Jacopo Fontana

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Publikationer
Populärvetenskap och samverkan

Om mig

Jacopo M. Fontana är klinisk prövningskoordinator vid Karolinska Institutet, där han leder TRAVAGA-studien som undersöker transkutan aurikulär vagusnervstimulering (taVNS) som behandling för reumatoid artrit. Han har över tio års erfarenhet av biomedicinsk forskning, klinisk prövningshantering och vetenskaplig kommunikation, med en bakgrund som spänner över fysiologi, neurovetenskap, immunologi och metabola sjukdomar.
Dr. Fontana har haft forsknings- och koordineringsuppdrag vid Karolinska Institutet, Kungliga Tekniska högskolan (KTH) och Istituto Auxologico Italiano, där han bidragit till projekt om obesitas, neuroinflammation, immunonkologi, njurfysiologi och hörselsystemets biologi.

Artiklar

Journal article: JOURNAL OF CLINICAL MEDICINE. 2025;14(5):1441
Mechanisms and Efficacy of Contrast Therapy for Musculoskeletal Painful Disease: A Scoping Review
Leonardi G; Portaro S; Milardi D; Bonanno F; Sanzarello I; Bruschetta D; Sconza C; Tisano A; Fontana JM; Alito A
Journal article: FRONTIERS IN REHABILITATION SCIENCES. 2025;6:1568280
Effects of whole-body cryostimulation on spinal and shoulder range of motion in individuals with obesity.
Cerfoglio S; Verme F; Fontana JM; Alito A; Galli M; Capodaglio P; Cimolin V
Journal article: JOURNAL OF CLINICAL MEDICINE. 2024;13(24):7728
Whole-Body Cold Stimulation Improves Cardiac Autonomic Control Independently of the Employed Temperature
Solaro N; Giovanelli L; Bianchi L; Pitera P; Verme F; Malacarne M; Pagani M; Fontana JM; Capodaglio P; Lucini D
Journal article: JOURNAL OF CLINICAL MEDICINE. 2024;13(24):7674
Is Whole-Body Cryostimulation Useful in Modulating Spasticity in Adults with Cerebral Palsy? A Case Study
Pitera P; Bigoni M; Prina E; Barrera B; Yavuz DC; Verme F; Fontana JM; Priano L; Mauro A; Capodaglio P
Journal article: JOURNAL OF CLINICAL MEDICINE. 2024;13(23):7365
Sex and Body Mass Index Differences in Changes in Skin Temperature After Repeated Sessions of Whole-Body Cryostimulation
Pitera P; Cancello R; Fontana JM; Verme F; Bouzigon R; Dugue B; Brunani A; Capodaglio P
Journal article: BIOMEDICINES. 2024;12(11):2467
Autonomic Modulation in Parkinson's Disease Using Whole-Body Cryostimulation: A Pilot Study
Pitera P; Cremascoli R; Bianchi L; Borghesi F; Verme F; Cattaldo S; Prina E; Mai S; Cipresso P; Galli F; Fontana JM; Priano L; Mauro A; Capodaglio P
Journal article: JOURNAL OF PERSONALIZED MEDICINE. 2024;14(8):836
Whole-Body Cryostimulation: An Effective Complementary Treatment in Fibromyalgia? A Follow Up Study
Verme F; Majdic N; Modaffari G; Alito A; Scarpa A; Pitera P; Brunani A; Fontana JM; Capodaglio P
Journal article: JOURNAL OF CLINICAL MEDICINE. 2024;13(7):2094
Tackling Kinesiophobia in Chronic Shoulder Pain: A Case Report on the Combined Effect of Pain Education and Whole-Body Cryostimulation
Alito A; Cifalino ME; Fontana JM; Verme F; Pitera P; Capodaglio P
Journal article: JOURNAL OF CLINICAL MEDICINE. 2024;13(7):2003
Whole-Body Cryostimulation in Multiple Sclerosis: A Scoping Review
Alito A; Fontana JM; Tibaldeo EF; Verme F; Pitera P; Miller E; Cremascoli R; Brioschi A; Capodaglio P
Journal article: HEALTHCARE. 2024;12(5):546
Whole Body Cryostimulation: A New Adjuvant Treatment in Central Sensitization Syndromes? An Expert Opinion
Alito A; Verme F; Mercati GP; Pitera P; Fontana JM; Capodaglio P
Journal article: JOURNAL OF CLINICAL MEDICINE. 2024;13(4):993
