830
Phenotypic and functional alterations of myeloid-derived suppressor cells during the disease course of multiple sclerosis
Iacobaeus E; Douagi I; Jitschin R; Marcusson-Stahl M; Andren AT; Gavin C; Lefsihane K; Davies LC; Mougiakakos D; Kadri N; Le Blanc K
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2018;101(5):676-683
Second-line treatment for acute graft-versus-host disease with mesenchymal stromal cells: A decision model
Thielen FW; Blommestein HM; Oosten LEM; Calkoen FG; Lankester AC; Zwaginga JJ; Le Blanc K; Redondo A; Sanchez-Guijo F; Algeri M; Locatelli F; Fibbe WE; Uyl-de Groot CA
Article: STEM CELLS TRANSLATIONAL MEDICINE. 2017;6(10):1840-1851
Dynamic Changes in Brain Mesenchymal Perivascular Cells Associate with Multiple Sclerosis Disease Duration, Active Inflammation, and Demyelination
Iacobaeus E; Sugars RV; Andren AT; Alm JJ; Qian H; Frantzen J; Newcombe J; Alkass K; Druid H; Bottai M; Roytta M; Le Blanc K
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2017;23(4):677-683
Impact of Pretransplantation Indices in Hematopoietic Stem Cell Transplantation: Knowledge of Center-Specific Outcome Data Is Pivotal before Making Index-Based Decisions
Torlen J; Remberger M; Le Blanc K; Ljungman P; Mattsson J
Article: HAEMATOLOGICA. 2017;102(3):498-508
Progression in patients with low- and intermediate-1-risk del(5q) myelodysplastic syndromes is predicted by a limited subset of mutations
Scharenberg C; Giai V; Pellagatti A; Saft L; Dimitriou M; Jansson M; Jadersten M; Grandien A; Douagi I; Neuberg DS; LeBlanc K; Boultwood J; Karimi M; Jacobsen SEW; Woll PS; Hellstrom-Lindberg E
Article: STEM CELLS. 2017;35(3):766-776
Mesenchymal Stromal Cell Secretion of Programmed Death-1 Ligands Regulates T Cell Mediated Immunosuppression
Davies LC; Heldring N; Kadri N; Le Blanc K
Journal article: BLOOD. 2016;128(22):4329
Progression in Patients with with Low- and Intermediate-1 Risk Del(5q) MDS Is Predicted By a Limited Subset of Mutations
Scharenberg C; Woll PS; Giai V; Pellagatti A; Saft L; Dimitriou M; Jädersten M; Jansson M; Douagi I; Neuberg DS; Karimi M; Le Blanc K; Boultwood J; Jacobsen SE; Hellstrom-Lindberg E
Article: STEM CELLS TRANSLATIONAL MEDICINE. 2016;5(11):1485-1495
Type 1 Diabetes Mellitus Donor Mesenchymal. Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro
Davies LC; Alm JJ; Heldring N; Moll G; Gavin C; Batsis I; Qian H; Sigvardsson M; Nilsson B; Kyllonen LE; Salmela KT; Carlsson P-O; Korsgren O; Le Blanc K
Article: CLINICAL CANCER RESEARCH. 2016;22(15):3849-3859
Targeting Suppressive Myeloid Cells Potentiates Checkpoint Inhibitors to Control Spontaneous Neuroblastoma
Mao Y; Eissler N; Le Blanc K; Johnsen JI; Kogner P; Kiessling R
Article: SCIENTIFIC REPORTS. 2016;6:29160
MSC from fetal and adult lungs possess lung-specific properties compared to bone marrow-derived MSC
Enes SR; Sjoland AA; Skog I; Hansson L; Larsson H; Le Blanc K; Eriksson L; Bjermer L; Scheding S; Westergren-Thorsson G
Article: ACTA BIOMATERIALIA. 2016;35:194-205
Heparinization of cell surfaces with short peptide-conjugated PEG-lipid regulates thromboinflammation in transplantation of human MSCs and hepatocytes
Asif S; Ekdahl KN; Fromell K; Gustafson E; Barbu A; Le Blanc K; Nilsson B; Teramura Y
Article: STEM CELL REPORTS. 2016;6(4):607-617
Wnt/β-Catenin Stimulation and Laminins Support Cardiovascular Cell Progenitor Expansion from Human Fetal Cardiac Mesenchymal Stromal Cells
Mansson-Broberg A; Rodin S; Bulatovic I; Ibarra C; Lofling M; Genead R; Wardell E; Felldin U; Granath C; Alici E; Le Blanc K; Smith CIE; Salasova A; Westgren M; Sundstrom E; Uhlen P; Arenas E; Sylven C; Tryggvason K; Corbascio M; Simonson OE; Osterholm C; Grinnemo K-H
Journal article: TRANSPLANTATION AND CELLULAR THERAPY. 2016;22(3):s178
Community Acquired Respiratory Viral Infections (CARV) in Patients with Acute Leukemia and Hematopoietic Stem Cell Transplant (HSCT) Recipients
Trikha G; Hiemenz J; Wingard JR; Zou F; LeBlanc K; Mattsson J; Ljungman PT
Article: STEM CELLS. 2016;34(2):516-521
Mesenchymal Stromal Cells Disrupt mTOR-Signaling and Aerobic Glycolysis During T-Cell Activation
Boettcher M; Hofmann AD; Bruns H; Haibach M; Loschinski R; Saul D; Mackensen A; Le Blanc K; Jitschin R; Mougiakakos D
