John Pernow
Professor/Överläkare | Docent
E-postadress: john.pernow@ki.se
Telefon: +46852482807
Besöksadress: Norrbacka S1:02, Karolinska Universitetssjukhuset Solna, 17176 Stockholm
Postadress: K2 Medicin, Solna, K2 Kardio Pernow J, 171 77 Stockholm
Om mig
- Professor i kardiologi vid institutionen för medicin, Solna.
Jag föddes 1960 i Solna. Jag läste medicin vid Karolinska Institutet, blev antagen som doktorand 1985 och disputerade 1988 på en avhandling om betydelsen av neuropeptid Y för blodflödesreglering. Jag legitimerades som läkare 1991. Samma år blev jag docent i farmakologi vid Karolinska Institutet. 1997 fick jag specialistkompetens i både kardiologi och internmedicin. 1998 blev jag docent i kardiologi. Sedan 1991 har jag haft olika befattningar på Karolinska Universitetssjukhuset i Solna, de senaste sex åren kombinerad med en klinisk forskartjänst (50 procent) från Vetenskapsrådet.
Jag har haft en rad förtroendeuppdrag, är bland annat ledamot av Hjärt-Lungfondens Forskningsråd och ingår i FoUU-ledningsgruppen vid Karolinska Universitetssjukhuset. Sedan 2006 är jag chef för enheten för kardiologi, institutionen för medicin, Solna.
Jag utnämndes den 1 juni 2008 till professor i kardiologi vid Karolinska Institutet.
Forskningsbeskrivning
- Hjärtinfarkt är den vanligaste dödsorsaken i Sverige och övriga västvärlden. Faktorer kopplade till arv och livsstil ligger bakom de aterosklerotiska plack som då bildas i kranskärlens väggar. Om placket brister uppstår en blodpropp, blodflödet stryps och patienten får en hjärtinfarkt. Jag vill med sin forskning bidra till att färre insjuknar i hjärtinfarkt och till bättre hjärtfunktion hos dem som drabbats av en akut infarkt.
Artiklar
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2024;327(6):H1431-H1441
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2024;327(5):H1296-H1302
- Journal article: EUROPEAN HEART JOURNAL. 2024;45(40):4249-4251
- Article: BRITISH JOURNAL OF PHARMACOLOGY. 2024
- Article: CLINICAL SCIENCE. 2024;138(15):975-985
- Article: CARDIOVASCULAR DIABETOLOGY. 2024;23(1):122
- Article: VACCINE. 2023;41(48):7159-7165
- Article: JOURNAL OF DIABETES AND ITS COMPLICATIONS. 2023;37(10):108599
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2023;133(17):e167693
- Article: JACC: BASIC TO TRANSLATIONAL SCIENCE. 2023;8(8):907-918
- Article: EUROPEAN HEART JOURNAL OPEN. 2023;3(3):oead058
- Article: JOURNAL OF INTERNAL MEDICINE. 2023;293(2):228-245
- Article: AMERICAN HEART JOURNAL. 2023;255:82-89
- Article: BMJ OPEN. 2022;12(11):e061870
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2022;323(5):H1004-H1009
- Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2022;365:34-40
- Article: BASIC RESEARCH IN CARDIOLOGY. 2022;117(1):46
- Article: REDOX BIOLOGY. 2022;54:102370
- Article: NITRIC OXIDE - BIOLOGY AND CHEMISTRY. 2022;125:69-77
- Article: JACC: BASIC TO TRANSLATIONAL SCIENCE. 2022;7(3):193-204
- Article: DIABETES. 2022;71(2):285-297
- Article: PHARMACOLOGY. 2022;107(3-4):160-166
- Article: JOURNAL OF CLINICAL MEDICINE. 2021;10(24):5863
- Article: CIRCULATION. 2021;144(18):1476-1484
- Article: JOURNAL OF INTERNAL MEDICINE. 2021;290(5):1061-1070
- Article: CURRENT OPINION IN PHARMACOLOGY. 2021;60:183-192
- Article: MICROORGANISMS. 2021;9(6):1137
- Article: FREE RADICAL BIOLOGY AND MEDICINE. 2021;168:95-109
- Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS. 2021;26(3):253-259
- Article: CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS. 2021;97(3):386-392
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2021;320(1):H90-H94
- Article: ESC HEART FAILURE. 2020;7(6):4438-4442
