Ingo Leibiger

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2024;(205)

In Vivo Imaging of Liver Spheroids Engrafted in the Anterior Chamber of the Mouse Eye

Lazzeri-Barcelo F; Ciardo P; Leibiger B; Leibiger IB; Berggren P-O; Moruzzi N
Article: NATURE COMMUNICATIONS. 2024;15(1):779

Using deep learning to quantify neuronal activation from single-cell and spatial transcriptomic data

Bahl E; Chatterjee S; Mukherjee U; Elsadany M; Vanrobaeys Y; Lin L-C; Mcdonough M; Resch J; Giese KP; Abel T; Michaelson JJ
Article: CELL TRANSPLANTATION. 2024;33:09636897241241995

Transplantation and Noninvasive Longitudinal In Vivo Imaging of Parathyroid Cells: A Proof-of-Concept Study

Branstrom R; van Krieken PP; Frobom R; Juhlin CC; Shabo I; Leibiger B; Leibiger IB; Berggren P-O; Aspinwall CA
Article: BIOMOLECULES. 2023;13(6):885

Multiple Inositol Polyphosphate Phosphatase Compartmentalization Separates Inositol Phosphate Metabolism from Inositol Lipid Signaling

Yu J; Leibiger B; Yang S-N; Shears SBB; Leibiger IBB; Berggren P-O; Barker CJJ
Article: METHODS IN MOLECULAR BIOLOGY. 2023;2592:21-36

Uncommon Transplantation Sites: Transplantation of Islets and Islet Organoids in the Anterior Chamber of the Eye of Rodents and Monkeys.

Moede T; Tun SBB; Leibiger IB; Berggren P-O
Article: LIFE SCIENCE ALLIANCE. 2022;5(12):e202201505

Mitochondrial impairment and intracellular reactive oxygen species alter primary cilia morphology

Moruzzi N; Valladolid-Acebes I; Kannabiran SA; Bulgaro S; Burtscher I; Leibiger B; Leibiger IB; Berggren P-O; Brismar K
Article: BIOCHEMISTRY AND BIOPHYSICS REPORTS. 2022;30:101260

Inward and outward currents of native and cloned K(ATP) channels (Kir6.2/SUR1) share single-channel kinetic properties

Branstrom R; Berglund E; Frobom R; Leibiger IB; Leibiger B; Aspinwall CA; Larsson O; Berggren P-O
Article: CELL TRANSPLANTATION. 2022;31:9636897221098038-096368972210980

Local Dexamethasone Administration Delays Allogeneic Islet Graft Rejection in the Anterior Chamber of the Eye of Non-Human Primates

Tun SBB; Chua M; Tan GSW; Leibiger I; Ali Y; Barathi VA; Berggren P-O
Article: SCIENTIFIC REPORTS. 2021;11(1):21539

Expression of truncated Kir6.2 promotes insertion of functionally inverted ATP-sensitive K⁺ channels

Heitz BA; Branstrom R; Yang W; Huang Y; Moede T; Leibiger IB; Leibiger B; Chen LQ; Yu J; Yang S-N; Larsson O; Saavedra SS; Berggren P-O; Aspinwall CA
Article: METABOLITES. 2021;11(6):387

Ectopic Leptin Production by Intraocular Pancreatic Islet Organoids Ameliorates the Metabolic Phenotype of ob/ob Mice

Leibiger B; Moede T; Valladolid-Acebes I; Paschen M; Visa M; Leibiger IB; Berggren P-O
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2021;25(10):4800-4813

Tissue-specific expression of insulin receptor isoforms in obesity/type 2 diabetes mouse models

Moruzzi N; Lazzeri-Barcelo F; Valladolid-Acebes I; Moede T; Paschen M; Leibiger B; Berggren P-O; Leibiger IB
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(4):1813

