Håkan Westerblad
Professor Emeritus/Emerita
E-postadress: hakan.westerblad@ki.se
Telefon: +46852487253
Besöksadress: Solnavägen 9, Biomedicum C5, 17165 Solna
Postadress: C3 Fysiologi och farmakologi, C3 FyFa Medicinsk hjärt- och skelettmuskelforskning, 171 77 Stockholm
Om mig
- Professor i cellulär muskelfysiologi vid institutionen för fysiologi och farmakologi.
Håkan Westerblad är född 1956 i Solna. Han läste medicin vid Karolinska Institutet och tog läkarexamen 1984. Han började sedan forska inom fysiologi och disputerade 1989 på en avhandling om muskeltrötthet. Under åren 1990-1992 gjorde Håkan Westerblad en post doc vid University of Sydney i Australien, återvände sedan till Karolinska Institutet, där han blev docent i fysiologi 1993.
Håkan Westerblad har därefter fortsatt att forska på funktionen hos framför allt skelettmuskulatur. Han har innehaft tjänster som forskarassistent och forskare vid institutionen för fysiologi och farmakologi, inkluderande en forskartjänst på Vetenskapsrådet 2002‒2008. Vid sidan av forskningen deltar Håkan Westerblad i grundutbildningen av studenter på ett flertal utbildningsprogram och är vikarierande studierektor på forskarutbildningen vid institutionen.
Håkan Westerblad utnämndes den 1 september 2003 till professor i cellulär muskelfysiologi vid Karolinska Institutet. Han har också blivit utnämnd hedersdoktor vid Lithuanian Sports University.
Forskningsbeskrivning
- En central del i vår forskning är studier av cellulära orsaker till att skelettmuskler blir svagare och långsammare vid uttröttning. Med utgångspunkt från dessa studier undersöker vi även grundläggande mekanismer för hur muskelceller anpassar sig till träning och därmed blir mer uthålliga eller starkare.
Vi studerar även motsatsen, dvs varför muskler blir svagare och mindre uthålliga vid olika sjukdomstillstånd, t ex mitokondriella myopatier. En stor del vår forskning kretsar kring det komplexa samspelet mellan kraftproduktion, cellulär Ca2+-hantering, mitokondriefunktion och fria radikaler (reactive oxygen/nitrogen species).
Artiklar
- Journal article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2024;:1-3
- Journal article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2024;:1-2
- Article: SCIENTIFIC REPORTS. 2024;14(1):689
- Article: FASEB JOURNAL. 2023;37(6):e22978
- Article: STAR PROTOCOLS. 2023;4(2):102260
- Article: ANTIOXIDANTS. 2022;12(1):16
- Article: ISCIENCE. 2022;25(12):105654
- Article: ACTA PHYSIOLOGICA. 2022;236(3):e13869
- Article: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE. 2022;13(5):2551-2561
- Article: ARTHRITIS RESEARCH & THERAPY. 2022;24(1):156
- Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2022;122(1):255-266
- Article: FASEB JOURNAL. 2021;35(11):e21988
- Article: DISEASE MODELS & MECHANISMS. 2021;14(9):dmm048981
- Article: ARTHRITIS & RHEUMATOLOGY. 2021;73(5):848-857
- Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2021;108(3):446-457
- Article: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE. 2020;11(6):1747-1757
- Article: MEDICINA-LITHUANIA. 2020;56(8):E395-395
- Article: SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS. 2020;30(6):998-1007
- Article: EXPERIMENTAL GERONTOLOGY. 2020;134:110880
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2020;598(4):773-787
- Article: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2020;1131:7-26
- Article: INTERNATIONAL JOURNAL OF TRYPTOPHAN RESEARCH. 2020;13:1178646920978241
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2019;317(6):C1304-C1312
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2019;317(5):C900-C909
- Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2019;119(9):1951-1958
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2019;597(17):4615-4625
- Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2019;4(4):509-523
- Article: JOURNAL OF GENERAL PHYSIOLOGY. 2019;151(4):567-577
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2019;316(2):C246-C251
- Article: CELL CALCIUM. 2018;76:87-100
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2018;596(18):4427-4442
- Article: COLD SPRING HARBOR PERSPECTIVES IN MEDICINE. 2018;8(2):a029710
- Article: FRONTIERS IN PHYSIOLOGY. 2018;9:1111
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2017;595(24):7413-7426
- Article: FASEB JOURNAL. 2017;31(11):4809-4820
- Article: NATURE PROTOCOLS. 2017;12(9):1763-1776
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2017;595(5):1657-1670
- Article: FRONTIERS IN PHYSIOLOGY. 2017;8:712
- Article: PLOS ONE. 2017;12(6):e0179925
- Article: PLOS ONE. 2017;12(2):e0169146
- Article: PHYSIOLOGY & BEHAVIOR. 2017;168:55-61
- Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2016;116(11-12):2215-2224
- Article: CRITICAL CARE. 2016;20(1):254
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2016;310(10):C836-C840
- Article: BASIC RESEARCH IN CARDIOLOGY. 2016;111(3):34
- Article: MATHEMATICAL AND COMPUTER MODELLING OF DYNAMICAL SYSTEMS. 2016;22(1):21-38
- Article: PLOS ONE. 2016;11(12):e0167090