Whole-Body Cryostimulation as an Adjunctive Treatment for Neurophysiologic Tinnitus and Associated Disorders: Preliminary Evidence from a Case Study
Pitera P; Cremascoli R; Alito A; Bianchi L; Galli F; Verme F; Fontana JM; Bigoni M; Priano L; Mauro A; Capodaglio P
Journal article: HEALTHCARE. 2023;12(1):71
Whole-Body Cryostimulation in Functional Neurological Disorders: A Case Report
Verme F; Fontana JM; Pitera P; Alito A; Saffioti S; Baccalaro G; Zebellin G; Capodaglio P
Journal article: MEDICINA-LITHUANIA. 2023;60(1):22
Whole-Body Cryostimulation, a Complementary Treatment for Phantom Limb Syndrome: Preliminary Evidence from a Case Study
Pitera P; Springhetti I; Alito A; Verme F; Fontana JM; Capodaglio P
Journal article: BIOMEDICINES. 2023;11(11):3092
Whole-Body Cryostimulation in Post-COVID Rehabilitation for Patients with Obesity: A Multidisciplinary Feasibility Study
Fontana JM; Alito A; Pitera P; Verme F; Cattaldo S; Cornacchia M; Mai S; Brunani A; Capodaglio P
Journal article: BIOMEDICINES. 2023;11(6):1594
Effects of Whole-Body Cryostimulation on Pain Management and Disease Activity in Active Rheumatic Polymyalgia: A Case-Report
Verme F; Scarpa A; Varallo G; Pitera P; Capodaglio P; Fontana JM
Journal article: CANCER RESEARCH. 2023;83(7_Supplement):2950
Abstract 2950: CD16A shedding facilitates repetitive targeting of tumor cells by AFM13-armed NK cells
Zambarda C; Guldevall K; Toullec D; Wingert S; Breunig C; Pinto S; Fontana J; Koch J; Önfelt B
Journal article: NUTRIENTS. 2022;14(20):4293
Telomere Length and Mitochondrial DNA Copy Number Variations in Patients with Obesity: Effect of Diet-Induced Weight Loss-A Pilot Study
Cancello R; Rey F; Carelli S; Cattaldo S; Fontana JM; Goitre I; Ponzo V; Merlo FD; Zuccotti G; Bertoli S; Capodaglio P; Bo S; Brunani A
Journal article: JOURNAL OF CLINICAL MEDICINE. 2022;11(15):4324
Is Whole-Body Cryostimulation an Effective Add-On Treatment in Individuals with Fibromyalgia and Obesity? A Randomized Controlled Clinical Trial
Varallo G; Pitera P; Fontana JM; Gobbi M; Arreghini M; Giusti EM; Franceschini C; Plazzi G; Castelnuovo G; Capodaglio P
Journal article: JOURNAL OF THERMAL BIOLOGY. 2022;106:103250
Whole-body cryostimulation in obesity. A scoping review
Fontana JM; Bozgeyik S; Gobbi M; Pitera P; Giusti EM; Dugue B; Lombardi G; Capodaglio P
Journal article: APPLIED SCIENCES-BASEL. 2022;12(10):4830
Whole-Body Cryostimulation: A Rehabilitation Booster in Post-COVID Patients? A Case Series
Pitera P; Gobbi M; Fontana JM; Cattaldo S; Massucci M; Capodaglio P
Journal article: APPLIED SCIENCES-BASEL. 2022;12(9):4794
Whole-Body Cryostimulation in Fibromyalgia: A Scoping Review
Fontana JM; Gobbi M; Pitera P; Giusti EM; Capodaglio P
Article: HEARING RESEARCH. 2022;415:108395
Differential effects of noise exposure between substrains of CBA mice
Versteegh CPC; Tserga EM; Fontana J; Moreno-Paublete R; Sarlus H; Zisiadis G-AR; Cederroth C; Canlon B
Journal article: JOURNAL OF PAIN RESEARCH. 2022;15:3017-3029
Catastrophizing, Kinesiophobia, and Acceptance as Mediators of the Relationship Between Perceived Pain Severity, Self-Reported and Performance-Based Physical Function in Women with Fibromyalgia and Obesity
Varallo G; Suso-Ribera C; Ghiggia A; Veneruso M; Cattivelli R; Usubini AG; Franceschini C; Musetti A; Plazzi G; Fontana JM; Capodaglio P; Castelnuovo G
Journal article: JOURNAL OF REHABILITATION MEDICINE - CLINICAL COMMUNICATIONS. 2022;5:jrmcc00086
WHOLE-BODY CRYOSTIMULATION: A REHABILITATION BOOSTER.