Human Islet Microtissues as an In Vitro and an In Vivo Model System for Diabetes

Mir-Coll J; Moede T; Paschen M; Neelakandhan A; Valladolid-Acebes I; Leibiger B; Biernath A; Ammala C; Leibiger IB; Yesildag B; Berggren P-O
Article: SCIENTIFIC REPORTS. 2020;10(1):20145

Glucokinase intrinsically regulates glucose sensing and glucagon secretion in pancreatic alpha cells

Moede T; Leibiger B; Sanchez PV; Dare E; Kohler M; Muhandiramlage TP; Leibiger IB; Berggren P-O
Article: FASEB JOURNAL. 2020;34(1):945-959

In vivo Ca²⁺ dynamics in single pancreatic β cells

Jacob S; Kohler M; Troster P; Visa M; Garcia-Prieto CF; Alanentalo T; Moede T; Leibiger B; Leibiger IB; Berggren P-O
Article: NATURE COMMUNICATIONS. 2019;10(1):3700

Structural basis for delta cell paracrine regulation in pancreatic islets

Arrojo e Drigo R; Jacob S; Garcia-Prieto CF; Zheng X; Fukuda M; Hoa TTN; Stelmashenko O; Martins Pecanha FL; Rodriguez-Diaz R; Bushong E; Deerinck T; Phan S; Ali Y; Leibiger I; Chua M; Boudier T; Song S-H; Graf M; Augustine GJ; Ellisman MH; Berggren P-O
Article: NATURE COMMUNICATIONS. 2019;10(1):2692

SMPDL3b modulates insulin receptor signaling in diabetic kidney disease

Mitrofanova A; Mallela SK; Ducasa GM; Yoo TH; Rosenfeld-Gur E; Zelnik ID; Molina J; Santos JV; Ge M; Sloan A; Kim JJ; Pedigo C; Bryn J; Volosenco I; Faul C; Zeidan YH; Hernandez CG; Mendez AJ; Leibiger I; Burke GW; Futerman AH; Barisoni L; Ishimoto Y; Inagi R; Merscher S; Fornoni A
Article: FASEB JOURNAL. 2019;33(1):204-218

Diet-induced -cell insulin resistance results in reversible loss of functional -cell mass

Paschen M; Moede T; Valladolid-Acebes I; Leibiger B; Moruzzi N; Jacob S; Garcia-Prieto CF; Brismar K; Leibiger IB; Berggren P-O
Article: CELL METABOLISM. 2018;27(3):549-558.e4

Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point

Rodriguez-Diaz R; Molano RD; Weitz JR; Abdulreda MH; Berman DM; Leibiger B; Leibiger IB; Kenyon NS; Ricordi C; Pileggi A; Caicedo A; Berggren P-O
Article: CELL REPORTS. 2017;20(6):1490-1501

Pancreatic Islet Blood Flow Dynamics in Primates

Diez JA; Arrojo e Drigo R; Zheng X; Stelmashenko OV; Chua M; Rodriguez-Diaz R; Fukuda M; Kohler M; Leibiger I; Tun SBB; Ali Y; Augustine GJ; Barathi VA; Berggren P-O
Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2016;27(4):1029-1041

Nephrin Contributes to Insulin Secretion and Affects Mammalian Target of Rapamycin Signaling Independently of Insulin Receptor

Villarreal R; Mitrofanova A; Maiguel D; Morales X; Jeon J; Grahammer F; Leibiger IB; Guzman J; Fachado A; Yoo TH; Katin AB; Gellermann J; Merscher S; Burke GW; Berggren P-O; Oh J; Huber TB; Fornoni A
Article: SCIENTIFIC REPORTS. 2016;6:21448

Non-invasive cell type selective in vivo monitoring of insulin resistance dynamics

Paschen M; Moede T; Leibiger B; Jacob S; Bryzgalova G; Leibiger IB; Berggren P-O
Article: CELL REPORTS. 2015;13(1):15-22

PI3K-C2α Knockdown Results in Rerouting of Insulin Signaling and Pancreatic Beta Cell Proliferation

