Karolina Kauppi
Senior Forskare
E-postadress: karolina.kauppi@ki.se
Besöksadress: Nobels väg 12a, 17165 Solna
Postadress: C8 Medicinsk epidemiologi och biostatistik, C8 MEB Lichtenstein, 171 77 Stockholm
Om mig
- I min forskning studerar jag genetiska faktorer som påverkar människors
kognitiva förmåga i åldrandet och även vid psykiatriska sjukdomar. För
mer info, se denna sida på engelska.
PhD in physiology (neuroscience and genetics), Umeå Unversity, 2013.
MSc in Biomedicine, Umeå University, 2008.
*Postdoctoral training: *
Oslo University, 2013-2015
University of California San Diego, 2015-2017
Artiklar
- Journal article: ALZHEIMERS RESEARCH & THERAPY. 2024;16(1):39Hackenhaar FS; Josefsson M; Adolfsson AN; Landfors M; Kauppi K; Hultdin M; Adolfsson R; Degerman S; Pudas S
- Article: JOURNAL OF ALZHEIMERS DISEASE. 2023;94(4):1443-1464Hackenhaar FS; Josefsson M; Adolfsson AN; Landfors M; Kauppi K; Porter T; Milicic L; Laws SM; Hultdin M; Adolfsson R; Degerman S; Pudas S
- Article: NEUROBIOLOGY OF AGING. 2023;126:103-112Supiyev A; Karlsson R; Wang Y; Koch E; Hagg S; Kauppi K
- Article: SCIENTIFIC REPORTS. 2023;13(1):8433Haglin S; Koch E; Hackenhaar FS; Nyberg L; Kauppi K
- Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2023;32(4):446-454Koch E; Johnell K; Kauppi K
- Article: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 2023;120:110637Koch E; Kauppi K; Chen C-H
- Article: GENES. 2022;13(3):412Koch E; Nyberg L; Lundquist A; Kauppi K
- Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):520Koch E; Nyberg L; Lundquist A; Pudas S; Adolfsson R; Kauppi K
- Article: ALZHEIMERS RESEARCH & THERAPY. 2021;13(1):130Hackenhaar FS; Josefsson M; Adolfsson AN; Landfors M; Kauppi K; Hultdin M; Adolfsson R; Degerman S; Pudas S
- Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2021;76(6):955-963Pudas S; Josefsson M; Adolfsson AN; Landfors M; Kauppi K; Veng-Taasti LM; Hultdin M; Adolfsson R; Degerman S
- Article: SCHIZOPHRENIA RESEARCH. 2020;222:167-174Koch E; Rosenthal B; Lundquist A; Chen C-H; Kauppi K
- Article: TRANSLATIONAL PSYCHIATRY. 2020;10(1):250Kauppi K; Ronnlund M; Adolfsson AN; Pudas S; Adolfsson R
- Article: NEUROBIOLOGY OF AGING. 2019;84:243.e1-243.e9Lo M-T; Kauppi K; Fan C-C; Sanyal N; Reas ET; Sundar VS; Lee W-C; Desikan RS; McEvoy LK; Chen C-H
- Article: BRAIN. 2019;142(2):460-470Tan CH; Bonham LW; Fan CC; Mormino EC; Sugrue LP; Broce IJ; Hess CP; Yokoyama JS; Rabinovici GD; Miller BL; Yaffe K; Schellenberg GD; Kauppi K; Holland D; McEvoy LK; Kukull WA; Tosun D; Weiner MW; Sperling RA; Bennett DA; Hyman BT; Andreassen OA; Dale AM; Desikan RS
- Article: BIOINFORMATICS. 2019;35(1):1-11Sanyal N; Lo M-T; Kauppi K; Djurovic S; Andreassen OA; Johnson VE; Chen C-H
- Article: AMERICAN JOURNAL OF PSYCHIATRY. 2018;175(7):674-682Kauppi K; Rosenthal SB; Lo M-T; Sanyal N; Jiang M; Abagyan R; McEvoy LK; Andreassen OA; Chen C-H
- Article: FRONTIERS IN NEUROSCIENCE. 2018;12:260Kauppi K; Fan CC; McEvoy LK; Holland D; Tan CH; Chen C-H; Andreassen OA; Desikan RS; Dale AM
