Jonas Frisén

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Professor i stamcellsforskning.

Artiklar

Article: GENOME BIOLOGY. 2024;25(1):214
Inferring clonal somatic mutations directed by X chromosome inactivation status in single cells
Demirci I; Larsson AJM; Chen X; Hartman J; Sandberg R; Frisen J
Article: CELL SYSTEMS. 2024;15(2):149-165.e10
Clonally heritable gene expression imparts a layer of diversity within cell types
Mold JE; Weissman MH; Ratz M; Hagemann-Jensen M; Hard J; Eriksson C-J; Toosi H; Berghenstrahle J; Ziegenhain C; von Berlin L; Martin M; Blom K; Lagergren J; Lundeberg J; Sandberg R; Michaeeurolsson J; Frisen J
Article: SCIENCE. 2023;382(6675):1137
Spatial transcriptomics of B cell and T cell receptors reveals lymphocyte clonal dynamics
Engblom C; Thrane K; Lin Q; Andersson A; Toosi H; Chen X; Steiner E; Lu C; Mantovani G; Hagemann-Jensen M; Saarenpaa S; Jangard M; Saez-Rodriguez J; Michaelsson J; Hartman J; Lagergren J; Mold JE; Lundeberg J; Frisen J
Article: BIORXIV. 2023;:2023.09.14.557681
A latent cardiomyocyte regeneration potential in human heart disease.
Derks W; Rode J; Collin S; Rost F; Heinke P; Hariharan A; Pickel L; Simonova I; Lázár E; Graham E; Jashari R; Andrä M; Jeppsson A; Salehpour M; Alkass K; Druid H; Kyriakopoulos CP; Taleb I; Shankar TS; Selzman CH; Sadek H; Jovinge S; Brusch L; Frisén J; Drakos S; Bergmann O
Article: NATURE BIOTECHNOLOGY. 2023;41(8):1085-1088
Solid-phase capture and profiling of open chromatin by spatial ATAC
Llorens-Bobadilla E; Zamboni M; Marklund M; Bhalla N; Chen X; Hartman J; Frisen J; Stahl PL
Article: NATURE COMMUNICATIONS. 2023;14(1):2184
DRAG in situ barcoding reveals an increased number of HSPCs contributing to myelopoiesis with age
Urbanus J; Cosgrove J; Beltman JBB; Elhanati Y; Moral RAA; Conrad C; van Heijst JWW; Tubeuf E; Velds A; Kok L; Merle C; Magnusson JPP; Guyonnet L; Frisen J; Fre S; Walczak AMM; Mora T; Jacobs H; Schumacher TNN; Perie L
Article: HIPPOCAMPUS. 2023;33(4):391-401
Early fate bias in neuroepithelial progenitors of hippocampal neurogenesis
von Berlin L; Westholm JO; Ratz M; Frisen J
Article: DEVELOPMENTAL CELL. 2023;58(3):239-255.e10
An ependymal cell census identifies heterogeneous and ongoing cell maturation in the adult mouse spinal cord that changes dynamically on injury
Albors AR; Singer GA; Llorens-Bobadilla E; Frisen J; May AP; Ponting CP; Storey KG
Article: MOLECULAR ONCOLOGY. 2022;16(19):3452-3464
Prostate cancer disease recurrence after radical prostatectomy is associated with HLA type and local cytomegalovirus immunity
Classon J; Zamboni M; Engblom C; Alkass K; Mantovani G; Pou C; Nkulikiyimfura D; Brodin P; Druid H; Mold J; Frisen J
Article: NATURE NEUROSCIENCE. 2022;25(3):285-294
Clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics
Ratz M; von Berlin L; Larsson L; Martin M; Westholm JO; La Manno G; Lundeberg J; Frisen J
Article: CELL REPORTS. 2022;38(9):110440
Identification of a discrete subpopulation of spinal cord ependymal cells with neural stem cell properties
Stenudd M; Sabelstrom H; Llorens-Bobadilla E; Zamboni M; Blom H; Brismar H; Zhang S; Basak O; Clevers H; Goritz C; Barnabe-Heider F; Frisen J
Article: NATURE COMMUNICATIONS. 2021;12(1):6012
Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions
Andersson A; Larsson L; Stenbeck L; Salmen F; Ehinger A; Wu SZ; Al-Eryani G; Roden D; Swarbrick A; Borg A; Frisen J; Engblom C; Lundeberg J
Article: NATURE COMMUNICATIONS. 2021;12(1):5501
Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesions
Dias DO; Kalkitsas J; Kelahmetoglu Y; Estrada CP; Tatarishvili J; Holl D; Jansson L; Banitalebi S; Amiry-Moghaddam M; Ernst A; Huttner HB; Kokaia Z; Lindvall O; Brundin L; Frisen J; Goritz C
Article: CELL REPORTS. 2021;35(8):109174
Divergent clonal differentiation trajectories establish CD8⁺ memory T cell heterogeneity during acute viral infections in humans
Mold JE; Modolo L; Hard J; Zamboni M; Larsson AJM; Stenudd M; Eriksson C-J; Durif G; Stahl PL; Borgstrom E; Picelli S; Reinius B; Sandberg R; Reu P; Talavera-Lopez C; Andersson B; Blom K; Sandberg JK; Picard F; Michaelsson J; Frisen J
Article: NATURE GENETICS. 2021;53(5):694-706
Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin
Kameneva P; Artemov AV; Kastriti ME; Faure L; Olsen TK; Otte J; Erickson A; Semsch B; Andersson ER; Ratz M; Frisen J; Tischler AS; de Krijger RR; Bouderlique T; Akkuratova N; Vorontsova M; Gusev O; Fried K; Sundstrom E; Mei S; Kogner P; Baryawno N; Kharchenko PV; Adameyko I
