Helder Andre

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Ansvarig för Molekylär och Cellulär Forskning vid S:t Eriks Ögonsjukhus
och Forskargruppsledare för Retina gruppen.

Artiklar

Article: FASEB JOURNAL. 2024;38(17):e70020
Accelerated maturation of ARPE-19 cells for the translational assessment of gene therapy
Bernd J; Plastino F; Karayannis JJ; Kvanta A; Locri F; Andre H
Article: NATURE COMMUNICATIONS. 2024;15(1):7438
Interim safety and efficacy of gene therapy for RLBP1-associated retinal dystrophy: a phase 1/2 trial.
Kvanta A; Rangaswamy N; Holopigian K; Watters C; Jennings N; Liew MSH; Bigelow C; Grosskreutz C; Burstedt M; Venkataraman A; Westman S; Geirsdottir A; Stasi K; André H
Article: BRITISH JOURNAL OF OPHTHALMOLOGY. 2024;108(4):578-587
Obesity paradox in uveal melanoma: high body mass index is associated with low metastatic risk
Sabazade S; Opalko A; Herrspiegel C; Gill VT; Plastino F; Andre H; Stalhammar G
Article: FASEB JOURNAL. 2024;38(5):e23533
Mitigation of human iris angiogenesis through uPAR/LRP-1 interaction antagonism in an organotypic ex vivo model
Pesce NA; Plastino F; Reyes-Goya C; Bernd J; Pavone V; Dal Monte M; Kvanta A; Locri F; Andre H
Article: MOLECULAR NUTRITION & FOOD RESEARCH. 2024;68(3):e2200623
Exploring the Potential of Wild Olive (Acebuche) Oil as a Pharm-Food to Prevent Ocular Hypertension and Fibrotic Events in the Retina of Hypertensive Mice
Santana-Garrido A; Reyes-Goya C; Andre H; Vazquez CM; Mate A
Article: HELIYON. 2024;10(1):e23831
Retinoblastoma vulnerability to combined de novo and salvage pyrimidine ribonucleotide synthesis pharmacologic blockage
Mollick T; Darekar S; Dalarun B; Plastino F; Zhang J; Fernandez AP; Alkasalias T; Andre H; Lain S
Journal article: ACTA OPHTHALMOLOGICA. 2024;102(S279)
Extracellular vesicles mirror the beneficial effect of wild olive (acebuche) oil in hypertensive‐like retinal pigment epithelial cells
Santana‐Garrido Á; Goya CR; Espinosa‐Martín P; Andre H; Vázquez CM; Mate A
Journal article: NAT CARDIOVASC RES. 2023;2(12):1120-1124
Report from the 2023 workshop on endothelial permeability, edema and inflammation
Vestweber D; Claesson-Welsh L; McDonald DM; Williams T; Schwartz MA; Scallan J; Gavins FNE; van Buul J; Gamble J; Vadas M; Annex BH; Messe SR; Perretti M; Andre H; Ferrara N; Hla T; Nourshargh S; Simons M
Article: EXPERIMENTAL EYE RESEARCH. 2023;237:109674
Anatomy of the complete mouse eye vasculature explored by light-sheet fluorescence microscopy exposes subvascular-specific remodeling in development and pathology
Krimpenfort LT; Garcia-Collado M; van Leeuwen T; Locri F; Luik A-L; Queiro-Palou A; Kanatani S; Andre H; Uhlen P; Jakobsson L
Journal article: JOURNAL OF BIOLOGICAL ENGINEERING. 2023;17(1):58
Efficient targeting of HIF-1α mediated by YC-1 and PX-12 encapsulated niosomes: potential application in colon cancer therapy
Bakand A; Moghaddam SV; Naseroleslami M; Andre H; Mousavi-Niri N; Alizadeh E
Article: BMC CANCER. 2023;23(1):277
A serum protein signature at the time of Uveal Melanoma diagnosis predicts long-term patient survival
Herrspiegel C; Plastino F; Lardner E; Seregard S; Williams PA; Andre H; Stalhammar G
Article: MOLECULAR THERAPY. 2023;31(3):825-846
Photoreceptor laminin drives differentiation of human pluripotent stem cells to photoreceptor progenitors that partially restore retina function