- Article: FRONTIERS IN PHYSIOLOGY. 2016;7:252
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(50):15492-15497
- Article: HUMAN MOLECULAR GENETICS. 2015;24(23):6580-6587
- Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(10):1907-1914
- Article: DISCOVERIES (CRAIOVA). 2015;3(3):e50
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2015;593(2):457-472
- Article: SKELETAL MUSCLE. 2015;5:26
- Article: SKELETAL MUSCLE. 2015;5:20
- Article: MAMMALIAN GENOME. 2014;25(9-10):464-472
- Article: CARDIOVASCULAR RESEARCH. 2014;103(1):90-99
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2014;592(9):2003-2012
- Article: PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 2014;466(3):577-585
- Article: PLOS ONE. 2014;9(9):e108601
- Article: JOURNAL OF APPLIED PHYSIOLOGY. 2013;115(8):1191-1195
- Article: ARTHRITIS RESEARCH & THERAPY. 2013;15(4):R83
- Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(8):1390-1399
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2013;591(15):3739-3748
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2012;590(23):6187-6197
- Article: BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 2012;11(7):947-957
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2012;590(15):3575-3583
- Article: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2012;740:27-43
- Article: PLOS ONE. 2012;7(7):e42038
- Article: ANTIOXIDANTS & REDOX SIGNALING. 2011;15(9):2455-2464
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2011;589(7):1791-1801
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2010;588(21):4275-4288
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2010;299(3):E364-E373
- Article: EXPERIMENTAL PHYSIOLOGY. 2010;95(8):892-898
- Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2010;223(2):376-383
- Article: FASEB JOURNAL. 2010;24(2):570-578
- Article: ACTA PHYSIOLOGICA. 2010;198(2):133-142
- Article: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2010;682:279-296
- Article: ACTA PHYSIOLOGICA. 2010;198(1):91-98
- Article: JOURNAL OF APPLIED PHYSIOLOGY. 2009;107(6):1935-1942
- Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(11):3280-3289
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2009;587(19):4717-4724
- Article: JOURNAL OF BIOMECHANICS. 2009;42(11):1628-1634
- Article: FASEB JOURNAL. 2009;23(6):1728-1738
- Article: MUSCLE & NERVE. 2009;39(5):674-682
- Article: HUMAN MOLECULAR GENETICS. 2009;18(2):278-288
- Article: FASEB JOURNAL. 2008;22(11):3919-3924
- Article: JOURNAL OF BIOMECHANICS. 2008;41(11):2422-2429
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2008;586(11):2799-2805
- Article: ACTA PHYSIOLOGICA. 2008;192(3):413-420
- Article: JOURNAL OF NEUROSCIENCE. 2008;28(8):1904-1915
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2008;586(1):175-184
- Article: JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 2008;29(1):25-36
- Article: BIOCHEMICAL PHARMACOLOGY. 2007;74(11):1628-1635
- Article: EMBO JOURNAL. 2007;26(21):4535-4545
- Article: ACTA PHYSIOLOGICA. 2007;191(2):131-137
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2007;293(3):C1154-C1159
- Article: DIABETES. 2007;56(4):1136-1142
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2007;579(2):527-534
- Article: CARDIOVASCULAR RESEARCH. 2007;73(2):376-385
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;350(1):202-207
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2006;575(1):251-262
- Article: DIABETES. 2006;55(7):2077-2083
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2006;291(1):C147-C154
- Article: CIRCULATION RESEARCH. 2006;98(12):1514-1519
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2006;572(2):551-559
- Article: ACTA PHYSIOLOGICA. 2006;186(1):59-66
- Article: HUMAN MOLECULAR GENETICS. 2005;14(8):1069-1076
- Article: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2005;38(4):655-663
- Article: JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 2005;26(2-3):135-141
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2004;287(6):E1125-E1131
- Article: PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 2004;448(5):533-538
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2004;554(2):309-320
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2003;553(2):523-531
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2003;552(2):393-402
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2003;551(1):5-12
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2003;551(1):179-190
- Article: MUSCLE & NERVE. 2003;27(4):442-448
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2003;547(3):789-796
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2003;547(2):395-403
- Article: FASEB JOURNAL. 2003;16(14):301-303
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2002;99(23):15066-15071
- Article: PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 2002;444(6):692-699
- Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2002;166(4):479-484
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2002;283(1):C42-C47