Article: ONCOGENE. 2021;40(16):2830-2841
The age of adult pilocytic astrocytoma cells
Voronina N; Aichmueller C; Kolb T; Korshunov A; Ryzhova M; Barnholtz-Sloan J; Cioffi G; Sill M; von Deimling A; Pfister SM; Gronych J; Jones DTW; Frisen J; Zapatka M; Ernst A
Article: NATURE COMMUNICATIONS. 2020;11(1):5860
Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury
Floriddia EM; Lourenco T; Zhang S; van Bruggen D; Hilscher MM; Kukanja P; dos Santos JPG; Altinkok M; Yokota C; Llorens-Bobadilla E; Mulinyawe SB; Graos M; Sun LO; Frisen J; Nilsson M; Castelo-Branco G
Article: SCIENCE. 2020;370(6512):eabb8795
A latent lineage potential in resident neural stem cells enables spinal cord repair
Llorens-Bobadilla E; Chell JM; Le Merre P; Wu Y; Zamboni M; Bergenstrahle J; Stenudd M; Sopova E; Lundeberg J; Shupliakov O; Carlen M; Frisen J
Article: CELL STEM CELL. 2020;27(4):605-617.e5
A Widespread Neurogenic Potential of Neocortical Astrocytes Is Induced by Injury
Zamboni M; Llorens-Bobadilla E; Magnusson JP; Frisen J
Article: ELIFE. 2020;9:e59733
Activation of a neural stem cell transcriptional program in parenchymal astrocytes
Magnusson JP; Zamboni M; Santopolo G; Mold JE; Barrientos-Somarribas M; Talavera-Lopez C; Andersson B; Frisen J
Article: CELLS. 2020;9(7):E1732-1732
Blocking Notch-Signaling Increases Neurogenesis in the Striatum after Stroke
Santopolo G; Magnusson JP; Lindvall O; Kokaia Z; Frisen J
Journal article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(159)
Induction of Leptomeningeal Cells Modification Via Intracisternal Injection
Zamboni M; Santopolo G; Frisén J
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(159)
Induction of Leptomeningeal Cells Modification Via Intracisternal Injection
Zamboni M; Santopolo G; Frisen J
Article: PLOS BIOLOGY. 2019;17(10):e3000383
Cell generation dynamics underlying naive T-cell homeostasis in adult humans
Mold JE; Reu P; Olin A; Bernard S; Michaelsson J; Rane S; Yates A; Khosravi A; Salehpour M; Possnert G; Brodin P; Frisen J
Article: NATURE METHODS. 2019;16(10):987-990
High-definition spatial transcriptomics for in situ tissue profiling
Vickovic S; Eraslan G; Salmen F; Klughammer J; Stenbeck L; Schapiro D; Aijo T; Bonneau R; Bergenstrahle L; Navarro JF; Gould J; Griffin GK; Borg A; Ronaghi M; Frisen J; Lundeberg J; Regev A; Stahl PL
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2019;39(7):1432-1447
Disruption of the Extracellular Matrix Progressively Impairs Central Nervous System Vascular Maturation Downstream of β-Catenin Signaling
Jensen LD; Hot B; Ramskold D; Germano RFV; Yokota C; Giatrellis S; Lauschke VM; Hubmacher D; Li MX; Hupe M; Arnold TD; Sandberg R; Frisen J; Trusohamn M; Martowicz A; Wisniewska-Kruk J; Nyqvist D; Adams RH; Apte SS; Vanhollebeke B; Stenman JM; Kele J
Article: GENOME BIOLOGY. 2019;20(1):68
Conbase: a software for unsupervised discovery of clonal somatic mutations in single cells through read phasing
Hard J; Al Hakim E; Kindblom M; Bjorklund AK; Sennblad B; Demirci I; Paterlini M; Reu P; Borgstrom E; Stahl PL; Michaelsson J; Mold JE; Frisen J
Article: NATURE BIOTECHNOLOGY. 2019;37(3):232-237
Regenerating the field of cardiovascular cell therapy
Chien KR; Frisen J; Fritsche-Danielson R; Melton DA; Murry CE; Weissman IL
Article: NATURE. 2019;566(7745):538-542
Dynamics of oligodendrocyte generation in multiple sclerosis
Yeung MSY; Djelloul M; Steiner E; Bernard S; Salehpour M; Possnert G; Brundin L; Frisen J
Article: NATURE PROTOCOLS. 2018;13(11):2501-2534
Barcoded solid-phase RNA capture for Spatial Transcriptomics profiling in mammalian tissue sections
Salmen F; Stahl PL; Mollbrink A; Navarro JF; Vickovic S; Frisen J; Lundeberg J
Article: LANCET NEUROLOGY. 2018;17(10):918-926
The hippocampus in multiple sclerosis
Rocca MA; Barkhof F; De Luca J; Frisen J; Geurts JJG; Hulst HE; Sastre-Garriga J; Filippi M
Article: CELL. 2018;173(1):153-165.e22
Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury
Dias DO; Kim H; Holl D; Solnestam BW; Lundeberg J; Carlen M; Goritz C; Frisen J
Article: EBIOMEDICINE. 2018;27:176-181
Meningioma growth dynamics assessed by radiocarbon retrospective birth dating
Huttner HB; Bergmann O; Salehpour M; El Cheikh R; Nakamura M; Tortora A; Heinke P; Coras R; Englund E; Eyuepoglu IY; Kuramatsu JB; Roeder SS; Kloska SP; Muehlen I; Doerfler A; Schwab S; Possnert G; Bernard S; Frisen J
Article: CIRCULATION. 2017;136(7):680-686
Cardiomyocyte Regeneration A Consensus Statement