- Article: EUROPEAN HEART JOURNAL: ACUTE CARDIOVASCULAR CARE. 2020;9(8):984-992
- Article: CIRCULATION RESEARCH. 2020;127(10):1261-1273
- Article: CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS. 2020;19:100629
- Article: CELLS. 2020;9(7):E1712-1712
- Article: RESUSCITATION. 2020;150:113-120
- Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2020;111(4):749-756
- Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS. 2020;25(2):164-173
- Article: CLINICAL HEMORHEOLOGY AND MICROCIRCULATION. 2020;74(1):79-92
- Article: ATHEROSCLEROSIS. 2020;292:215-223
- Article: FRONTIERS IN PHARMACOLOGY. 2020;11:603226
- Article: REJUVENATION RESEARCH. 2019;22(5):385-389
- Article: CIRCULATION. 2019;139(23):2654-2663
- Article: OPEN HEART. 2019;6(2):e001109
- Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2019;274:40-44
- Article: CLINICAL MEDICINE INSIGHTS: CARDIOLOGY. 2019;13:1179546819831980
- Article: FRONTIERS IN PHARMACOLOGY. 2019;10:861
- Article: CIRCULATION. 2018;138(24):2754-2762
- Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2018;19(12):E3942-3942
- Article: JOURNAL OF INTERNAL MEDICINE. 2018;284(4):388-398
- Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2018;72(7):769-780
- Article: JACC: BASIC TO TRANSLATIONAL SCIENCE. 2018;3(4):450-463
- Article: JOURNAL OF CARDIAC FAILURE. 2018;24(7):470-478
- Article: REDOX BIOLOGY. 2018;14:328-337
- Article: ACTA PHYSIOLOGICA. 2017;221(3):174-181
- Article: NEW ENGLAND JOURNAL OF MEDICINE. 2017;377(13):1240-1249
- Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2017;47(9):638-648
- Article: JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE. 2017;19(1):55
- Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2017;18(8):E1609-1609
- Article: AMERICAN HEART JOURNAL. 2017;189:94-102
- Article: DIABETES AND VASCULAR DISEASE RESEARCH. 2017;14(3):236-245
- Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2017;47(1):38-43
- Article: CARDIOVASCULAR RESEARCH (CVR). 2016;112(3):669-676
- Article: AMERICAN HEART JOURNAL. 2016;181:66-73
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2016;101(11):3952-3958
- Article: DIABETES AND VASCULAR DISEASE RESEARCH. 2016;13(5):354-360
- Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2016;46(8):707-713
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2016;311(1):H299-H309
- Article: BASIC RESEARCH IN CARDIOLOGY. 2016;111(3):34
- Article: JOURNAL OF INTERNAL MEDICINE. 2016;279(5):477-484
- Article: BMC MEDICAL IMAGING. 2016;16:19
- Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2016;14(3):606-618
- Article: CURRENT VASCULAR PHARMACOLOGY. 2016;14(2):155-162
- Article: OPEN FORUM INFECTIOUS DISEASES. 2015;2(4):ofv155
- Article: BRITISH JOURNAL OF PHARMACOLOGY. 2015;172(19):4684-4698
- Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015;13(3):465-476
- Article: CIRCULATION. GENOMIC AND PRECISION MEDICINE. 2014;7(6):955-964
- Article: LIFE SCIENCES. 2014;118(2):435-439
- Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2014;44(10):965-971
- Article: BASIC RESEARCH IN CARDIOLOGY. 2014;109(2):401
- Article: PEDIATRIC DIABETES. 2014;15(1):51-56
- Article: PLOS ONE. 2014;9(8):e104731
- Article: PLOS ONE. 2014;9(7):e103260
- Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2013;720(1-3):121-123
- Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2013;169(1):83-88
- Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2013;168(2):1017-1022
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(37):15049-15054
- Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2013;712(1-3):16-21
- Article: ACTA PHYSIOLOGICA. 2013;208(2):172-179
- Article: BMC CARDIOVASCULAR DISORDERS. 2013;13:22
