Iva Gunnarsson

Iva Gunnarsson

Adjungerad Professor
E-postadress: iva.gunnarsson@ki.se
Besöksadress: ,
Postadress: K2 Medicin, Solna, K2 Reuma Antovic A, 171 77 Stockholm
Del av:

Om mig

  • *Research focus*: We perform translational studies on two autoimmune
    diseases, systemic lupus erythematos (SLE) and ANCA-associated vasculitis
    (AAV) with a special focus on renal involvement. We have identified promising
    biomarkers that reflect renal activity and damage development,
    histopathological studies in effects of therapy, and participated in
    genetical studies. We have collected large cohorts with biomaterial from the
    time-point of renal biopsies, both before and after immunosuppressive
    treatment.
    I am the leader of studies regarding the use of biologics (rituximab,
    belimumab) in SLE and in principal investigator for a large cohort of AAV,
    performed in collaboration with nephrology at Karolinska. I also have a
    research interest in SLE pregnancy and males with SLE.
    *Introduction/history*: I am a senior consultant in Rheumatology and work
    half-time in the clinic, mainly with inflammatory systemic diseases and
    half-time with research as adjunct professor in rheumatology. I defended my
    thesis in 1999.
    *Major lines of research:* Systemic lupus erythematosus and ANCA-associated
    vasculitis, renal involvement, use of biologics, biomarkers
    *Team members: *
    Agneta Zickert, rheumatologist, postdoc on studies on lupus nephritis
    Francesca Faustini, rheumatologist, PhD in SLE research
    Anna Juto, PhD student in vasculitis research
    Jakob Gerhardsson, PhD student in SLE research
    Charikleia Chrysostomou, nephrologist, pre-PhD student in SLE research
    Peter Hemmingsson, nephrologist, pre-PhD student in vasculitis research
    Linnea Karlsson, pre-PhD student in renal SLE research
    *Selected publications:*
    1) Resorption of immune deposits in membranous lupus nephritis following
    rituximab versus conventional immunosuppressive treatment Agneta
    Zickert , Klas Lannfelt , Jan Schmidt Mende, Birgitta Sundelin, and *Iva
    Gunnarsson*. Rheumatology 2020
    1) Myriam Martin, Rebecca Trattner Evetovics, Sara C. Nilsson, Albin Björk,
    Agneta Zickert, Anna M. Blom and *Iva Gunnarsson* Plasma C4d correlates
    with C4d deposition in kidneys and with treatment response in systemic
    lupus erythematosus with renal involvement. Frontiers Immunology 2020
    1) Antovic A, Mobarrez F, Manojlovic M, Soutari N, De Porta Baggemar
    V, Nordin A, Bruchfeld A, Vojinovic J, * Gunnarsson I.
    *Microparticles Expressing Myeloperoxidase and Complement C3a and C5a as
    Markers of Renal Involvement in Antineutrophil Cytoplasmic
    Antibody-associated Vasculitis. The Journal of rheumatology 2020 47;5
    714-721
    1) Arnaud L, Nordin A, Lundholm H, Svenungsson E, Hellbacher E, Wikner
    J, Zickert A, * Gunnarsson I. *Effect of Corticosteroids and
    Cyclophosphamide on Sex Hormone Profiles in Male Patients With Systemic
    Lupus Erythematosus or Systemic Sclerosis. Arthritis & rheumatology
    (Hoboken, N.J.) 2017 69;6 1272-1279
    1) Gerhardsson J, Sundelin B, Zickert A, Padyukov L, Svenungsson E,
    * Gunnarsson I. *Histological antiphospholipid-associated nephropathy
    versus lupus nephritis in patients with systemic lupus erythematosus: an
    observational cross-sectional study with longitudinal follow-up.
    Arthritis research & therapy 2015 17; 109-

Artiklar

Alla övriga publikationer

Anställningar

  • Adjungerad Professor, Medicin, Solna, Karolinska Institutet, 2019-2027

Examina och utbildning

  • Docent, Reumatologi, Karolinska Institutet, 2011
  • MEDICINE DOKTORSEXAMEN, Institutionen för medicin, Solna, Karolinska Institutet, 1999

Handledning

  • Handledning till doktorsexamen

    • Sara Brolin, Educational needs, quality of life, and health care support in persons with systemic rheumatic disease, 2023-
    • Annika Granath, Patients perspective in vasculitis, 2021-
    • Charikleia Chrysostomou

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