Article: CYTOTHERAPY. 2016;18(2):151-159
International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials
Galipeau J; Krampera M; Barrett J; Dazzi F; Deans RJ; Debruijn J; Dominici M; Fibbe WE; Gee AP; Gimble JM; Hematti P; Koh MBC; Leblanc K; Martin I; McNiece IK; Mendicino M; Oh S; Ortiz L; Phinney DG; Planat V; Shi Y; Stroncek DF; Viswanathan S; Weiss DJ; Sensebe L
Journal article: BLOOD. 2015;126(23):3138
Treatment of Chronic GvHD with Mesenchymal Stromal Cells Induces Durable Responses; A Phase II Study
Von Bahr L; Davies L; Afram G; Modin C; Garming-Legert K; Hagglund H; Ljungman PT; Le Blanc K
Article: IMMUNOLOGY LETTERS. 2015;168(2):140-146
Mesenchymal stromal cells and the innate immune response
Le Blanc K; Davies LC
Article: STEM CELLS TRANSLATIONAL MEDICINE. 2015;4(10):1199-1213
In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome
Simonson OE; Mougiakakos D; Heldring N; Bassi G; Johansson HJ; Dalen M; Jitschin R; Rodin S; Corbascio M; El Andaloussi S; Wiklander OPB; Nordin JZ; Skog J; Romain C; Koestler T; Hellgren-Johansson L; Schiller P; Joachimsson P-O; Haegglund H; Mattsson M; Lentio J; Faridani OR; Sandberg R; Korsgren O; Krampera M; Weiss DJ; Grinnemo K-H; Le Blanc K
Article: BONE MARROW TRANSPLANTATION. 2015;50(9):1217-1223
Increased incidence of chronic GvHD and CMV disease in patients with vitamin D deficiency before allogeneic stem cell transplantation
von Bahr L; Blennow O; Alm J; Bjorklund A; Malmberg K-J; Mougiakakos D; Le Blanc A; Oefner PJ; Labopin M; Ljungman P; Le Blanc K
Article: CURRENT DIABETES REPORTS. 2015;15(7):46
Mesenchymal Stromal Cells to Halt the Progression of Type 1 Diabetes?
Carlsson P-O; Korsgren O; Le Blanc K
Article: STEM CELLS AND DEVELOPMENT. 2015;24(12):1405-1414
Amniotic Fluid-A Source for Clinical Therapeutics in the Newborn?
Ekblad A; Qian H; Westgren M; Le Blanc K; Fossum M; Gotherstrom C
Article: TRANSPLANT INFECTIOUS DISEASE. 2015;17(3):371-379
Immunogenicity of virosomal adjuvanted trivalent influenza vaccination in allogeneic stem cell transplant recipients
Ambati A; Einarsdottir S; Magalhaes I; Poiret T; Bodenstein R; LeBlanc K; Brune M; Maeurer M; Ljungman P
Article: BLOOD. 2015;125(22):3432-3436
Stromal cell-mediated glycolytic switch in CLL cells involves Notch-c-Myc signaling
Jitschin R; Braun M; Qorraj M; Saul D; Le Blanc K; Zenz T; Mougiakakos D
Journal article: ISBT SCIENCE SERIES. 2015;10(S1):357-365
Engineering more efficient multipotent mesenchymal stromal (stem) cells for systemic delivery as cellular therapy
Moll G; Le Blanc K
Article: BONE MARROW TRANSPLANTATION. 2015;50(2):173-180
SCT for severe autoimmune diseases: consensus guidelines of the European Society for Blood and Marrow Transplantation for immune monitoring and biobanking
Alexander T; Bondanza A; Muraro PA; Greco R; Saccardi R; Daikeler T; Kazmi M; Hawkey C; Simoes P; Leblanc K; Fibbe WE; Moore J; Snarski E; Martin T; Hiepe F; Velardi A; Toubert A; Snowden JA; Farge D
Article: DIABETES. 2015;64(2):587-592
Preserved β-Cell Function in Type 1 Diabetes by Mesenchymal Stromal Cells
Carlsson P-O; Schwarcz E; Korsgren O; Le Blanc K
Journal article: REGENERATIVE MEDICINE. 2015;10(7 Suppl):s96-s296
Poster Presentations.
Article: JOURNAL OF EXTRACELLULAR VESICLES. 2015;4:26316
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting
Wiklander OPB; Nordin JZ; O'Loughlin A; Gustafsson Y; Corso G; Maeger I; Vader P; Lee Y; Sork H; Seow Y; Heldring N; Alvarez-Erviti L; Smith CIE; Le Blanc K; Macchiarini P; Jungebluth P; Wood MJA; EL Andaloussi S
Article: REGENERATIVE MEDICINE RESEARCH. 2015;3:1
Mesenchymal stromal cells support endothelial cell interactions in an intramuscular islet transplantation model
Fransson M; Brannstrom J; Duprez I; Essand M; Le Blanc K; Korsgren O; Magnusson PU
Article: TISSUE ENGINEERING PART A. 2014;20(19-20):2549-2554
White Paper on How to Go Forward with Cell-Based Advanced Therapies in Europe
Erben RG; Silva-Lima B; Reischl I; Steinhoff G; Tiedemann G; Dalemans W; Vos A; Janssen RTA; Le Blanc K; van Osch GJVM; Luyten FP
Article: STEM CELLS. 2014;32(9):2430-2442
Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties?