Eschenhagen T; Bolli R; Braun T; Field LJ; Fleischmann BK; Frisen J; Giacca M; Hare JM; Houser S; Lee RT; Marbn E; Martin JF; Molkentin JD; Murry CE; Riley PR; Ruiz-Lozano P; Sadek HA; Sussman MA; Hill JA
Article: CELL REPORTS. 2017;20(4):779-784
The Lifespan and Turnover of Microglia in the Human Brain
Reu P; Khosravi A; Bernard S; Mold JE; Salehpour M; Alkass K; Perl S; Tisdale J; Possnert G; Druid H; Frisen J
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2017;214(2):309-317
Antibody-secreting plasma cells persist for decades in human intestine
Landsverk OJB; Snir O; Casado RB; Richter L; Mold JE; Reu P; Horneland R; Paulsen V; Yaqub S; Aandahl EM; Oyen OM; Thorarensen HS; Salehpour M; Possnert G; Frisen J; Sollid LM; Baekkevold ES; Jahnsen FL
Article: PLOS ONE. 2017;12(2):e0171566
Comparison of whole genome amplification techniques for human single cell exome sequencing
Borgstrom E; Paterlini M; Mold JE; Frisen J; Lundeberg J
Article: NATURE GENETICS. 2016;48(11):1430-1435
Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq
Reinius B; Mold JE; Ramskold D; Deng Q; Johnsson P; Michaelsson J; Frisen J; Sandberg R
Article: EXPERIMENTAL CELL RESEARCH. 2016;348(1):10-22
Eph receptor interclass cooperation is required for the regulation of cell proliferation
Jurek A; Genander M; Kundu P; Catchpole T; He X; Straat K; Sabelstrom H; Xu N-J; Pettersson S; Henkemeyer M; Frisen J
Article: NATURE COMMUNICATIONS. 2016;7:13182
Massive and parallel expression profiling using microarrayed single-cell sequencing
Vickovic S; Stahl PL; Salmen F; Giatrellis S; Westholm JO; Mollbrink A; Navarro JF; Custodio J; Bienko M; Sutton L-A; Rosenquist R; Frisen J; Lundeberg J
Article: SCIENCE. 2016;353(6294):78-82
Visualization and analysis of gene expression in tissue sections by spatial transcriptomics
Stahl PL; Salmen F; Vickovic S; Lundmark A; Navarro JF; Magnusson J; Giacomello S; Asp M; Westholm JO; Huss M; Mollbrink A; Linnarsson S; Codeluppi S; Borg A; Ponten F; Costea PI; Sahlen P; Mulder J; Bergmann O; Lundeberg J; Frisen J
Article: CELL METABOLISM. 2015;22(3):408-417
Transplanted Bone Marrow-Derived Cells Contribute to Human Adipogenesis
Ryden M; Uzunel M; Hard JL; Borgstrom E; Mold JE; Arner E; Mejhert N; Andersson DP; Widlund Y; Hassan M; Jones CV; Spalding KL; Svahn B-M; Ahmadian A; Frisen J; Bernard S; Mattsson J; Arner P
Article: STEM CELL REPORTS. 2015;5(2):174-184
Alpha-Synuclein Expression in the Oligodendrocyte Lineage: an In Vitro and In Vivo Study Using Rodent and Human Models
Djelloul M; Holmqvist S; Boza-Serrano A; Azevedo C; Yeung MS; Goldwurm S; Frisen J; Deierborg T; Roybon L
Article: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. 2015;7(7):a018994
Adult Neurogenesis in Humans
Bergmann O; Spalding KL; Frisen J
Article: CELL. 2015;161(7):1566-1575
Dynamics of Cell Generation and Turnover in the Human Heart
Bergmann O; Zdunek S; Felker A; Salehpour M; Alkass K; Bernard S; Sjostrom SL; Szewczykowska M; Jackowska T; dos Remedios C; Malm T; Andrae M; Jashari R; Nyengaard JR; Possnert G; Jovinge S; Druid H; Frisen J
Article: SCIENCE TRANSLATIONAL MEDICINE. 2015;7(281):281ra44
An EphB-Abl signaling pathway is associated with intestinal tumor initiation and growth
Kundu P; Genander M; Straat K; Classon J; Ridgway RA; Tan EH; Bjork J; Martling A; van Es J; Sansom OJ; Clevers H; Pettersson S; Frisen J
Article: JOURNAL OF CLINICAL INVESTIGATION. 2015;125(3):1339-1346
Safety and tolerability of intracerebroventricular PDGF-BB in Parkinson's disease patients
Paul G; Zachrisson O; Varrone A; Almqvist P; Jerling M; Lind G; Rehncrona S; Linderoth B; Bjartmarz H; Shafer LL; Coffey R; Svensson M; Mercer KJ; Forsberg A; Halldin C; Svenningsson P; Widner H; Frisen J; Palhagen S; Haegerstrand A
Article: JAMA NEUROLOGY. 2015;72(2):235-237
Role of Endogenous Neural Stem Cells in Spinal Cord Injury and Repair
Stenudd M; Sabelstroem H; Frisen J
Article: PLOS BIOLOGY. 2015;13(1):e1002045
Adult Neurogenesis in Humans-Common and Unique Traits in Mammals
Ernst A; Frisen J
Article: CELL. 2014;159(4):766-774
Dynamics of Oligodendrocyte Generation and Myelination in the Human Brain
Yeung MSY; Zdunek S; Bergmann O; Bernard S; Salehpour M; Alkass K; Perl S; Tisdale J; Possnert G; Brundin L; Druid H; Frisen J
Article: SCIENCE. 2014;346(6206):237-241
A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse
Magnusson JP; Goritz C; Tatarishvili J; Dias DO; Smith EMK; Lindvall O; Kokaia Z; Frisen J
Article: NEURON. 2014;83(5):1085-1097