Tay HG; Andre H; Chrysostomou V; Adusumalli S; Guo J; Ren X; Tan WS; Tor JE; Moreno-Moral A; Plastino F; Bartuma H; Cai Z; Tun SBB; Barathi VA; Wei GTS; Grenci G; Chong LY; Holmgren A; Kvanta A; Guy CJ; Petretto E; Tryggvason K
Article: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2022;78(4):915-932
Hypertension secondary to nitric oxide depletion produces oxidative imbalance and inflammatory/fibrotic outcomes in the cornea of C57BL/6 mice
Santana-Garrido A; Reyes-Goya C; Arroyo-Barrios A; Andre H; Vazquez CM; Mate A
Article: STEM CELL REPORTS. 2022;17(6):1458-1475
Molecular profiling of stem cell-derived retinal pigment epithelial cell differentiation established for clinical translation
Petrus-Reurer S; Lederer AR; Baque-Vidal L; Douagi I; Pannagel B; Khven I; Aronsson M; Bartuma H; Wagner M; Wrona A; Efstathopoulos P; Jaberi E; Willenbrock H; Shimizu Y; Villaescusa JC; Andre H; Sundstrom E; Bhaduri A; Kriegstein A; Kvanta A; La Manno G; Lanner F
Article: CELLS. 2022;11(11):1778
Hormetic Heat Shock Enhances Autophagy through HSF1 in Retinal Pigment Epithelium Cells
Amirkavei M; Plastino F; Kvanta A; Kaarniranta K; Andre H; Koskelainen A
Article: CHEMICAL ENGINEERING JOURNAL. 2022;429:132523
Corneal endothelial cell sheet bioengineering from neural crest cell-derived adipose stem cells on novel thermo-responsive elastin-mimetic dendrimers decorated with RGD
Khalili M; Zarebkohan A; Dianat-Moghadam H; Panahi M; Andre H; Alizadeh E
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2021;25(22):10480-10493
An imbalance in autophagy contributes to retinal damage in a rat model of oxygen-induced retinopathy
Pesce NA; Canovai A; Plastino F; Lardner E; Kvanta A; Cammalleri M; Andre H; Dal Monte M
Article: FOODS. 2021;10(9):1993
Anti-Inflammatory Action of Dietary Wild Olive (Acebuche) Oil in the Retina of Hypertensive Mice
Santana-Garrido A; Reyes-Goya C; Milla-Navarro S; de la Villa P; Andre H; Vazquez CM; Mate A
Article: SCIENTIFIC REPORTS. 2021;11(1):11856
The monoamine stabilizer OSU6162 has anxiolytic-like properties and reduces voluntary alcohol intake in a genetic rat model of depression
Melas PA; Wirf M; Andre H; Jayaram-Lindstrom N; Mathe AA; Steensland P
Article: EXPERIMENTAL EYE RESEARCH. 2021;206:108518
Echinomycin mitigates ocular angiogenesis by transcriptional inhibition of the hypoxia-inducible factor-1
Plastino F; Santana-Garrido A; Pesce NA; Aronsson M; Lardner E; Mate A; Kvanta A; Vazquez CM; Andre H
Article: CELLS. 2021;10(1):177
Autophagy Involvement in the Postnatal Development of the Rat Retina
Pesce NA; Canovai A; Lardner E; Cammalleri M; Kvanta A; Andre H; Dal Monte M
Article: TRANSLATIONAL VISION SCIENCE & TECHNOLOGY. 2021;10(1):22
When Is a Control Not a Control? Reactive Microglia Occur Throughout the Control Contralateral Pathway of Retinal Ganglion Cell Projections in Experimental Glaucoma
Tribble JR; Kokkali E; Otmani A; Plastino F; Lardner E; Vohra R; Kolko M; Andre H; Morgan JE; Williams PA
Article: MOLECULAR VISION. 2021;27:161-178
NADPH oxidase-induced oxidative stress in the eyes of hypertensive rats
Santana-Garrido A; Reyes-Goya C; Fernandez-Bobadilla C; Blanca AJ; Andre H; Mate A; Vazquez CM
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2020;98(11):1629-1638
Gaining insight on mitigation of rubeosis iridis by UPARANT in a mouse model associated with proliferative retinopathy
Locri F; Pesce NA; Aronsson M; Cammalleri M; De Rosa M; Pavone V; Bagnoli P; Kvanta A; Dal Monte M; Andre H