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2002;282(6):C1306-C1312
- Article: PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 2002;443(5-6):836-842
- Article: APPLIED PHYSIOLOGY NUTRITION AND METABOLISM. 2002;27(1):83-96
- Article: PHYSIOLOGY. 2002;17:17-21
- Article: CELL BIOLOGY INTERNATIONAL. 2002;26(10):911-920
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2001;535(1):155-164
- Article: MOLECULAR AND CELLULAR NEUROSCIENCE. 2001;18(1):56-67
- Article: CIRCULATION RESEARCH. 2001;88(12):1299-1305
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2001;533(3):639-649
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2001;533(2):379-388
- Article: NATURE NEUROSCIENCE. 2001;4(6):597-604
- Article: FASEB JOURNAL. 2001;15(2):309-311
- Article: JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 2001;22(3):265-275
- Article: ACTA PHYSIOLOGICA. 2000;170(1):45-49
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2000;526(3):597-611
- Article: FASEB JOURNAL. 2000;14(7):982-990
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2000;278(3):R598-R603
- Article: JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 2000;21(7):621-628
- Article: ACTA PHYSIOLOGICA. 1999;166(4):341-347
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1999;96(6):3281-3286
- Article: JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 1999;20(1):19-32
- Article: CELL CALCIUM. 1998;24(2):105-115
- Article: JOURNAL OF APPLIED PHYSIOLOGY. 1998;85(2):478-483
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 1998;510(1):269-277
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 1998;509(2):577-586
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 1998;509(2):565-575
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998;95(11):6145-6150
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 1997;500(1):193-204
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1997;272(3):C870-C874
- Article: JOURNAL OF GENERAL PHYSIOLOGY. 1997;109(3):385-399
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1997;272(2):E245-E247
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 1997;498(3):587-600
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 1996;495(1):15-22
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 1996;493(1):211-217
- Article: ACTA PHYSIOLOGICA. 1996;156(4):441-446
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(43):25613-25618
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 1995;484(3):737-742
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 1995;482(2):383-390
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Alla övriga publikationer
- Preprint: BIORXIV. 2023;BIORXIV
- Letter: AMERICAN JOURNAL OF HUMAN GENETICS. 2022;109(5):973
- Editorial comment: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2016;48(11):2339-2342
- Review: JOURNAL OF PHYSIOLOGY-LONDON. 2016;594(18):5149-5160
- Editorial comment: PLOS GENETICS. 2015;11(1):e1004908
- Review: JOURNAL OF PHYSIOLOGY-LONDON. 2013;591(18):4405-4413
- Editorial comment: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2013;113(4):823
- Review: FRONTIERS IN PHYSIOLOGY. 2012;3:46
- Review: JOURNAL OF PHYSIOLOGY-LONDON. 2011;589(21):5021-5031
- Review: ANTIOXIDANTS & REDOX SIGNALING. 2011;15(9):2487-2499
- Published conference paper: JOURNAL OF PHYSIOLOGY-LONDON. 2011;589(9):2119-2127
- Editorial comment: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2010;110(6):1095-1098
- Review: EXPERIMENTAL CELL RESEARCH. 2010;316(18):3093-3099
- Letter: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2010;110(3):661-662
- Review: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2010;110(1):1-15
- Published conference paper: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY. 2009;36(3):334-339
- Review: CURRENT OPINION IN PHARMACOLOGY. 2008;8(3):339-345
- Review: PHYSIOLOGICAL REVIEWS. 2008;88(1):287-332
- Review: JOURNAL OF APPLIED PHYSIOLOGY. 2008;104(1):296-305
- Editorial comment: JOURNAL OF PHYSIOLOGY-LONDON. 2007;583(1):3-4
- Letter: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2007;292(1):c613-c614
- Review: NEUROSCIENCE. 2005;133(1):59-77
- Editorial comment: SCIENCE. 2004;305(5687):1112-1113
- Published conference paper: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2003;538:563-571
- Review: CURRENT OPINION IN RHEUMATOLOGY. 2002;14(6):648-652
- Review: JOURNAL OF PHYSIOLOGY-LONDON. 2001;536(3):657-665
- Published conference paper: ACTA PHYSIOLOGICA. 2001;171(3):259-265
- Review: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2000;83(2-3):166-174
- Published conference paper: ACTA PHYSIOLOGICA. 1998;162(3):285-293
- Published conference paper: ACTA PHYSIOLOGICA. 1998;162(3):253-260
- Published conference paper: ACTA PHYSIOLOGICA. 1996;156(3):407-416
- Published conference paper: ACTA PHYSIOLOGICA. 1996;156(3):193-202
- Review: EXPERIMENTAL PHYSIOLOGY. 1995;80(4):497-527
- Other: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1995;1244(1):229-232
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