A Transcriptional Mechanism Integrating Inputs from Extracellular Signals to Activate Hippocampal Stem Cells
Andersen J; Urban N; Achimastou A; Ito A; Simic M; Ullom K; Martynoga B; Lebel M; Goritz C; Frisen J; Nakafuku M; Guillemot F
Article: NATURE NEUROSCIENCE. 2014;17(6):801-803
The age and genomic integrity of neurons after cortical stroke in humans
Huttner HB; Bergmann O; Salehpour M; Racz A; Tatarishvili J; Lindgren E; Csonka T; Csiba L; Hortobagyi T; Mehes G; Englund E; Solnestam BW; Zdunek S; Scharenberg C; Strom L; Stahl P; Sigurgeirsson B; Dahl A; Schwab S; Possnert G; Bernard S; Kokaia Z; Lindvall O; Lundeberg J; Frisen J
Article: CELL. 2014;156(5):1072-1083
Neurogenesis in the Striatum of the Adult Human Brain
Ernst A; Alkass K; Bernard S; Salehpour M; Perl S; Tisdale J; Possnert G; Druid H; Frisen J
Article: SCIENCE. 2013;342(6158):637-640
Resident Neural Stem Cells Restrict Tissue Damage and Neuronal Loss After Spinal Cord Injury in Mice
Sabelstrom H; Stenudd M; Reu P; Dias DO; Elfineh M; Zdunek S; Damberg P; Goritz C; Frisen J
Article: CELL. 2013;153(6):1219-1227
Dynamics of Hippocampal Neurogenesis in Adult Humans
Spalding KL; Bergmann O; Alkass K; Bernard S; Salehpour M; Huttner HB; Bostrom E; Westerlund I; Vial C; Buchholz BA; Possnert G; Mash DC; Druid H; Frisen J
Article: LAKARTIDNINGEN. 2012;109(41):1814
[2012 Nobel Prize in Physiology or Medicine. Nobel Prize for a life return ticket].
Frisén J
Article: NEURON. 2012;74(4):634-639
The Age of Olfactory Bulb Neurons in Humans
Bergmann O; Liebl J; Bernard S; Alkass K; Yeung MSY; Steier P; Kutschera W; Johnson L; Landen M; Druid H; Spalding KL; Frisen J
Article: SCIENCE. 2011;333(6039):238-242
A Pericyte Origin of Spinal Cord Scar Tissue
Goritz C; Dias DO; Tomilin N; Barbacid M; Shupliakov O; Frisen J
Article: CELL STEM CELL. 2011;8(4):426-433
Dopamine Controls Neurogenesis in the Adult Salamander Midbrain in Homeostasis and during Regeneration of Dopamine Neurons
Berg DA; Kirkham M; Wang H; Frisen J; Simon A
Article: EXPERIMENTAL CELL RESEARCH. 2011;317(2):188-194
Identification of cardiomyocyte nuclei and assessment of ploidy for the analysis of cell turnover
Bergmann O; Zdunek S; Alkass K; Druid H; Bernard S; Frisen J
Article: CELL STEM CELL. 2010;7(6):730-743
EphB Signaling Controls Lineage Plasticity of Adult Neural Stem Cell Niche Cells
Nomura T; Goritz C; Catchpole T; Henkemeyer M; Frisen J
Article: JOURNAL OF NEUROSCIENCE. 2010;30(41):13794-13807
RBPJκ-Dependent Signaling Is Essential for Long-Term Maintenance of Neural Stem Cells in the Adult Hippocampus
Ehm O; Goritz C; Covic M; Schaeffner I; Schwarz TJ; Karaca E; Kempkes B; Kremmer E; Pfrieger FW; Espinosa L; Bigas A; Giachino C; Taylor V; Frisen J; Lie DC
Article: CELL STEM CELL. 2010;7(4):470-482
Origin of New Glial Cells in Intact and Injured Adult Spinal Cord
Barnabe-Heider F; Goritz C; Sabelstrom H; Takebayashi H; Pfrieger FW; Meletis K; Frisen J
Article: CURRENT OPINION IN CELL BIOLOGY. 2010;22(5):611-616
Ephrins and Eph receptors in stem cells and cancer
Genander M; Frisen J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(33):14657-14661
Efficient reprogramming of adult neural stem cells to monocytes by ectopic expression of a single gene
Forsberg M; Carlen M; Meletis K; Yeung MSY; Barnabe-Heider F; Persson MAA; Aarum J; Frisen J
Article: STEM CELLS. 2010;28(7):1196-1205
Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle
Genander M; Holmberg J; Frisen J
Article: STEM CELLS. 2010;28(5):974-983
Impaired Hippocampal Neurogenesis and Vascular Formation in Ephrin-A5-Deficient Mice
Hara Y; Nomura T; Yoshizaki K; Frisen J; Osumi N
Article: BRAIN. 2010;133(Pt 4):983-995
A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2α
Seidel S; Garvalov BK; Wirta V; von Stechow L; Schaenzer A; Meletis K; Wolter M; Sommerlad D; Henze A-T; Nister M; Reifenberger G; Lundeberg J; Frisen J; Acker T
Article: DIABETES. 2010;59(1):105-109
Adipocyte Turnover: Relevance to Human Adipose Tissue Morphology
Arner E; Westermark PO; Spalding KL; Britton T; Ryden M; Frisen J; Bernard S; Arner P
Article: CELL. 2009;139(4):679-692
Dissociation of EphB2 Signaling Pathways Mediating Progenitor Cell Proliferation and Tumor Suppression
Genander M; Halford MM; Xu N-J; Eriksson M; Yu Z; Qiu Z; Martling A; Greicius G; Thakar S; Catchpole T; Chumley MJ; Zdunek S; Wang C; Holm T; Goff SP; Pettersson S; Pestell RG; Henkemeyer M; Frisen J
Article: PLOS ONE. 2009;4(9):e6997
High-density microwell chip for culture and analysis of stem cells.