- Article: CLINICAL HEMORHEOLOGY AND MICROCIRCULATION. 2013;54(1):75-85
- Article: CIRCULATION. 2012;126(25):2943-2950
- Article: EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING. 2012;13(12):1008-1015
- Article: CIRCULATION RESEARCH. 2012;111(10):1336-1348
- Article: EXPERIMENTAL PHYSIOLOGY. 2012;97(8):908-917
- Article: JOURNAL OF INTERVENTIONAL CARDIOLOGY. 2012;25(2):103-110
- Article: ATHEROSCLEROSIS. 2012;221(1):226-231
- Article: DIABETOLOGIA. 2012;55(3):600-607
- Article: SCANDINAVIAN CARDIOVASCULAR JOURNAL. 2012;46(1):23-31
- Article: PLOS ONE. 2012;7(7):e42038
- Article: DIABETES. 2011;60(8):2061-2067
- Article: CELLULAR SIGNALLING. 2011;23(5):820-826
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2011;300(4):H1174-H1181
- Article: ACTA PHYSIOLOGICA. 2011;201(2):219-226
- Article: HEART. 2010;96(21):1710-1715
- Article: JOURNAL OF NUCLEAR CARDIOLOGY. 2010;17(5):831-840
- Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2010;143(3):368-372
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2010;95(5):2359-2366
- Article: JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE. 2010;12(1):25
- Article: ACTA PHYSIOLOGICA. 2010;198(4):441-448
- Article: CARDIOVASCULAR RESEARCH (CVR). 2010;85(1):147-154
- Article: JOURNAL OF INTERNAL MEDICINE. 2009;266(5):492-498
- Article: JOURNAL OF HYPERTENSION. 2009;27(11):2257-2264
- Article: REGULATORY PEPTIDES. 2009;157(1-3):8-13
- Article: PEDIATRIC DIABETES. 2009;10(5):329-335
- Article: ATHEROSCLEROSIS. 2009;204(1):73-78
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2009;296(3):H719-H727
- Article: THROMBOSIS AND HAEMOSTASIS. 2009;101(1):157-164
- Article: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY. 2008;86(11):745-751
- Article: EUROPEAN HEART JOURNAL. 2008;29(14):1753-1760
- Article: CARDIOVASCULAR RESEARCH (CVR). 2008;78(1):116-122
- Article: JOURNAL OF VASCULAR RESEARCH. 2008;45(4):295-302
- Article: CIRCULATION. 2008;117(18):F103-F105
- Article: BURNS. 2007;33(5):606-612
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2007;292(6):H3158-H3163
- Article: DIABETES CARE. 2007;30(3):591-596
- Article: ATHEROSCLEROSIS. 2007;190(2):408-415
- Article: BASIC RESEARCH IN CARDIOLOGY. 2007;102(1):80-89
- Article: BASIC RESEARCH IN CARDIOLOGY. 2006;101(3):244-252
- Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2006;47(3):385-390
- Article: DIABETES CARE. 2005;28(6):1495-1497
- Article: CLINICAL SCIENCE. 2005;108(4):357-363
- Article: JOURNAL OF INTERNAL MEDICINE. 2005;257(3):263-271
- Article: BRITISH JOURNAL OF PHARMACOLOGY. 2005;144(6):860-866
- Article: REGULATORY PEPTIDES. 2005;125(1-3):173-177
- Article: ACTA PHYSIOLOGICA. 2005;183(2):151-159
- Article: BRITISH JOURNAL OF PHARMACOLOGY. 2005;144(3):331-337
- Article: SCANDINAVIAN CARDIOVASCULAR JOURNAL. 2004;38(5):270-277
- Article: SCANDINAVIAN CARDIOVASCULAR JOURNAL. 2004;38(5):257-258
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2004;286(5):H1767-H1774
- Article: JOURNAL OF APPLIED PHYSIOLOGY. 2003;95(6):2218-2222
- Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2003;285(4):E864-E870
- Article: EUROPEAN HEART JOURNAL. 2003;24(12):1120-1127
- Article: AMERICAN JOURNAL OF CARDIOLOGY. 2003;91(9):1128-1131
- Article: CLINICAL SCIENCE. 2003;104(2):143-151
- Article: CLINICAL SCIENCE. 2002;103(6):535-542
- Article: NITRIC OXIDE - BIOLOGY AND CHEMISTRY. 2002;7(3):210-216
- Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2002;40(4):564-570
- Article: LIFE SCIENCES. 2002;71(6):679-692
- Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2002;22(4):674-679
- Article: CLINICAL SCIENCE. 2002;102(3):321-327