- Article: ACTA NEUROPATHOLOGICA. 2018;135(1):85-93Tan CH; Fan CC; Mormino EC; Sugrue LP; Broce IJ; Hess CP; Dillon WP; Bonham LW; Yokoyama JS; Karch CM; Brewer JB; Rabinovici GD; Miller BL; Schellenberg GD; Kauppi K; Feldman HA; Holland D; McEvoy LK; Hyman BT; Bennett DA; Andreassen OA; Dale AM; Desikan RS
- Article: SCIENTIFIC REPORTS. 2017;7(1):15736Chen C-H; Wang Y; Lo M-T; Schork A; Fan C-C; Holland D; Kauppi K; Smeland OB; Djurovic S; Sanyal N; Hibar DP; Thompson PM; Thompson WK; Andreassen OA; Dale AM
- Article: HUMAN MOLECULAR GENETICS. 2017;26(22):4530-4539Lo M-T; Wang Y; Kauppi K; Sanyal N; Fan C-C; Smeland OB; Schork A; Holland D; Hinds DA; Tung JY; Andreassen OA; Dale AM; Chen C-H
- Article: JAMA PSYCHIATRY. 2017;74(10):1065-1075Smeland OB; Frei O; Kauppi K; Hill WD; Li W; Wang Y; Krull F; Bettella F; Eriksen JA; Witoelar A; Davies G; Fan CC; Thompson WK; Lam M; Lencz T; Chen C-H; Ueland T; Jonsson EG; Djurovic S; Deary IJ; Dale AM; Andreassen OA
- Article: ANNALS OF NEUROLOGY. 2017;82(3):484-488Tan CH; Hyman BT; Tan JJX; Hess CP; Dillon WP; Schellenberg GD; Besser LM; Kukull WA; Kauppi K; McEvoy LK; Andreassen OA; Dale AM; Fan CC; Desikan RS
- Article: PLOS MEDICINE. 2017;14(3):e1002258Desikan RS; Fan CC; Wang Y; Schork AJ; Cabra HJI; Cupples LA; Thompson WK; Besser L; Kukull WA; Holland D; Chen C-H; Brewer JB; Karow DS; Kauppi K; Witoelar A; Karch CM; Bonham LW; Yokoyama JS; Rosen HJ; Miller BL; Dillon WP; Wilson DM; Hess CP; Pericak-Vance M; Haines JL; Farrer LA; Mayeux R; Hardy J; Goate AM; Hyman BT; Schellenberg GD; McEvoy LK; Andreassen OA; Dale AM
- Article: BRAIN BEHAVIOR AND IMMUNITY. 2017;61:209-216Athanasiu L; Giddaluru S; Fernandes C; Christoforou A; Reinvang I; Lundervold AJ; Nilsson L-G; Kauppi K; Adolfsson R; Eriksson E; Sundet K; Djurovic S; Espeseth T; Nyberg L; Steen VM; Andreassen OA; Le Hellard S
- Article: PSYCHOLOGICAL MEDICINE. 2017;47(4):669-679Aas M; Kauppi K; Brandt CL; Tesli M; Kaufmann T; Steen NE; Agartz I; Westlye LT; Andreassen OA; Melle I
- Article: NEUROIMAGE. 2017;147:243-252Kaufmann T; Alnaes D; Brandt CL; Nhat TD; Kauppi K; Bettella F; Lagerberg TV; Berg AO; Djurovic S; Agartz I; Melle IS; Ueland T; Andreassen OA; Westlye LT
- Article: NATURE GENETICS. 2017;49(1):152-156Lo M-T; Hinds DA; Tung JY; Franz C; Fan C-C; Wang Y; Smeland OB; Schork A; Holland D; Kauppi K; Sanyal N; Escott-Price V; Smith DJ; O'Donovan M; Stefansson H; Bjornsdottir G; Thorgeirsson TE; Stefansson K; McEvoy LK; Dale AM; Andreassen OA; Chen C-H
- Article: PLOS ONE. 2015;10(7):e0134202Tesli M; Kauppi K; Bettella F; Brandt CL; Kaufmann T; Espeseth T; Mattingsdal M; Agartz I; Melle I; Djurovic S; Westlye LT; Andreassen OA
- Article: SCHIZOPHRENIA BULLETIN. 2015;41(3):736-743Kauppi K; Westlye LT; Tesli M; Bettella F; Brandt CL; Mattingsdal M; Ueland T; Espeseth T; Agartz I; Melle I; Djurovic S; Andreassen OA