Lindström S; Eriksson M; Vazin T; Sandberg J; Lundeberg J; Frisén J; Andersson-Svahn H
Article: SCIENCE. 2009;324(5923):98-102
Evidence for Cardiomyocyte Renewal in Humans
Bergmann O; Bhardwaj RD; Bernard S; Zdunek S; Barnabe-Heider F; Walsh S; Zupicich J; Alkass K; Buchholz BA; Druid H; Jovinge S; Frisen J
Article: NATURE NEUROSCIENCE. 2009;12(3):259-267
Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke
Carlen M; Meletis K; Goritz C; Darsalia V; Evergren E; Tanigaki K; Amendola M; Barnabe-Heider F; Yeung MSY; Naldini L; Honjo T; Kokaia Z; Shupliakov O; Cassidy RM; Lindvall O; Frisen J
Article: EXPERIMENTAL CELL RESEARCH. 2008;314(17):3255-3263
Induced pluripotency with endogenous and inducible genes
Duinsbegen D; Eriksson M; 't Hoen PAC; Frisen J; Mikkers H
Article: PLOS ONE. 2008;3(10):e3322
Meltrin beta/ADAM19 interacting with EphA4 in developing neural cells participates in formation of the neuromuscular junction.
Yumoto N; Wakatsuki S; Kurisaki T; Hara Y; Osumi N; Frisén J; Sehara-Fujisawa A
Article: DEVELOPMENT. 2008;135(19):3281-3290
Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of the mammalian striatum
Passante L; Gaspard N; Degraeve M; Frisen J; Kullander K; De Maertelaer V; Vanderhaeghen P
Article: PLOS BIOLOGY. 2008;6(7):e182-1507
Spinal cord injury reveals multilineage differentiation of ependymal cells
Meletis K; Barnabe-Heider F; Carlen M; Evergren E; Tomilin N; Shupliakov O; Frisen J
Article: CELL STEM CELL. 2008;3(1):16-24
Stem cells for spinal cord repair
Barnabe-Heider F; Frisen J
Article: NATURE. 2008;453(7196):783-787
Dynamics of fat cell turnover in humans
Spalding KL; Arner E; Westermark PO; Bernard S; Buchholz BA; Bergmann O; Blomqvist L; Hoffstedt J; Naslund E; Britton T; Concha H; Hassan M; Ryden M; Frisen J; Arner P
Article: NATURE METHODS. 2008;5(2):189-196
Genetic manipulation of adult mouse neurogenic niches by in vivo electroporation
Barnabe-Heider F; Meletis K; Eriksson M; Bergmann O; Sabelstrom H; Harvey MA; Mikkers H; Frisen J
Article: GLIA. 2007;55(15):1565-1576
Transgenic mice for conditional gene manipulation in astroglial cells
Slezak M; Goritz C; Niemiec A; Frisen J; Chambon P; Metzger D; Pfrieger FW
Article: STEM CELLS. 2007;25(6):1539-1545
High-throughput identification of genes promoting neuron formation and lineage choice in mouse embryonic stem cells
Falk A; Karlsson TE; Kurdija S; Frisen J; Zupicich J
Article: SCIENCE. 2007;315(5816):1243-1249
Human neuroblasts migrate to the olfactory bulb via a lateral ventricular extension
Curtis MA; Kam M; Nannmark U; Anderson MF; Axell MZ; Wikkelso C; Holtas S; van Roon-Mom WMC; Bjork-Eriksson T; Nordborg C; Frisen J; Dragunow M; Faull RLM; Eriksson PS
Article: EXPERIMENTAL CELL RESEARCH. 2006;312(15):2851-2859
Genetic visualization of neurogenesis
Carlen M; Meletis K; Barnabe-Heider F; Frisen J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(33):12564-12568
Neocortical neurogenesis in humans is restricted to development
Bhardwaj RD; Curtis MA; Spalding KL; Buchholz BA; Fink D; Bjork-Eriksson T; Nordborg C; Gage FH; Druid H; Eriksson PS; Frisen J
Article: NEUROSCIENCE. 2006;141(1):109-121
Ephrin-A5 modulates the topographic mapping and connectivity of commissural axons in murine hippocampus
Otal R; Burgaya F; Frisen J; Soriano E; Martinez A
Article: CELL. 2006;125(6):1151-1163
EphB receptors coordinate migrationand proliferation in the intestinal stem cell niche
Holmberg J; Genander M; Halford MM; Anneren C; Sondell M; Chumley MJ; Silvany RE; Henkemeyer M; Frisen J
Article: EXPERIMENTAL CELL RESEARCH. 2006;312(10):1798-1812
Catalog of gene expression in adult neural stem cells and their in vivo microenvironment
Williams C; Wirta V; Meletis K; Wikstrom L; Carlsson L; Frisen J; Lundeberg J
Article: NANOTECHNOLOGY. 2006;17(8):1911-1915
Magnetic resonance tracking of nanoparticle labelled neural stem cells in a rat's spinal cord
Wang FH; Lee IH; Holmstrom N; Yoshitake T; Kim DK; Muhammed M; Frisen J; Olson L; Spenger C; Kehr J
Article: DEVELOPMENT. 2006;133(7):1335-1345
Pax6-dependent boundary defines alignment of migrating olfactory cortex neurons via the repulsive activity of ephrin A5
Nomura T; Holmberg J; Frisen J; Osumi N
Article: DEVELOPMENT. 2006;133(2):363-369
P53 suppresses the self-renewal of adult neural stem cells
Meletis K; Wirta V; Hede SM; Nistér M; Lundeberg J; Frisén J
Article: BMC NEUROSCIENCE. 2005;6:55
Epidermal growth factor (EGF) withdrawal masks gene expression differences in the study of pituitary adenylate cyclase-activating polypeptide (PACAP) activation of primary neural stem cell proliferation -: art. no. 55
Sievertzon M; Wirta V; Mercer A; Frisén J; Lundeberg J
Article: EMBO JOURNAL. 2005;24(15):2715-2719
Deconstructing stemness
Mikkers H; Frisén J
Article: CELL. 2005;122(1):133-143
Retrospective birth dating of cells in humans
Spalding KL; Bhardwaj RD; Buchholz BA; Druid H; Frisén J
Article: BMC NEUROSCIENCE. 2005;6:28