Leibiger B; Moede T; Paschen M; Yunn N-O; Lim JH; Ryu SH; Pereira T; Berggren P-O; Leibiger IB
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(20):E2611-E2619

Apolipoprotein CIII links islet insulin resistance to β-cell failure in diabetes

Avall K; Ali Y; Leibiger IB; Leibiger B; Moede T; Paschen M; Dicker A; Dare E; Kohler M; Ilegems E; Abdulreda MH; Graham M; Crooke RM; Tay VSY; Refai E; Nilsson SK; Jacob S; Selander L; Berggren P-O; Juntti-Berggren L
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2015;290(5):2812-2821

The Paired Basic Amino Acid-cleaving Enzyme 4 (PACE4) Is Involved in the Maturation of Insulin Receptor Isoform B AN OPPORTUNITY TO REDUCE THE SPECIFIC INSULIN RECEPTOR-DEPENDENT EFFECTS OF INSULIN-LIKE GROWTH FACTOR 2 (IGF2)

Kara I; Poggi M; Bonardo B; Govers R; Landrier J-F; Tian S; Leibiger I; Day R; Creemers JWM; Peiretti F
Article: NATURE COMMUNICATIONS. 2014;5:5308

Ciliary dysfunction impairs beta-cell insulin secretion and promotes development of type 2 diabetes in rodents

Gerdes JM; Christou-Savina S; Xiong Y; Moede T; Moruzzi N; Karlsson-Edlund P; Leibiger B; Leibiger IB; Ostenson C-G; Beales PL; Berggren P-O
Article: CELL. 2014;158(1):41-53

Adipsin Is an Adipokine that Improves β Cell Function in Diabetes

Lo JC; Ljubicic S; Leibiger B; Kern M; Leibiger IB; Moede T; Kelly ME; Bhowmick DC; Murano I; Cohen P; Banks AS; Khandekar MJ; Dietrich A; Flier JS; Cinti S; Blueher M; Danial NN; Berggren P-O; Spiegelman BM
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(51):20581-20586

Reporter islets in the eye reveal the plasticity of the endocrine pancreas

Ilegems E; Dicker A; Speier S; Sharma A; Bahow A; Edlund PK; Leibiger IB; Berggren P-O
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(52):21456-21461

Noninvasive in vivo model demonstrating the effects of autonomic innervation on pancreatic islet function

Rodriguez-Diaz R; Speier S; Molano RD; Formoso A; Gans I; Abdulreda MH; Cabrera O; Molina J; Fachado A; Ricordi C; Leibiger I; Pileggi A; Berggren P-O; Caicedo A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(51):20925-20930

Glucagon regulates its own synthesis by autocrine signaling

Leibiger B; Moede T; Muhandiramlage TP; Kaiser D; Sanchez PV; Leibiger IB; Berggren P-O
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(34):28932-28942

Dynamin-mediated Nephrin Phosphorylation Regulates Glucose-stimulated Insulin Release in Pancreatic Beta Cells

Jeon J; Leibiger I; Moede T; Walter B; Faul C; Maiguel D; Villarreal R; Guzman J; Berggren P-O; Mundel P; Ricordi C; Merscher-Gomez S; Fornoni A
Article: INTEGRATIVE BIOLOGY. 2012;4(2):209-219

One-step purification of functional human and rat pancreatic alpha cells

Koehler M; Dare E; Ali MY; Rajasekaran SS; Moede T; Leibiger B; Leibiger IB; Tibell A; Juntti-Berggren L; Berggren P-O
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(31):12863-12868

High-resolution, noninvasive longitudinal live imaging of immune responses

Abdulreda MH; Faleo G; Molano RD; Lopez-Cabezas M; Molina J; Tan Y; Echeverria OAR; Zahr-Akrawi E; Rodriguez-Diaz R; Edlund PK; Leibiger I; Bayer AL; Perez V; Ricordi C; Caicedo A; Pileggi A; Berggren P-O
Article: FASEB JOURNAL. 2010;24(6):1824-1837

