Karolina Kauppi

Om mig
Publikationer
Forskningsbidrag
Populärvetenskap och samverkan

Om mig

I min forskning studerar jag genetiska faktorer som påverkar människors
kognitiva förmåga i åldrandet och även vid psykiatriska sjukdomar. För
mer info, se denna sida på engelska.
PhD in physiology (neuroscience and genetics), Umeå Unversity, 2013.
MSc in Biomedicine, Umeå University, 2008.
*Postdoctoral training: *
Oslo University, 2013-2015
University of California San Diego, 2015-2017

Artiklar

Article: JOURNAL OF ALZHEIMERS DISEASE. 2023;94(4):1443-1464

Sixteen-Year Longitudinal Evaluation of Blood-Based DNA Methylation Biomarkers for Early Prediction of Alzheimer's Disease

Hackenhaar FS; Josefsson M; Adolfsson AN; Landfors M; Kauppi K; Porter T; Milicic L; Laws SM; Hultdin M; Adolfsson R; Degerman S; Pudas S
Article: NEUROBIOLOGY OF AGING. 2023;126:103-112

Independent role of Alzheimer?s disease genetics and C-reactive protein on cognitive ability in aging

Supiyev A; Karlsson R; Wang Y; Koch E; Hagg S; Kauppi K
Article: SCIENTIFIC REPORTS. 2023;13(1):8433

APOE e4, but not polygenic Alzheimer's disease risk, is related to longitudinal decrease in hippocampal brain activity in non-demented individuals

Haglin S; Koch E; Hackenhaar FS; Nyberg L; Kauppi K
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2023;32(4):446-454

Longitudinal effects of using and discontinuing central nervous system medications on cognitive functioning

Koch E; Johnell K; Kauppi K
Article: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 2023;120:110637

Candidates for drug repurposing to address the cognitive symptoms in schizophrenia

Koch E; Kauppi K; Chen C-H
Article: GENES. 2022;13(3):412

Polygenic Risk for Schizophrenia Has Sex-Specific Effects on Brain Activity during Memory Processing in Healthy Individuals

Koch E; Nyberg L; Lundquist A; Kauppi K
Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):520

Sex-specific effects of polygenic risk for schizophrenia on lifespan cognitive functioning in healthy individuals

Koch E; Nyberg L; Lundquist A; Pudas S; Adolfsson R; Kauppi K
Article: ALZHEIMERS RESEARCH & THERAPY. 2021;13(1):130

Short leukocyte telomeres predict 25-year Alzheimer's disease incidence in non-APOE ε4-carriers

Hackenhaar FS; Josefsson M; Adolfsson AN; Landfors M; Kauppi K; Hultdin M; Adolfsson R; Degerman S; Pudas S
Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2021;76(6):955-963

Short Leukocyte Telomeres, But Not Telomere Attrition Rates, Predict Memory Decline in the 20-Year Longitudinal Betula Study

Pudas S; Josefsson M; Adolfsson AN; Landfors M; Kauppi K; Veng-Taasti LM; Hultdin M; Adolfsson R; Degerman S
Article: SCHIZOPHRENIA RESEARCH. 2020;222:167-174

Interactome overlap between schizophrenia and cognition

Koch E; Rosenthal B; Lundquist A; Chen C-H; Kauppi K
Article: TRANSLATIONAL PSYCHIATRY. 2020;10(1):250

Effects of polygenic risk for Alzheimer's disease on rate of cognitive decline in normal aging

Kauppi K; Ronnlund M; Adolfsson AN; Pudas S; Adolfsson R
Article: NEUROBIOLOGY OF AGING. 2019;84:243.e1-243.e9

Identification of genetic heterogeneity of Alzheimer's disease across age

Lo M-T; Kauppi K; Fan C-C; Sanyal N; Reas ET; Sundar VS; Lee W-C; Desikan RS; McEvoy LK; Chen C-H
Article: BRAIN. 2019;142(2):460-470

Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration

Tan CH; Bonham LW; Fan CC; Mormino EC; Sugrue LP; Broce IJ; Hess CP; Yokoyama JS; Rabinovici GD; Miller BL; Yaffe K; Schellenberg GD; Kauppi K; Holland D; McEvoy LK; Kukull WA; Tosun D; Weiner MW; Sperling RA; Bennett DA; Hyman BT; Andreassen OA; Dale AM; Desikan RS
Article: BIOINFORMATICS. 2019;35(1):1-11

GWASinlps: non-local prior based iterative SNP selection tool for genome-wide association studies

Sanyal N; Lo M-T; Kauppi K; Djurovic S; Andreassen OA; Johnson VE; Chen C-H
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2018;175(7):674-682

Revisiting Antipsychotic Drug Actions Through Gene Networks Associated With Schizophrenia