Moll G; Alm JJ; Davies LC; von Bahr L; Heldring N; Stenbeck-Funke L; Hamad OA; Hinsch R; Ignatowicz L; Locke M; Lonnies H; Lambris JD; Teramura Y; Nilsson-Ekdahl K; Nilsson B; Le Blanc K
Article: BLOOD. 2014;124(5):750-760
CLL-cells induce IDO^hi CD14⁺HLA-DR^lo myeloid-derived suppressor cells that inhibit T-cell responses and promote T_Regs
Jitschin R; Braun M; Buettner M; Dettmer-Wilde K; Bricks J; Berger J; Eckart MJ; Krause SW; Oefner PJ; Le Blanc K; Mackensen A; Mougiakakos D
Article: IMMUNOLOGY. 2014;142(3):431-441
Intranasal delivery of central nervous system-retargeted human mesenchymal stromal cells prolongs treatment efficacy of experimental autoimmune encephalomyelitis
Fransson M; Piras E; Wang H; Burman J; Duprez I; Harris RA; LeBlanc K; Magnusson PU; Brittebo E; Loskog ASI
Article: CYTOTHERAPY. 2014;16(7):915-926
Defined serum-free media for in vitro expansion of adipose-derived mesenchymal stem cells
Al-Saqi SH; Saliem M; Asikainen S; Quezada HC; Ekslad A; Hovatta O; Le Blanc K; Jonasson AF; Gotherstrom C
Article: STEM CELLS TRANSLATIONAL MEDICINE. 2014;3(2):255-264
Pre- and Postnatal Transplantation of Fetal Mesenchymal Stem Cells in Osteogenesis Imperfecta: A Two-Center Experience
Gotherstrom C; Westgren M; Shaw SWS; Astrom E; Biswas A; Byers PH; Mattar CNZ; Graham GE; Taslimi J; Ewald U; Fisk NM; Yeoh AEJ; Lin J-L; Cheng P-J; Choolani M; Le Blanc K; Chan JKY
Article: PLOS ONE. 2014;9(1):e85040
Do ABO Blood Group Antigens Hamper the Therapeutic Efficacy of Mesenchymal Stromal Cells?
Moll G; Hult A; von Bahr L; Alm JJ; Heldring N; Hamad OA; Stenbeck-Funke L; Larsson S; Teramura Y; Roelofs H; Nilsson B; Fibbe WE; Olsson ML; Le Blanc K
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2013;163(4):501-509
Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid-refractory, grade III-IV acute graft-versus-host disease
Ball LM; Bernardo ME; Roelofs H; van Tol MJD; Contoli B; Zwaginga JJ; Avanzini MA; Conforti A; Bertaina A; Giorgiani G; Jol-van der Zijde CM; Zecca M; Le Blanc K; Frassoni F; Egeler RM; Fibbe WE; Lankester AC; Locatelli F
Article: STEM CELLS. 2013;31(8):1715-1725
Alterations in the Cellular Immune Compartment of Patients Treated with Third-Party Mesenchymal Stromal Cells Following Allogeneic Hematopoietic Stem Cell Transplantation
Jitschin R; Mougiakakos D; Von Bahr L; Voelkl S; Moll G; Ringden O; Kiessling R; Linder S; Le Blanc K
Article: JOURNAL OF INTERNAL MEDICINE. 2013;274(2):153-162
A prospective randomized toxicity study to compare reduced-intensity and myeloablative conditioning in patients with myeloid leukaemia undergoing allogeneic haematopoietic stem cell transplantation
Ringden O; Erkers T; Aschan J; Garming-Legert K; Le Blanc K; Hagglund H; Omazic B; Svenberg P; Dahllof G; Mattsson J; Ljungman P; Remberger M
Article: ONCOIMMUNOLOGY. 2013;2(7):e25009
Myeloid-derived suppressor cells in allogeneic hematopoietic stem cell transplantation A double-edged sword?
Le Blanc K; Jitschin R; Mougiakakos D
Article: LEUKEMIA. 2013;27(2):377-388
Immunosuppressive CD14⁺HLA-DR^low/neg IDO⁺ myeloid cells in patients following allogeneic hematopoietic stem cell transplantation
Mougiakakos D; Jitschin R; von Bahr L; Poschke I; Gary R; Sundberg B; Gerbitz A; Ljungman P; Le Blanc K
Article: PLOS ONE. 2013;8(1):e55319
Human Embryonic Stem Cell-Derived Mesenchymal Stroma Cells (hES-MSCs) Engraft In Vivo and Support Hematopoiesis without Suppressing Immune Function: Implications for Off-The Shelf ES-MSC Therapies
Li O; Tormin A; Sundberg B; Hyllner J; Le Blanc K; Scheding S
Article: PLOS ONE. 2013;8(1):e54952
Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures
Yu D; Jin C; Ramachandran M; Xu J; Nilsson B; Korsgren O; Le Blanc K; Uhrbom L; Forsberg-Nilsson K; Westermark B; Adamson R; Maitland N; Fan X; Essand M
Article: MEDICAL ONCOLOGY. 2012;29(4):2348-2358
Different impact of intermediate and unfavourable cytogenetics at the time of diagnosis on outcome of de novo AML after allo-SCT: a long-term retrospective analysis from a single institution
Nahi H; Remberger M; Machaczka M; Ungerstedt J; Mattson J; Ringden O; Le-Blanc K; Ljungman P; Hagglund H
Article: TRANSPLANTATION. 2012;94(10):1066-1074
Factors With an Impact on Chimerism Development and Long-Term Survival After Umbilical Cord Blood Transplantation
Berglund S; Le Blanc K; Remberger M; Gertow J; Uzunel M; Svenberg P; Winiarski J; Ljungman P; Ringden O; Uhlin M; Mattsson J
Article: STEM CELLS AND DEVELOPMENT. 2012;21(17):3147-3151
Treatment of Familial Hemophagocytic Lymphohistiocytosis with Third-Party Mesenchymal Stromal Cells
Mougiakakos D; Machaczka M; Jitschin R; Klimkowska M; Entesarian M; Bryceson YT; Henter J-I; Sander B; Le Blanc K
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2012;89(3):220-227
Treatment with mesenchymal stromal cells is a risk factor for pneumonia-related death after allogeneic hematopoietic stem cell transplantation
Forslow U; Blennow O; LeBlanc K; Ringden O; Gustafsson B; Mattsson J; Remberger M
Article: PEDIATRIC TRANSPLANTATION. 2012;16(6):E241-E245
Donor cell-derived acute myeloid leukemia after second allogenic cord blood transplantation in a patient with Fanconi anemia
Gustafsson B; Moell J; LeBlanc K; Barbany G; Soderhall S; Winiarski J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(31):25795-25807
Primary Mesenchymal Stem and Progenitor Cells from Bone Marrow Lack Expression of CD44 Protein
Qian H; Le Blanc K; Sigvardsson M
Article: STEM CELLS. 2012;30(7):1565-1574
Are Therapeutic Human Mesenchymal Stromal Cells Compatible with Human Blood?