Article: ANTIOXIDANTS. 2020;9(9):E885-885
Retinoprotective Effect of Wild Olive (Acebuche) Oil-Enriched Diet against Ocular Oxidative Stress Induced by Arterial Hypertension
Santana-Garrido A; Reyes-Goya C; Carmen Perez-Camino M; Andre H; Mate A; Vazquez CM
Article: LIFE SCIENCES. 2020;257:118072
Sunitinib-induced oxidative imbalance and retinotoxic effects in rats
Santana-Garrido A; Reyes-Goya C; Andre H; Aramburu O; Mate A; Vazquez CM
Article: STEM CELLS TRANSLATIONAL MEDICINE. 2020;9(8):936-953
Preclinical safety studies of human embryonic stem cell-derived retinal pigment epithelial cells for the treatment of age-related macular degeneration
Petrus-Reurer S; Kumar P; Sanchez SP; Aronsson M; Andre H; Bartuma H; Reyes AP; Nandrot EF; Kvanta A; Lanner F
Article: ELIFE. 2020;9:e54056
Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin
Smith RO; Ninchoji T; Gordon E; Andre H; Dejana E; Vestweber D; Kvanta A; Claesson-Welsh L
Article: STEM CELL REPORTS. 2020;14(4):648-662
Generation of Retinal Pigment Epithelial Cells Derived from Human Embryonic Stem Cells Lacking Human Leukocyte Antigen Class I and II
Petrus-Reurer S; Winblad N; Kumar P; Gorchs L; Chrobok M; KathleenWagner A; Bartuma H; Lardner E; Aronsson M; Reyes AP; Andre H; Alici E; Kaipe H; Kvanta A; Lanner F
Article: NATURE COMMUNICATIONS. 2020;11(1):1609
Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells
Reyes AP; Petrus-Reurer S; Sanchez SP; Kumar P; Douagi I; Bartuma H; Aronsson M; Westman S; Lardner E; Andre H; Falk A; Nandrot EF; Kvanta A; Lanner F
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020;21(6):E2063-2063
Induction of Heat Shock Protein 70 in Mouse RPE as an In Vivo Model of Transpupillary Thermal Stimulation
Amirkavei M; Pitkanen M; Kaikkonen O; Kaarniranta K; Andre H; Koskelainen A
Article: BRITISH JOURNAL OF OPHTHALMOLOGY. 2020;104(1):26-32
Ruthenium-106 versus iodine-125 plaque brachytherapy of 571 choroidal melanomas with a thickness of ≥5.5 mm
Fili M; Trocme E; Bergman L; See TRO; Andre H; Bartuma K; Girnita L; All-Eriksson C; Seregard S; Stalhammar G
Article: JOURNAL OF CLINICAL MEDICINE. 2019;8(12):E2217-2217
Identification of Diagnostic and Prognostic microRNAs for Recurrent Vitreous Hemorrhage in Patients with Proliferative Diabetic Retinopathy
Mammadzada P; Bayle J; Gudmundsson J; Kvanta A; Andre H
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2019;97(9):1273-1283
UPARANT is an effective antiangiogenic agent in a mouse model of rubeosis iridis
Locri F; Dal Monte M; Aronsson M; Cammalleri M; De Rosa M; Pavone V; Kvanta A; Bagnoli P; Andre H
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2019;39(7):1402-1418
Intussusceptive Vascular Remodeling Precedes Pathological Neovascularization
Ali Z; Mukwaya A; Biesemeier A; Ntzouni M; Ramskold D; Giatrellis S; Mammadzada P; Cao R; Lennikov A; Marass M; Gerri C; Hildesjo C; Taylor M; Deng Q; Peebo B; del Peso L; Kvanta A; Sandberg R; Schraermeyer U; Andre H; Steffensen JF; Lagali N; Cao Y; Kele J; Dahl Jensen L
Article: JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE. 2018;29(11):170
Cell sheet biofabrication by co-administration of mesenchymal stem cells secretome and vitamin C on thermoresponsive polymer
Shotorbani BB; Andre H; Barzegar A; Zarghami N; Salehi R; Alizadeh E
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2018;(133)
Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis
Locri F; Aronsson M; Beaujean O; Kvanta A; Andre H
Journal article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2018;(133)
Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis
Locri F; Aronsson M; Beaujean O; Kvanta A; André H
Article: NUTRIENTS. 2017;9(10):E1079-1079
Efficacy of a Fatty Acids Dietary Supplement in a Polyethylene Glycol-Induced Mouse Model of Retinal Degeneration
Cammalleri M; Dal Monte M; Locri F; Lardner E; Kvanta A; Rusciano D; Andre H; Bagnoli P
Article: SCIENTIFIC REPORTS. 2017;7:42546
Gene Transfer of Prolyl Hydroxylase Domain 2 Inhibits Hypoxia-inducible Angiogenesis in a Model of Choroidal Neovascularization
Takei A; Ekstrom M; Mammadzada P; Aronsson M; Yu M; Kvanta A; Andre H
Article: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2017;58(2):1314-1322
Integration of Subretinal Suspension Transplants of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells in a Large-Eyed Model of Geographic Atrophy
Petrus-Reurer S; Bartuma H; Aronsson M; Westman S; Lanner F; Andre H; Kvanta A
Article: PLOS ONE. 2017;12(6):e0180235
A novel in vivo model of puncture-induced iris neovascularization
Beaujean O; Locri F; Aronsson M; Kvanta A; Andre H
Article: ACTA OPHTHALMOLOGICA. 2016;94(8):805-814
Differential hypoxic response of human choroidal and retinal endothelial cells proposes tissue heterogeneity of ocular angiogenesis
Mammadzada P; Gudmundsson J; Kvanta A; Andre H
Article: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2016;57(6):2600-2611
The Urokinase Receptor-Derived Peptide UPARANT Mitigates Angiogenesis in a Mouse Model of Laser-Induced Choroidal Neovascularization
Cammalleri M; Dal Monte M; Locri F; Lista L; Aronsson M; Kvanta A; Rusciano D; De Rosa M; Pavone V; Andre H; Bagnoli P
Article: STEM CELL REPORTS. 2016;6(1):9-17
Xeno-Free and Defined Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells Functionally Integrate in a Large-Eyed Preclinical Model
Reyes AP; Petrus-Reurer S; Antonsson L; Stenfelt S; Bartuma H; Panula S; Mader T; Douagi I; Andre H; Hovatta O; Lanner F; Kvanta A
Article: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2015;56(11):6591-6604
Hypoxia-Inducible Factor-1α Is Associated With Sprouting Angiogenesis in the Murine Laser-Induced Choroidal Neovascularization Model
Andre H; Tunik S; Aronsson M; Kvanta A
Article: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2015;56(4):2423-2430
In Vivo Imaging of Subretinal Bleb-Induced Outer Retinal Degeneration in the Rabbit
Bartuma H; Petrus-Reurer S; Aronsson M; Westman S; Andre H; Kvanta A
Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2014;44(10):989-999
HIF-1α and HIF-2α induce angiogenesis and improve muscle energy recovery
Niemi H; Honkonen K; Korpisalo P; Huusko J; Kansanen E; Merentie M; Rissanen TT; Andre H; Pereira T; Poellinger L; Alitalo K; Yla-Herttuala S
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2008;283(43):29375-29384
Identification of an Alternative Mechanism of Degradation of the Hypoxia-inducible Factor-1α
Andre H; Pereira TS
Article: FASEB JOURNAL. 2005;19(8):1365-1367
Stabilized HIF-1α is superior to VEGF for angiogenesis in skeletal muscle via adeno-associated virus gene transfer
Pajusola K; Künnapuu J; Vuorikoski S; Soronen J; André H; Pereira T; Korpisalo P; Ylä-Herttuala S; Poellinger L; Alitalo K
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Alla övriga publikationer