Insulin-feedback via PI3K-C2α activated PKBα/Akt1 is required for glucose-stimulated insulin secretion

Leibiger B; Moede T; Uhles S; Barker CJ; Creveaux M; Domin J; Berggren P-O; Leibiger IB
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):111-115

Novel aspects on pancreatic beta-cell signal-transduction

Leibiger IB; Brismar K; Berggren P-O
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2009;158(2):486-493

Pals-associated tight junction protein functionally links dopamine and angiotensin II to the regulation of sodium transport in renal epithelial cells

Chen Z; Leibiger I; Katz AI; Bertorello AM
Article: CANCER RESEARCH. 2008;68(17):7156-7164

CREB3L2-PPARγ fusion mutation identifies a thyroid signaling pathway regulated by intramembrane proteolysis

Lui W-O; Zeng L; Rehmann V; Deshpande S; Tretiakova M; Kaplan EL; Leibiger I; Leibiger B; Enberg U; Hoog A; Larsson C; Kroll TG
Article: NATURE MEDICINE. 2008;14(5):574-578

Noninvasive in vivo imaging of pancreatic islet cell biology

Speier S; Nyqvist D; Cabrera O; Yu J; Molano RD; Pileggi A; Moede T; Kohler M; Wilbertz J; Leibiger B; Ricordi C; Leibiger IB; Caicedo A; Berggren P-O
Article: NATURE PROTOCOLS. 2008;3(8):1278-1286

Noninvasive high-resolution in vivo imaging of cell biology in the anterior chamber of the mouse eye

Speier S; Nyqvist D; Koehler M; Caicedo A; Leibiger IB; Berggren P-O
Article: EXPERIMENTAL DIABETES RESEARCH. 2008;2008:865850

Real-Time Monitoring of Apoptosis by Caspase-3-Like Protease Induced FRET Reduction Triggered by Amyloid Aggregation

Paulsson JF; Schultz S; Kohler M; Leibiger I; Berggren P-O; Westermark GT
Article: DIABETOLOGIA. 2007;50(8):1670-1677

Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters:: indications for a long-chain acyl-CoA ester binding motif

Braenstroem R; Leibiger IB; Leibiger B; Klement G; Nilsson J; Arhem P; Aspinwall CA; Corkey BE; Larsson O; Berggren R-O
Article: FASEB JOURNAL. 2007;21(7):1609-1621

Selective gene activation by spatial segregation of insulin receptor B signaling

Uhles S; Moede T; Leibiger B; Berggren P-O; Leibiger IB
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2006;63(24):3055-3060

Proinsulin C-peptide and insulin:: Limited pattern similarities of interest in inter-peptide interactions but no C-peptide effect on insulin and IGF-1 receptor signaling

Henriksson M; Johansson J; Moede T; Leibiger I; Shafqat J; Berggren P-O; Jornvall H
Article: FEBS LETTERS. 2006;580(21):5067-5070

FRET analysis reveals a critical conformational change within the Na,K-ATPase α1 subunit N-terminus during GPCR-dependent endocytosis

Efendiev R; Cinelli AR; Leibiger IB; Bertorello AM; Pedemonte CH
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2006;35(1):127-132

Phosphorylation of adaptor protein-2 μ2 is essential for Na⁺,K⁺-ATPase endocytosis in response to either G protein-coupled receptor or reactive oxygen species

Chen Z; Krmar RT; Dada L; Efendiev R; Leibiger IB; Pedemonte CH; Katz AI; Sznajder JI; Bertorello AM
Article: ENDOCRINE-RELATED CANCER. 2006;13(2):509-523

Loss of parafibromin expression in a subset of parathyroid adenomas

Juhlin C; Larsson C; Yakoleva T; Leibiger I; Leibiger B; Alimov A; Weber G; Hoog A; Villablanca A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005;338(3):1455-1459

Monomeric G-protein, Rhes, is not an imidazoline-regulated protein in pancreatic β-cells