Moll G; Rasmusson-Duprez I; von Bahr L; Connolly-andersen A-M; Elgue G; Funke L; Hamad OA; Lonnies H; Magnusson PU; Sanchez J; Teramura Y; Nilsson-Ekdahl K; Ringden O; Korsgren O; Nilsson B; Le Blanc K
Article: STEM CELLS. 2012;30(7):1575-1578
Analysis of Tissues Following Mesenchymal Stromal Cell Therapy in Humans Indicates Limited Long-Term Engraftment and No Ectopic Tissue Formation
von Bahr L; Batsis I; Moll G; Hagg M; Szakos A; Sundberg B; Uzunel M; Ringden O; Le Blanc K
Article: STEM CELLS AND DEVELOPMENT. 2012;21(9):1478-1487
Oral Mucosal Progenitor Cells Are Potently Immunosuppressive in a Dose-Independent Manner
Davies LC; Lonnies H; Locke M; Sundberg B; Rosendahl K; Gotherstrom C; Le Blanc K; Stephens P
Article: TISSUE ENGINEERING PART B-REVIEWS. 2012;18(2):101-115
Therapeutic Applications of Mesenchymal Stromal Cells: Paracrine Effects and Potential Improvements
Doorn J; Moll G; Le Blanc K; van Blitterswijk C; de Boer J
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2012;18(4):557-564
Long-Term Complications, Immunologic Effects, and Role of Passage for Outcome in Mesenchymal Stromal Cell Therapy
von Bahr L; Sundberg B; Lonnies L; Sander B; Karbach H; Hagglund H; Ljungman P; Gustafsson B; Karlsson H; Le Blanc K; Ringden O
Article: CELL TRANSPLANTATION. 2012;21(1):333-343
Targeted Intra-arterial Transplantation of Stem Cells to the Injured CNS Is More Effective Than Intravenous Administration: Engraftment Is Dependent on Cell Type and Adhesion Molecule Expression
Lundberg J; Sodersten E; Sundstrom E; Le Blanc K; Andersson T; Hermanson O; Holmin S
Journal article: LANCET. 2011;378(9808):1997-2004
Tracheobronchial transplantation with a stem-cell-seeded bioartificial nanocomposite: a proof-of-concept study (Publication with Expression of Concern. See vol. 387, pg. 1359, 2016) (Retracted article. See vol. 392, pg. 11, 2018)
Jungebluth P; Alici E; Baiguera S; Le Blanc K; Blomberg P; Bozoky B; Crowley C; Einarsson O; Grinnemo K-H; Gudbjartsson T; Le Guyader S; Henriksson G; Hermanson O; Juto JE; Leidner B; Lilja T; Liska J; Luedde T; Lundin V; Moll G; Nilsson B; Roderburg C; Stromblad S; Sutlu T; Teixeira AI; Watz E; Seifalian A; Macchiarini P
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2011;17(11):1688-1697
Improved Survival after Allogeneic Hematopoietic Stem Cell Transplantation in Recent Years. A Single-Center Study
Remberger M; Ackefors M; Berglund S; Blennow O; Dahllof G; Dlugosz A; Garming-Legert K; Gertow J; Gustafsson B; Hassan M; Hassan Z; Hauzenberger D; Hagglund H; Karlsson H; Klingspor L; Kumlien G; Le Blanc K; Ljungman P; Machaczka M; Malmberg K-J; Marschall H-U; Mattsson J; Olsson R; Omazic B; Sairafi D; Schaffer M; Svahn B-M; Svenberg P; Swartling L; Szakos A; Uhlin M; Uzunel M; Watz E; Wernerson A; Wikman A; Wikstrom A-C; Winiarski J; Ringden O
Article: LARYNGOSCOPE. 2011;121(10):2185-2190
Injection of Human Mesenchymal Stem Cells Improves Healing of Vocal Folds after Scar Excision-A Xenograft Analysis
Svensson B; Nagubothu SR; Cedervall J; Chan RW; Le Blanc K; Kimura M; Ahrlund-Richter L; Tolf A; Hertegard S
Article: PLOS ONE. 2011;6(7):e21703
Mesenchymal Stromal Cells Engage Complement and Complement Receptor Bearing Innate Effector Cells to Modulate Immune Responses
Moll G; Jitschin R; von Bahr L; Rasmusson-Duprez I; Sundberg B; Lonnies L; Elgue G; Nilsson-Ekdahl K; Mougiakakos D; Lambris JD; Ringden O; Le Blanc K; Nilsson B
Article: BLOOD. 2011;117(18):4826-4835
The impact of inflammatory licensing on heme oxygenase-1-mediated induction of regulatory T cells by human mesenchymal stem cells
Mougiakakos D; Jitschin R; Johansson CC; Okita R; Kiessling R; Le Blanc K
Article: JOURNAL OF IMMUNOTHERAPY. 2011;34(4):336-342
Multipotent Mesenchymal Stromal Cells Express FoxP3: A Marker for the Immunosuppressive Capacity?