Transcriptome analysis in primary neural stem cells using a tag cDNA amplification method -: art. no. 28
Sievertzon M; Wirta V; Mercer A; Meletis K; Erlandsson R; Wikström L; Frisén J; Lundeberg J
Article: NATURE NEUROSCIENCE. 2005;8(3):346-353
Allodynia limits the usefulness of intraspinal neural stem cell grafts; directed differentiation improves outcome
Hofstetter CP; Holmström NAV; Lilja JA; Schweinhardt P; Hao JX; Spenger C; Wiesenfeld-Hallin Z; Kurpad SN; Frisén J; Olson L
Article: GENES & DEVELOPMENT. 2005;19(4):462-471
Ephrin-A2 reverse signaling negatively regulates neural progenitor proliferation and neurogenesis
Holmberg J; Armulik A; Senti KA; Edoff K; Spalding K; Momma S; Cassidy R; Flanagan JG; Frisén J
Article: EXPERIMENTAL CELL RESEARCH. 2005;302(1):40-47
Survival and neural differentiation of adult neural stem cells transplanted into the mature inner ear
Hu ZQ; Wei DG; Johansson CB; Holmström N; Duan ML; Frisén J; Ulfendahl M
Article: CELL. 2003;114(3):311-322
Axonal ephrin-as and odorant receptors:: Coordinate determination of the olfactory sensory map
Cutforth T; Moring L; Mendelsohn M; Nemes A; Shah NM; Kim MM; Frisén J; Axel R
Article: NEURON. 2003;39(3):453-465
Area specificity and topography of thalamocortical projections are controlled by ephrin/Eph genes
Dufour A; Seibt J; Passante L; Depaepe V; Ciossek T; Frisén J; Kullander K; Flanagan JG; Polleux F; Vanderhaeghen P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2003;100(13):7925-7930
Evidence for neurogenesis in the adult mammalian substantia nigra
Zhao M; Momma S; Delfani K; Carlén M; Cassidy RM; Johansson CB; Brismar H; Shupliakov O; Frisén J; Janson AM
Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2002;69(6):757-762
Amphiregulin is a mitogen for adult neural stem cells
Falk A; Frisén J
Article: EXPERIMENTAL CELL RESEARCH. 2002;279(1):34-39
Gene delivery to adult neural stem cells
Falk A; Holmström N; Carlén M; Cassidy R; Lundberg C; Frisén J
Article: CURRENT BIOLOGY. 2002;12(7):606-608
Functional integration of adult-born neurons
Carlén M; Cassidy RM; Brismar H; Smith GA; Enquist LW; Frisén J
Article: BIOESSAYS. 2001;23(1):3-7
Oh no, Notch again!
Frisén J; Lendahl U
Article: NATURE. 2000;408(6809):203-206
Regulation of repulsion versus adhesion by different splice forms of an Eph receptor
Holmberg J; Clarke DL; Frisén J
Article: JOURNAL OF NEUROSCIENCE. 2000;20(15):5841-5847
Malformation of the functional organization of somatosensory cortex in adult ephrin-A5 knock-out mice revealed by in vivo functional imaging
Prakash N; Vanderhaeghen P; Cohen-Cory S; Frisén J; Flanagan JG; Frostig RD
Article: SCIENCE. 2000;288(5471):1660-1663
Generalized potential of adult neural stem cells
Clarke DL; Johansson CB; Wilbertz J; Veress B; Nilsson E; Karlström H; Lendahl U; Frisén J
Article: NATURE NEUROSCIENCE. 2000;3(4):358-365
A mapping label required for normal scale of body representation in the cortex
Vanderhaeghen P; Lu Q; Prakash N; Frisén J; Walsh CA; Frostig RD; Flanagan JG
Article: NEURON. 2000;25(3):563-574
Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping.
Feldheim DA; Kim YI; Bergemann AD; Frisén J; Barbacid M; Flanagan JG
Article: EXPERIMENTAL CELL RESEARCH. 2000;255(1):47-55
Expression of the adenovirus receptor and its interaction with the fiber knob
Tomko RP; Johansson CB; Totrov M; Abagyan R; Frisén J; Philipson L
Article: NEURON. 2000;25(2):295-306
Roles for ephrins in positionally selective synaptogenesis between motor neurons and muscle fibers
Feng GP; Laskowski MB; Feldheim DA; Wang HM; Lewis R; Frisen J; Flanagan JG; Sanes JR
Article: EXPERIMENTAL CELL RESEARCH. 1999;253(2):733-736
Neural stem cells in the adult human brain
Johansson CB; Svensson M; Wallstedt L; Janson AM; Frisén J
Article: JOURNAL OF CELL BIOLOGY. 1999;145(3):503-514
Abnormal reaction to central nervous system injury in mice lacking glial fibrillary acidic protein and vimentin
Pekny M; Johansson CB; Eliasson C; Stakeberg J; Wallén Å; Perlmann T; Lendahl U; Betsholtz C; Berthold CH; Frisén J
Article: CELL. 1999;96(1):25-34
Identification of a neural stem cell in the adult mammalian central nervous system
Johansson CB; Momma S; Clarke DL; Risling M; Lendahl U; Frisén J
Article: NEURON. 1998;21(6):1303-1313
Topographic guidance labels in a sensory projection to the forebrain
Feldheim DA; Vanderhaeghen P; Hansen MJ; Frisén J; Lu Q; Barbacid M; Flanagan JG
Article: NATURE. 1998;395(6700):398-402
Retinoid-X receptor signalling in the developing spinal cord
Solomin L; Johansson CB; Zetterström RH; Bissonnette RP; Heyman RA; Olson L; Lendahl U; Frisén J; Perlmann T
Article: JOURNAL OF NEUROSCIENCE. 1998;18(15):5714-5722
Nerve growth factor induces process formation in meningeal cells:: Implications for scar formation in the injured CNS
Frisén J; Risling M; Korhonen L; Zirrgiebel U; Johansson CB; Cullheim S; Lindholm D
Article: NEURON. 1998;20(2):235-243
Ephrin-A5 (AL-1/RAGS) is essential for proper retinal axon guidance and topographic mapping in the mammalian visual system.