Review: CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE. 2024;:S0008-4182(23)00385-X
Prognostic implications of tenascin C in peripheral blood and primary tumours at the time of uveal melanoma diagnosis.
Herrspiegel C; Plastino F; André H; Stålhammar G
Preprint: BIORXIV. 2022
Novel subthreshold retinal laser treatment with ERG-based thermal dosimetry activates hormetic heat response in pig RPEin vivo
Amirkavei M; Kaikkonen O; Turunen T; Meller A; Åhlgren J; Kvanta A; André H; Koskelainen A
Review: ACTA OPHTHALMOLOGICA. 2021;99(8):e1255-e1262
MicroRNAs and the HIF/VEGF axis in ocular neovascular diseases
Plastino F; Pesce NA; Andre H
Review: LIFE SCIENCES. 2021;276:119373
Liver bioengineering: Recent trends/advances in decellularization and cell sheet technologies towards translation into the clinic
Asadi M; Khalili M; Lotfi H; Moghaddam SV; Zarghami N; Andre H; Alizadeh E
Preprint: BIORXIV. 2021
Molecular profiling of retinal pigment epithelial cell differentiation for therapeutic use
Petrus-Reurer S; Lederer A; Baqué-Vidal L; Douagi I; Pannagel B; Aronsson M; Bartuma H; Wagner M; André H; Sundström E; Bhaduri A; Kriegstein A; Kvanta A; Manno GL; Lanner F
Review: JOURNAL OF CELLULAR PHYSIOLOGY. 2020;236(5):3275-3303
Corneal endothelium tissue engineering: An evolution of signaling molecules, cells, and scaffolds toward 3D bioprinting and cell sheets
Khalili M; Asadi M; Kahroba H; Soleyman MR; Andre H; Alizadeh E
Review: NUTRIENTS. 2020;12(9):E2871-2871
Potential Therapeutic Benefit of NAD⁺Supplementation for Glaucoma and Age-Related Macular Degeneration
Cimaglia G; Votruba M; Morgan JE; Andre H; Williams PA
Review: CELLULAR AND MOLECULAR LIFE SCIENCES. 2020;77(5):819-833
The role of hypoxia-inducible factors in neovascular age-related macular degeneration: a gene therapy perspective
Mammadzada P; Corredoira PM; Andre H
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2018;19(12):E3846-3846
The Different Facades of Retinal and Choroidal Endothelial Cells in Response to Hypoxia
Alizadeh E; Mammadzada P; Andre H
Thesis / dissertation: 2009
Assessment of HIF-1alpha function and identification of a novel degradation mechanism
André, Helder
Thesis / dissertation: 2005
Analysis of HIF-1alpha degradation and function
André, Helder

Anställningar

Anknuten till Forskning, Klinisk neurovetenskap, Karolinska Institutet, 2023-2026

Examina och utbildning

Medicine Doktorsexamen, Institutionen för cell- och molekylärbiologi, Karolinska Institutet, 2009
LICENTIATEXAMEN, Institutionen för cell- och molekylärbiologi, Karolinska Institutet, 2005

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