Sundin M; D'Arcy P; Johansson CC; Barrett AJ; Loennies H; Sundberg B; Nava S; Kiessling R; Mougiakakos D; Le Blanc K
Article: CYTOTHERAPY. 2011;13(3):269-278
Fetal and adult multipotent mesenchymal stromal cells are killed by different pathways
Gotherstrom C; Lundqvist A; Duprez IR; Childs R; Berg L; le Blanc K
Article: BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY. 2011;24(1):65-72
Mesenchymal stem cells for treatment of acute and chronic graft-versus-host disease, tissue toxicity and hemorrhages
Ringden O; Le Blanc K
Article: BONE MARROW TRANSPLANTATION. 2011;46(2):200-207
Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation
Bernardo ME; Ball LM; Cometa AM; Roelofs H; Zecca M; Avanzini MA; Bertaina A; Vinti L; Lankester A; Maccario R; Ringden O; Le Blanc K; Egeler RM; Fibbe WE; Locatelli F
Journal article: BLOOD. 2010;116(21):2336
Early Intervention with Mesenchymal Stromal Cells for Refractory Grade III-IV Graft Versus Host Disease In Children Results In Excellent Long Term Outcome
Ball LM; Bernardo ME; Zwaginga JJ; van Tol M; Cometa A; Roelofs H; Giorgiani G; der Zijde CMJ-V; Avanzini MA; Le Blanc K; Bertaina A; Frassoni F; Fibbe WE; Ringden O; Egeler RM; Locatelli F; Lankester A
Journal article: BLOOD. 2010;116(21):3858
Human Embryonic Stem Cell-Derived Mesenchymal Stroma Cells (hES-MSC) Share Basic Properties with Bone Marrow MSC, They Have Potent Stroma Support Capacities but Lack Immune-Modulatory Function. Implications for off-the Shelf ES-MSC Therapies.
Li O; Tormin A; Brune JC; Sundberg B; Hyllner J; Le Blanc K; Scheding S
Journal article: ULTRASOUND IN OBSTETRICS & GYNECOLOGY. 2010;36(S1):132
OP27.07: Intrauterine transfusion (IUT) of mesenchymal stem cells in two fetuses with fractures: follow‐up to 3 and 4 years of age
Yamamoto M; Conget P; Anguita T; Allers C; Testart E; Castillo S; Gothestrom C; Le Blanc K; Crain C; Insunza A
Article: CYTOTHERAPY. 2010;12(5):576-578
Defining the risks of mesenchymal stromal cell therapy
Prockop DJ; Brenner M; Fibbe WE; Horwitz E; Le Blanc K; Phinney DG; Simmons PJ; Sensebe L; Keating A
Article: LARYNGOSCOPE. 2010;120(7):1370-1375
Injection of Human Mesenchymal Stem Cells Improves Healing of Scarred Vocal Folds: Analysis Using a Xenograft Model
Svensson B; Nagubothu RS; Cedervall J; Le Blanc K; Ahrlund-Richter L; Tolf A; Hertegard S
Journal article: BLOOD. 2009;114(22):4580
Human Mesenchymal Stem Cells Elicit Complement Activation in Human Blood.
Le Blanc K; Moll G; Rasmusson I; Ekdahl KN; Elgue G; Sundberg B; Nilsson B
Article: NEURORADIOLOGY. 2009;51(10):661-667
Endovascular transplantation of stem cells to the injured rat CNS
Lundberg J; Le Blanc K; Soderman M; Andersson T; Holmin S
Article: TRANSPLANT INFECTIOUS DISEASE. 2009;11(5):393-399
Targeted monitoring of patients at high risk of post-transplant lymphoproliferative disease by quantitative Epstein-Barr virus polymerase chain reaction
Omar H; Hagglund H; Gustafsson-Jernberg A; LeBlanc K; Mattsson J; Remberger M; Ringden O; Sparrelid E; Sundin M; Winiarski J; Yun Z; Ljungman P
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2009;15(9):1108-1115
Lymphocyte Recovery Is a Major Determinant of Outcome after Matched Unrelated Myeloablative Transplantation for Myelogenous Malignancies
Le Blanc K; Barrett AJ; Schaffer M; Hagglund H; Ljungman P; Ringden O; Remberger M
Article: JOURNAL OF IMMUNOTHERAPY. 2009;32(7):755-764
HSCT Recipients Have Specific Tolerance to MSC but not to the MSC Donor
Sundin M; Barrett AJ; Ringden O; Uzunel M; Lonnies H; Dackland A-L; Christensson B; Le Blanc K
Journal article: CYTOTHERAPY. 2009;11(6):674-675
Hematopoiesis does not always get support from MSC
Le Blanc K
Article: CYTOTHERAPY. 2009;11(2):129-136
Optimizing in vitro conditions for immunomodulation and expansion of mesenchymal stromal cells
Samuelsson H; Ringden O; Lonnies H; Le Blanc K
Journal article: BLOOD. 2008;112(11):4740
HLA Mismatched MSC Suppress T Lymphocyte Allo responses in Vitro and Do Not Induce Immunological Memory in Recipients of MSC Infusion
Sundin M; Barrett AJ; Ringdén O; Uzunel M; Lönnies H; Dackland Å-L; Christensson B; Le Blanc K
Journal article: BLOOD. 2008;112(11):4745
Persistence of Human Parvovirus B19 in Multipotent Mesenchymal Stromal Cells Expressing the Erythrocyte P antigen: Implications for Transplantation
Sundin M; Lindblom A; Örvell C; Barrett AJ; Sundberg B; Watz E; Wikman A; Broliden K; Le Blanc K
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2008;14(10):1172-1179
Persistence of human parvovirus B19 in multipotent mesenchymal stromal cells expressing the erythrocyte P antigen:: Implications for transplantation
Sundin M; Lindblom A; Orvell C; Barrett AJ; Sundberg B; Watz E; Wikman A; Broliden K; Le Blanc K
Article: BLOOD. 2008;112(3):532-541
Mesenchymal stem cells exert differential effects on alloantigen and virus-specific T-cell responses
Karlsson H; Samarasinghe S; Ball LM; Sundberg B; Lankester AC; Dazzi F; Uzunel M; Rao K; Veys P; Le Blanc K; Ringden O; Amrolia PJ
Article: BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY. 2008;21(2):165-176
Prophylaxis of acute GVHD: manipulate the graft or the environment?