Frisén J; Yates PA; McLaughlin T; Friedman GC; O'Leary DD; Barbacid M
Article: CELL AND TISSUE RESEARCH. 1997;290(2):209-215
Genetic analysis of the role of Eph receptors in the development of the mammalian nervous system.
Frisén J; Barbacid M
Article: EMBO JOURNAL. 1997;16(11):3106-3114
Aberrant axonal projections in mice lacking EphA8 (Eek) tyrosine protein kinase receptors.
Park S; Frisén J; Barbacid M
Article: JOURNAL OF NEUROSCIENCE. 1997;17(10):3623-3633
TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death.
Alcántara S; Frisén J; del Río JA; Soriano E; Barbacid M; Silos-Santiago I
Article: GENES & DEVELOPMENT. 1997;11(8):973-983
Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development.
Yan Y; Frisén J; Lee MH; Massagué J; Barbacid M
Article: EXPERIMENTAL NEUROLOGY. 1997;143(1):132-140
Apoptotic death of olfactory sensory neurons in the adult rat
Deckner ML; Risling M; Frisen J
Article: NATURE. 1996;382(6586):70-73
Renal agenesis and the absence of enteric neurons in mice lacking GDNF.
Sánchez MP; Silos-Santiago I; Frisén J; He B; Lira SA; Barbacid M
Article: JOURNAL OF CELL BIOLOGY. 1995;131(2):453-464
RAPID, WIDESPREAD, AND LONG-LASTING INDUCTION OF NESTIN CONTRIBUTES TO THE GENERATION OF GLIAL SCAR TISSUE AFTER CNS INJURY
FRISEN J; JOHANSSON CB; TOROK C; RISLING M; LENDAHL U
Article: NEUROSCIENCE. 1995;65(1):293-304
SPINAL AXONS IN CENTRAL-NERVOUS-SYSTEM SCAR TISSUE ARE CLOSELY-RELATED TO LAMININ-IMMUNOREACTIVE ASTROCYTES
FRISEN J; HAEGERSTRAND A; RISLING M; FRIED K; JOHANSSON CB; HAMMARBERG H; ELDE R; HOKFELT T; CULLHEIM S
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Editorial comment: EUROPEAN UROLOGY ONCOLOGY. 2024;7(5):1144-1146
The Role of Cytomegalovirus in Prostate Cancer Incidence and Mortality
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Revisiting remyelination: Towards a consensus on the regeneration of CNS myelin
Franklina RJM; Frisen J; Lyons DA
Editorial comment: NATURE METHODS. 2021;18(1):15-18
Spatially resolved transcriptomics adds a new dimension to genomics
Larsson L; Frisen J; Lundeberg J
Letter: MOLECULAR PSYCHIATRY. 2020;25(10):2207-2209
Limits to human neurogenesis-really?
Lucassen PJ; Toni N; Kempermann G; Frisen J; Gage FH; Swaab DF
Letter: LANCET. 2020;396(10248):e15
COVID-19-a very visible pandemic
King C; Einhorn L; Brusselaers N; Carlsson M; Einhorn S; Elgh F; Frisen J; Gustafsson A; Hanson S; Hanson C; Hedner T; Isaksson O; Jansson A; Lundkvist A; Lotvall J; Lundback B; Olsen B; Soederberg-Naucler C; Wahlin A; Steineck G; Vahlne A
Editorial comment: NATURE MEDICINE. 2019;25(4):542-543
A fresh look at adult neurogenesis
Steiner E; Tata M; Frisen J
Editorial comment: CELL STEM CELL. 2019;24(3):357-359
Voices: The Importance of Fetal Tissue Research
Weissman I; Rawlins E; Jensen K; Barker R; Beltrao-Braga P; Dekel B; Frisen J; Surani A; Fehlings M
Corrigendum: NATURE. 2019;566(7744):E9
Dynamics of oligodendrocyte generation in multiple sclerosis (vol 566, pg 1, 2019)
Yeung MSY; Djelloul M; Steiner E; Bernard S; Salehpour M; Possnert G; Brundin L; Frisen J
Review: CELL STEM CELL. 2018;23(1):25-30
Human Adult Neurogenesis: Evidence and Remaining Questions
Kempermann G; Gage FH; Aigner L; Song H; Curtis MA; Thuret S; Kuhn HG; Jessberger S; Frankland PW; Cameron HA; Gould E; Hen R; Abrous DN; Toni N; Schinder AF; Zhao X; Lucassen PJ; Frisen J
Review: ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY. 2016;32:127-141
Neurogenesis and Gliogenesis in Nervous System Plasticity and Repair
Frisen J
Review: DEVELOPMENT. 2016;143(7):1075-1086
Stars from the darkest night: unlocking the neurogenic potential of astrocytes in different brain regions
Magnusson JP; Frisen J
Review: EXPERIMENTAL NEUROLOGY. 2014;260:44-49
Neural stem cells in the adult spinal cord
Sabelstrom H; Stenudd M; Frisen J
Editorial comment: SCIENCE. 2013;340(6133):695-696
Why Adults Need New Brain Cells
Bergmann O; Frisen J
Editorial comment: NEW ENGLAND JOURNAL OF MEDICINE. 2013;368(14):1358-1360
New Cells in Old Hearts
Bostrom P; Frisen J