Kauppi K; Rosenthal SB; Lo M-T; Sanyal N; Jiang M; Abagyan R; McEvoy LK; Andreassen OA; Chen C-H
Article: FRONTIERS IN NEUROSCIENCE. 2018;12:260

Combining Polygenic Hazard Score With Volumetric MRI and Cognitive Measures Improves Prediction of Progression From Mild Cognitive Impairment to Alzheimer's Disease

Kauppi K; Fan CC; McEvoy LK; Holland D; Tan CH; Chen C-H; Andreassen OA; Desikan RS; Dale AM
Article: ACTA NEUROPATHOLOGICA. 2018;135(1):85-93

Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition

Tan CH; Fan CC; Mormino EC; Sugrue LP; Broce IJ; Hess CP; Dillon WP; Bonham LW; Yokoyama JS; Karch CM; Brewer JB; Rabinovici GD; Miller BL; Schellenberg GD; Kauppi K; Feldman HA; Holland D; McEvoy LK; Hyman BT; Bennett DA; Andreassen OA; Dale AM; Desikan RS
Article: SCIENTIFIC REPORTS. 2017;7(1):15736

Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure

Chen C-H; Wang Y; Lo M-T; Schork A; Fan C-C; Holland D; Kauppi K; Smeland OB; Djurovic S; Sanyal N; Hibar DP; Thompson PM; Thompson WK; Andreassen OA; Dale AM
Article: HUMAN MOLECULAR GENETICS. 2017;26(22):4530-4539

Modeling prior information of common genetic variants improves gene discovery for neuroticism

Lo M-T; Wang Y; Kauppi K; Sanyal N; Fan C-C; Smeland OB; Schork A; Holland D; Hinds DA; Tung JY; Andreassen OA; Dale AM; Chen C-H
Article: JAMA PSYCHIATRY. 2017;74(10):1065-1075

Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function

Smeland OB; Frei O; Kauppi K; Hill WD; Li W; Wang Y; Krull F; Bettella F; Eriksen JA; Witoelar A; Davies G; Fan CC; Thompson WK; Lam M; Lencz T; Chen C-H; Ueland T; Jonsson EG; Djurovic S; Deary IJ; Dale AM; Andreassen OA
Article: ANNALS OF NEUROLOGY. 2017;82(3):484-488

Polygenic Hazard Scores in Preclinical Alzheimer Disease

Tan CH; Hyman BT; Tan JJX; Hess CP; Dillon WP; Schellenberg GD; Besser LM; Kukull WA; Kauppi K; McEvoy LK; Andreassen OA; Dale AM; Fan CC; Desikan RS
Article: BRAIN BEHAVIOR AND IMMUNITY. 2017;61:209-216

A genetic association study of CSMD1 and CSMD2 with cognitive function

Athanasiu L; Giddaluru S; Fernandes C; Christoforou A; Reinvang I; Lundervold AJ; Nilsson L-G; Kauppi K; Adolfsson R; Eriksson E; Sundet K; Djurovic S; Espeseth T; Nyberg L; Steen VM; Andreassen OA; Le Hellard S
Article: PSYCHOLOGICAL MEDICINE. 2017;47(4):669-679

Childhood trauma is associated with increased brain responses to emotionally negative as compared with positive faces in patients with psychotic disorders

Aas M; Kauppi K; Brandt CL; Tesli M; Kaufmann T; Steen NE; Agartz I; Westlye LT; Andreassen OA; Melle I
Article: PLOS MEDICINE. 2017;14(3):e1002258

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

Desikan RS; Fan CC; Wang Y; Schork AJ; Cabra HJI; Cupples LA; Thompson WK; Besser L; Kukull WA; Holland D; Chen C-H; Brewer JB; Karow DS; Kauppi K; Witoelar A; Karch CM; Bonham LW; Yokoyama JS; Rosen HJ; Miller BL; Dillon WP; Wilson DM; Hess CP; Pericak-Vance M; Haines JL; Farrer LA; Mayeux R; Hardy J; Goate AM; Hyman BT; Schellenberg GD; McEvoy LK; Andreassen OA; Dale AM
Article: NEUROIMAGE. 2017;147:243-252

Task modulations and clinical manifestations in the brain functional connectome in 1615 fMRI datasets

Kaufmann T; Alnaes D; Brandt CL; Nhat TD; Kauppi K; Bettella F; Lagerberg TV; Berg AO; Djurovic S; Agartz I; Melle IS; Ueland T; Andreassen OA; Westlye LT
Article: NATURE GENETICS. 2017;49(1):152-156

Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders

Lo M-T; Hinds DA; Tung JY; Franz C; Fan C-C; Wang Y; Smeland OB; Schork A; Holland D; Kauppi K; Sanyal N; Escott-Price V; Smith DJ; O'Donovan M; Stefansson H; Bjornsdottir G; Thorgeirsson TE; Stefansson K; McEvoy LK; Dale AM; Andreassen OA; Chen C-H
Article: SCHIZOPHRENIA BULLETIN. 2015;41(3):736-743