Barrett AJ; Le Blanc K
Article: LANCET. 2008;371(9624):1579-1586
Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease:: a phase II study
LeBlanc K; Frassoni F; Ball L; Locatelli F; Roelofs H; Lewis I; Lanino E; Sundberg B; Bernardo ME; Remberger M; Dini G; Egeler RM; Bacigalupo A; Fibbe W; Ringden O
Article: BONE MARROW TRANSPLANTATION. 2008;41(4):399-405
Risk factors for acute graft-versus-host disease grades II-IV after reduced intensity conditioning allogeneic stem cell transplantation with unrelated donors -: a single centre study
Remberger M; Mattsson J; Hassan Z; Karlsson N; LeBlanc K; Omazic B; Okas M; Sairafi D; Ringden O
Article: CYTOTHERAPY. 2008;10(2):174-181
In vitro immunologic properties of human umbilical cord perivascular cells
Ennis J; Gotherstrom C; Le Blanc K; Davies JE
Article: CYTOTHERAPY. 2008;10(3):238-242
No increased trapping of multipotent mesenchymal stromal cells in bone marrow filters compared with other bone marrow cells
Sundin M; Remberger M; Lonnies H; Sundberg B; Ringden O; Le Blanc K
Article: LEUKEMIA. 2007;21(11):2271-2276
Tissue repair using allogeneic mesenchymal stem cells for hemorrhagic cystitis, pneumomediastinum and perforated colon
Ringden O; Uzunel M; Sundberg B; Lonnies L; Nava S; Gustafsson J; Henningsohn L; Le Blanc K
Article: TRANSPLANTATION. 2007;84(8):1055-1059
Generation of immunosuppressive mesenchymal stem cells in allogeneic human serum
Le Blanc K; Samuelsson H; Lönnies L; Sundin M; Ringdén O
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2007;82(4):887-893
Mesenchymal stem cells fail to trigger effector functions of cytotoxic T lymphocytes
Rasmusson I; Uhlin M; Le Blanc K; Levitsky V
Article: CLINICAL TRANSPLANTATION. 2007;21(5):659-667
Hemorrhagic cystitis:: a retrospective single-center survey
Hassan Z; Remberger M; Svenberg P; Elbander M; Omazic B; Mattsson J; Conrad R; Svahn B-M; Ahlgren A; Sairafi D; Aschan J; Le Blanc K; Barkholt L; Ringden O
Article: HAEMATOLOGICA. 2007;92(9):1208-1215
No alloantibodies against mesenchymal stromal cells, but presence of anti-fetal calf serum antibodies, after transplantation in allogeneic hematopoietic stem cell recipients
Sundin M; Ringden O; Sundberg B; Nava S; Gotherstrom C; Le Blanc K
Article: LEUKEMIA. 2007;21(8):1733-1738
Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cells
Le Blanc K; Samuelsson H; Gustafsson B; Remberger M; Sundberg B; Arvidson J; Ljungman P; Lonnies H; Nava S; Ringden O
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2007;65(4):336-343
Mesenchymal stem cells stimulate antibody secretion in human B cells
Rasmusson I; Le Blanc K; Sundberg B; Ringden O
Journal article: BLOOD. 2006;108(11):5304
Mesenchymal Stem Cells for Treatment of Severe Acute Graft-Versus-Host Disease.
Le Blanc K; Frassoni F; Ball L; Lanino E; Sundberg B; Lonnies L; Roelofs H; Dini G; Bacigalupo A; Locatelli F; Fibbe WF; Ringden O
Journal article: BLOOD. 2006;108(11):2918
Mesenchymal Stem Cells for Treatment of Severe Acute Graft-Versus-Host Disease.