Capodaglio P; Cremascoli R; Piterà P; Fontana JM
Article: CELL DEATH & DISEASE. 2021;12(8):739
Super-resolution microscopy reveals that Na⁺/K⁺-ATPase signaling protects against glucose-induced apoptosis by deactivating Bad
Bernhem K; Fontana JM; Svensson D; Zhang L; Nilsson LM; Scott L; Blom H; Brismar H; Aperia A
Article: JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA. 2019;146(5):3960-3966
Impact of noise exposure on the circadian clock in the auditory system
Fontana JM; Tserga E; Sarlus H; Canlon B; Cederroth C
Article: FASEB JOURNAL. 2019;33(9):10193-10206
Ouabain-regulated phosphoproteome reveals molecular mechanisms for Na⁺, K⁺-ATPase control of cell adhesion, proliferation, and survival
Panizza E; Zhang L; Fontana JM; Hamada K; Svensson D; Akkuratov EE; Scott L; Mikoshiba K; Brismar H; Lehtio J; Aperia A
Journal article: FASEB JOURNAL. 2019;33:567.4
A Novel Concept for Origin and Treatment of Diabetic Nephropathy
Svensson D; Zhang L; Panizza E; Nilsson L; Fontana JM; Moruzzi N; Scott L; Brismar H; Aperia A
Journal article: FASEB JOURNAL. 2019;33:476.21
Ouabain Regulated Phosphoproteome Reveals Molecular Mechanisms Behind Na, K-ATPase Control of Cell Adhesion, Proliferation and Survival
Panizza E; Svensson D; Zhang L; Fontana JM; Akkuratov E; Scott L; Brismar H; Lehtio J; Aperia A
Article: FASEB JOURNAL. 2019;33(3):4089-4096
Spontaneous calcium activity in metanephric mesenchymal cells regulates branching morphogenesis in the embryonic kidney
Fontana JM; Khodus GR; Unnersjo-Jess D; Blom H; Aperia A; Brismar H
Article: INTERNATIONAL JOURNAL OF NANOMEDICINE. 2017;12:8615-8629
Transport and release of colloidal 3-mercaptopropionic acid-coated CdSe-CdS/ZnS core-multishell quantum dots in human umbilical vein endothelial cells
Fontana JM; Yin H; Chen Y; Florez R; Brismar H; Fu Y
Article: INTERNATIONAL JOURNAL OF NANOMEDICINE. 2017;12:2781-2792
Quantum dots modulate intracellular Ca²⁺ level in lung epithelial cells
Yin H; Fontana JM; Solandt J; Jussi JI; Xu H; Brismar H; Fu Y
Journal article: FASEB JOURNAL. 2015;29
Apoptosis caused by excessive mitochondrial albumin uptake in renal cells is initiated by increased mitochondrial calcium concentration
Fontana J; Fritz N; Brismar H; Aperia A
Journal article: FASEB JOURNAL. 2014;28(S1)
Ca2+ shuttling between endoplasmic reticulum and mitochondria underlying ouabain‐triggered Ca2+ oscillations (1097.10)
Fontana J; Kruusmägi M; Brismar H; Aperia A
Journal article: CURRENT SIGNAL TRANSDUCTION THERAPY. 2012;7(2):161-176
Hematopoietic Progenitor and Stem Cells Circulate by Surfing on Intracellular Ca²⁺ Waves: A Novel Target for Cell-based Therapy and Anti-cancer Treatment?