Editorial comment: CELL STEM CELL. 2012;11(3):282-284
Noisy Neurons Keep Neural Stem Cells Quiet
Chell JM; Frisen J
Editorial comment: CELL STEM CELL. 2012;10(6):657-659
Neural Stem Cells and Neurogenesis in the Adult
Goritz C; Frisen J
Letter: CIRCULATION RESEARCH. 2012;110(1):e17-e18
Cardiomyocyte Renewal in Humans
Bergmann O; Zdunek S; Frisen J; Bernard S; Druid H; Jovinge S
Editorial comment: CELL CYCLE. 2010;9(10):1865-1866
Eph receptors tangled up in two Independent control of cell positioning and proliferation
Genander M; Frisen J
Published conference paper: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS. 2010;268(7-8):1295-1298
A mathematical model for the interpretation of nuclear bomb test derived ¹⁴C incorporation in biological systems
Bernard S; Frisen J; Spalding KL
Meeting abstract: NEUROSCIENCE RESEARCH. 2009;65:S101
EphB/ephrin-B signaling controls differentiation plasticity of the adult subventricular niche cells
Nomura T; Frisen J
Editorial comment: CELL. 2007;128(5):825-826
From stem cell to progenitor and back again
Simon A; Frisen J
Meeting abstract: NEUROSCIENCE RESEARCH. 2007;58:S209
The function of Ephrin-Eph signaling in postnatal neurogenesis
Hara Y; Frisen J; Osumi N
Editorial comment: NATURE. 2005;437(7057):333-334
Age written in teeth by nuclear tests
Spalding KL; Buchholz BA; Bergman LE; Druid H; Frisén J
Review: ANNALS OF MEDICINE. 2005;37(7):480-486
New neurons in old brains
Falk A; Frisén J
Published conference paper: JOURNAL OF NEUROSCIENCE RESEARCH. 2004;76(2):205-215
PACAP promotes neural stem cell proliferation in adult mouse brain
Mercer A; Rönnholm H; Holmberg J; Lundh H; Heidrich J; Zachrisson O; Ossoinak A; Frisén J; Patrone C
Meeting abstract: SHOCK. 2004;21:136
Grafting of genetically modified adult neural stem cells following an incomplete spinal cord injury
Holmström NAV; Hofstetter CP; Schweinhardt P; Spenger C; Frisén J; Olson L; Kurpad S
Editorial comment: TRENDS IN NEUROSCIENCES. 2003;26(6):292-296
Blood on the tracks:: a simple twist of fate?
Meletis K; Frisén J
Letter: CELL DEATH AND DIFFERENTIATION. 2002;9(12):1377-1378
Cell death in adult neural stem cells
Sleeper E; Tamm C; Frisén J; Zhivotovsky B; Orrenius S; Ceccatelli S
Editorial comment: CURRENT BIOLOGY. 2002;12(20):R705-R706
Embryonic stem cells:: Taming the fountain of youth
Cassidy R; Frisén J
Review: NEURON. 2002;35(3):415-418
Stem cell plasticity?
Frisén J
Review: TRENDS IN NEUROSCIENCES. 2002;25(5):239-243
Ephrins are not only unattractive
Holmberg J; Frisén J
Editorial comment: JOURNAL OF CELL BIOLOGY. 2001;155(5):699-702
Have the bloody cells gone to our heads?
Meletis K; Frisén J
Review: CURRENT OPINION IN GENETICS & DEVELOPMENT. 2001;11(5):575-580
Differentiation potential of adult stem cells
Clarke D; Frisén J
Editorial comment: NEURON. 2001;31(6):876-877
Eph receptors tingle the spine
Henkemeyer M; Frisén J
Editorial comment: NATURE. 2001;412(6848):690-691
Neurobiology -: Stem cells on the brain
Cassidy R; Frisén J
Published conference paper: ACTA NEUROLOGICA SCANDINAVICA. 2000;102:34
Characterization of neural stem cells in the adult CNS
Johansson CB; Momma S; Clarke DL; Lendahl U; Frisen J
Review: LAKARTIDNINGEN. 2000;97(24):2962-2966
[The up and down world: glia makes nerve cells!].
Frisén J
Review: CURRENT OPINION IN NEUROBIOLOGY. 2000;10(1):45-49
Get to know your stem cells
Momma S; Johansson CB; Frisén J
Conference publication: EUROPEAN JOURNAL OF NEUROSCIENCE. 2000;12:318
Characterization of neural stem cells in the adult CNS
Johansson CB; Momma S; Clarke DL; Lendahl U; Frisen J
Review: EMBO JOURNAL. 1999;18(19):5159-5165
Ephrins and their Eph receptors:: multitalented directors of embryonic development
Frisén J; Holmberg J; Barbacid M
Review: CELLULAR AND MOLECULAR LIFE SCIENCES. 1998;54(9):935-945
Central nervous system stem cells in the embryo and adult
Frisén J; Johansson CB; Lothian C; Lendahl U
Review: HISTOLOGY AND HISTOPATHOLOGY. 1997;12(3):857-868
Determinants of axonal regeneration
Frisen J
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