- Article: PSYCHIATRY RESEARCH. 2014;222(1-2):60-66Fernandes CPD; Westlye LT; Giddaluru S; Christoforou A; Kauppi K; Adolfsson R; Nilsson L-G; Nyberg L; Lundervold AJ; Reinvang I; Steen VM; Le Hellard S; Espeseth T
- Article: NEUROIMAGE. 2014;89:306-313Kauppi K; Nilsson L-G; Persson J; Nyberg L
- Article: JOURNAL OF COGNITIVE NEUROSCIENCE. 2014;26(4):746-754Nyberg L; Andersson M; Kauppi K; Lundquist A; Persson J; Pudas S; Nilsson L-G
- Article: NEUROPSYCHOLOGIA. 2013;51(12):2462-2468Kauppi K; Nilsson L-G; Adolfsson R; Lundquist A; Eriksson E; Nyberg L
- Article: CEREBRAL CORTEX. 2012;22(10):2297-2304Persson J; Pudas S; Lind J; Kauppi K; Nilsson L-G; Nyberg L
- Article: JOURNAL OF NEUROSCIENCE. 2011;31(40):14218-14222Kauppi K; Nilsson L-G; Adolfsson R; Eriksson E; Nyberg L
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(52):22682-22686Nyberg L; Salami A; Andersson M; Eriksson J; Kalpouzos G; Kauppi K; Lind J; Pudas S; Persson J; Nilsson L-G
- Article: NEUROIMAGE. 2010;52(2):686-698Salami A; Eriksson J; Kompus K; Habib R; Kauppi K; Nyberg L
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Alla övriga publikationer
- Review: AGEING RESEARCH REVIEWS. 2020;64:101184Nyberg L; Boraxbekk C-J; Sorman DE; Hansson P; Herlitz A; Kauppi K; Ljungberg JK; Lovheim H; Lundquist A; Adolfsson AN; Oudin A; Pudas S; Ronnlund M; Stiernstedt M; Sundstrom A; Adolfsson R
Forskningsbidrag
- Swedish Research Council1 January 2023 - 31 December 2025The aim of this 4-year project is to map the genetic heterogeneities of Alzheimer’s Disease (AD), to accelerate the development of personalized treatments. A novel approach will be used to estimate an individual’s genetic risk load in key disease pathways, such as immune-system related pathways, by incorporating knowledge about gene expression, interactions among gene products etc. We will study how specific gene pathways influence AD risk and disease related endophenotypes, and their interplay with two major inherited risk factors: sex and the high-penetrance APOE ε4 allele. This will be possible by using data from two deeply phenotyped longitudinal cohorts on aging, Betula and SATSA, as well as large-scale data from the IGEMS consortia and the UK Biobank. We will focus on the following outcomes: AD risk, cognitive ability, brain atrophy, and plasma-based biomarkers of AD pathology (tau) and chronic inflammation. Finally, we will identify existing drugs with a genetic link to AD, as potential candidates for drug-repurposing, with focus on drugs where an epidemiological link to AD has been suggested (e.g. anti-inflammatories). Results from this project is expected to reveal differences in the pathophysiological mechanisms of AD among individuals with different inherited risk profiles. This will allow to perform clinical trials of drugs designed to target a specific pathway in a limited group of individuals where this pathway is most likely to be disrupted.
- Swedish Research Council1 January 2018 - 31 December 2021
- Swedish Research Council1 January 2015 - 31 December 2017