- Article: BRITISH JOURNAL OF PHARMACOLOGY. 2002;135(1):25-27
- Article: ATHEROSCLEROSIS. 2002;160(1):215-222
- Article: ATHEROSCLEROSIS. 2001;159(1):35-41
- Article: BASIC RESEARCH IN CARDIOLOGY. 2001;96(5):454-462
- Article: JOURNAL OF CARDIOVASCULAR SURGERY. 2001;42(4):489-491
- Article: CARDIOVASCULAR RESEARCH (CVR). 2001;51(1):100-107
- Article: EUROPEAN HEART JOURNAL, SUPPLEMENT. 2001;3(C):C22-C27
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2001;280(3):H1105-H1112
- Article: BRITISH JOURNAL OF PHARMACOLOGY. 2000;131(7):1255-1261
- Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2000;36(3):405-412
- Article: CIRCULATION. 2000;102(9):987-993
- Article: BRITISH JOURNAL OF PHARMACOLOGY. 1999;128(3):637-646
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1999;96(12):6920-6924
- Article: ACTA PHYSIOLOGICA. 1999;165(1):39-44
- Article: CARDIOVASCULAR RESEARCH (CVR). 1998;39(3):674-682
- Article: ACTA PHYSIOLOGICA. 1998;163(4):325-330
- Article: ACTA PHYSIOLOGICA. 1998;163(2):131-137
- Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 1997;29(2):291-296
- Article: ACTA PHYSIOLOGICA. 1997;159(2):147-153
- Article: CIRCULATION. 1996;94(9):2077-2082
- Article: JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM. 1996;57(1-2):13-21
- Article: ACTA PHYSIOLOGICA. 1996;156(1):37-44
- Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 1995;26(5):770-776
- Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1995;283(1-3):161-168
- Article: CARDIOVASCULAR RESEARCH (CVR). 1995;29(6):805-812
- Article: CARDIOVASCULAR RESEARCH (CVR). 1995;29(1):44-49
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Alla övriga publikationer
- Review: JOURNAL OF PHYSIOLOGY. 2023;601(22):4989-5009
- Letter: CIRCULATION: ARRHYTHMIA AND ELECTROPHYSIOLOGY. 2023;16(7):413-414
- Review: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2023;43(5):628-636
- Editorial comment: DRUG DISCOVERY TODAY. 2021;26(8):1773-1775
- Review: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2020;301:207-214
- Review: CARDIOVASCULAR RESEARCH (CVR). 2019;115(11):1596-1605
- Review: CARDIOVASCULAR RESEARCH (CVR). 2019;115(7):1156-1166
- Review: PHARMACOLOGICAL RESEARCH. 2019;141:32-45
- Editorial comment: AGING. 2018;10(12):3643-3644
- Editorial comment: PHYSIOLOGICAL RESEARCH. 2018;67:S1-S3
- Letter: AMERICAN HEART JOURNAL. 2017;187:e7-e8
- Letter: AMERICAN HEART JOURNAL. 2017;185:e2
- Letter: CARDIOVASCULAR RESEARCH (CVR). 2017;113(1):13-14
- Review: CARDIOVASCULAR RESEARCH (CVR). 2013;98(3):334-343
- Editorial comment: CIRCULATION. 2013;127(17):F97-F99
- Published conference paper: LIFE SCIENCES. 2012;91(13-14):723-728
- Published conference paper: LIFE SCIENCES. 2012;91(13-14):507-516
- Letter: DIABETES AND METABOLISM. 2009;35(1):71-73
- Letter: DIABETES CARE. 2008;31(7):e56
- Review: CARDIOVASCULAR RESEARCH (CVR). 2007;76(1):8-18
- Review: LAKARTIDNINGEN. 2003;100(35):2691-2693
- Review: CARDIOVASCULAR RESEARCH (CVR). 2002;55(1):25-37
- Editorial comment: CARDIOVASCULAR RESEARCH (CVR). 2001;49(4):693-694
- Published conference paper: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2000;36(5 Suppl 1):S418-S420
- Published conference paper: ACTA PHYSIOLOGICA. 1999;167(2):151-159
- Review: LAKARTIDNINGEN. 1997;94(12):1069-1073
- Review: CARDIOVASCULAR RESEARCH (CVR). 1997;33(3):518-526
- Published conference paper: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 1995;26:S445-S447
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Anställningar
- Professor/Överläkare, Medicin, Solna, Karolinska Institutet, 2008-
Examina och utbildning
- Docent, Farmakologi, Karolinska Institutet, 1991