Sharoyko VV; Zaitseva II; Varsanyi M; Portwood N; Leibiger B; Leibiger I; Berggren PO; Efendic S; Zaitsev SV
Article: CELL. 2004;119(2):273-284

Removal of Ca²⁺ channel β₃ Subunit enhances Ca²⁺ oscillation frequency and insulin exocytosis

Berggren PO; Yang SN; Murakami M; Efanov AM; Uhles S; Köhler M; Moede T; Fernström A; Appelskog LB; Aspinwall CA; Zaitsev SV; Larsson O; de Vargas LM; Fecher-Trost C; Weissgerber P; Ludwig A; Leibiger B; Juntti-Berggren L; Barker CJ; Gromada J; Freichel M; Leibiger IB; Flockerzi V
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(27):10090-10094

Apolipoprotein CIII promotes Ca²⁺-dependent β cell death in type 1 diabetes

Juntti-Berggren L; Refai E; Appelskog I; Andersson M; Imreh G; Dekki N; Uhles S; Yu L; Griffiths WJ; Zaitsev S; Leibiger I; Yang SN; Olivecrona G; Jörnvall H; Berggren PO
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(23):24152-24162

Interferon α-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway

Thyrell L; Hjortsberg L; Arulampalam V; Panaretakis T; Uhles S; Dagnell M; Zhivotovsky B; Leibiger I; Grandér D; Pokrovskaja K
Article: JOURNAL OF CELL BIOLOGY. 2003;163(6):1327-1337

Isoform-specific insulin receptor signaling involves different plasma membrane domains

Uhles S; Moede T; Leibiger B; Berggren PO; Leibiger IB
Article: DIABETES. 2003;52(12):2896-2904

Oxidative stress induces nucleo-cytoplasmic translocation of pancreatic transcription factor PDX-1 through activation of c-Jun NH(2)-terminal kinase.

Kawamori D; Kajimoto Y; Kaneto H; Umayahara Y; Fujitani Y; Miyatsuka T; Watada H; Leibiger IB; Yamasaki Y; Hori M
Article: DIABETES. 2003;52(12):2943-2950

On-line monitoring of apoptosis in insulin-secreting cells

Köhler M; Zaitsev SV; Zaitseva II; Leibiger B; Leibiger IB; Turunen M; Kapelioukh IL; Bakkman L; Appelskog IB; de Monvel JB; Imreh G; Berggren PO
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(47):46210-46218

Cytosolic multiple inositol polyphosphate phosphatase in the regulation of cytoplasmic free Ca²⁺ concentration

Yu J; Leibiger B; Yang SN; Caffery JJ; Shears SB; Leibiger IB; Barker CJ; Berggren PO
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(45):44753-44757

Rapid association of protein kinase C-ε with insulin granules is essential for insulin exocytosis

Mendez CF; Leibiger IB; Leibiger B; Hoy M; Gromada J; Berggren PO; Bertorello AM
Article: MOLECULAR BIOLOGY OF THE CELL. 2003;14(3):1149-1157

Analysis of Na⁺,K⁺-ATPase motion and incorporation into the plasma membrane in response to G protein-coupled receptor signals in living cells

Bertorello AM; Komarova Y; Smith K; Leibiger IB; Efendiev R; Pedemonte CH; Borisy G; Sznajder JI
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(46):44108-44114

Relevance of dopamine signals anchoring dynamin-2 to the plasma membrane during Na⁺,K⁺-ATPase endocytosis

Efendiev R; Yudowski GA; Zwiller J; Leibiger B; Katz AI; Berggren PO; Pedemonte CH; Leibiger IB; Bertorello AM
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2002;99(10):6773-6777

Inositol hexakisphosphate promotes dynamin mediated endocytosis

Hoy M; Efanov AM; Bertorello AM; Zaitsev SV; Olsen HL; Bokvist K; Leibiger B; Leibiger IB; Zwiller J; Berggren PO; Gromada J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(19):17108-17111