Le Blanc K; Frassoni F; Ball L; Lanino E; Sundberg B; Lonnies H; Roelofs H; Dini G; Bacigalupo A; Locatelli F; Fibbe WF; Ringden O
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2006;135(3):367-373
Different outcome of allogeneic transplantation in myelofibrosis using conventional or reduced-intensity conditioning regimens
Merup M; Lazarevic V; Nahi H; Andreasson B; Malm C; Nilsson L; Brune M; LeBlanc K; Kutti J; Birgegard G
Article: ARTHRITIS & RHEUMATOLOGY. 2006;55(4):521-525
Stem cells and rheumatology: Update on adult stem cell therapy in autoimmune diseases
Tyndall A; Leblanc K
Article: HAEMATOLOGICA. 2006;91(8):1059-1067
The role of HLA mismatch, splenectomy and recipient Epstein-Barr virus seronegativity as risk factors in post-transplant lymphoproliferative disorder following allogeneic hematopoietic stem cell transplantation
Sundin M; Le Blanc K; Ringden O; Barkholt L; Omazic B; Lergin C; Levitsky V; Remberger M
Article: LARYNGOSCOPE. 2006;116(7):1248-1254
Viscoelastic and histologic properties in scarred rabbit vocal folds after mesenchymal stem cell injection
Hertegard S; Cedervall J; Svensson B; Forsberg K; Maurer FHJ; Vidovska D; Olivius P; Ahrlund-Richter L; Le Blanc K
Article: BONE MARROW TRANSPLANTATION. 2006;37(11):1051-1059
Mesenchymal stem cells are susceptible to human herpesviruses, but viral DNA cannot be detected in the healthy seropositive individual
Sundin M; Orvell C; Rasmusson I; Sundberg B; Ringden O; Le Blanc K
Article: TRANSPLANTATION. 2006;81(10):1390-1397
Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease
Ringden O; Uzunel M; Rasmusson I; Remberger M; Sundberg B; Lonnies H; Marschall H-U; Dlugosz A; Szakos A; Hassan Z; Omazic B; Aschan J; Barkholt L; Le Blanc K
Article: TRANSPLANTATION. 2006;81(5):718-725
Allogeneic hematopoietic stem cell transplantation for inherited disorders:: Experience in a single center
Ringdén O; Remberger M; Svahn BM; Barkholt L; Mattsson J; Aschan J; Le Blanc K; Gustafsson B; Hassan Z; Omazic B; Svenberg P; Solders G; von Döbeln U; Winiarski J; Ljungman P; Malm G
Article: ANNALS OF MEDICINE. 2006;38(2):144-153
Human mesenchymal stem cells do not differentiate into cardiomyocytes in a cardiac ischemic xenomodel
Grinnemo KH; Månsson-Broberg A; Leblanc K; Corbascio M; Wärdell E; Siddiqui AJ; Hao XJ; Sylvén C; Dellgren G
Article: CYTOTHERAPY. 2006;8(6):559-561
Mesenchymal stromal cells: tissue repair and immune modulation
Le Blanc K
Article: CYTOTHERAPY. 2006;8(4):315-317
Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
Dominici M; Le Blanc K; Mueller I; Slaper-Cortenbach I; Marini FC; Krause DS; Deans RJ; Keating A; Prockop DJ; Horwitz EM
Article: INTERNATIONAL JOURNAL OF OBESITY. 2005;29(12):1413-1421
Differential function of the α2A-adrenoceptor and phosphodiesterase-3B in human adipocytes of different origin
Dicker A; Kaaman M; van Harmelen V; Åström G; Blanc KL; Rydén M
Journal article: BLOOD. 2005;106(11):143
Mesenchymal Stem Cells for Treatment of Severe Acute and Extensive Chronic Graft-Versus-Host Disease.
Le Blanc K; Frassoni F; Ball L; Uzunel M; Lanini E; Sundberg B; Lonnies H; Dini G; Bacigalupo A; Locatelli F; Fibbe WE; Ringden OTH
Journal article: BLOOD. 2005;106(11):2911
Transplantation of Haplo-Identical Bone Marrow-Derived Mesenchymal Stem Cells Together with Hematopoietic Stem Cells To Promote Engraftment in Children. A Phase I/II Multicenter Study.
van Velzen-Ball LM; Le Blanc K; Lankester AC; Roelofs H; Egeler M; Frassoni F; Ringdén O; Fibbe WE
Article: EXPERIMENTAL CELL RESEARCH. 2005;308(2):283-290
Functional studies of mesenchymal stem cells derived from adult human adipose tissue
Dicker A; Le Blanc K; Åström G; van Harmelen V; Götherström C; Blomqvist L; Arner P; Rydén M
Article: HAEMATOLOGICA. 2005;90(8):1017-1026
Difference in gene expression between human fetal liver and adult bone marrow mesenchymal stem cells
Gotherstrom C; West A; Liden J; Uzunel M; Lahesmaa R; Le Blanc K
Article: TRANSPLANTATION. 2005;79(11):1607-1614
Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta
Le Blanc K; Götherström C; Ringdén O; Hassan M; McMahon R; Horwitz E; Anneren G; Axelsson O; Nunn J; Ewald U; Nordén-Lindeberg S; Jansson M; Dalton A; Åström E; Westgren M
Article: EXPERIMENTAL CELL RESEARCH. 2005;305(1):33-41
Mesenchymal stem cells inhibit lymphocyte proliferation by mitogens and alloantigens by different mechanisms
Rasmusson I; Ringdén O; Sundberg B; Le Blanc K
Article: CANCER RESEARCH. 2005;65(6):2207-2215
Cancer/testis antigen expression in human mesenchymal stem cells:: Down-regulation of SSX impairs cell migration and matrix metalloproteinase 2 expression
Cronwright G; Le Blanc K; Götherström C; Darcy P; Ehnman M; Brodin B
Article: CYTOTHERAPY. 2005;7(5):393-395
Clarification of the nomenclature for MSC: The international society for cellular therapy position statement
Horwitz EM; Le Blanc K; Dominici M; Mueller I; Slaper-Cortenbach I; Marini FC; Deans RJ; Krause DS; Keating A
Article: CYTOTHERAPY. 2005;7(1):36-45
Mesenchymal stem cells: progress toward promise
Le Blanc K; Pittenger MF
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2004;10(12):877-882
Allogenic stem cell transplantation for nonmalignant disorders using matched unrelated donors
Svenberg P; Remberger M; Svennilson J; Mattsson J; Leblanc K; Gustafsson B; Aschan J; Barkholt L; Winiarski J; Ljungman P; Ringdén O
Article: TRANSPLANTATION. 2004;78(7):1014-1020
A comparison of nonmyeloablative and reduced-intensity conditioning for allogeneic stem-cell transplantation
Le Blanc K; Remberger M; Uzunel M; Mansson J; Barkholt L; Ringdén O