Moccia F; Bonetti E; Dragoni S; Fontana J; Lodola F; Berra Romani R; Laforenza U; Rosti V; Tanzi F
Article: STEM CELLS AND DEVELOPMENT. 2010;19(12):1967-1981
Store-Operated Ca²⁺ Entry Is Expressed in Human Endothelial Progenitor Cells
Sanchez-Hernandez Y; Laforenza U; Bonetti E; Fontana J; Dragoni S; Russo M; Avelino-Cruz JE; Schinelli S; Testa D; Guerra G; Rosti V; Tanzi F; Moccia F
Article: BIOLOGY OF THE CELL. 2010;102(8):457-467
Solute transporters and aquaporins are impaired in celiac disease
Laforenza U; Micelli E; Gastaldi G; Scaffino MF; Ventura U; Fontana JM; Orsenigo MN; Corazza GR
Article: REJUVENATION RESEARCH. 2010;13(1):23-26
Preliminary Evidence of a Genetic Association Between Chromosome 9p21.3 and Human Longevity
Emanuele E; Fontana JM; Minoretti P; Geroldi D
Article: JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY. 2010;2010:264704-8
Aquaporin-6 Expression in the Cochlear Sensory Epithelium Is Downregulated by Salicylates
Perin P; Tritto S; Botta L; Fontana JM; Gastaldi G; Masetto S; Tosco M; Laforenza U
Article: ARCHIVES OF MEDICAL RESEARCH. 2008;39(3):320-325
The -374T/A RAGE polymorphism protects against future cardiac events in nondiabetic patients with coronary artery disease
Falcone C; Geroldi D; Buzzia MP; Ernanuele E; Yilmaz Y; Fontana JM; Vignali L; Boiocchi C; Sbarsi I; Cuccia M
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Preprint: PREPRINTS.ORG. 2023
Whole-Body Cryostimulation, a Complementary Treatment for Phantom Limb Syndrome: Preliminary Evidence from a Case Study
Piterà P; Springhetti I; Alito A; Verme F; Fontana JM; Capodaglio P
Preprint: PREPRINTS.ORG. 2023
A Feasibility Study on a Multidisciplinary Rehabilitation Program Including Whole-Body Cryostimulation in Patients With Obesity and Post-COVID Condition
Fontana JM; Alito A; Piterà P; Verme F; Cattaldo S; Cornacchia M; Mai S; Brunani A; Capodaglio P
Preprint: PREPRINTS.ORG. 2023
Whole-Body Cryostimulation in Functional Neurological Disorders: A Case-Report
Verme F; Fontana JM; Piterà P; Alito A; Saffioti S; Baccalaro G; Zebellin G; Capodaglio P
Preprint: PREPRINTS.ORG. 2023
Effects of Whole-Body Cryostimulation on pain management and disease activity in active Rheumatic Polymyalgia: a Case-Report
Verme F; Scarpa A; Varallo G; Piterà P; Capodaglio P; Fontana JM
Meeting abstract: CANCER RESEARCH. 2023;83(7):4578
Miniaturized and multiplexed evaluation of NK cell cytotoxicity and infiltration in patient-derived sarcoma spheroids using a novel multichambered microwell chip
Carannante V; Sandstrom N; Olofsson K; Neo SY; Sandoz PA; Van Ooijen H; Verron Q; Fontana J; Toullec D; Moussaud-Lamodiere E; Seashore-Ludlow B; Frisk T; Takai M; Ostling P; Haglund F; Lundqvist A; Wiklund M; Onfelt B
Conference publication: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2021;9:A938
THE BISPECIFIC INNATE CELL ENGAGERS AFM13 (CD30/ CD16A) AND AFM24 (EGFR/CD16A) INCREASE THE FRACTION OF TUMOR TARGET-RESPONSIVE NK CELLS AND BOOST SERIAL KILLING
Zambarda C; Guldevall K; Zambarda C; Guldevall K; Breunig C; Toullec D; Fontana J; Pinto S; Pahl J; Wingert S; Koch J; Oenfelt B
Review: HEARING RESEARCH. 2019;377:53-60
Circadian integration of inflammation and glucocorticoid actions: Implications for the cochlea
Sarlus H; Fontana JM; Tserga E; Meltser I; Cederroth CR; Canlon B
Conference publication: FASEB JOURNAL. 2017;31
Mapping the apoptotic process with super resolution microscopy in kidney cells challenged with high glucose
Bernhem K; Zhang L; Fontana J; Nilsson L; Scott L; Brismar H; Aperia A
Conference publication: FASEB JOURNAL. 2016;30
Role of calcium signaling for GDNF secretion, ureter branching and early nephron formation
Fontana JM; Jess DU; Blom H; Brismar H; Aperia A
Review: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2016;310(7):C491-C495
Na⁺-K⁺-ATPase, a new class of plasma membrane receptors
Aperia A; Akkuratov EE; Fontana JM; Brismar H
Conference publication: FASEB JOURNAL. 2015;29
Pyk2-Dependent Phosphorylation of Mitochondrial Ca²⁺ Uniporter Modulates Mitochondrial Ca²⁺ Uptake
O-Uchi J; Hurst S; Fontana J; Mishra J; Xu X; Fu D; Jhun BS; Aperia A; Sheu S-S
Conference publication: MOLECULAR BIOLOGY OF THE CELL. 2015;26
Ouabain, a Na, K-ATPase ligand, intervenes with the onset of glucose-triggered apoptosis
Fontana JM; Bernhem K; Zhang L; Nilsson L; Blom H; Brismar H; Aperia A
Review: FEBS JOURNAL. 2013;280(21):5450-5455
Calcium oscillations triggered by cardiotonic steroids
Fontana JM; Burlaka I; Khodus G; Brismar H; Aperia A
Conference publication: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2010;40:70
Aquaporin-7 and-10 represent pathways for glycerol efflux from human adipocytes
Laforenza U; Scaffino MF; Fontana JM; Gastaldi G

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