Tyrosine 537 within the Na⁺,K⁺-ATPase α-subunit is essential for AP-2 binding and clathrin-dependent endocytosis

Doné SC; Leibiger IB; Efendiev R; Katz AI; Leibiger B; Berggren PO; Pedemonte CH; Bertorello AM
Article: MAMMALIAN GENOME. 2002;13(1):20-23

Characterization of a putative murine mitochondrial transporter homology of hMRS3/4

Li FY; Leibiger B; Leibiger I; Larsson C
Article: FEBS LETTERS. 2001;494(1-2):79-84

Characterization of a novel human putative mitochondrial transporter homologous to the yeast mitochondrial RNA splicing proteins 3 and 4

Li FY; Nikali K; Gregan J; Leibiger I; Leibiger B; Schweyen R; Larsson C; Suomalainen A
Article: MOLECULAR CELL. 2001;7(3):559-570

Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic β cells

Leibiger B; Leibiger IB; Moede T; Kemper S; Kulkarni RN; Kahn CR; de Vargas LM; Berggren PO
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(39):30153-30156

Glucose-stimulated insulin biosynthesis depends on insulin-stimulated insulin gene transcription

Leibiger B; Wåhlander K; Berggren PO; Leibiger IB
Article: FEBS LETTERS. 1999;461(3):229-234

Identification of a nuclear localization signal, RRMKWKK, in the homeodomain transcription factor PDX-1

Moede T; Leibiger B; Pour HG; Berggren PO; Leibiger IB
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1999;96(18):10164-10169

Syntaxin 1 interacts with the L_D subtype of voltage-gated Ca²⁺ channels in pancreatic β cells

Yang SN; Larsson O; Bränström R; Bertorello AM; Leibiger B; Leibiger IB; Moede T; Köhler M; Meister B; Berggren PO
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1998;273(47):31395-31400

Long chain coenzyme A esters activate the pore-forming subunit (Kir6.2) of the ATP-regulated potassium channel

Bränström R; Leibiger IB; Leibiger B; Corkey BE; Berggren PO; Larsson O
Article: EMBO JOURNAL. 1998;17(17):5048-5058

Cysteine string protein (CSP) is an insulin secretory granule-associated protein regulating β-cell exocytosis

Brown H; Larsson O; Bränström R; Yang SN; Leibiger B; Leibiger I; Fried G; Moede T; Deeney JT; Brown GR; Jacobsson G; Rhodes CJ; Braun JEA; Scheller RH; Corkey BE; Berggren PO; Meister B
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998;95(16):9307-9312

Short-term regulation of insulin gene transcription by glucose

Leibiger B; Moede T; Schwarz T; Brown GR; Köhler M; Leibiger IB; Berggren PO
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998;95(11):6145-6150

In situ activation of the type 2 ryanodine receptor in pancreatic beta cells requires cAMP-dependent phosphorylation

Islam MS; Leibiger I; Leibiger B; Rossi D; Sorrentino V; Ekström TJ; Westerblad H; Andrade FH; Berggren PO
Article: MOLECULAR CELL. 1998;1(6):933-938

Exocytosis of insulin promotes insulin gene transcription via the insulin receptor PI-3 kinase p70 s6 kinase and CaM kinase pathways

Leibiger IB; Leibiger B; Moede T; Berggren PO
Article: MAMMALIAN GENOME. 1998;9(4):310-311

Mapping of the human Ca²⁺ channel β₄ subunit to 2q22-23 and its expression in developing mouse

Betz R; Leibiger B; Farnebo F; Lagercrantz S; Piehl F; Leibiger I; Larsson C
Article: DIABETOLOGIA. 1996;39(10):1165-1172

Dual function of the intron of the rat insulin I gene in regulation of gene expression

Damert A; Leibiger B; Leibiger IB
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Alla övriga publikationer