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;60(3):307-315
Mesenchymal stem cells inhibit the expression of CD25 (interleukin-2 receptor) and CD38 on phytohaemagglutinin-activated lymphocytes
Le Blanc K; Rasmusson I; Götherström C; Seidel C; Sundberg B; Sundin M; Rosendahl K; Tammik C; Ringdén O
Journal article: BONE MARROW TRANSPLANTATION. 2004;33(11):1167
Erratum: Immunomodulatory effects of human foetal liver-derived mesenchymal stem cells
Götherström C; Ringdén O; Westgren M; Tammik C; Le Blanc K
Article: LANCET. 2004;363(9419):1439-1441
Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
Le Blanc K; Rasmusson I; Sundberg B; Götherström C; Hassan M; Uzunel M; Ringdén O
Article: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 2004;127(5):1293-1300
Xenoreactivity and engraftment of human mesenchymal stem cells transplanted into infarcted rat myocardium
Grinnemo KH; Månsson A; Dellgren G; Klingberg D; Wardell E; Drvota V; Tammik C; Holgersson J; Ringdén O; Sylvén C; Le Blanc K
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2004;10(3):195-203
Graft-versus-Host disease is associated with a lower relapse incidence after hematopoietic stem cell transplantation in patients with acute lymphoblastic leukemia
Nordlander A; Mattsson J; Ringdén O; Leblanc K; Gustafsson B; Ljungman P; Svenberg P; Svennilson J; Remberger M
Article: JOURNAL OF CLINICAL ONCOLOGY. 2004;22(3):416-423
Treatment with granulocyte colony-stimulating factor after allogeneic bone marrow transplantation for acute leukemia increases the risk of graft-versus-host disease and death:: A study from the acute leukemia working party of the European Group for Blood and Marrow Transplantation
Ringdén O; Labopin M; Gorin NC; Le Blanc K; Rocha V; Gluckman E; Reiffers J; Arcese W; Vossen JM; Jouet JP; Cordonnier C; Frassoni F
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2004;10(2):128-134
Which donor should be chosen for hematopoietic stem cell transplantation among unrelated HLA-A, -B, and-DRB1 genomically identical volunteers?
Ringdén O; Schaffer M; Le Blanc AA; Persson U; Hauzenberger D; Abedi MR; Olerup O; Ljungman P; Remberger M
Article: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2004;190(1):239-245
Immunologic properties of human fetal mesenchymal stem cells
Götherström C; Ringdén O; Tammik C; Zetterberg E; Westgren M; Le Blanc K
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003;311(2):391-397
Functional characterization of human mesenchymal stem cell-derived adipocytes
Rydén M; Dicker A; Götherström C; Åström G; Tammik C; Arner P; Le Blanc K
Article: TRANSPLANTATION. 2003;76(8):1208-1213
Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells
Rasmusson I; Ringdén O; Sundberg B; Le Blanc K
Article: EXPERIMENTAL HEMATOLOGY. 2003;31(10):890-896
HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells
Le Blanc K; Tammik C; Rosendahl K; Zetterberg E; Ringdén O
Article: HAEMATOLOGICA. 2003;88(9):1044-1052
A low body mass index is correlated with poor survival after allogeneic stem cell transplantation
Le Blanc K; Ringdén O; Remberger M
Article: BONE MARROW TRANSPLANTATION. 2003;32(3):265-272
Immunomodulatory effects of human foetal liver-derived mesenchymal stem cells
Götherström C; Ringdén O; Westgren M; Tammik C; Le Blanc K
Article: BONE MARROW TRANSPLANTATION. 2003;32(2):217-223
G-CSF given after haematopoietic stem cell transplantation using HLA-identical sibling donors is associated to a higher incidence of acute GVHD II-IV
Remberger M; Naseh N; Aschan J; Barkholt L; LeBlanc K; Svennberg P; Ringdén O
Article: CYTOTHERAPY. 2003;5(6):485-489
Immunomodulatory effects of fetal and adult mesenchymal stem cells
Le Blanc K
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2003;57(1):11-20
Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex
Le Blanc K; Tammik L; Sundberg B; Haynesworth SE; Ringdén O
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2000;65(5):322-330
Defective platelet aggregation in polycythaemia vera is not caused by impaired calcium signaling, phospholipase D activation or decreased amounts of focal adhesion proteins
Le Blanc K; Berg A; Palmblad J; Samuelsson J
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2000;108(1):80-85
Marked heterogeneity in protein levels and functional integrity of the thrombopoietin receptor c-mpl in polycythaemia vera
Le Blanc K; Andersson P; Samuelsson J
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1997;59(5):310-317
No evidence for an altered mRNA expression or protein level of haematopoietic cell phosphatase in CD34(+) bone marrow progenitor cells or mature peripheral blood cells in polycythaemia vera
Andersson P; LeBlanc K; Eriksson BA; Samuelsson J
Article: BIOCHEMICAL PHARMACOLOGY. 1995;49(11):1577-1582
1-O-HEXADECYL-2-METOXY-GLYCERO-3-PHOSPHATIDYLCHOLINE - A METHOXY ETHER LIPID INHIBITING PLATELET-ACTIVATING FACTOR-INDUCED PLATELET-AGGREGATION AND NEUTROPHIL OXIDATIVE-METABOLISM
LEBLANC K; SAMUELSSON J; BROHULT J; BERG A; PALMBLAD J
Journal article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1994;53(3):145-149
STIMULUS-SPECIFIC DEFECT IN PLATELET-AGGREGATION IN POLYCYTHEMIA-VERA
LEBLANC K; BERG A; PALMBLAD J; SAMUELSSON J
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Professor/Specialistläkare, Laboratoriemedicin, Karolinska Institutet, 2007-

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Docent, Hematologi, Karolinska Institutet, 2004
MEDICINE DOKTORSEXAMEN, Institutionen för medicin, Huddinge, Karolinska Institutet, 1999
Läkarexamen, Karolinska Institutet, 1993

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