Polygenic Risk for Schizophrenia Associated With Working Memory-related Prefrontal Brain Activation in Patients With Schizophrenia and Healthy Controls

Kauppi K; Westlye LT; Tesli M; Bettella F; Brandt CL; Mattingsdal M; Ueland T; Espeseth T; Agartz I; Melle I; Djurovic S; Andreassen OA
Article: PLOS ONE. 2015;10(7):e0134202

Altered Brain Activation during Emotional Face Processing in Relation to Both Diagnosis and Polygenic Risk of Bipolar Disorder

Tesli M; Kauppi K; Bettella F; Brandt CL; Kaufmann T; Espeseth T; Mattingsdal M; Agartz I; Melle I; Djurovic S; Westlye LT; Andreassen OA
Article: PSYCHIATRY RESEARCH. 2014;222(1-2):60-66

Lack of association of the rs1344706 ZNF804A variant with cognitive functions and DTI indices of white matter microstructure in two independent healthy populations

Fernandes CPD; Westlye LT; Giddaluru S; Christoforou A; Kauppi K; Adolfsson R; Nilsson L-G; Nyberg L; Lundervold AJ; Reinvang I; Steen VM; Le Hellard S; Espeseth T
Article: NEUROIMAGE. 2014;89:306-313

Additive genetic effect of APOE and BDNF on hippocampus activity

Kauppi K; Nilsson L-G; Persson J; Nyberg L
Article: JOURNAL OF COGNITIVE NEUROSCIENCE. 2014;26(4):746-754

Age-related and Genetic Modulation of Frontal Cortex Efficiency

Nyberg L; Andersson M; Kauppi K; Lundquist A; Persson J; Pudas S; Nilsson L-G
Article: NEUROPSYCHOLOGIA. 2013;51(12):2462-2468

Decreased medial temporal lobe activation in BDNF ⁶⁶Met allele carriers during memory encoding

Kauppi K; Nilsson L-G; Adolfsson R; Lundquist A; Eriksson E; Nyberg L
Article: CEREBRAL CORTEX. 2012;22(10):2297-2304

Longitudinal Structure-Function Correlates in Elderly Reveal MTL Dysfunction with Cognitive Decline

Persson J; Pudas S; Lind J; Kauppi K; Nilsson L-G; Nyberg L
Article: JOURNAL OF NEUROSCIENCE. 2011;31(40):14218-14222

KIBRA Polymorphism Is Related to Enhanced Memory and Elevated Hippocampal Processing

Kauppi K; Nilsson L-G; Adolfsson R; Eriksson E; Nyberg L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(52):22682-22686

Longitudinal evidence for diminished frontal cortex function in aging

Nyberg L; Salami A; Andersson M; Eriksson J; Kalpouzos G; Kauppi K; Lind J; Pudas S; Persson J; Nilsson L-G
Article: NEUROIMAGE. 2010;52(2):686-698

Characterizing the neural correlates of modality-specific and modality-independent accessibility and availability signals in memory using partial-least squares

Salami A; Eriksson J; Kompus K; Habib R; Kauppi K; Nyberg L
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Alla övriga publikationer

Corrigendum: ALZHEIMERS RESEARCH & THERAPY. 2024;16(1):39

Short leukocyte telomeres predict 25-year Alzheimer's disease incidence in non-APOE ε4-carriers (vol 13, 130, 2021)

Hackenhaar FS; Josefsson M; Adolfsson AN; Landfors M; Kauppi K; Hultdin M; Adolfsson R; Degerman S; Pudas S
Review: AGEING RESEARCH REVIEWS. 2020;64:101184

Biological and environmental predictors of heterogeneity in neurocognitive ageing Evidence from Betula and other longitudinal studies

Nyberg L; Boraxbekk C-J; Sorman DE; Hansson P; Herlitz A; Kauppi K; Ljungberg JK; Lovheim H; Lundquist A; Adolfsson AN; Oudin A; Pudas S; Ronnlund M; Stiernstedt M; Sundstrom A; Adolfsson R

Forskningsbidrag

Mapping the heterogeneity of inherited risk factors for Alzheimer’s Disease

Swedish Research Council

1 January 2023 - 31 December 2025
Integrating network medicine with neuropsychiatric genetics to inform drug development and personalized medicine

Swedish Research Council

1 January 2018 - 31 December 2021
Overlapping genetic factors of schizophrenia, cognition and brain structure

Swedish Research Council

1 January 2015 - 31 December 2017

Om mig

Artiklar

Alla övriga publikationer

Forskningsbidrag

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