Review: ADVANCES IN BIOLOGICAL REGULATION. 2023;87:100919

Novel aspects of intra-islet communication: Primary cilia and filopodia

Moruzzi N; Leibiger B; Barker CJ; Leibiger IB; Berggren P-O
Review: DIABETOLOGIA. 2020;63(10):2064-2075

Alpha cell regulation of beta cell function

Moede T; Leibiger IB; Berggren P-O
Corrigendum: NATURE COMMUNICATIONS. 2019;10(1):4218

Structural basis for delta cell paracrine regulation in pancreatic islets (vol 10, 3700, 2019)

Arrojo e Drigo R; Jacob S; Garcia-Prieto CF; Zheng X; Fukuda M; Hoa TTN; Stelmashenko O; Martins Pecanha FL; Rodriguez-Diaz R; Bushong E; Deerinck T; Phan S; Ali Y; Leibiger I; Chua M; Boudier T; Song S-H; Graf M; Augustine GJ; Ellisman MH; Berggren P-O
Review: PHARMACOLOGY & THERAPEUTICS. 2018;185:86-98

Mechanistic understanding of insulin receptor modulation: Implications for the development of anti-diabetic drugs

Yunn N-O; Kim J; Kim Y; Leibiger I; Berggren P-O; Ryu SH
Review: MOLECULAR METABOLISM. 2017;6(9):1002-1009

Intraocular in vivo imaging of pancreatic islet cell physiology/pathology

Leibiger IB; Berggren P-O
Editorial comment: NATURE MEDICINE. 2015;21(1):14-16

Regulation of glucose homeostasis using radiogenetics and magnetogenetics in mice

Leibiger IB; Berggren P-O
Review: ADVANCES IN BIOLOGICAL REGULATION. 2013;53(1):156-163

The pancreatic islet as a signaling hub.

Barker CJ; Leibiger IB; Berggren P-O
Editorial comment: MOLECULAR METABOLISM. 2013;2(1):1-2

You are what you eat-Do not blame your mother

Leibiger IB; Ilegems E; Berggren P-O
Review: ACTA PHYSIOLOGICA. 2012;204(2):178-185

Non-invasive in vivo imaging of pancreatic ß-cell function and survival - a perspective

Leibiger IB; Caicedo A; Berggren P-O
Review: ANNUAL REVIEW OF NUTRITION. 2008;28:233-251

Insulin signaling in the pancreatic β-cell

Leibiger IB; Leibiger B; Berggren P-O
Published conference paper: NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. 2006;16:S7-10

Novel aspects on signal-transduction in the pancreatic β-cell

Berggren PO; Leibiger IB
Editorial comment: NATURE MEDICINE. 2006;12(1):34-36

Sirt1: a metabolic master switch that modulates lifespan

Leibiger IB; Berggren PO
Editorial comment: CELL METABOLISM. 2005;2(2):80-82

A SIRTain role in pancreatic β cell function

Leibiger IB; Berggren PO
Review: FEBS LETTERS. 2002;532(1-2):1-6

Insulin feedback action on pancreatic β-cell function

Leibiger IB; Leibiger B; Berggren PO
Review: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2002;283(6):E1113-E1122

Phosphorylated inositol compounds in β-cell stimulus-response coupling

Barker CJ; Leibiger IB; Leibiger B; Berggren PO
Published conference paper: BIOCHEMICAL SOCIETY TRANSACTIONS. 2002;30(2):312-317

Short-term regulation of insulin gene transcription

Leibiger B; Moede T; Uhles S; Berggren PO; Leibiger IB
Published conference paper: DIABETES. 2001;50:S15-S19

Online monitoring of stimulus-induced gene expression in pancreatic β-cells

Moede T; Leibiger B; Berggren PO; Leibiger IB

Anställningar

Senior Forskningsspecialist, Molekylär medicin och kirurgi, Karolinska Institutet, 2022-

Examina och utbildning

Docent, Cellbiologi, Karolinska Institutet, 2004

Artiklar

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Anställningar

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